PON1 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description paraoxonase 1|The enzyme encoded by this gene is an arylesterase that mainly hydrolyzes paroxon to produce p-nitrophenol. Paroxon is an organophosphorus anticholinesterase compound that is produced in vivo by oxidation of the insecticide parathion. Polymorphisms in this gene are a risk factor in coronary artery disease. The gene is found in a cluster of three related paraoxonase genes at 7q21.3. [provided by RefSeq, Oct 2008] (NCBI Entrez Gene Database, 5444)
External Link https://ncbi.nlm.nih.gov/gene/5444
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Genes

499 genes differentially expressed following the PON1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
CSTA cystatin A (stefin A) 0.0242878
S100A8 S100 calcium binding protein A8 0.0239048
KRT6A keratin 6A, type II 0.0165322
S100A2 S100 calcium binding protein A2 0.0164385
CXCL8 chemokine (C-X-C motif) ligand 8 0.0164133
KRT5 keratin 5, type II 0.0161193
AQP3 aquaporin 3 (Gill blood group) 0.0157715
S100A9 S100 calcium binding protein A9 0.0155215
KRT13 keratin 13, type I 0.0143385
SPRR3 small proline-rich protein 3 0.0140695
KRT15 keratin 15, type I 0.013348
SPRR1B small proline-rich protein 1B 0.0131992
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.0130205
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.0129235
GNAS GNAS complex locus 0.0124392
CXCL2 chemokine (C-X-C motif) ligand 2 0.012247
KRT14 keratin 14, type I 0.0121875
ADM adrenomedullin 0.0119647
MNAT1 MNAT CDK-activating kinase assembly factor 1 0.0119637
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14 0.0118096
IL1RN interleukin 1 receptor antagonist 0.0115465
CAST calpastatin 0.0113881
MYO1B myosin IB 0.011368
DEFB1 defensin, beta 1 0.0110377
TACSTD2 tumor-associated calcium signal transducer 2 0.0107354
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.0106709
SPRR2B small proline-rich protein 2B 0.0106208
RGCC regulator of cell cycle 0.0105339
DSG3 desmoglein 3 0.0103168
MPO myeloperoxidase 0.0102737
CAV2 caveolin 2 0.0102361
BTG3 BTG family, member 3 0.0102316
EIF5 eukaryotic translation initiation factor 5 0.0102156
IRS2 insulin receptor substrate 2 0.010148
CRK v-crk avian sarcoma virus CT10 oncogene homolog 0.0100498
KRT6B keratin 6B, type II 0.0100108
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 0.0100079
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 0.00995134
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.00989027
CFD complement factor D (adipsin) 0.00978714
MXI1 MAX interactor 1, dimerization protein 0.00977994
IFI27 interferon, alpha-inducible protein 27 0.00961006
DDIT3 DNA-damage-inducible transcript 3 0.00942951
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) 0.00931907
RHCG Rh family, C glycoprotein 0.00922873
ANXA1 annexin A1 0.0091719
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 0.00916891
GRB7 growth factor receptor-bound protein 7 0.00911456
CLCA2 chloride channel accessory 2 0.00894774
CSRP2 cysteine and glycine-rich protein 2 0.00891234
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 0.00885676
SLC31A2 solute carrier family 31 (copper transporter), member 2 0.00866408
HACD3 3-hydroxyacyl-CoA dehydratase 3 0.00856564
KRT17 keratin 17, type I 0.00853293
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 0.00850376
ECM1 extracellular matrix protein 1 0.00846183
AKAP12 A kinase (PRKA) anchor protein 12 0.00845104
RRAGD Ras-related GTP binding D 0.0084338
ATF3 activating transcription factor 3 0.00839552
POPDC3 popeye domain containing 3 0.00835806
CDK14 cyclin-dependent kinase 14 0.00835128
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial 0.00834135
THBS2 thrombospondin 2 0.00832124
