| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa|This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 5430) |
| External Link | https://ncbi.nlm.nih.gov/gene/5430 |
| Similar Terms | |
| Downloads & Tools |
500 genes differentially expressed following the POLR2A gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CA2 | carbonic anhydrase II | 0.014972 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | 0.0147668 |
| TNC | tenascin C | 0.0146424 |
| PRDX2 | peroxiredoxin 2 | 0.013769 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.0135694 |
| LTF | lactotransferrin | 0.0135533 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0133957 |
| CPVL | carboxypeptidase, vitellogenic-like | 0.0124196 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.0121667 |
| TMSB15A | thymosin beta 15a | 0.0117611 |
| SEPP1 | selenoprotein P, plasma, 1 | 0.0110836 |
| OLFM1 | olfactomedin 1 | 0.0108837 |
| HBB | hemoglobin, beta | 0.010853 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | 0.0106751 |
| BEX1 | brain expressed, X-linked 1 | 0.0106669 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | 0.0106558 |
| TFF3 | trefoil factor 3 (intestinal) | 0.0105658 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.0102979 |
| RPA3 | replication protein A3, 14kDa | 0.0102871 |
| MAP7 | microtubule-associated protein 7 | 0.010181 |
| MMP9 | matrix metallopeptidase 9 | 0.010155 |
| HP | haptoglobin | 0.00986943 |
| DHFR | dihydrofolate reductase | 0.0098599 |
| GLTP | glycolipid transfer protein | 0.00976091 |
| SDC2 | syndecan 2 | 0.00975076 |
| DUT | deoxyuridine triphosphatase | 0.00972985 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | 0.00972131 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | 0.00963697 |
| GANAB | glucosidase, alpha; neutral AB | 0.00954377 |
| ARG1 | arginase 1 | 0.00953632 |
| ANXA6 | annexin A6 | 0.00949362 |
| LMNB1 | lamin B1 | 0.00946349 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | 0.00941971 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | 0.00932302 |
| AOX1 | aldehyde oxidase 1 | 0.00932194 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | 0.0092846 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.00921368 |
| FGFR3 | fibroblast growth factor receptor 3 | 0.00909613 |
| BIRC5 | baculoviral IAP repeat containing 5 | 0.00897283 |
| GLUL | glutamate-ammonia ligase | 0.00892014 |
| ICMT | isoprenylcysteine carboxyl methyltransferase | 0.00884811 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.00880175 |
| TFDP1 | transcription factor Dp-1 | 0.00877808 |
| ADH1C | alcohol dehydrogenase 1C (class I), gamma polypeptide | 0.00874782 |
| SORD | sorbitol dehydrogenase | 0.00873461 |
| PRC1 | protein regulator of cytokinesis 1 | 0.00871215 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.00867873 |
| HOXC6 | homeobox C6 | 0.00854911 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | 0.00852885 |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) | 0.00849731 |
| INSM1 | insulinoma-associated 1 | 0.00841793 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | 0.00841049 |
| CALD1 | caldesmon 1 | 0.00840582 |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 | 0.00838732 |
| NRN1 | neuritin 1 | 0.00836491 |
| FADS1 | fatty acid desaturase 1 | 0.00835887 |
| PRKD3 | protein kinase D3 | 0.00828786 |
| TYRP1 | tyrosinase-related protein 1 | 0.0082254 |
| HSD17B6 | hydroxysteroid (17-beta) dehydrogenase 6 | 0.00812237 |
| TMX1 | thioredoxin-related transmembrane protein 1 | 0.00799898 |
| INSIG1 | insulin induced gene 1 | 0.00795713 |
| CYP2E1 | cytochrome P450, family 2, subfamily E, polypeptide 1 | 0.00792726 |
| GCK | glucokinase (hexokinase 4) | 0.00791016 |
| LIG1 | ligase I, DNA, ATP-dependent | 0.00790232 |
| ESR1 | estrogen receptor 1 | 0.00789104 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.00787382 |
| PCNA | proliferating cell nuclear antigen | 0.00786804 |
| PXMP2 | peroxisomal membrane protein 2, 22kDa | 0.00782962 |
| CDCA4 | cell division cycle associated 4 | 0.00778819 |
| PSRC1 | proline/serine-rich coiled-coil 1 | 0.00777613 |
