POMC Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description proopiomelanocortin|This gene encodes a polypeptide hormone precursor that undergoes extensive, tissue-specific, post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases. There are eight potential cleavage sites within the polypeptide precursor and, depending on tissue type and the available convertases, processing may yield as many as ten biologically active peptides involved in diverse cellular functions. The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used; adrenocorticotrophin, essential for normal steroidogenesis and the maintenance of normal adrenal weight, and lipotropin beta are the major end products. In other tissues, including the hypothalamus, placenta, and epithelium, all cleavage sites may be used, giving rise to peptides with roles in pain and energy homeostasis, melanocyte stimulation, and immune modulation. These include several distinct melanotropins, lipotropins, and endorphins that are contained within the adrenocorticotrophin and beta-lipotropin peptides. The antimicrobial melanotropin alpha peptide exhibits antibacterial and antifungal activity. Mutations in this gene have been associated with early onset obesity, adrenal insufficiency, and red hair pigmentation. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Nov 2014] (NCBI Entrez Gene Database, 5443)
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Genes

353 genes differentially expressed following the POMC gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
KASH5 KASH domain containing 5 3.35844
OR52A5 olfactory receptor, family 52, subfamily A, member 5 3.35844
OPN5 opsin 5 3.35844
C11ORF96 chromosome 11 open reading frame 96 3.35844
LOC124901872 uncharacterized LOC124901872 3.35844
BHLHE40 basic helix-loop-helix family, member e40 3.35844
CDH10 cadherin 10, type 2 (T2-cadherin) 3.35844
SRPK3 SRSF protein kinase 3 3.35844
PCDH19 protocadherin 19 3.35844
LY6K lymphocyte antigen 6 complex, locus K 3.35844
DNAAF1 dynein, axonemal, assembly factor 1 3.35844
CIITA class II, major histocompatibility complex, transactivator 3.35844
FOXP3 forkhead box P3 3.35844
OR2A5 olfactory receptor, family 2, subfamily A, member 5 3.35844
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8 3.35844
SMIM36 small integral membrane protein 36 3.35844
CCDC198 coiled-coil domain containing 198 3.35844
SPATA31G1 SPATA31 subfamily G member 1 3.35844
NPAP1 nuclear pore associated protein 1 3.35844
SNAI2 snail family zinc finger 2 3.35844
SCN2B sodium channel, voltage gated, type II beta subunit 3.35844
SEMG1 semenogelin I 3.35844
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 3.35844
ATP13A5 ATPase type 13A5 3.35844
ATP13A4 ATPase type 13A4 3.35844
CARD16 caspase recruitment domain family, member 16 3.34934
BSND barttin CLCNK-type chloride channel accessory beta subunit 3.34934
GJB2 gap junction protein, beta 2, 26kDa 3.34934
UCN urocortin 3.34934
TMEM191B transmembrane protein 191B 3.34934
SLC26A1 solute carrier family 26 (anion exchanger), member 1 3.34934
PROKR1 prokineticin receptor 1 3.34934
OR10A3 olfactory receptor, family 10, subfamily A, member 3 3.34934
AFM afamin 3.34934
OR10A2 olfactory receptor, family 10, subfamily A, member 2 3.34934
SLC26A4 solute carrier family 26 (anion exchanger), member 4 3.34934
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa 3.34934
EPPIN epididymal peptidase inhibitor 3.34934
RFPL3 ret finger protein-like 3 3.34934
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5 3.34934
PSCA prostate stem cell antigen 3.34934
MEIKIN meiotic kinetochore factor 3.34934
TMCO5A transmembrane and coiled-coil domains 5A 3.34934
ATOH8 atonal homolog 8 (Drosophila) 3.34934
MYO16 myosin XVI 3.34934
GALR2 galanin receptor 2 3.34934
ETV2 ets variant 2 3.34934
CDRT15 CMT1A duplicated region transcript 15 3.34934