TP63 tumor protein p63 0.00832039
LINC00623 long intergenic non-protein coding RNA 623 0.00831602
ZNF395 zinc finger protein 395 0.00828745
HIST1H2BD histone cluster 1, H2bd 0.00828727
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 0.00828559
TRAM1 translocation associated membrane protein 1 0.00823
STOM stomatin 0.00821578
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 0.00818443
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 0.00817387
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 0.0081694
RAB32 RAB32, member RAS oncogene family 0.00815476
KLHL24 kelch-like family member 24 0.00811181
S100A14 S100 calcium binding protein A14 0.00810083
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) 0.0080802
COL11A1 collagen, type XI, alpha 1 0.00807279
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15 0.00806526
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.00804573
SPRR1A small proline-rich protein 1A 0.00804459
PRPF4 pre-mRNA processing factor 4 0.00799835
PKP1 plakophilin 1 0.00795298
ABHD4 abhydrolase domain containing 4 0.00795127
EGR1 early growth response 1 0.00794167
CEMIP cell migration inducing protein, hyaluronan binding 0.00793968
JAG1 jagged 1 0.00793767
CYP4F3 cytochrome P450, family 4, subfamily F, polypeptide 3 0.00790931
EGLN1 egl-9 family hypoxia-inducible factor 1 0.00790854
ZNF185 zinc finger protein 185 (LIM domain) 0.00790155
PLAU plasminogen activator, urokinase 0.00789901
SLC25A46 solute carrier family 25, member 46 0.00788803
PTHLH parathyroid hormone-like hormone 0.00787877
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 0.00786622
ISG20 interferon stimulated exonuclease gene 20kDa 0.00786011
DAXX death-domain associated protein 0.00785842
CALML3 calmodulin-like 3 0.00785471
KRT81 keratin 81, type II 0.00785109
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.00783517
TPM4 tropomyosin 4 0.00782555
IFI16 interferon, gamma-inducible protein 16 0.00780672
LMCD1 LIM and cysteine-rich domains 1 0.00780341
STC2 stanniocalcin 2 0.00779904
LPAR6 lysophosphatidic acid receptor 6 0.00777689
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa 0.00776254
KLF9 Kruppel-like factor 9 0.00775063
C21ORF91 chromosome 21 open reading frame 91 0.0076401
GLUL glutamate-ammonia ligase 0.00759618
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 0.00759572
LYST lysosomal trafficking regulator 0.00757349
WDR26 WD repeat domain 26 0.0075697
LAMP3 lysosomal-associated membrane protein 3 0.00755996
ELANE elastase, neutrophil expressed 0.00752435
KDM5B lysine (K)-specific demethylase 5B 0.00752109
TIMP3 TIMP metallopeptidase inhibitor 3 0.00745776
S100A10 S100 calcium binding protein A10 0.00745025
MID1 midline 1 0.00734628
THBD thrombomodulin 0.00734241
DUSP10 dual specificity phosphatase 10 0.00734137
MMP10 matrix metallopeptidase 10 0.00732304
PPL periplakin 0.00730909
COL5A2 collagen, type V, alpha 2 0.0073052
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.0073016
AQP9 aquaporin 9 0.00730143
ERO1A endoplasmic reticulum oxidoreductase 1 alpha 0.00728845
MIR22HG MIR22 host gene 0.00726086
HECA headcase homolog (Drosophila) 0.00723096
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 0.00722012
PHLDA1 pleckstrin homology-like domain, family A, member 1 0.00718309
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B 0.00717562
DMAC2L distal membrane arm assembly component 2 like 0.00717283
USP15 ubiquitin specific peptidase 15 0.0071193
CXADR coxsackie virus and adenovirus receptor 0.00710896
TRIM16 tripartite motif containing 16 0.00707057
CES1 carboxylesterase 1 0.00705878
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.00703782
NOX4 NADPH oxidase 4 0.00701223
PGAP3 post-GPI attachment to proteins 3 0.00699687
CANX calnexin 0.0069861