| CRIP2 | cysteine-rich protein 2 | 0.00775575 |
| MMP12 | matrix metallopeptidase 12 | 0.00774396 |
| FCGBP | Fc fragment of IgG binding protein | 0.00773844 |
| CNR1 | cannabinoid receptor 1 (brain) | 0.00773257 |
| TRMT5 | tRNA methyltransferase 5 | 0.0077189 |
| ILK | integrin-linked kinase | 0.007716 |
| SLC44A4 | solute carrier family 44, member 4 | 0.00771126 |
| THYN1 | thymocyte nuclear protein 1 | 0.00762165 |
| FGL2 | fibrinogen-like 2 | 0.00762084 |
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4A | 0.00761208 |
| PRMT1 | protein arginine methyltransferase 1 | 0.00759905 |
| ACTN1 | actinin, alpha 1 | 0.00758767 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | 0.00758295 |
| ASF1B | anti-silencing function 1B histone chaperone | 0.00757296 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.00755693 |
| CEACAM8 | carcinoembryonic antigen-related cell adhesion molecule 8 | 0.00755565 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.00752033 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | 0.00751217 |
| LYZ | lysozyme | 0.00746964 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 | 0.00746069 |
| FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide | 0.00745588 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.00741075 |
| ADAM28 | ADAM metallopeptidase domain 28 | 0.00740981 |
| MPZL2 | myelin protein zero-like 2 | 0.00738103 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.00737708 |
| SRSF1 | serine/arginine-rich splicing factor 1 | 0.00735739 |
| KIF15 | kinesin family member 15 | 0.00731906 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | 0.00730404 |
| EXPH5 | exophilin 5 | 0.00725217 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 | 0.00723296 |
| CCNE2 | cyclin E2 | 0.0072237 |
| PLSCR4 | phospholipid scramblase 4 | 0.00720475 |
| ACKR3 | atypical chemokine receptor 3 | 0.00719546 |
| CYP4F3 | cytochrome P450, family 4, subfamily F, polypeptide 3 | 0.0071948 |
| ACYP2 | acylphosphatase 2, muscle type | 0.00717707 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.00716853 |
| RRM1 | ribonucleotide reductase M1 | 0.00715929 |
| TRAPPC3 | trafficking protein particle complex 3 | 0.00715472 |
| C7 | complement component 7 | 0.00713502 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | 0.00713489 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.00710914 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | 0.00710866 |
| PCLAF | PCNA clamp associated factor | 0.00710201 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.00709377 |
| THAP12 | THAP domain containing 12 | 0.00708478 |
| PAH | phenylalanine hydroxylase | 0.00708223 |
| CP | ceruloplasmin (ferroxidase) | 0.00707759 |
| ANPEP | alanyl (membrane) aminopeptidase | 0.00707003 |
| COPS7A | COP9 signalosome subunit 7A | 0.00706924 |
| KIF1B | kinesin family member 1B | 0.00704534 |
| ALDOC | aldolase C, fructose-bisphosphate | 0.00703996 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | 0.00701994 |
| SOX11 | SRY (sex determining region Y)-box 11 | 0.00701078 |
| RMI1 | RecQ mediated genome instability 1 | 0.00696767 |
| CD300A | CD300a molecule | 0.00696689 |
| ATG5 | autophagy related 5 | 0.00695705 |
| DPYD | dihydropyrimidine dehydrogenase | 0.00691451 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | 0.00691329 |
| AMD1 | adenosylmethionine decarboxylase 1 | 0.0069126 |
| NDRG2 | NDRG family member 2 | 0.00690969 |
| PDZK1 | PDZ domain containing 1 | 0.00689048 |
| MIS18A | MIS18 kinetochore protein A | 0.00688684 |
| TACC1 | transforming, acidic coiled-coil containing protein 1 | 0.0068619 |
| PLPBP | pyridoxal phosphate binding protein | 0.00685674 |
| PRPF19 | pre-mRNA processing factor 19 | 0.00685111 |
| MTHFD1 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase | 0.00685021 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.00684369 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 0.00683416 |
| LBR | lamin B receptor | 0.00683117 |
| MREG | melanoregulin | 0.00683066 |
| GAS1 | growth arrest-specific 1 | 0.00681166 |
| FMO3 | flavin containing monooxygenase 3 | 0.00680278 |
