POLG2 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description polymerase (DNA directed), gamma 2, accessory subunit|This gene encodes the processivity subunit of the mitochondrial DNA polymerase gamma. The encoded protein forms a heterotrimer containing one catalytic subunit and two processivity subunits. This protein enhances DNA binding and promotes processive DNA synthesis. Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions.[provided by RefSeq, Sep 2009] (NCBI Entrez Gene Database, 11232)
External Link http://www.ncbi.nlm.nih.gov/gene/11232
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234 interacting proteins for POLG2 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ALYREF Aly/REF export factor
ASF1A anti-silencing function 1A histone chaperone
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
BANF1 barrier to autointegration factor 1
C14ORF166 chromosome 14 open reading frame 166
C19ORF53 chromosome 19 open reading frame 53
CAMSAP3 calmodulin regulated spectrin-associated protein family, member 3
CAPRIN1 cell cycle associated protein 1
CCAR1 cell division cycle and apoptosis regulator 1
CCDC59 coiled-coil domain containing 59
CCDC86 coiled-coil domain containing 86
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CELF2 CUGBP, Elav-like family member 2
CENPV centromere protein V
CGGBP1 CGG triplet repeat binding protein 1
CIRBP cold inducible RNA binding protein
CNBP CCHC-type zinc finger, nucleic acid binding protein
CRCP CGRP receptor component
CSDE1 cold shock domain containing E1, RNA-binding
CSTF1 cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
CTCF CCCTC-binding factor (zinc finger protein)
DAZAP1 DAZ associated protein 1
DBR1 debranching RNA lariats 1
DDB1 damage-specific DNA binding protein 1, 127kDa
DDB2 damage-specific DNA binding protein 2, 48kDa
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1
DDX18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5
DIS3L2 DIS3 like 3'-5' exoribonuclease 2
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9
DUS3L dihydrouridine synthase 3-like (S. cerevisiae)
EIF4H eukaryotic translation initiation factor 4H
ELAVL1 ELAV like RNA binding protein 1
ELF1 E74-like factor 1 (ets domain transcription factor)
EWSR1 EWS RNA-binding protein 1
EXOSC1 exosome component 1
EXOSC2 exosome component 2
EXOSC4 exosome component 4
EXOSC5 exosome component 5
EXOSC6 exosome component 6
FAM98B family with sequence similarity 98, member B
FBL fibrillarin
FOXK1 forkhead box K1
FOXK2 forkhead box K2
FUBP1 far upstream element (FUSE) binding protein 1
FUBP3 far upstream element (FUSE) binding protein 3
FUS FUS RNA binding protein
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
G3BP2 GTPase activating protein (SH3 domain) binding protein 2
GLUD1 glutamate dehydrogenase 1
GTF2I general transcription factor IIi
H1F0 H1 histone family, member 0
H1FX H1 histone family, member X
HIST1H1B histone cluster 1, H1b
HIST1H1C histone cluster 1, H1c
HIST1H1E histone cluster 1, H1e
HIST1H2BA histone cluster 1, H2ba
HIST1H4F histone cluster 1, H4f
HMGB1 high mobility group box 1
HMGB2 high mobility group box 2
HMGB3 high mobility group box 3
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2)
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
HNRNPK heterogeneous nuclear ribonucleoprotein K
HNRNPL heterogeneous nuclear ribonucleoprotein L
HNRNPM heterogeneous nuclear ribonucleoprotein M
HNRNPR heterogeneous nuclear ribonucleoprotein R
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HP1BP3 heterochromatin protein 1, binding protein 3
HSPA7 heat shock 70kDa protein 7 (HSP70B)
HSPA8 heat shock 70kDa protein 8
HSPA9 heat shock 70kDa protein 9 (mortalin)
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KHSRP KH-type splicing regulatory protein
KIFC1 kinesin family member C1
KLF16 Kruppel-like factor 16
LIG3 ligase III, DNA, ATP-dependent
LIN28B lin-28 homolog B (C. elegans)
LRPPRC leucine-rich pentatricopeptide repeat containing
LYZ lysozyme
MACF1 microtubule-actin crosslinking factor 1
MAP4 microtubule-associated protein 4
MARCKS myristoylated alanine-rich protein kinase C substrate
MARK2 MAP/microtubule affinity-regulating kinase 2
MAZ MYC-associated zinc finger protein (purine-binding transcription factor)
METTL17 methyltransferase like 17
MGME1 mitochondrial genome maintenance exonuclease 1
MGMT O-6-methylguanine-DNA methyltransferase
MPG N-methylpurine-DNA glycosylase
MPO myeloperoxidase
MRPS2 mitochondrial ribosomal protein S2
MRPS23 mitochondrial ribosomal protein S23
MRPS9 mitochondrial ribosomal protein S9
MSH2 mutS homolog 2
MSH3 mutS homolog 3
MSH6 mutS homolog 6
NCL nucleolin
NONO non-POU domain containing, octamer-binding
NOP9 NOP9 nucleolar protein
NRF1 nuclear respiratory factor 1
NUSAP1 nucleolar and spindle associated protein 1
