POLE Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description polymerase (DNA directed), epsilon, catalytic subunit|This gene encodes the catalytic subunit of DNA polymerase epsilon. The enzyme is involved in DNA repair and chromosomal DNA replication. Mutations in this gene have been associated with colorectal cancer 12 and facial dysmorphism, immunodeficiency, livedo, and short stature. [provided by RefSeq, Sep 2013] (NCBI Entrez Gene Database, 5426)
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Genes

446 genes differentially expressed following the POLE gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
SLC28A2 solute carrier family 28 (concentrative nucleoside transporter), member 2 3.06475
LIPK lipase, family member K 2.97204
MTMR11 myotubularin related protein 11 2.97204
ZNF879 zinc finger protein 879 2.97204
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 2.97204
FBXO4 F-box protein 4 2.97204
RHBDL1 rhomboid, veinlet-like 1 (Drosophila) 2.97204
TFF3 trefoil factor 3 (intestinal) 2.97204
M1AP meiosis 1 associated protein 2.97204
SCUBE1 signal peptide, CUB domain, EGF-like 1 2.97204
EYA4 EYA transcriptional coactivator and phosphatase 4 2.97204
RFX4 regulatory factor X, 4 (influences HLA class II expression) 2.97204
MRPL53 mitochondrial ribosomal protein L53 2.97204
ENOX1 ecto-NOX disulfide-thiol exchanger 1 2.97204
ALK anaplastic lymphoma receptor tyrosine kinase 2.97204
APC2 adenomatosis polyposis coli 2 2.97204
NAIF1 nuclear apoptosis inducing factor 1 2.97204
TOR4A torsin family 4, member A 2.97204
PCDHB9 protocadherin beta 9 2.97204
CNTNAP4 contactin associated protein-like 4 2.97204
RAD21L1 RAD21-like 1 (S. pombe) 2.97204
PZP pregnancy-zone protein 2.97204
S1PR5 sphingosine-1-phosphate receptor 5 2.97204
TSKS testis-specific serine kinase substrate 2.97204
NALCN sodium leak channel, non selective 2.97204
VEGFD vascular endothelial growth factor D 2.97204
DIO1 deiodinase, iodothyronine, type I 2.97204
H3C4 H3 clustered histone 4 2.97204
ANKRD45 ankyrin repeat domain 45 2.97204
MYL11 myosin light chain 11 2.97204
ZNF112 zinc finger protein 112 2.97204
CFAP141 cilia and flagella associated protein 141 2.97204
PFN4 profilin family, member 4 2.97204
PCDHAC1 protocadherin alpha subfamily C, 1 2.97204
ZNF804A zinc finger protein 804A 2.97204
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 2.97204
CRYGN crystallin, gamma N 2.8369
SLC37A2 solute carrier family 37 (glucose-6-phosphate transporter), member 2 2.8369
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 2.8369
TTC21A tetratricopeptide repeat domain 21A 2.8369
NANOS2 nanos homolog 2 (Drosophila) 2.8369
RSPH6A radial spoke head 6 homolog A (Chlamydomonas) 2.8369
GPR6 G protein-coupled receptor 6 2.8369
LHCGR luteinizing hormone/choriogonadotropin receptor 2.8369
LDHD lactate dehydrogenase D 2.8369
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 2.8369
FABP6 fatty acid binding protein 6, ileal 2.8369
CPLX4 complexin 4 2.8369
RP1L1 retinitis pigmentosa 1-like 1 2.8369
RUNDC3A RUN domain containing 3A 2.8369
ALG1L2 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase-like 2 2.8369
VCX variable charge, X-linked 2.8369
IGFL3 IGF-like family member 3 2.8369
AKAP3 A kinase (PRKA) anchor protein 3 2.8369
CCL5 chemokine (C-C motif) ligand 5 2.8369
