POP4 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae)|This gene encodes one of the protein subunits of the small nucleolar ribonucleoprotein complexes: the endoribonuclease for mitochondrial RNA processing complex and the ribonuclease P complex. The encoded protein is localized to the nucleus and associates directly with the RNA component of these complexes. This protein is involved in processing of precursor RNAs. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009] (NCBI Entrez Gene Database, 10775)
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Genes

44 genes differentially expressed following the POP4 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 2.88967
MBIP MAP3K12 binding inhibitory protein 1 2.35068
CYTH1 cytohesin 1 2.15294
NT5C 5', 3'-nucleotidase, cytosolic 2.15294
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 2.15294
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 2.15294
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae) 2.15294
FLYWCH2 FLYWCH family member 2 2.15294
MIER3 mesoderm induction early response 1, family member 3 2.15294
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 2.15294
USP40 ubiquitin specific peptidase 40 2.15294
TTC5 tetratricopeptide repeat domain 5 2.15294
SNTG1 syntrophin, gamma 1 2.15294
SDC1 syndecan 1 2.15294
IPMK inositol polyphosphate multikinase 2.15294
WWP2 WW domain containing E3 ubiquitin protein ligase 2 2.15294
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa 2.15294
NOL4L nucleolar protein 4-like 2.15294
SMAD6 SMAD family member 6 2.15294
GNA13 guanine nucleotide binding protein (G protein), alpha 13 2.15294
TRDMT1 tRNA aspartic acid methyltransferase 1 2.15294
TRIM21 tripartite motif containing 21 2.15294
PDGFD platelet derived growth factor D 2.15294
NDUFAF4 NADH dehydrogenase (ubiquinone) complex I, assembly factor 4 2.15294
RMP24 ribonuclease MRP subunit p24 2.15294
FAIM Fas apoptotic inhibitory molecule 2.07811
LRRTM3 leucine rich repeat transmembrane neuronal 3 2.01911

decreased expression

Symbol Name Standardized Value
AKAP9 A kinase (PRKA) anchor protein 9 -2.54749
DSP desmoplakin -2.15294
ATP5PF ATP synthase peripheral stalk subunit F6 -2.15294
SHROOM2 shroom family member 2 -2.15294
ZMAT4 zinc finger, matrin-type 4 -2.15294
SOX5 SRY (sex determining region Y)-box 5 -2.15294
TP53RK TP53 regulating kinase -2.15294
DSTYK dual serine/threonine and tyrosine protein kinase -2.15294
ZNF101 zinc finger protein 101 -2.15294
ELMOD2 ELMO/CED-12 domain containing 2 -2.15294
RPUSD4 RNA pseudouridylate synthase domain containing 4 -2.15294
LLGL2 lethal giant larvae homolog 2 (Drosophila) -2.15294
SH3GLB1 SH3-domain GRB2-like endophilin B1 -2.15294
ENTR1 endosome associated trafficking regulator 1 -2.15294
SPTAN1 spectrin, alpha, non-erythrocytic 1 -2.09226
OLFM2 olfactomedin 2 -2.06102
TENT4B terminal nucleotidyltransferase 4B -2.03283