NXF1 nuclear RNA export factor 1
PABPN1 poly(A) binding protein, nuclear 1
PARP1 poly (ADP-ribose) polymerase 1
PARP2 poly (ADP-ribose) polymerase 2
PATL1 protein associated with topoisomerase II homolog 1 (yeast)
PCBP1 poly(rC) binding protein 1
PCBP2 poly(rC) binding protein 2
PEG10 paternally expressed 10
PES1 pescadillo ribosomal biogenesis factor 1
PNKP polynucleotide kinase 3'-phosphatase
POLB polymerase (DNA directed), beta
POLD1 polymerase (DNA directed), delta 1, catalytic subunit
POLG polymerase (DNA directed), gamma
POLR1C polymerase (RNA) I polypeptide C, 30kDa
POLR1D polymerase (RNA) I polypeptide D, 16kDa
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa
POLR2H polymerase (RNA) II (DNA directed) polypeptide H
POLR3A polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
POLR3B polymerase (RNA) III (DNA directed) polypeptide B
POLR3C polymerase (RNA) III (DNA directed) polypeptide C (62kD)
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
POLR3E polymerase (RNA) III (DNA directed) polypeptide E (80kD)
POLR3F polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa
POLR3H polymerase (RNA) III (DNA directed) polypeptide H (22.9kD)
POLRMT polymerase (RNA) mitochondrial (DNA directed)
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PTBP1 polypyrimidine tract binding protein 1
RBM14 RNA binding motif protein 14
RBM3 RNA binding motif (RNP1, RRM) protein 3
RBM39 RNA binding motif protein 39
RBM4 RNA binding motif protein 4
RBMX RNA binding motif protein, X-linked
RECQL RecQ helicase-like
RFC1 replication factor C (activator 1) 1, 145kDa
RFC2 replication factor C (activator 1) 2, 40kDa
RFC3 replication factor C (activator 1) 3, 38kDa
RFC4 replication factor C (activator 1) 4, 37kDa
RFC5 replication factor C (activator 1) 5, 36.5kDa
RNASEH1 ribonuclease H1
RNMT RNA (guanine-7-) methyltransferase
RPA1 replication protein A1, 70kDa
RPA2 replication protein A2, 32kDa
RPA3 replication protein A3, 14kDa
RPL17 ribosomal protein L17
RPL19 ribosomal protein L19
RPL22 ribosomal protein L22
RPL23 ribosomal protein L23
RPL23A ribosomal protein L23a
RPL24 ribosomal protein L24
RPL26 ribosomal protein L26
RPL26L1 ribosomal protein L26-like 1
RPL27A ribosomal protein L27a
RPL31 ribosomal protein L31
RPL32 ribosomal protein L32
RPL35 ribosomal protein L35
RPL36A ribosomal protein L36a
RPL37 ribosomal protein L37
RPL38 ribosomal protein L38
RPL8 ribosomal protein L8
RPS10 ribosomal protein S10
RPS11 ribosomal protein S11
RPS13 ribosomal protein S13
RPS14 ribosomal protein S14
RPS15A ribosomal protein S15a
RPS17 ribosomal protein S17
RPS18 ribosomal protein S18
RPS2 ribosomal protein S2
RPS23 ribosomal protein S23
RPS24 ribosomal protein S24
RPS25 ribosomal protein S25
RPS26 ribosomal protein S26
RPS28 ribosomal protein S28
RPS29 ribosomal protein S29
RPS3 ribosomal protein S3
RPS4X ribosomal protein S4, X-linked
RPS4Y1 ribosomal protein S4, Y-linked 1
RPS6 ribosomal protein S6
RPS7 ribosomal protein S7
RPS8 ribosomal protein S8
RPS9 ribosomal protein S9
RTCB RNA 2',3'-cyclic phosphate and 5'-OH ligase
SCAF11 SR-related CTD-associated factor 11
SF3B2 splicing factor 3b, subunit 2, 145kDa
SFPQ splicing factor proline/glutamine-rich
SLIRP SRA stem-loop interacting RNA binding protein
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
SPATS2L spermatogenesis associated, serine-rich 2-like
SRP14 signal recognition particle 14kDa (homologous Alu RNA binding protein)
SRP9 signal recognition particle 9kDa
SRSF2 serine/arginine-rich splicing factor 2
SRSF3 serine/arginine-rich splicing factor 3
SRSF5 serine/arginine-rich splicing factor 5
SRSF6 serine/arginine-rich splicing factor 6
SRSF7 serine/arginine-rich splicing factor 7
SSB Sjogren syndrome antigen B (autoantigen La)
SSBP1 single-stranded DNA binding protein 1, mitochondrial
SUB1 SUB1 homolog (S. cerevisiae)
SUMO1 small ubiquitin-like modifier 1
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein
TARDBP TAR DNA binding protein
TFAM transcription factor A, mitochondrial
THAP11 THAP domain containing 11
THRAP3 thyroid hormone receptor associated protein 3
TIA1 TIA1 cytotoxic granule-associated RNA binding protein
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1
TMEM214 transmembrane protein 214
TOP1 topoisomerase (DNA) I
TRMT6 tRNA methyltransferase 6
U2AF1 U2 small nuclear RNA auxiliary factor 1
U2AF2 U2 small nuclear RNA auxiliary factor 2
UHRF1 ubiquitin-like with PHD and ring finger domains 1
USP10 ubiquitin specific peptidase 10
XPA xeroderma pigmentosum, complementation group A
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
XRN2 5'-3' exoribonuclease 2
YBX1 Y box binding protein 1
YBX3 Y box binding protein 3
ZC2HC1A zinc finger, C2HC-type containing 1A
ZC3HAV1 zinc finger CCCH-type, antiviral 1
ZFP91 ZFP91 zinc finger protein
ZNF787 zinc finger protein 787