AVPR2 arginine vasopressin receptor 2 2.8369
PHYHIPL phytanoyl-CoA 2-hydroxylase interacting protein-like 2.8369
CXCL3 chemokine (C-X-C motif) ligand 3 2.8369
GADL1 glutamate decarboxylase-like 1 2.8369
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa 2.8369
CRX cone-rod homeobox 2.8369
MRO maestro 2.8369
CD68 CD68 molecule 2.8369
KIAA2012 KIAA2012 2.8369
KCNIP3 Kv channel interacting protein 3, calsenilin 2.8369
GMFG glia maturation factor, gamma 2.8369
TRIM72 tripartite motif containing 72, E3 ubiquitin protein ligase 2.8369
CA1 carbonic anhydrase I 2.8369
LMO1 LIM domain only 1 (rhombotin 1) 2.8369
USP50 ubiquitin specific peptidase 50 2.8369
CSMD3 CUB and Sushi multiple domains 3 2.8369
SPOCD1 SPOC domain containing 1 2.8369
LBP lipopolysaccharide binding protein 2.8369
SYCE3 synaptonemal complex central element protein 3 2.8369
CIITA class II, major histocompatibility complex, transactivator 2.8369
PAPPA2 pappalysin 2 2.8369
FLI1 Fli-1 proto-oncogene, ETS transcription factor 2.8369
DPPA3 developmental pluripotency associated 3 2.8369
PECAM1 platelet/endothelial cell adhesion molecule 1 2.8369
MOGAT3 monoacylglycerol O-acyltransferase 3 2.8369
SCARA5 scavenger receptor class A, member 5 2.8369
SLC67A1 solute carrier family 67 member 1 2.8369
AHNAK2 AHNAK nucleoprotein 2 2.8369
DNAAF1 dynein, axonemal, assembly factor 1 2.8369
STMN4 stathmin-like 4 2.8369
POM121L2 POM121 transmembrane nucleoporin-like 2 2.8369
ANO3 anoctamin 3 2.8369
KLB klotho beta 2.8369
PROC protein C (inactivator of coagulation factors Va and VIIIa) 2.8369
PELI3 pellino E3 ubiquitin protein ligase family member 3 2.8369
RAB36 RAB36, member RAS oncogene family 2.8369
SELL selectin L 2.8369
F5 coagulation factor V (proaccelerin, labile factor) 2.8369
CNTN3 contactin 3 (plasmacytoma associated) 2.8369
LRRN4CL LRRN4 C-terminal like 2.8369
MGAM maltase-glucoamylase 2.8369
USP2 ubiquitin specific peptidase 2 2.8369
IFT70A intraflagellar transport 70A 2.8369
CIMAP1D CIMAP1 family member D 2.8369
LOC124906010 uncharacterized LOC124906010 2.8369
CCDC197 coiled-coil domain containing 197 2.8369
DEUP1 deuterosome assembly protein 1 2.8369
GBA1 glucosylceramidase beta 1 2.8369
CFAP119 cilia and flagella associated protein 119 2.8369
EPOP elongin BC and polycomb repressive complex 2 associated protein 2.8369
TTLL13 tubulin tyrosine ligase like 13 2.8369
CARMIL2 capping protein regulator and myosin 1 linker 2 2.8369
STAT4 signal transducer and activator of transcription 4 2.8369
BGN biglycan 2.8369
ZNF728 zinc finger protein 728 2.8369
PMP22 peripheral myelin protein 22 2.8369
ASIC3 acid sensing (proton gated) ion channel 3 2.8369
LDHAL6A lactate dehydrogenase A-like 6A 2.8369
IDO2 indoleamine 2,3-dioxygenase 2 2.8369
MEOX1 mesenchyme homeobox 1 2.8369
TNFRSF18 tumor necrosis factor receptor superfamily, member 18 2.8369
TRIM68 tripartite motif containing 68 2.8369
CLDN2 claudin 2 2.8369
CCDC17 coiled-coil domain containing 17 2.8369
KLRF1 killer cell lectin-like receptor subfamily F, member 1 2.8369
PCDHB10 protocadherin beta 10 2.8369
CATSPERQ catsper channel auxiliary subunit theta 2.8369
RNASE4 ribonuclease, RNase A family, 4 2.8369
SLC35D3 solute carrier family 35, member D3 2.8369
ACTL8 actin-like 8 2.8369