PDGFC platelet derived growth factor C 0.00698275
TRIM29 tripartite motif containing 29 0.00697487
ITGA6 integrin, alpha 6 0.00696771
STC1 stanniocalcin 1 0.00694851
PTBP3 polypyrimidine tract binding protein 3 0.0069471
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 0.00693019
IRF6 interferon regulatory factor 6 0.00690701
DAZAP2 DAZ associated protein 2 0.00689587
SCEL sciellin 0.00688902
PITX1 paired-like homeodomain 1 0.00686977
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 0.00686391
TGFA transforming growth factor, alpha 0.00686178
TBXA2R thromboxane A2 receptor 0.0068201
CASP2 caspase 2, apoptosis-related cysteine peptidase 0.00681026
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 0.00678022
LYRM1 LYR motif containing 1 0.00676497
SET SET nuclear proto-oncogene 0.00673537
FGF13 fibroblast growth factor 13 0.00673347
NMD3 NMD3 ribosome export adaptor 0.00672837
SUSD4 sushi domain containing 4 0.00670519
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 0.00669266
TSPAN31 tetraspanin 31 0.0066694
MCAM melanoma cell adhesion molecule 0.00666556
BAZ1A bromodomain adjacent to zinc finger domain, 1A 0.00665934
ELL2 elongation factor, RNA polymerase II, 2 0.00665845
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial) 0.00664298
RHOB ras homolog family member B 0.00663753
CYB5R4 cytochrome b5 reductase 4 0.00663179
PTGES prostaglandin E synthase 0.00662474
S100A7 S100 calcium binding protein A7 0.00661709
UBE2L6 ubiquitin-conjugating enzyme E2L 6 0.00661316
INHBA inhibin, beta A 0.00657899
CD44 CD44 molecule (Indian blood group) 0.00655165
HSPA4 heat shock 70kDa protein 4 0.00654033
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 0.00652016
ACOT9 acyl-CoA thioesterase 9 0.00651396
IL1A interleukin 1, alpha 0.00650534
ECHDC3 enoyl CoA hydratase domain containing 3 0.00648332
CYB5A cytochrome b5 type A (microsomal) 0.00648188
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 0.00647617
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 0.00647464
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 0.00646538
FRS2 fibroblast growth factor receptor substrate 2 0.00644859
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F 0.00643972
PTP4A1 protein tyrosine phosphatase type IVA, member 1 0.00640118
FXYD3 FXYD domain containing ion transport regulator 3 0.00638617
DBT dihydrolipoamide branched chain transacylase E2 0.00638495
DIPK1A divergent protein kinase domain 1A 0.00638326
NIBAN1 niban apoptosis regulator 1 0.00638318
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1 0.0063727
HIST1H2AC histone cluster 1, H2ac 0.00637236
POU4F1 POU class 4 homeobox 1 0.00636466
DIO1 deiodinase, iodothyronine, type I 0.00634655
HMOX1 heme oxygenase 1 0.00634128
TUFT1 tuftelin 1 0.00633328
ERP44 endoplasmic reticulum protein 44 0.00631299
BHMT betaine--homocysteine S-methyltransferase 0.00631029
IDI1 isopentenyl-diphosphate delta isomerase 1 0.00629461
GPNMB glycoprotein (transmembrane) nmb 0.00628151
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa 0.00626037
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 0.00625858
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 0.00625641
CD36 CD36 molecule (thrombospondin receptor) 0.00624247
UBFD1 ubiquitin family domain containing 1 0.00624128
SGK1 serum/glucocorticoid regulated kinase 1 0.00622981
SLC38A2 solute carrier family 38, member 2 0.0062291
UBASH3A ubiquitin associated and SH3 domain containing A 0.00620572
SLC6A15 solute carrier family 6 (neutral amino acid transporter), member 15 0.00620265
EHD3 EH-domain containing 3 0.0061894
MCL1 myeloid cell leukemia 1 0.00618627
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 0.00617538
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) 0.00617083