NMUR2 neuromedin U receptor 2 3.34934
RGPD3 RANBP2-like and GRIP domain containing 3 3.34934
OR2AJ1 olfactory receptor, family 2, subfamily AJ, member 1 3.34934
GNAT1 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 3.34934
DMRTC1B DMRT-like family C1B 3.34934
XCL1 chemokine (C motif) ligand 1 3.34934
ASB17 ankyrin repeat and SOCS box containing 17 3.34934
ASPG asparaginase 3.34934
GIMAP4 GTPase, IMAP family member 4 3.34934
REN renin 3.34934
NOTUM notum pectinacetylesterase homolog (Drosophila) 3.34934
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa 3.34934
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa 3.34934
EVPL envoplakin 3.34934
LOC124906892 uncharacterized LOC124906892 3.34934
CES4A carboxylesterase 4A 3.34934
ZAR1 zygote arrest 1 3.34934
MCHR2 melanin-concentrating hormone receptor 2 3.34934
ST6GALNAC1 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 3.34934
CCER2 coiled-coil glutamate-rich protein 2 3.34934
ACER1 alkaline ceramidase 1 3.34934
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G 3.34934
CYLC2 cylicin, basic protein of sperm head cytoskeleton 2 3.34934
FOXC2 forkhead box C2 3.34934
AJM1 apical junction component 1 homolog 3.34934
NHLRC1 NHL repeat containing E3 ubiquitin protein ligase 1 3.34934
H2BC3 H2B clustered histone 3 3.34934
LY6S lymphocyte antigen 6 family member S 3.34934
PRR20G proline rich 20G 3.34934
C8ORF90 chromosome 8 open reading frame 90 3.34934
SPAAR small regulatory polypeptide of amino acid response 3.34934
SMIM31 small integral membrane protein 31 3.34934
LY6L lymphocyte antigen 6 family member L 3.34934
TEX13D TEX13 family member D 3.34934
DNAAF6 dynein axonemal assembly factor 6 3.34934
TMEM273 transmembrane protein 273 3.34934
OR52E5 olfactory receptor, family 52, subfamily E, member 5 3.34934
KHDC1L KH homology domain containing 1-like 3.34934
NKX2-6 NK2 homeobox 6 3.34934
IL12RB1 interleukin 12 receptor, beta 1 3.34934
LIPF lipase, gastric 3.34934
PLD4 phospholipase D family, member 4 3.34934
ELAVL4 ELAV like neuron-specific RNA binding protein 4 3.34934
CPED1 cadherin-like and PC-esterase domain containing 1 3.34934
CYP26C1 cytochrome P450, family 26, subfamily C, polypeptide 1 3.34934
MS4A6E membrane-spanning 4-domains, subfamily A, member 6E 3.34934
NDRG1 N-myc downstream regulated 1 3.34934
PTPRH protein tyrosine phosphatase, receptor type, H 3.34934
SLAMF6 SLAM family member 6 3.34934
MYOC myocilin, trabecular meshwork inducible glucocorticoid response 3.34934
FAM228A family with sequence similarity 228, member A 3.34934
GATA6 GATA binding protein 6 3.34934
SYT15 synaptotagmin XV 3.34934
HNF1B HNF1 homeobox B 3.34934
LTB lymphotoxin beta (TNF superfamily, member 3) 3.34934
FRK fyn-related Src family tyrosine kinase 3.34934
C6 complement component 6 3.34934
GSC goosecoid homeobox 3.34934
S100B S100 calcium binding protein B 3.34934
FER1L6 fer-1-like family member 6 3.34934
NTSR1 neurotensin receptor 1 (high affinity) 3.34934
LCT lactase 3.34934
C11ORF91 chromosome 11 open reading frame 91 3.34934
CLRN1 clarin 1 3.34934
WFDC8 WAP four-disulfide core domain 8 3.34934
LAIR1 leukocyte-associated immunoglobulin-like receptor 1 3.34934
TAF7L TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa 3.34934
CCDC27 coiled-coil domain containing 27 3.34934
NEDD1 neural precursor cell expressed, developmentally down-regulated 1 3.34934
DNAH12 dynein, axonemal, heavy chain 12 3.34934
SHOX2 short stature homeobox 2 3.34934
LRCOL1 leucine rich colipase-like 1 3.34934
OR13A1 olfactory receptor, family 13, subfamily A, member 1 3.34934
PRSS57 protease, serine, 57 3.34934
ZNF471 zinc finger protein 471 3.34934
SMYD1 SET and MYND domain containing 1 3.34934
GABRD gamma-aminobutyric acid (GABA) A receptor, delta 3.34934
OR9Q1 olfactory receptor, family 9, subfamily Q, member 1 3.34934
ALAS2 5'-aminolevulinate synthase 2 3.34934
APOD apolipoprotein D 3.34934