OR2AT4 olfactory receptor, family 2, subfamily AT, member 4 2.8369
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 2.8369
GDF9 growth differentiation factor 9 2.8369
PNPLA1 patatin-like phospholipase domain containing 1 2.8369
VCX3A variable charge, X-linked 3A 2.8369
RBM44 RNA binding motif protein 44 2.8369
PLB1 phospholipase B1 2.8369
CDK5R2 cyclin-dependent kinase 5, regulatory subunit 2 (p39) 2.8369
MYOT myotilin 2.8369
LECT2 leukocyte cell-derived chemotaxin 2 2.8369
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G 2.8369
KCNAB3 potassium channel, voltage gated subfamily A regulatory beta subunit 3 2.8369
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1 2.8369
TACSTD2 tumor-associated calcium signal transducer 2 2.8369
CXCL16 chemokine (C-X-C motif) ligand 16 2.8369
PLCXD3 phosphatidylinositol-specific phospholipase C, X domain containing 3 2.8369
ANKRD37 ankyrin repeat domain 37 2.8369
CDC20B cell division cycle 20B 2.8369
EFCAB3 EF-hand calcium binding domain 3 2.8369
PIH1D2 PIH1 domain containing 2 2.8369
BTNL2 butyrophilin-like 2 2.8369
ANKRD63 ankyrin repeat domain 63 2.8369
KLF1 Kruppel-like factor 1 (erythroid) 2.8369
TDRD10 tudor domain containing 10 2.8369
SLC47A2 solute carrier family 47 (multidrug and toxin extrusion), member 2 2.8369
CDH15 cadherin 15, type 1, M-cadherin (myotubule) 2.8369
CBX4 chromobox homolog 4 2.8369
MRAP melanocortin 2 receptor accessory protein 2.8369
TNFRSF25 tumor necrosis factor receptor superfamily, member 25 2.8369
CCDC27 coiled-coil domain containing 27 2.8369
NLRC5 NLR family, CARD domain containing 5 2.8369
RAB40C RAB40C, member RAS oncogene family 2.8369
CCL25 chemokine (C-C motif) ligand 25 2.8369
FZD1 frizzled class receptor 1 2.8369
RUFY4 RUN and FYVE domain containing 4 2.8369
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 2.8369
PRSS57 protease, serine, 57 2.8369
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 2.8369
FCN3 ficolin (collagen/fibrinogen domain containing) 3 2.8369
PLA2G4D phospholipase A2, group IVD (cytosolic) 2.8369
CASS4 Cas scaffolding protein family member 4 2.8369
KRTAP21-2 keratin associated protein 21-2 2.8369
CCDC88B coiled-coil domain containing 88B 2.8369
BMX BMX non-receptor tyrosine kinase 2.8369
BAIAP3 BAI1-associated protein 3 2.8369
EBF2 early B-cell factor 2 2.8369
CSRNP1 cysteine-serine-rich nuclear protein 1 2.8369
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated) 2.8369
PGR progesterone receptor 2.8369
NCR1 natural cytotoxicity triggering receptor 1 2.8369
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3 2.8369
INSL6 insulin-like 6 2.8369
RBPJL recombination signal binding protein for immunoglobulin kappa J region-like 2.8369
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 2.8369
BCL6 B-cell CLL/lymphoma 6 2.8369
FAM151A family with sequence similarity 151, member A 2.8369
UNC5A unc-5 homolog A (C. elegans) 2.8369
TTC29 tetratricopeptide repeat domain 29 2.8369
SLC17A9 solute carrier family 17 (vesicular nucleotide transporter), member 9 2.8369
GJC2 gap junction protein, gamma 2, 47kDa 2.8369
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide 2.8369
ATP10B ATPase, class V, type 10B 2.8369
GPR68 G protein-coupled receptor 68 2.8369
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 2.8369