SVIL supervillin 0.00616241
DCBLD2 discoidin, CUB and LCCL domain containing 2 0.00615631
BID BH3 interacting domain death agonist 0.00612179
GBP2 guanylate binding protein 2, interferon-inducible 0.0061142
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 0.00611315
CCL14 chemokine (C-C motif) ligand 14 0.00611082
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8 0.0061074
MOCOS molybdenum cofactor sulfurase 0.00610287
MEF2A myocyte enhancer factor 2A 0.0060987
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 0.00609568
FOXC1 forkhead box C1 0.0060864
DSC2 desmocollin 2 0.00608313
PPP1R3C protein phosphatase 1, regulatory subunit 3C 0.00608281
KLHL21 kelch-like family member 21 0.00608063
ARL2BP ADP-ribosylation factor-like 2 binding protein 0.00607432
RSL1D1 ribosomal L1 domain containing 1 0.00606511
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 0.00604559
PALLD palladin, cytoskeletal associated protein 0.00603947
HSPA6 heat shock 70kDa protein 6 (HSP70B') 0.00601223
WDR41 WD repeat domain 41 0.00600892
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 0.005992
MAST4 microtubule associated serine/threonine kinase family member 4 0.00598224
TRIM22 tripartite motif containing 22 0.00595776
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) 0.00594309
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3 0.00593781
POSTN periostin, osteoblast specific factor 0.0059363
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 0.00593588
TNC tenascin C 0.00593097
CIAO3 cytosolic iron-sulfur assembly component 3 0.00592954
RIN2 Ras and Rab interactor 2 0.00592949
PRSS21 protease, serine, 21 (testisin) 0.00592252
RNFT1 ring finger protein, transmembrane 1 0.00591954
ABHD17B abhydrolase domain containing 17B 0.00590735
C18ORF25 chromosome 18 open reading frame 25 0.005892
CALD1 caldesmon 1 0.00588798
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 0.00587973
UBE2B ubiquitin-conjugating enzyme E2B 0.00586809
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.00585798

decreased expression

Symbol Name Standardized Value
DLK1 delta-like 1 homolog (Drosophila) -0.0181399
PEG3 paternally expressed 3 -0.015686
SCG5 secretogranin V -0.0155056
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) -0.0138036
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 -0.0134963
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 -0.0129354
RUFY3 RUN and FYVE domain containing 3 -0.0124076
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 -0.0121908
SPINK1 serine peptidase inhibitor, Kazal type 1 -0.0117474
TSPAN8 tetraspanin 8 -0.0116215
ACSL5 acyl-CoA synthetase long-chain family member 5 -0.010801
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) -0.0106817
ICMT isoprenylcysteine carboxyl methyltransferase -0.0104904
SLC26A3 solute carrier family 26 (anion exchanger), member 3 -0.010449
MFAP2 microfibrillar-associated protein 2 -0.0102081
PROM1 prominin 1 -0.0101674
CASP10 caspase 10, apoptosis-related cysteine peptidase -0.0101581
HEPH hephaestin -0.0100988
CLDN3 claudin 3 -0.0100374
PLBD1 phospholipase B domain containing 1 -0.0100358
SLC26A2 solute carrier family 26 (anion exchanger), member 2 -0.0100059
CD320 CD320 molecule -0.00999203
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 -0.00998453
ASRGL1 asparaginase like 1 -0.0099748
PDGFRA platelet-derived growth factor receptor, alpha polypeptide -0.00991357
OGN osteoglycin -0.00984655
BIN1 bridging integrator 1 -0.00980277
APOD apolipoprotein D -0.00978645
HMG20B high mobility group 20B -0.00961141
MYBPC1 myosin binding protein C, slow type -0.00960672
AOC1 amine oxidase, copper containing 1 -0.00945134
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 -0.0093654
SIRT3 sirtuin 3 -0.00931602