ISLR immunoglobulin superfamily containing leucine-rich repeat 3.34934
IL1A interleukin 1, alpha 3.34934
PGR progesterone receptor 3.34934
NCR3 natural cytotoxicity triggering receptor 3 3.34934
GSC2 goosecoid homeobox 2 3.34934
KLHL10 kelch-like family member 10 3.34934
MEPE matrix extracellular phosphoglycoprotein 3.34934
FKBP1C FK506 binding protein 1C 3.34934
CNGB1 cyclic nucleotide gated channel beta 1 3.34934
DRC1 dynein regulatory complex subunit 1 3.34934
GPR68 G protein-coupled receptor 68 3.34934
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 3.34934
TPPP2 tubulin polymerization-promoting protein family member 2 3.34934
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1 3.34934
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2 3.34934
KLK12 kallikrein-related peptidase 12 3.34934
ZFP92 ZFP92 zinc finger protein 3.34934
CFAP47 cilia and flagella associated protein 47 3.34934
VSTM1 V-set and transmembrane domain containing 1 3.34934
OCM oncomodulin 3.34934
BSPH1 binder of sperm protein homolog 1 3.34934
GOLGA8N golgin A8 family, member N 3.34934
CCDC166 coiled-coil domain containing 166 3.34934
LST1 leukocyte specific transcript 1 3.34934
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) 3.34934
GALNT15 polypeptide N-acetylgalactosaminyltransferase 15 3.34934
TUBAL3 tubulin, alpha-like 3 3.34934
SNTN sentan, cilia apical structure protein 3.34934
GALNTL5 polypeptide N-acetylgalactosaminyltransferase-like 5 3.34934
AOC1 amine oxidase, copper containing 1 3.34934
ASCL2 achaete-scute family bHLH transcription factor 2 3.34934
ALLC allantoicase 3.34934
TGM7 transglutaminase 7 3.34934
NLRP6 NLR family, pyrin domain containing 6 3.34934
PIK3C2G phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma 3.34934
CMPK2 cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial 3.34934
OR51I2 olfactory receptor, family 51, subfamily I, member 2 3.34934
CCDC87 coiled-coil domain containing 87 3.34934
G6PC2 glucose-6-phosphatase, catalytic, 2 3.34934
ANKRD33 ankyrin repeat domain 33 3.34934
R3HDML R3H domain containing-like 3.34934
OTX1 orthodenticle homeobox 1 3.34934
ZC3H11B zinc finger CCCH-type containing 11B pseudogene 3.34934
RBP4 retinol binding protein 4, plasma 3.34934
PLGLB2 plasminogen-like B2 3.34934
NEUROD1 neuronal differentiation 1 3.34934
TBX15 T-box 15 3.34934
NLRP3 NLR family, pyrin domain containing 3 3.34934
C9ORF72 chromosome 9 open reading frame 72 3.28206
MAP1LC3A microtubule-associated protein 1 light chain 3 alpha 3.28206
SOD2 superoxide dismutase 2, mitochondrial 3.26166
LOC124904542 uncharacterized LOC124904542 3.25363
LONRF2 LON peptidase N-terminal domain and ring finger 2 3.25363
PF4 platelet factor 4 3.25363
HJV hemojuvelin BMP co-receptor 3.25363
WDR3 WD repeat domain 3 3.24604
PIWIL4 piwi-like RNA-mediated gene silencing 4 3.0879
XK X-linked Kx blood group 3.05453
SLC47A2 solute carrier family 47 (multidrug and toxin extrusion), member 2 3.00583
SNED1 sushi, nidogen and EGF-like domains 1 2.8718
RIOK3 RIO kinase 3 2.77268
USP43 ubiquitin specific peptidase 43 2.76296
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1 2.73443
CLDND1 claudin domain containing 1 2.63747
ZBTB8A zinc finger and BTB domain containing 8A 2.45674
DPY19L1 dpy-19-like 1 (C. elegans) 2.45242
CYP4A22 cytochrome P450, family 4, subfamily A, polypeptide 22 2.40572
FOSB FBJ murine osteosarcoma viral oncogene homolog B 2.40572
CHD7 chromodomain helicase DNA binding protein 7 2.40014
MAN1A1 mannosidase, alpha, class 1A, member 1 2.39611
GHITM growth hormone inducible transmembrane protein 2.38965
PPP1R3C protein phosphatase 1, regulatory subunit 3C 2.38407
BCO2 beta-carotene oxygenase 2 2.38407
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) 2.37997
PPP1R3B protein phosphatase 1, regulatory subunit 3B 2.34875
SLC35F5 solute carrier family 35, member F5 2.34757