| MNDA | myeloid cell nuclear differentiation antigen | 0.00679722 |
| TXLNA | taxilin alpha | 0.00679594 |
| B3GNT1 | 0.00679537 | |
| SELL | selectin L | 0.00679309 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.00676053 |
| TFF1 | trefoil factor 1 | 0.006751 |
| DHCR7 | 7-dehydrocholesterol reductase | 0.00674454 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.00673589 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.00672283 |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) | 0.00669075 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | 0.00666662 |
| SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 | 0.00666202 |
| SCAMP1 | secretory carrier membrane protein 1 | 0.00665464 |
| WFDC2 | WAP four-disulfide core domain 2 | 0.00665073 |
| DEFA4 | defensin, alpha 4, corticostatin | 0.00663922 |
| FAM171A1 | family with sequence similarity 171, member A1 | 0.00663659 |
| PSMC3 | proteasome (prosome, macropain) 26S subunit, ATPase, 3 | 0.00662731 |
| PITX1 | paired-like homeodomain 1 | 0.00662705 |
| IGSF6 | immunoglobulin superfamily, member 6 | 0.00660563 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 0.00660355 |
| GET1 | guided entry of tail-anchored proteins factor 1 | 0.00660027 |
| H2AZ1 | H2A.Z variant histone 1 | 0.00659696 |
| RAPSN | receptor-associated protein of the synapse | 0.00659288 |
| CCL19 | chemokine (C-C motif) ligand 19 | 0.00659156 |
| EFHC2 | EF-hand domain (C-terminal) containing 2 | 0.00656464 |
| RAB27A | RAB27A, member RAS oncogene family | 0.00656281 |
| GUCY1B3 | guanylate cyclase 1, soluble, beta 3 | 0.00655244 |
| NNMT | nicotinamide N-methyltransferase | 0.00655209 |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase | 0.0065435 |
| FEN1 | flap structure-specific endonuclease 1 | 0.0065301 |
| CLCA4 | chloride channel accessory 4 | 0.0065012 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | 0.00649751 |
| NPL | N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) | 0.00647776 |
| MCM2 | minichromosome maintenance complex component 2 | 0.00646366 |
| HMGN5 | high mobility group nucleosome binding domain 5 | 0.00644905 |
| ZWINT | ZW10 interacting kinetochore protein | 0.00644399 |
| OIP5 | Opa interacting protein 5 | 0.0064216 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | 0.00641202 |
| SELENOW | selenoprotein W | 0.00641093 |
| CD164 | CD164 molecule, sialomucin | 0.00639811 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | 0.00639492 |
| MMP8 | matrix metallopeptidase 8 | 0.00638439 |
| MSMO1 | methylsterol monooxygenase 1 | 0.00636478 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | 0.00635813 |
| SIVA1 | SIVA1, apoptosis-inducing factor | 0.00635154 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.00633006 |
| DNASE1L3 | deoxyribonuclease I-like 3 | 0.00632955 |
| GCH1 | GTP cyclohydrolase 1 | 0.00630624 |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase | 0.00630502 |
| NPM3 | nucleophosmin/nucleoplasmin 3 | 0.00629901 |
| HPF1 | histone PARylation factor 1 | 0.00626684 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | 0.00625023 |
| ATP1A1 | ATPase, Na+/K+ transporting, alpha 1 polypeptide | 0.00624889 |
| TMCO3 | transmembrane and coiled-coil domains 3 | 0.00623472 |
| TOX3 | TOX high mobility group box family member 3 | 0.00623388 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.00622157 |
| CCNA2 | cyclin A2 | 0.00621361 |
| FABP7 | fatty acid binding protein 7, brain | 0.00621136 |
| ZNF274 | zinc finger protein 274 | 0.00620474 |
| CD59 | CD59 molecule, complement regulatory protein | 0.00619937 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.0061976 |
| PURA | purine-rich element binding protein A | 0.00619117 |
| GCA | grancalcin, EF-hand calcium binding protein | 0.00618163 |
| IQGAP2 | IQ motif containing GTPase activating protein 2 | 0.00615961 |
| KCNE4 | potassium channel, voltage gated subfamily E regulatory beta subunit 4 | 0.00615606 |
| NR3C2 | nuclear receptor subfamily 3, group C, member 2 | 0.0061438 |
| NFASC | neurofascin | 0.00613229 |
| ATF1 | activating transcription factor 1 | 0.00613044 |
| LRIF1 | ligand dependent nuclear receptor interacting factor 1 | 0.00612679 |
