POP7 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae)| (NCBI Entrez Gene Database, 10248)
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Genes

338 genes differentially expressed following the POP7 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
IZUMO1 izumo sperm-egg fusion 1 2.30632
SCN2A sodium channel, voltage gated, type II alpha subunit 2.30632
SLC46A3 solute carrier family 46, member 3 2.30632
RAI2 retinoic acid induced 2 2.30632
CX3CL1 chemokine (C-X3-C motif) ligand 1 2.30632
ADRB2 adrenoceptor beta 2, surface 2.30632
MUC6 mucin 6, oligomeric mucus/gel-forming 2.30632
NOXO1 NADPH oxidase organizer 1 2.30632
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 2.30632
CDNF cerebral dopamine neurotrophic factor 2.30632
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 2.30632
RUNDC3A RUN domain containing 3A 2.30632
SLC26A4 solute carrier family 26 (anion exchanger), member 4 2.30632
FGF23 fibroblast growth factor 23 2.30632
CPED1 cadherin-like and PC-esterase domain containing 1 2.30632
LBHD1 LBH domain containing 1 2.30632
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A 2.30632
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6 2.30632
GOSR1 golgi SNAP receptor complex member 1 2.30632
KLHL35 kelch-like family member 35 2.30632
ZNF287 zinc finger protein 287 2.30632
RASL10A RAS-like, family 10, member A 2.30632
MYO7A myosin VIIA 2.30632
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 2.30632
FGF20 fibroblast growth factor 20 2.30632
MRPL53 mitochondrial ribosomal protein L53 2.30632
SLC25A45 solute carrier family 25, member 45 2.30632
SFTPB surfactant protein B 2.30632
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 2.30632
GMFG glia maturation factor, gamma 2.30632
KIAA2012 KIAA2012 2.30632
CPB2 carboxypeptidase B2 (plasma) 2.30632
F2 coagulation factor II (thrombin) 2.30632
DPPA3 developmental pluripotency associated 3 2.30632
SUSD5 sushi domain containing 5 2.30632
NPIPA8 nuclear pore complex interacting protein family, member A8 2.30632
GNRHR gonadotropin-releasing hormone receptor 2.30632
CRYGN crystallin, gamma N 2.30632
HAS1 hyaluronan synthase 1 2.30632
CA9 carbonic anhydrase IX 2.30632
FAM131A family with sequence similarity 131, member A 2.30632
PROB1 proline-rich basic protein 1 2.30632
EDEM2 ER degradation enhancer, mannosidase alpha-like 2 2.30632
AADACL4 arylacetamide deacetylase-like 4 2.30632
LRRC56 leucine rich repeat containing 56 2.30632
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4 2.30632
SIKE1 suppressor of IKBKE 1 2.30632
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 2.30632
TNIP2 TNFAIP3 interacting protein 2 2.30632
GYPB glycophorin B (MNS blood group) 2.30632
TRPV3 transient receptor potential cation channel, subfamily V, member 3 2.30632
NFU1 NFU1 iron-sulfur cluster scaffold 2.30632
RPS21-DT RPS21 divergent transcript 2.30632
H4C1 H4 clustered histone 1 2.30632
SELENOI selenoprotein I 2.30632
ELFN2 extracellular leucine-rich repeat and fibronectin type III domain containing 2 2.30632
YPEL4 yippee-like 4 (Drosophila) 2.30632
PNLIPRP2 pancreatic lipase-related protein 2 2.30632
KLB klotho beta 2.30632
IMPG2 interphotoreceptor matrix proteoglycan 2 2.30632
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) 2.30632
FAM107A family with sequence similarity 107, member A 2.30632
NPIPB7 nuclear pore complex interacting protein family, member B7 2.30632