GPR119 G protein-coupled receptor 119 2.8369
SEC14L4 SEC14-like 4 (S. cerevisiae) 2.8369
ANKS4B ankyrin repeat and sterile alpha motif domain containing 4B 2.8369
LRCOL1 leucine rich colipase-like 1 2.8369
IGF1 insulin-like growth factor 1 (somatomedin C) 2.8369
ZNF843 zinc finger protein 843 2.8369
KLK8 kallikrein-related peptidase 8 2.8369
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal) 2.8369
UTS2R urotensin 2 receptor 2.8369
BEAN1 brain expressed, associated with NEDD4, 1 2.8369
SCNN1B sodium channel, non voltage gated 1 beta subunit 2.8369
FCRLB Fc receptor-like B 2.8369
GDPD4 glycerophosphodiester phosphodiesterase domain containing 4 2.8369
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 2.8369
C5AR1 complement component 5a receptor 1 2.8369
LGALS14 lectin, galactoside-binding, soluble, 14 2.8369
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 2.8369
HIGD1C HIG1 hypoxia inducible domain family, member 1C 2.8369
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 2.8369
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 2.8369
NFE2 nuclear factor, erythroid 2 2.8369
DCST1 DC-STAMP domain containing 1 2.8369
TGM5 transglutaminase 5 2.8369
GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble) 2.8369
OR10G3 olfactory receptor, family 10, subfamily G, member 3 2.8369
ASCL5 achaete-scute family bHLH transcription factor 5 2.8369
SHBG sex hormone-binding globulin 2.8369
SCTR secretin receptor 2.8369
KCNK13 potassium channel, two pore domain subfamily K, member 13 2.8369
NOXRED1 NADP-dependent oxidoreductase domain containing 1 2.8369
MAGEA12 melanoma antigen family A12 2.8369
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1 2.8369
TNS2 tensin 2 2.8369
BTBD18 BTB (POZ) domain containing 18 2.8369
SLITRK4 SLIT and NTRK-like family, member 4 2.8369
LUZP4 leucine zipper protein 4 2.8369
C3ORF18 chromosome 3 open reading frame 18 2.8369
AIPL1 aryl hydrocarbon receptor interacting protein-like 1 2.8369
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal) 2.8369
ARMCX5 armadillo repeat containing, X-linked 5 2.8369
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5 2.8369
PRDM1 PR domain containing 1, with ZNF domain 2.8369
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 2.8369
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled 2.8369
TICAM1 toll-like receptor adaptor molecule 1 2.8369
FGF9 fibroblast growth factor 9 2.8369
GALNT15 polypeptide N-acetylgalactosaminyltransferase 15 2.8369
C12ORF42 chromosome 12 open reading frame 42 2.8369
CIAO1 cytosolic iron-sulfur assembly component 1 2.83542
MASTL microtubule associated serine/threonine kinase-like 2.76519
SLC13A5 solute carrier family 13 (sodium-dependent citrate transporter), member 5 2.75445
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma 2.73832
TOGARAM1 TOG array regulator of axonemal microtubules 1 2.70924
DNAJC27 DnaJ (Hsp40) homolog, subfamily C, member 27 2.68968
CCDC34 coiled-coil domain containing 34 2.65495
LRG1 leucine-rich alpha-2-glycoprotein 1 2.64494
ANGPTL1 angiopoietin-like 1 2.64494
FBL fibrillarin 2.62969
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1 2.60247
TMEM74 transmembrane protein 74 2.60247
SATL1 spermidine/spermine N1-acetyl transferase-like 1 2.60247
NUAK2 NUAK family, SNF1-like kinase, 2 2.60247