| HMGB2 | high mobility group box 2 | 0.00612575 |
| RDX | radixin | 0.00612206 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 | 0.00612196 |
| RAB25 | RAB25, member RAS oncogene family | 0.00612165 |
| HS3ST1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 1 | 0.00611289 |
| ZW10 | zw10 kinetochore protein | 0.00611104 |
| MCF2L | MCF.2 cell line derived transforming sequence-like | 0.00610907 |
| SELENOT | selenoprotein T | 0.0061048 |
| ACAT2 | acetyl-CoA acetyltransferase 2 | 0.00609994 |
| MSX1 | msh homeobox 1 | 0.0060973 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.00605533 |
| VBP1 | von Hippel-Lindau binding protein 1 | 0.0060546 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A | 0.00605269 |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 | 0.00604387 |
| PPA2 | pyrophosphatase (inorganic) 2 | 0.00603407 |
| EDN3 | endothelin 3 | 0.00602705 |
| RPRD1A | regulation of nuclear pre-mRNA domain containing 1A | 0.00602154 |
| ADAMDEC1 | ADAM-like, decysin 1 | 0.00601931 |
| CLIC2 | chloride intracellular channel 2 | 0.00601782 |
| TMEM109 | transmembrane protein 109 | 0.00601538 |
| LSM3 | LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00599367 |
| ELP5 | elongator acetyltransferase complex subunit 5 | 0.00598243 |
| OAZ2 | ornithine decarboxylase antizyme 2 | 0.0059804 |
| PRMT2 | protein arginine methyltransferase 2 | 0.00596497 |
| CPQ | carboxypeptidase Q | 0.00595747 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.00595407 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 | 0.00594779 |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 | 0.00594573 |
| NDN | necdin, melanoma antigen (MAGE) family member | 0.00594226 |
| PRRX1 | paired related homeobox 1 | 0.00592757 |
| GRHL2 | grainyhead-like 2 (Drosophila) | 0.00592335 |
| CD200 | CD200 molecule | 0.00592254 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.00591676 |
| HDAC6 | histone deacetylase 6 | 0.00590859 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | 0.005908 |
| BCL2A1 | BCL2-related protein A1 | 0.00589757 |
| PLG | plasminogen | 0.00589729 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | 0.00589424 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 | 0.00588805 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA1A | heat shock 70kDa protein 1A | -0.0222801 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | -0.0188538 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0184556 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | -0.0167045 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0160722 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0159825 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0158054 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0152361 |
| MX1 | MX dynamin-like GTPase 1 | -0.0143124 |
| KRT14 | keratin 14, type I | -0.0141963 |
| APOD | apolipoprotein D | -0.0133321 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0132269 |
| IER5 | immediate early response 5 | -0.0132092 |
| SMAD3 | SMAD family member 3 | -0.0131764 |
| PLAAT3 | phospholipase A and acyltransferase 3 | -0.0131088 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.0129525 |
| BIK | BCL2-interacting killer (apoptosis-inducing) | -0.0128945 |
| PEG10 | paternally expressed 10 | -0.0128768 |
| CRYAB | crystallin, alpha B | -0.0127655 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0126197 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0126029 |
| LCN2 | lipocalin 2 | -0.012447 |
| ASS1 | argininosuccinate synthase 1 | -0.0122478 |
| ANXA1 | annexin A1 | -0.0121477 |
| MYOF | myoferlin | -0.0118797 |
| SIRT3 | sirtuin 3 | -0.0115778 |
| ECM1 | extracellular matrix protein 1 | -0.0114985 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0113808 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.011199 |
| UPP1 | uridine phosphorylase 1 | -0.0111585 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | -0.0110624 |
| KLK11 | kallikrein-related peptidase 11 | -0.0110467 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.0109725 |
