POP1 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)|This gene encodes the protein subunit of two different small nucleolar ribonucleoprotein complexes: the endoribonuclease for mitochondrial RNA processing complex and the ribonuclease P complex. The encoded protein is a ribonuclease that localizes to the nucleus and functions in pre-RNA processing. This protein is also an autoantigen in patients suffering from connective tissue diseases. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009] (NCBI Entrez Gene Database, 10940)
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Genes

110 genes differentially expressed following the POP1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
COLEC12 collectin sub-family member 12 2.24459
RHOJ ras homolog family member J 2.24459
DCC DCC netrin 1 receptor 2.24459
RCAN1 regulator of calcineurin 1 2.24459
KATNB1 katanin p80 (WD repeat containing) subunit B 1 2.24459
MATR3 matrin 3 2.20948
ZBTB41 zinc finger and BTB domain containing 41 2.18279
EBF1 early B-cell factor 1 2.18279
ZDHHC1 zinc finger, DHHC-type containing 1 2.18279
OSGIN2 oxidative stress induced growth inhibitor family member 2 2.18279
PGBD1 piggyBac transposable element derived 1 2.18279
PTP4A3 protein tyrosine phosphatase type IVA, member 3 2.12303
MIER3 mesoderm induction early response 1, family member 3 2.12303
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila) 2.12303
PYROXD1 pyridine nucleotide-disulphide oxidoreductase domain 1 2.12303
ZCCHC10 zinc finger, CCHC domain containing 10 2.12303
GLRA2 glycine receptor, alpha 2 2.12303
HEATR4 HEAT repeat containing 4 2.11526
RSPO4 R-spondin 4 2.11526
RPS21-DT RPS21 divergent transcript 2.11526
STK40 serine/threonine kinase 40 2.11526
LTBP3 latent transforming growth factor beta binding protein 3 2.11526
ETFRF1 electron transfer flavoprotein regulatory factor 1 2.11526
PDE4B phosphodiesterase 4B, cAMP-specific 2.11526
CLDN12 claudin 12 2.11526
EMILIN2 elastin microfibril interfacer 2 2.11526
BAALC brain and acute leukemia, cytoplasmic 2.11526
STPG1 sperm-tail PG-rich repeat containing 1 2.11526
ZNF862 zinc finger protein 862 2.11526
EARS2 glutamyl-tRNA synthetase 2, mitochondrial 2.11526
DEPDC1 DEP domain containing 1 2.11526
FNTB farnesyltransferase, CAAX box, beta 2.11526
SNX25 sorting nexin 25 2.11526
LRWD1 leucine-rich repeats and WD repeat domain containing 1 2.11526
MTARC2 mitochondrial amidoxime reducing component 2 2.11526
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 2.11526
PCDH15 protocadherin-related 15 2.11526
ZNF292 zinc finger protein 292 2.11526
TIMP4 TIMP metallopeptidase inhibitor 4 2.11526
BABAM1 BRISC and BRCA1 A complex member 1 2.11526
TAC4 tachykinin 4 (hemokinin) 2.11526
JAK2 Janus kinase 2 2.11526
KLHDC9 kelch domain containing 9 2.11526
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase 2.11526
ERAP1 endoplasmic reticulum aminopeptidase 1 2.11526
LRRK1 leucine-rich repeat kinase 1 2.11526
SLC35E4 solute carrier family 35, member E4 2.11526
SFXN4 sideroflexin 4 2.11526
CDKN2AIP CDKN2A interacting protein 2.11526
MFAP3L microfibrillar-associated protein 3-like 2.11526
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 2.11526
ZNF415 zinc finger protein 415 2.11526
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 2.11526
SAXO2 stabilizer of axonemal microtubules 2 2.11526
DOCK8 dedicator of cytokinesis 8 2.11526
FOXP2 forkhead box P2 2.11526
BCL10 B-cell CLL/lymphoma 10 2.10454
DPYSL5 dihydropyrimidinase-like 5 2.09193
MPP7 membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7) 2.09193
DMWD dystrophia myotonica, WD repeat containing 2.09193
OGFOD1 2-oxoglutarate and iron-dependent oxygenase domain containing 1 2.09193
RNF166 ring finger protein 166 2.09193
TMEM163 transmembrane protein 163 2.07774
ADAM28 ADAM metallopeptidase domain 28 2.04727
C10ORF143 chromosome 10 open reading frame 143 2.04727
CLK4 CDC-like kinase 4 2.04727
C1ORF115 chromosome 1 open reading frame 115 2.04727
CAPN2 calpain 2, (m/II) large subunit 2.04727
IQCK IQ motif containing K 2.00035
EGF epidermal growth factor 2.00035
SETMAR SET domain and mariner transposase fusion gene 2.00035
BCO2 beta-carotene oxygenase 2 2.00035

decreased expression

Symbol Name Standardized Value
ENTREP1 endosomal transmembrane epsin interactor 1 -2.24459
KIF20A kinesin family member 20A -2.24459
PRKD2 protein kinase D2 -2.24459
XTBD1 XRN2 binding domain containing 1 -2.24459
GIPC1 GIPC PDZ domain containing family, member 1 -2.20948
TTLL4 tubulin tyrosine ligase-like family member 4 -2.20948
MARVELD1 MARVEL domain containing 1 -2.20948
ARL14EP ADP-ribosylation factor-like 14 effector protein -2.20948
OBSL1 obscurin-like 1 -2.20948
SLC12A9 solute carrier family 12, member 9 -2.18279
DMGDH dimethylglycine dehydrogenase -2.12303
VIPAS39 VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog -2.12303
TANC1 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 -2.12303
SETDB2 SET domain, bifurcated 2 -2.12303
GLB1 galactosidase, beta 1 -2.12303
FAM228B family with sequence similarity 228, member B -2.12303
NDC80 NDC80 kinetochore complex component -2.12303
ZNF585A zinc finger protein 585A -2.12303
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C -2.12303
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6 -2.12303
LRSAM1 leucine rich repeat and sterile alpha motif containing 1 -2.12303
MTRF1 mitochondrial translational release factor 1 -2.12303
TK1 thymidine kinase 1, soluble -2.12303
SYT2 synaptotagmin II -2.11526
VPS35L VPS35 endosomal protein sorting factor like -2.11526
DUSP23 dual specificity phosphatase 23 -2.11526
IL4R interleukin 4 receptor -2.11526
ATL1 atlastin GTPase 1 -2.11526
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 -2.11526
TPH2 tryptophan hydroxylase 2 -2.11526
WSCD1 WSC domain containing 1 -2.11526
ZNF507 zinc finger protein 507 -2.11526
EDEM3 ER degradation enhancer, mannosidase alpha-like 3 -2.11526
WBP1 WW domain binding protein 1 -2.11526
MGAT1 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase -2.02988
PIGBOS1 PIGB opposite strand 1 -2.00035
AKIRIN1 akirin 1 -2.00035
GLG1 golgi glycoprotein 1 -2.00035