MAPRE3 microtubule-associated protein, RP/EB family, member 3 2.59324
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 2.56665
TARBP2 TAR (HIV-1) RNA binding protein 2 2.54818
GGACT gamma-glutamylamine cyclotransferase 2.53032
HMGA1 high mobility group AT-hook 1 2.51799
MLF2 myeloid leukemia factor 2 2.51799
POLR3E polymerase (RNA) III (DNA directed) polypeptide E (80kD) 2.47732
VPS25 vacuolar protein sorting 25 homolog (S. cerevisiae) 2.44892
ICE2 interactor of little elongation complex ELL subunit 2 2.4227
DZIP1 DAZ interacting zinc finger protein 1 2.42034
ENKD1 enkurin domain containing 1 2.40249
IQCH IQ motif containing H 2.40196
RAB11FIP4 RAB11 family interacting protein 4 (class II) 2.39053
SCOC short coiled-coil protein 2.37721
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 2.35093
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 2.3436
ZNHIT3 zinc finger, HIT-type containing 3 2.32516
GRN granulin 2.32429
JKAMP JNK1/MAPK8-associated membrane protein 2.30979
MRPL4 mitochondrial ribosomal protein L4 2.29128
DCAF13 DDB1 and CUL4 associated factor 13 2.29128
WDR18 WD repeat domain 18 2.27888
TMEM167A transmembrane protein 167A 2.25999
RIGI RNA sensor RIG-I 2.2554
CENPN centromere protein N 2.25357
KLHL13 kelch-like family member 13 2.22274
ARHGAP44 Rho GTPase activating protein 44 2.2175
CDYL chromodomain protein, Y-like 2.2175
CENPO centromere protein O 2.2175
PTPN6 protein tyrosine phosphatase, non-receptor type 6 2.16927
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) 2.16918
PMM2 phosphomannomutase 2 2.13956
POMK protein-O-mannose kinase 2.13812
GMFB glia maturation factor, beta 2.13281
TMSB4X thymosin beta 4, X-linked 2.12527
MSANTD4 Myb/SANT-like DNA-binding domain containing 4 with coiled-coils 2.11776
EAPP E2F-associated phosphoprotein 2.11776
HAUS5 HAUS augmin-like complex, subunit 5 2.11515
SLC52A3 solute carrier family 52 (riboflavin transporter), member 3 2.09123
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 2.09123
GID8 GID complex subunit 8 2.08269
MFF mitochondrial fission factor 2.07719
TTC7B tetratricopeptide repeat domain 7B 2.06383
MAGED1 melanoma antigen family D1 2.06317
MGST3 microsomal glutathione S-transferase 3 2.04875
MAP1B microtubule-associated protein 1B 2.00331

decreased expression

Symbol Name Standardized Value
C1QTNF6 C1q and tumor necrosis factor related protein 6 -2.97204
ZNF784 zinc finger protein 784 -2.97204
NLRX1 NLR family member X1 -2.97204
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1 -2.97204
TIGD2 tigger transposable element derived 2 -2.97204
SEC31B SEC31 homolog B (S. cerevisiae) -2.97204
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 -2.90533
UQCRHL ubiquinol-cytochrome c reductase hinge protein-like -2.8369
EFNA3 ephrin-A3 -2.8369
CCDC68 coiled-coil domain containing 68 -2.8369
OXSM 3-oxoacyl-ACP synthase, mitochondrial -2.8369
SLC25A48 solute carrier family 25, member 48 -2.8369
ATG9B autophagy related 9B -2.8369
F12 coagulation factor XII (Hageman factor) -2.8369
GPR158 G protein-coupled receptor 158 -2.8369
MXD3 MAX dimerization protein 3 -2.8369
MT1E metallothionein 1E -2.8369
ACTR5 ARP5 actin-related protein 5 homolog (yeast) -2.8369
NRBP2 nuclear receptor binding protein 2 -2.8369
MYOZ1 myozenin 1 -2.8369