| JCHAIN | joining chain of multimeric IgA and IgM | -0.0108735 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0108499 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0107904 |
| TRIM22 | tripartite motif containing 22 | -0.0106643 |
| MET | MET proto-oncogene, receptor tyrosine kinase | -0.0106562 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') | -0.0106137 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | -0.0103723 |
| IGFBP6 | insulin-like growth factor binding protein 6 | -0.0103663 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | -0.0103496 |
| S100A10 | S100 calcium binding protein A10 | -0.01032 |
| KLK10 | kallikrein-related peptidase 10 | -0.0102977 |
| PLK2 | polo-like kinase 2 | -0.0101117 |
| HIST1H2AC | histone cluster 1, H2ac | -0.0101072 |
| IFI44L | interferon-induced protein 44-like | -0.0100936 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | -0.0100742 |
| CFD | complement factor D (adipsin) | -0.0100576 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.010048 |
| PLXNB2 | plexin B2 | -0.00999278 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.00987875 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.00982593 |
| BMP2 | bone morphogenetic protein 2 | -0.00981031 |
| PTN | pleiotrophin | -0.00976827 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.00973809 |
| PRSS23 | protease, serine, 23 | -0.00973586 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | -0.00971243 |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 | -0.00962009 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | -0.00954327 |
| LAMB1 | laminin, beta 1 | -0.00953011 |
| STC2 | stanniocalcin 2 | -0.00952064 |
| SPATA20 | spermatogenesis associated 20 | -0.00942048 |
| CKM | creatine kinase, muscle | -0.00941589 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.00941186 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | -0.00934691 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | -0.00934579 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | -0.00928947 |
| ATF3 | activating transcription factor 3 | -0.00926892 |
| VAMP8 | vesicle-associated membrane protein 8 | -0.00921016 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0092088 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 | -0.00920234 |
| IRF7 | interferon regulatory factor 7 | -0.00918917 |
| AGRN | agrin | -0.00918043 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.00916163 |
| IL1B | interleukin 1, beta | -0.00913718 |
| XIC | X chromosome inactivation center | -0.00910189 |
| S100A11 | S100 calcium binding protein A11 | -0.00909785 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | -0.00908919 |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | -0.00902991 |
| SQSTM1 | sequestosome 1 | -0.00901787 |
| FKBP11 | FK506 binding protein 11, 19 kDa | -0.00901097 |
| IFI35 | interferon-induced protein 35 | -0.0089758 |
| OFD1 | oral-facial-digital syndrome 1 | -0.00893851 |
| RBM47 | RNA binding motif protein 47 | -0.00893248 |
| MZB1 | marginal zone B and B1 cell-specific protein | -0.00887846 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.00882537 |
| SFRP4 | secreted frizzled-related protein 4 | -0.00875384 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 | -0.00871943 |
| ANXA4 | annexin A4 | -0.00871845 |
| AMOTL2 | angiomotin like 2 | -0.00869168 |
| COL5A2 | collagen, type V, alpha 2 | -0.00861667 |
| TYMP | thymidine phosphorylase | -0.00859059 |
| YBX3 | Y box binding protein 3 | -0.00855417 |
| MVP | major vault protein | -0.00853498 |
| CARD10 | caspase recruitment domain family, member 10 | -0.00845707 |
| HIST1H2BK | histone cluster 1, H2bk | -0.00833853 |
| HSPB8 | heat shock 22kDa protein 8 | -0.00832949 |
| CCN2 | cellular communication network factor 2 | -0.00830208 |
| OSR2 | odd-skipped related transciption factor 2 | -0.00829378 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.00824573 |
| ITGAV | integrin, alpha V | -0.00823441 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | -0.00819161 |
| HK1 | hexokinase 1 | -0.00818275 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -0.00817418 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.00809044 |