GLS glutaminase -0.00930183
GLB1L2 galactosidase, beta 1-like 2 -0.00919121
FCGBP Fc fragment of IgG binding protein -0.00905372
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 -0.0090268
PTCH1 patched 1 -0.00896087
COLEC12 collectin sub-family member 12 -0.0089499
PRR7 proline rich 7 (synaptic) -0.00872853
GRIA2 glutamate receptor, ionotropic, AMPA 2 -0.00872425
COL6A2 collagen, type VI, alpha 2 -0.00870966
NDP Norrie disease (pseudoglioma) -0.00867028
EML3 echinoderm microtubule associated protein like 3 -0.00852081
NPY neuropeptide Y -0.00847724
NFASC neurofascin -0.00841479
MMP7 matrix metallopeptidase 7 -0.0084064
ARPP19 cAMP-regulated phosphoprotein, 19kDa -0.00834333
KAZN kazrin, periplakin interacting protein -0.00833169
TLCD3A TLC domain containing 3A -0.00831998
GREB1 growth regulation by estrogen in breast cancer 1 -0.00826065
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) -0.00821986
TUBB4B tubulin, beta 4B class IVb -0.00797293
MBL2 mannose-binding lectin (protein C) 2, soluble -0.00787732
CDKN2A cyclin-dependent kinase inhibitor 2A -0.00782516
PRUNE2 prune homolog 2 (Drosophila) -0.00781121
AGR2 anterior gradient 2 -0.00780635
LPCAT1 lysophosphatidylcholine acyltransferase 1 -0.00779426
LDOC1 leucine zipper, down-regulated in cancer 1 -0.00778206
IGFBP1 insulin-like growth factor binding protein 1 -0.00778088
OLFM4 olfactomedin 4 -0.00774909
INSM1 insulinoma-associated 1 -0.00774551
SLIT2 slit homolog 2 (Drosophila) -0.00773279
KRT20 keratin 20, type I -0.0076978
RTN1 reticulon 1 -0.00769236
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 -0.00768287
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta -0.00767538
ATP5F1D ATP synthase F1 subunit delta -0.00766501
SOX17 SRY (sex determining region Y)-box 17 -0.00764966
IQGAP2 IQ motif containing GTPase activating protein 2 -0.00763988
MGLL monoglyceride lipase -0.00763615
FBLN5 fibulin 5 -0.00759604
AFP alpha-fetoprotein -0.00759332
MDK midkine (neurite growth-promoting factor 2) -0.00757752
PPP1R13B protein phosphatase 1, regulatory subunit 13B -0.00754423
KIF2C kinesin family member 2C -0.00752504
ZBTB20 zinc finger and BTB domain containing 20 -0.00747469
RAB40B RAB40B, member RAS oncogene family -0.00744224
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) -0.00743084
SMTN smoothelin -0.0074146
MAP2K2 mitogen-activated protein kinase kinase 2 -0.00739097
LEFTY1 left-right determination factor 1 -0.0073857
FABP1 fatty acid binding protein 1, liver -0.00737917
LMNB2 lamin B2 -0.00737561
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide -0.00732591
PLP1 proteolipid protein 1 -0.00732552
PGLS 6-phosphogluconolactonase -0.00732219
DAPK1 death-associated protein kinase 1 -0.00732215
TNNI2 troponin I type 2 (skeletal, fast) -0.00730169
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 -0.00727408
PDZRN3 PDZ domain containing ring finger 3 -0.00722638
ICAM2 intercellular adhesion molecule 2 -0.00722217
MANSC1 MANSC domain containing 1 -0.00719508
CIT citron rho-interacting serine/threonine kinase -0.00719151
DPYSL2 dihydropyrimidinase-like 2 -0.00718755
TOMM34 translocase of outer mitochondrial membrane 34 -0.00718498
SFRP4 secreted frizzled-related protein 4 -0.00718069
TFF3 trefoil factor 3 (intestinal) -0.00714238
FLNC filamin C, gamma -0.00712597
TUBB3 tubulin, beta 3 class III -0.00712123
MEG3 maternally expressed 3 (non-protein coding) -0.0071128
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor -0.00710413
TMEM109 transmembrane protein 109 -0.00705242
SFRP1 secreted frizzled-related protein 1 -0.00703135
NEFH neurofilament, heavy polypeptide -0.0069906
ELN elastin -0.00696094
LOC283683 uncharacterized LOC283683 -0.00695525
SI sucrase-isomaltase (alpha-glucosidase) -0.00694556