BATF2 basic leucine zipper transcription factor, ATF-like 2 -2.8369
KHK ketohexokinase (fructokinase) -2.8369
CHML choroideremia-like (Rab escort protein 2) -2.8369
CRABP2 cellular retinoic acid binding protein 2 -2.8369
NPIPA2 nuclear pore complex interacting protein family, member A2 -2.8369
KIAA0319 KIAA0319 -2.8369
ZSCAN12 zinc finger and SCAN domain containing 12 -2.8369
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 -2.8369
RHNO1 RAD9-HUS1-RAD1 interacting nuclear orphan 1 -2.8369
ZNF446 zinc finger protein 446 -2.8369
ZNF195 zinc finger protein 195 -2.8369
RIPK4 receptor-interacting serine-threonine kinase 4 -2.8369
DPH7 diphthamide biosynthesis 7 -2.8369
C1ORF74 chromosome 1 open reading frame 74 -2.8369
CFAP210 cilia and flagella associated protein 210 -2.8369
SMIM29 small integral membrane protein 29 -2.8369
SNAP91 synaptosomal-associated protein, 91kDa -2.8369
CFAP73 cilia and flagella associated protein 73 -2.8369
PCCA propionyl CoA carboxylase, alpha polypeptide -2.8369
DLC1 DLC1 Rho GTPase activating protein -2.8369
C6ORF136 chromosome 6 open reading frame 136 -2.8369
TMEM144 transmembrane protein 144 -2.8369
ZFPM2 zinc finger protein, FOG family member 2 -2.8369
PRH1-TAS2R14 PRH1-TAS2R14 readthrough -2.8369
KCTD21 potassium channel tetramerization domain containing 21 -2.8369
SSC5D scavenger receptor cysteine rich family, 5 domains -2.8369
PRRG3 proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane) -2.8369
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 -2.8369
ACP5 acid phosphatase 5, tartrate resistant -2.8369
RNF113A ring finger protein 113A -2.8369
C1QTNF2 C1q and tumor necrosis factor related protein 2 -2.8369
RAMACL RNA guanine-7 methyltransferase activating subunit like -2.8369
ARHGAP32 Rho GTPase activating protein 32 -2.76708
TMEM45A transmembrane protein 45A -2.76599
DNAJB11 DnaJ (Hsp40) homolog, subfamily B, member 11 -2.75455
PLPPR3 phospholipid phosphatase related 3 -2.74491
VAMP7 vesicle-associated membrane protein 7 -2.72622
CCSER1 coiled-coil serine-rich protein 1 -2.72622
VIL1 villin 1 -2.70432
IGFLR1 IGF-like family receptor 1 -2.70432
ZNF615 zinc finger protein 615 -2.70432
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 -2.70432
PLLP plasmolipin -2.70432
NRDE2 NRDE-2, necessary for RNA interference, domain containing -2.67365
RBM15 RNA binding motif protein 15 -2.6408
MAIP1 matrix AAA peptidase interacting protein 1 -2.59765
PEX11A peroxisomal biogenesis factor 11 alpha -2.5718
TLL2 tolloid-like 2 -2.5718
TMEM106A transmembrane protein 106A -2.5718
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2 -2.55271
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa -2.54052
GP6 glycoprotein VI (platelet) -2.5207
CPNE2 copine II -2.5207
FMNL1 formin-like 1 -2.5207
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -2.51799
NAGLU N-acetylglucosaminidase, alpha -2.46223
TPGS1 tubulin polyglutamylase complex subunit 1 -2.4227
LRCH2 leucine-rich repeats and calponin homology (CH) domain containing 2 -2.4227
USP48 ubiquitin specific peptidase 48 -2.42034
ZNRF2 zinc and ring finger 2, E3 ubiquitin protein ligase -2.41734
ARHGEF37 Rho guanine nucleotide exchange factor (GEF) 37 -2.41578
NOL4 nucleolar protein 4 -2.41578
MRPL14 mitochondrial ribosomal protein L14 -2.41578