| PDZK1IP1 | PDZK1 interacting protein 1 | -0.00808662 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase | -0.00806445 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.00805945 |
| IL32 | interleukin 32 | -0.00796871 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.0079383 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.00791841 |
| CFB | complement factor B | -0.00790314 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.00786855 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.00781872 |
| SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) | -0.0076857 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.00767688 |
| LAMC2 | laminin, gamma 2 | -0.00764526 |
| AMDHD2 | amidohydrolase domain containing 2 | -0.00755091 |
| TSPAN15 | tetraspanin 15 | -0.0075381 |
| TRIB3 | tribbles pseudokinase 3 | -0.00751938 |
| BCL3 | B-cell CLL/lymphoma 3 | -0.00748763 |
| RTN2 | reticulon 2 | -0.00747537 |
| EGR1 | early growth response 1 | -0.00745427 |
| VGLL4 | vestigial-like family member 4 | -0.00744376 |
| TTC39A | tetratricopeptide repeat domain 39A | -0.00744107 |
| RABAC1 | Rab acceptor 1 (prenylated) | -0.00743569 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.0074213 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | -0.00741932 |
| RPS27L | ribosomal protein S27-like | -0.00741751 |
| TNNC2 | troponin C type 2 (fast) | -0.00737489 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | -0.00736704 |
| IFI44 | interferon-induced protein 44 | -0.00736453 |
| TAX1BP3 | Tax1 (human T-cell leukemia virus type I) binding protein 3 | -0.00736045 |
| NEU1 | sialidase 1 (lysosomal sialidase) | -0.00735648 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0073538 |
| PHLDA3 | pleckstrin homology-like domain, family A, member 3 | -0.00731954 |
| LPIN1 | lipin 1 | -0.00727531 |
| LAMB3 | laminin, beta 3 | -0.00727258 |
| FXYD5 | FXYD domain containing ion transport regulator 5 | -0.00726722 |
| MINK1 | misshapen-like kinase 1 | -0.00720172 |
| JUP | junction plakoglobin | -0.00719924 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | -0.00719417 |
| GPRC5B | G protein-coupled receptor, class C, group 5, member B | -0.00717937 |
| SYNGR3 | synaptogyrin 3 | -0.00714691 |
| IPO13 | importin 13 | -0.0071357 |
| ABHD4 | abhydrolase domain containing 4 | -0.00712499 |
| FN1 | fibronectin 1 | -0.00712355 |
| KRT18 | keratin 18, type I | -0.00712049 |
| SP100 | SP100 nuclear antigen | -0.0071128 |
| POLDIP2 | polymerase (DNA-directed), delta interacting protein 2 | -0.00711153 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.00710072 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -0.00705998 |
| TNNC1 | troponin C type 1 (slow) | -0.007055 |
| TNNT1 | troponin T type 1 (skeletal, slow) | -0.00704593 |
| GDF15 | growth differentiation factor 15 | -0.00704172 |
| RAB9A | RAB9A, member RAS oncogene family | -0.00703096 |
| COL16A1 | collagen, type XVI, alpha 1 | -0.00702378 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) | -0.00700971 |
| SGCE | sarcoglycan, epsilon | -0.00700871 |
| FHL2 | four and a half LIM domains 2 | -0.00700598 |
| RFTN1 | raftlin, lipid raft linker 1 | -0.00696106 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | -0.00695218 |
| HIST1H2BD | histone cluster 1, H2bd | -0.00693101 |
| RHBDF1 | rhomboid 5 homolog 1 (Drosophila) | -0.00688547 |
| GRK5 | G protein-coupled receptor kinase 5 | -0.0068838 |
| CLCN4 | chloride channel, voltage-sensitive 4 | -0.00688338 |
| GRN | granulin | -0.00685281 |
| YPEL5 | yippee-like 5 (Drosophila) | -0.00685262 |
| FAM110B | family with sequence similarity 110, member B | -0.0068162 |
| KLHL24 | kelch-like family member 24 | -0.00680527 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | -0.00680459 |
| FBLN1 | fibulin 1 | -0.00679842 |
| CALB1 | calbindin 1, 28kDa | -0.00679827 |
| ZNF706 | zinc finger protein 706 | -0.00679317 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 | -0.00679271 |
| USP18 | ubiquitin specific peptidase 18 | -0.00678902 |
| AVPI1 | arginine vasopressin-induced 1 | -0.00677209 |