DCAF17 DDB1 and CUL4 associated factor 17 2.34757
DDX28 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 2.3387
TMEM39A transmembrane protein 39A 2.31487
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae) 2.30934
MME membrane metallo-endopeptidase 2.30641
AIDA axin interactor, dorsalization associated 2.29915
CDCA7L cell division cycle associated 7-like 2.25441
ITM2C integral membrane protein 2C 2.23345
CCDC71 coiled-coil domain containing 71 2.22969
ANGPTL7 angiopoietin-like 7 2.21883
CSPG4 chondroitin sulfate proteoglycan 4 2.21883
MINDY3 MINDY lysine 48 deubiquitinase 3 2.20808
TEK TEK tyrosine kinase, endothelial 2.20238
BST2 bone marrow stromal cell antigen 2 2.19184
AGO2 argonaute RISC catalytic component 2 2.17717
TTC1 tetratricopeptide repeat domain 1 2.16694
SRP72 signal recognition particle 72kDa 2.1551
CASP9 caspase 9, apoptosis-related cysteine peptidase 2.13613
STUM stum, mechanosensory transduction mediator homolog 2.11574
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 2.10502
FERMT2 fermitin family member 2 2.10502
SOWAHC sosondowah ankyrin repeat domain family member C 2.08319
ZBTB24 zinc finger and BTB domain containing 24 2.07283
ECHDC2 enoyl CoA hydratase domain containing 2 2.07267
MED28 mediator complex subunit 28 2.07153
RAD51C RAD51 paralog C 2.07153
ZNF84 zinc finger protein 84 2.07153
RTL8A retrotransposon Gag like 8A 2.07153
SNAPC3 small nuclear RNA activating complex, polypeptide 3, 50kDa 2.06598
UTP4 UTP4 small subunit processome component 2.06598
INSIG1 insulin induced gene 1 2.06598
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae) 2.06136
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 2.05457
CEP295 centrosomal protein 295kDa 2.04221
PLAAT3 phospholipase A and acyltransferase 3 2.04221
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1 2.03764
SF3B5 splicing factor 3b, subunit 5, 10kDa 2.0311
GPR63 G protein-coupled receptor 63 2.00561
PACSIN1 protein kinase C and casein kinase substrate in neurons 1 2.00147

decreased expression

Symbol Name Standardized Value
LMO1 LIM domain only 1 (rhombotin 1) -3.35844
FZD8 frizzled class receptor 8 -3.35844
C2CD4C C2 calcium-dependent domain containing 4C -3.35844
FDXACB1 ferredoxin-fold anticodon binding domain containing 1 -3.35844
DCAF4L1 DDB1 and CUL4 associated factor 4-like 1 -3.34934
ADGRE3 adhesion G protein-coupled receptor E3 -3.34934
APOB apolipoprotein B -3.34934
GPR162 G protein-coupled receptor 162 -3.34934
RASL10A RAS-like, family 10, member A -3.34934
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 -3.34934
AADACL3 arylacetamide deacetylase-like 3 -3.34934
MYOM3 myomesin 3 -3.34934
F7 coagulation factor VII (serum prothrombin conversion accelerator) -3.34934
PTPN5 protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched) -3.34934
COL15A1 collagen, type XV, alpha 1 -3.34934
CRYGN crystallin, gamma N -3.34934
CD38 CD38 molecule -3.34934
CNDP1 carnosine dipeptidase 1 (metallopeptidase M20 family) -3.34934
MYT1L myelin transcription factor 1-like -3.34934
ANKRD65 ankyrin repeat domain 65 -3.34934
PCDHA3 protocadherin alpha 3 -3.34934
MUCL3 mucin like 3 -3.34934
YIPF7 Yip1 domain family, member 7 -3.34934
ZGLP1 zinc finger, GATA-like protein 1 -3.34934
CD200R1 CD200 receptor 1 -3.34934
SPRR2F small proline-rich protein 2F -3.34934
MYOT myotilin -3.34934
RUMY3 RUMY family member 3 -3.34934
ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 -3.34934
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 -3.34934
IRF5 interferon regulatory factor 5 -3.34934
SNRK SNF related kinase -3.34934
SCUBE2 signal peptide, CUB domain, EGF-like 2 -3.34232
XKR9 XK, Kell blood group complex subunit-related family, member 9 -3.34232
DGKA diacylglycerol kinase, alpha 80kDa -3.30454
SLC52A3 solute carrier family 52 (riboflavin transporter), member 3 -3.30454