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2 -0.00693777
NAP1L3 nucleosome assembly protein 1-like 3 -0.0068925
CDCA4 cell division cycle associated 4 -0.00689132
CXCL14 chemokine (C-X-C motif) ligand 14 -0.00688531
OAZ1 ornithine decarboxylase antizyme 1 -0.00686595
MMP3 matrix metallopeptidase 3 -0.00685894
AMD1 adenosylmethionine decarboxylase 1 -0.0068586
MYO6 myosin VI -0.00685214
SELENOW selenoprotein W -0.00684745
TGFBR3 transforming growth factor, beta receptor III -0.00684075
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 -0.00683205
PTP4A2 protein tyrosine phosphatase type IVA, member 2 -0.00682432
LGALS13 lectin, galactoside-binding, soluble, 13 -0.0068223
EGR3 early growth response 3 -0.0068212
PRKCZ protein kinase C, zeta -0.00680604
ANXA5 annexin A5 -0.00676026
QPRT quinolinate phosphoribosyltransferase -0.00671297
GOLGA8H golgin A8 family, member H -0.00671054
THYN1 thymocyte nuclear protein 1 -0.00670089
F3 coagulation factor III (thromboplastin, tissue factor) -0.00668296
PCP4 Purkinje cell protein 4 -0.00665925
ENO1 enolase 1, (alpha) -0.00665859
EPHB2 EPH receptor B2 -0.0066498
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein -0.00663468
DPP4 dipeptidyl-peptidase 4 -0.00663022
ELOVL1 ELOVL fatty acid elongase 1 -0.00662956
LSP1 lymphocyte-specific protein 1 -0.00662604
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 -0.0066071
ACSM3 acyl-CoA synthetase medium-chain family member 3 -0.00656785
RPIA ribose 5-phosphate isomerase A -0.00656705
NECTIN3 nectin cell adhesion molecule 3 -0.00655756
EMILIN1 elastin microfibril interfacer 1 -0.00654509
TARP TCR gamma alternate reading frame protein -0.00650758
RCAN2 regulator of calcineurin 2 -0.00649567
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 -0.00647927
TSEN2 TSEN2 tRNA splicing endonuclease subunit -0.00641816
KIF1A kinesin family member 1A -0.00641645
PRKCA protein kinase C, alpha -0.00640594
SNAP25 synaptosomal-associated protein, 25kDa -0.00639105
KIAA0125 KIAA0125 -0.00638403
ENC1 ectodermal-neural cortex 1 (with BTB domain) -0.00637692
TPI1 triosephosphate isomerase 1 -0.00635874
TUBG1 tubulin, gamma 1 -0.00635022
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 -0.00632947
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein -0.00632828
HELLS helicase, lymphoid-specific -0.00632487
NINJ2 ninjurin 2 -0.00630834
CAND2 cullin-associated and neddylation-dissociated 2 (putative) -0.00628975
COL1A2 collagen, type I, alpha 2 -0.00627237
DHRS2 dehydrogenase/reductase (SDR family) member 2 -0.00626387
MATN2 matrilin 2 -0.00626381
PTGIS prostaglandin I2 (prostacyclin) synthase -0.00624867
PLPP2 phospholipid phosphatase 2 -0.0062441
NANOG Nanog homeobox -0.00622706
PNPLA6 patatin-like phospholipase domain containing 6 -0.00621887
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) -0.00619794
AMH anti-Mullerian hormone -0.00619626
PLAGL1 pleiomorphic adenoma gene-like 1 -0.00619097
APLP1 amyloid beta (A4) precursor-like protein 1 -0.0061822
MXRA8 matrix-remodelling associated 8 -0.00617638
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 -0.00617176
STK25 serine/threonine kinase 25 -0.00613629
MECOM MDS1 and EVI1 complex locus -0.00611829
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) -0.00610569
TPBG trophoblast glycoprotein -0.00609194
TMC5 transmembrane channel-like 5 -0.00608428
MPRIP myosin phosphatase Rho interacting protein -0.00608322
SDF4 stromal cell derived factor 4 -0.00608231
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta -0.00606703
FANCL Fanconi anemia, complementation group L -0.00606636
ZNF518A zinc finger protein 518A -0.00606026
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 -0.00605638
NAP1L4 nucleosome assembly protein 1-like 4 -0.00605108