| TGFA | transforming growth factor, alpha | -0.00676337 |
| SLC16A5 | solute carrier family 16 (monocarboxylate transporter), member 5 | -0.00674043 |
| EFNA1 | ephrin-A1 | -0.00672126 |
| HGD | homogentisate 1,2-dioxygenase | -0.00671641 |
| IRF9 | interferon regulatory factor 9 | -0.0066844 |
| NPC1 | Niemann-Pick disease, type C1 | -0.00666647 |
| ADIRF | adipogenesis regulatory factor | -0.00665901 |
| SRPX | sushi-repeat containing protein, X-linked | -0.00664727 |
| NADSYN1 | NAD synthetase 1 | -0.00663272 |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 | -0.00662422 |
| FOXF2 | forkhead box F2 | -0.0066111 |
| LIF | leukemia inhibitory factor | -0.00659513 |
| MYBPC1 | myosin binding protein C, slow type | -0.00659315 |
| NVL | nuclear VCP-like | -0.00657058 |
| EPS8L2 | EPS8-like 2 | -0.00656491 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | -0.00655336 |
| OSBPL9 | oxysterol binding protein-like 9 | -0.0065407 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 | -0.00652042 |
| MID1 | midline 1 | -0.00651777 |
| PLOD3 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 | -0.00650514 |
| RIN2 | Ras and Rab interactor 2 | -0.0064839 |
| OLFML2A | olfactomedin-like 2A | -0.00646043 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 | -0.00645844 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.00645759 |
| GGT1 | gamma-glutamyltransferase 1 | -0.00643582 |
| TGIF1 | TGFB-induced factor homeobox 1 | -0.0064349 |
| ATF4 | activating transcription factor 4 | -0.00643354 |
| RGS3 | regulator of G-protein signaling 3 | -0.00642301 |
| IGF1R | insulin-like growth factor 1 receptor | -0.00641435 |
| IGF2R | insulin-like growth factor 2 receptor | -0.00641332 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | -0.00640855 |
| SLC3A2 | solute carrier family 3 (amino acid transporter heavy chain), member 2 | -0.00640498 |
| SCPEP1 | serine carboxypeptidase 1 | -0.00637713 |
| MATN2 | matrilin 2 | -0.00637585 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) | -0.00636541 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.00635208 |
| COL14A1 | collagen, type XIV, alpha 1 | -0.00634713 |
| GATA6 | GATA binding protein 6 | -0.00634632 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 | -0.00633897 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.00626815 |
| BIN1 | bridging integrator 1 | -0.00626734 |
| RRAS | related RAS viral (r-ras) oncogene homolog | -0.00626645 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.00625646 |
| ZBED2 | zinc finger, BED-type containing 2 | -0.00624682 |
| DSP | desmoplakin | -0.00624544 |
| HMOX1 | heme oxygenase 1 | -0.00622679 |
| DIPK1A | divergent protein kinase domain 1A | -0.00622493 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.00622184 |
| GRINA | glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) | -0.00621846 |
| CTSL | cathepsin L | -0.00621579 |
| MXRA7 | matrix-remodelling associated 7 | -0.00621464 |
| NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 | -0.00620668 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 | -0.00620617 |
| AREG | amphiregulin | -0.00618779 |
| NID2 | nidogen 2 (osteonidogen) | -0.00616199 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.00615432 |
| CD70 | CD70 molecule | -0.00612858 |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 | -0.00612151 |
| WDR45 | WD repeat domain 45 | -0.00611601 |
| KLHL41 | kelch-like family member 41 | -0.00610165 |
| PFKM | phosphofructokinase, muscle | -0.00609375 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.00608895 |
| DUSP6 | dual specificity phosphatase 6 | -0.00607008 |
| BLNK | B-cell linker | -0.00606969 |
| OGN | osteoglycin | -0.00606954 |
| RGS20 | regulator of G-protein signaling 20 | -0.00606895 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.00604764 |
| ITSN2 | intersectin 2 | -0.0060452 |
| IGLL1 | immunoglobulin lambda-like polypeptide 1 | -0.00604313 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.00603615 |
| GOLGA8H | golgin A8 family, member H | -0.00602039 |
| ANKRD28 | ankyrin repeat domain 28 | -0.00601589 |
