POLR2A Gene Set

Dataset NURSA Protein-Protein Interactions
Category proteomics
Type interacting protein
Description polymerase (RNA) II (DNA directed) polypeptide A, 220kDa|This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 5430)
External Link http://www.ncbi.nlm.nih.gov/gene/5430
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3 interacting proteins for POLR2A from the NURSA Protein-Protein Interactions dataset.

Symbol Name Standardized Value
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa 1.21856
BPTF bromodomain PHD finger transcription factor 0.127312
RECQL5 RecQ protein-like 5 0.020551