CTSZ cathepsin Z -0.00604703
LAMP5 lysosomal-associated membrane protein family, member 5 -0.00604587
PRKDC protein kinase, DNA-activated, catalytic polypeptide -0.00603529
PTP4A3 protein tyrosine phosphatase type IVA, member 3 -0.00603155
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 -0.00602746
OGFOD3 2-oxoglutarate and iron-dependent oxygenase domain containing 3 -0.00600629
CLCA1 chloride channel accessory 1 -0.00599109
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1 -0.0059799
NARF nuclear prelamin A recognition factor -0.00597701
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -0.00596989
GOLGA8A golgin A8 family, member A -0.00596673
COL9A2 collagen, type IX, alpha 2 -0.00596332
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.00595218
USP32P2 ubiquitin specific peptidase 32 pseudogene 2 -0.00594729
LGALS1 lectin, galactoside-binding, soluble, 1 -0.00592987
MYOT myotilin -0.00591809
ARID4A AT rich interactive domain 4A (RBP1-like) -0.00591605
ISOC1 isochorismatase domain containing 1 -0.00590629
SGMS1 sphingomyelin synthase 1 -0.00588995
SPON1 spondin 1, extracellular matrix protein -0.00587201
VNN1 vanin 1 -0.00584825
RAD21 RAD21 homolog (S. pombe) -0.00584544
ARHGAP22 Rho GTPase activating protein 22 -0.0058451
UBE2S ubiquitin-conjugating enzyme E2S -0.00583719
NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) -0.00583248
TECR trans-2,3-enoyl-CoA reductase -0.00580869
FGL2 fibrinogen-like 2 -0.0057904
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -0.00577431
PDPK1 3-phosphoinositide dependent protein kinase 1 -0.00577014
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B -0.00576984
SRPX2 sushi-repeat containing protein, X-linked 2 -0.00575339
ENG endoglin -0.00575334
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa -0.00574268
MEF2C myocyte enhancer factor 2C -0.00573638
CAMK1 calcium/calmodulin-dependent protein kinase I -0.00573084
TACC1 transforming, acidic coiled-coil containing protein 1 -0.00573022
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 -0.00572995
THBS4 thrombospondin 4 -0.00570803
PYCR1 pyrroline-5-carboxylate reductase 1 -0.00570178
CRLF1 cytokine receptor-like factor 1 -0.00570083
TMPRSS2 transmembrane protease, serine 2 -0.00569526
SPAG16 sperm associated antigen 16 -0.0056782
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) -0.0056719
PHLDA2 pleckstrin homology-like domain, family A, member 2 -0.005668
FBLN1 fibulin 1 -0.00566264
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 -0.00565734
SPRY2 sprouty homolog 2 (Drosophila) -0.00565717
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 -0.00565634
PWP1 PWP1 homolog (S. cerevisiae) -0.00564768
DEGS1 delta(4)-desaturase, sphingolipid 1 -0.00564309
STMN2 stathmin 2 -0.00562827
MCUB mitochondrial calcium uniporter dominant negative subunit beta -0.00561526
NCAPD3 non-SMC condensin II complex, subunit D3 -0.00560698
APOA1 apolipoprotein A-I -0.00560178
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 -0.00558974
P4HB prolyl 4-hydroxylase, beta polypeptide -0.00557874
EFNB2 ephrin-B2 -0.00557537
TRIM37 tripartite motif containing 37 -0.0055562
ACADVL acyl-CoA dehydrogenase, very long chain -0.00554528
MRPL12 mitochondrial ribosomal protein L12 -0.00554498
GAS7 growth arrest-specific 7 -0.00554166
CDC20 cell division cycle 20 -0.00554017
DHRS11 dehydrogenase/reductase (SDR family) member 11 -0.00553876
TRPM4 transient receptor potential cation channel, subfamily M, member 4 -0.00553809
SIDT2 SID1 transmembrane family, member 2 -0.00553432
PPARG peroxisome proliferator-activated receptor gamma -0.00553139
HAS2 hyaluronan synthase 2 -0.00552667
C9ORF16 chromosome 9 open reading frame 16 -0.00552019
BST2 bone marrow stromal cell antigen 2 -0.00551583