ANKRD36 ankyrin repeat domain 36 -2.41393
TAF8 TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa -2.4045
TTC13 tetratricopeptide repeat domain 13 -2.39007
CEP112 centrosomal protein 112kDa -2.38654
COG6 component of oligomeric golgi complex 6 -2.382
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae) -2.382
SLC35F6 solute carrier family 35, member F6 -2.35542
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) -2.35542
GINS1 GINS complex subunit 1 (Psf1 homolog) -2.3436
NFE2L1 nuclear factor, erythroid 2-like 1 -2.33067
SLIT2 slit homolog 2 (Drosophila) -2.33067
LMO4 LIM domain only 4 -2.31556
MGMT O-6-methylguanine-DNA methyltransferase -2.31078
ARL10 ADP-ribosylation factor-like 10 -2.29619
CNPPD1 cyclin Pas1/PHO80 domain containing 1 -2.29237
IL7 interleukin 7 -2.29128
ACRV1 acrosomal vesicle protein 1 -2.29128
LYPD3 LY6/PLAUR domain containing 3 -2.29128
DENND1C DENN/MADD domain containing 1C -2.29128
SETD7 SET domain containing (lysine methyltransferase) 7 -2.29128
MVB12B multivesicular body subunit 12B -2.28924
DISP1 dispatched homolog 1 (Drosophila) -2.25616
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -2.23814
LRRC20 leucine rich repeat containing 20 -2.2305
CDC42SE1 CDC42 small effector 1 -2.21091
B3GALT6 UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6 -2.21075
PDP2 pyruvate dehyrogenase phosphatase catalytic subunit 2 -2.21075
ZNF432 zinc finger protein 432 -2.206
STN1 STN1 subunit of CST complex -2.206
SPARCL1 SPARC-like 1 (hevin) -2.206
RHOBTB2 Rho-related BTB domain containing 2 -2.206
HSF5 heat shock transcription factor family member 5 -2.206
FSIP1 fibrous sheath interacting protein 1 -2.206
USP51 ubiquitin specific peptidase 51 -2.206
TCL1B T-cell leukemia/lymphoma 1B -2.206
NME9 NME/NM23 family member 9 -2.206
SLC4A10 solute carrier family 4, sodium bicarbonate transporter, member 10 -2.206
CDHR3 cadherin-related family member 3 -2.19167
MFAP1 microfibrillar-associated protein 1 -2.19106
RPP30 ribonuclease P/MRP 30kDa subunit -2.18993
COX11 COX11 cytochrome c oxidase copper chaperone -2.1886
MBNL1 muscleblind-like splicing regulator 1 -2.16918
UNC93B1 unc-93 homolog B1 (C. elegans) -2.16243
GPR156 G protein-coupled receptor 156 -2.15702
SNX32 sorting nexin 32 -2.15702
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa -2.15327
MRPS28 mitochondrial ribosomal protein S28 -2.143
AGFG1 ArfGAP with FG repeats 1 -2.13281
NEXN nexilin (F actin binding protein) -2.11943
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase -2.11776
FAM114A1 family with sequence similarity 114, member A1 -2.11402
FNBP1L formin binding protein 1-like -2.08816
DRAM2 DNA-damage regulated autophagy modulator 2 -2.08578
PHACTR1 phosphatase and actin regulator 1 -2.08473
AFTPH aftiphilin -2.08473
INTS12 integrator complex subunit 12 -2.07501
GALC galactosylceramidase -2.07501
GLIPR2 GLI pathogenesis-related 2 -2.06857
NFKBID nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta -2.06857
CLU clusterin -2.06383
BCAS3 breast carcinoma amplified sequence 3 -2.05817
ENY2 enhancer of yellow 2 homolog (Drosophila) -2.05277
MMS22L MMS22-like, DNA repair protein -2.04715
KIF11 kinesin family member 11 -2.04615
MICA MHC class I polypeptide-related sequence A -2.0206
PWP1 PWP1 homolog (S. cerevisiae) -2.00428