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit -3.24607
TANGO6 transport and golgi organization 6 homolog (Drosophila) -3.21494
INCENP inner centromere protein antigens 135/155kDa -3.10272
ABHD11 abhydrolase domain containing 11 -2.91722
KRR1 KRR1, small subunit (SSU) processome component, homolog (yeast) -2.85446
CFAP70 cilia and flagella associated protein 70 -2.80745
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 -2.80745
ARHGAP17 Rho GTPase activating protein 17 -2.73839
MID2 midline 2 -2.73839
TMEM123 transmembrane protein 123 -2.65095
FADS1 fatty acid desaturase 1 -2.64416
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 -2.58266
GFRA3 GDNF family receptor alpha 3 -2.57489
CDKL3 cyclin-dependent kinase-like 3 -2.50967
TEX14 testis expressed 14 -2.48858
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha -2.48379
RNF44 ring finger protein 44 -2.47649
VPS35L VPS35 endosomal protein sorting factor like -2.39741
ZSCAN25 zinc finger and SCAN domain containing 25 -2.39097
CRLS1 cardiolipin synthase 1 -2.34943
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -2.34757
CCNK cyclin K -2.33887
SFT2D3 SFT2 domain containing 3 -2.33224
CDH1 cadherin 1, type 1, E-cadherin (epithelial) -2.32669
CSKMT citrate synthase lysine methyltransferase -2.30641
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit -2.30311
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 -2.3019
PTPDC1 protein tyrosine phosphatase domain containing 1 -2.28608
ERC2 ELKS/RAB6-interacting/CAST family member 2 -2.27186
HES1 hes family bHLH transcription factor 1 -2.27129
FH fumarate hydratase -2.2655
ARHGAP30 Rho GTPase activating protein 30 -2.26455
ASB2 ankyrin repeat and SOCS box containing 2 -2.26337
ZNF774 zinc finger protein 774 -2.26337
TNPO2 transportin 2 -2.2627
PTPRR protein tyrosine phosphatase, receptor type, R -2.25441
ZBED3 zinc finger, BED-type containing 3 -2.22969
WBP2NL WBP2 N-terminal like -2.21883
TINCR tissue differentiation-inducing non-protein coding RNA -2.21883
SUGP2 SURP and G patch domain containing 2 -2.21737
SETD7 SET domain containing (lysine methyltransferase) 7 -2.20716
LRRC19 leucine rich repeat containing 19 -2.20238
ECSCR endothelial cell surface expressed chemotaxis and apoptosis regulator -2.19184
ZKSCAN1 zinc finger with KRAB and SCAN domains 1 -2.18809
PKD1L2 polycystic kidney disease 1-like 2 (gene/pseudogene) -2.17717
FBLIM1 filamin binding LIM protein 1 -2.1517
ESRRG estrogen-related receptor gamma -2.14494
ZNF677 zinc finger protein 677 -2.1391
RFX2 regulatory factor X, 2 (influences HLA class II expression) -2.13897
GRTP1 growth hormone regulated TBC protein 1 -2.13897
BOC BOC cell adhesion associated, oncogene regulated -2.13613
APAF1 apoptotic peptidase activating factor 1 -2.12477
EHD4 EH-domain containing 4 -2.11082
POLR2G polymerase (RNA) II (DNA directed) polypeptide G -2.09621
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B -2.08319
MTFMT mitochondrial methionyl-tRNA formyltransferase -2.07153
KAZN kazrin, periplakin interacting protein -2.07055
PEDS1 plasmanylethanolamine desaturase 1 -2.0698
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2 -2.06598
HSCB HscB mitochondrial iron-sulfur cluster co-chaperone -2.06598
OSMR oncostatin M receptor -2.06598
CSMD1 CUB and Sushi multiple domains 1 -2.06318
DAP3 death associated protein 3 -2.0597
AIG1 androgen-induced 1 -2.04199
APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 -2.03533
ARF4 ADP-ribosylation factor 4 -2.03244
MLEC malectin -2.01895
OXNAD1 oxidoreductase NAD-binding domain containing 1 -2.01824
BLOC1S4 biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino -2.00777
LCMT1 leucine carboxyl methyltransferase 1 -2.00438
CDH3 cadherin 3, type 1, P-cadherin (placental) -2.00147
DVL2 dishevelled segment polarity protein 2 -2.00147
RNF24 ring finger protein 24 -2.00147
CEP192 centrosomal protein 192kDa -2.00147