GDF9 growth differentiation factor 9 2.30632
AJM1 apical junction component 1 homolog 2.30632
KASH5 KASH domain containing 5 2.30632
AGA-DT AGA divergent transcript 2.30632
LIPT2-AS1 LIPT2 antisense RNA 1 2.30632
NPIPA6 nuclear pore complex interacting protein family, member A6 2.30632
PNMA8C PNMA family member 8C 2.30632
GNG5B G protein subunit gamma 5B 2.30632
SPAAR small regulatory polypeptide of amino acid response 2.30632
TEX46 testis expressed 46 2.30632
H4C13 H4 clustered histone 13 2.30632
CHCT1 CHD1 helical C-terminal domain containing 1 2.30632
ATP5MGL ATP synthase membrane subunit g like 2.30632
DUSP29 dual specificity phosphatase 29 2.30632
PNPLA1 patatin-like phospholipase domain containing 1 2.30632
STARD6 StAR-related lipid transfer (START) domain containing 6 2.30632
S1PR2 sphingosine-1-phosphate receptor 2 2.30632
CXCL14 chemokine (C-X-C motif) ligand 14 2.30632
UROC1 urocanate hydratase 1 2.30632
MEOX2 mesenchyme homeobox 2 2.30632
SP140 SP140 nuclear body protein 2.30632
COL6A6 collagen, type VI, alpha 6 2.30632
THPO thrombopoietin 2.30632
LTBP2 latent transforming growth factor beta binding protein 2 2.30632
C5ORF58 chromosome 5 open reading frame 58 2.30632
EIF4A1 eukaryotic translation initiation factor 4A1 2.30632
DMP1 dentin matrix acidic phosphoprotein 1 2.30632
TPTE transmembrane phosphatase with tensin homology 2.30632
MIP major intrinsic protein of lens fiber 2.30632
VCX3A variable charge, X-linked 3A 2.30632
VCX3B variable charge, X-linked 3B 2.30632
PGA3 pepsinogen 3, group I (pepsinogen A) 2.30632
UTS2 urotensin 2 2.30632
TACR2 tachykinin receptor 2 2.30632
CLDN22 claudin 22 2.30632
S100P S100 calcium binding protein P 2.30632
C6ORF118 chromosome 6 open reading frame 118 2.30632
C1QL2 complement component 1, q subcomponent-like 2 2.30632
CCK cholecystokinin 2.30632
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 2.30632
CAPN14 calpain 14 2.30632
TMC3 transmembrane channel-like 3 2.30632
MBOAT4 membrane bound O-acyltransferase domain containing 4 2.30632
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 2.30632
OAZ3 ornithine decarboxylase antizyme 3 2.30632
CALHM2 calcium homeostasis modulator 2 2.30632
CD52 CD52 molecule 2.30632
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1 2.30632
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2 2.30632
C22ORF42 chromosome 22 open reading frame 42 2.30632
PCDHGA8 protocadherin gamma subfamily A, 8 2.30632
ZFP92 ZFP92 zinc finger protein 2.30632
ZNF333 zinc finger protein 333 2.30632
KLF5 Kruppel-like factor 5 (intestinal) 2.30632
KLF4 Kruppel-like factor 4 (gut) 2.30632
ANKRD65 ankyrin repeat domain 65 2.30632
PLSCR5 phospholipid scramblase family, member 5 2.30632
ZSCAN4 zinc finger and SCAN domain containing 4 2.30632
NIM1K NIM1 serine/threonine protein kinase 2.30632
CDC20B cell division cycle 20B 2.30632
CERKL ceramide kinase-like 2.30632
EFCAB9 EF-hand calcium binding domain 9 2.30632
DQX1 DEAQ box RNA-dependent ATPase 1 2.30632
SPANXC SPANX family, member C 2.30632
AQP6 aquaporin 6, kidney specific 2.30632
CYP2C18 cytochrome P450, family 2, subfamily C, polypeptide 18 2.30632
RELN reelin 2.30632
CTXN2 cortexin 2 2.30632
CD27 CD27 molecule 2.30632
RGS6 regulator of G-protein signaling 6 2.30632
TMPPE transmembrane protein with metallophosphoesterase domain 2.30632
SH2D1B SH2 domain containing 1B 2.30632
PFN4 profilin family, member 4 2.30632
LRRC25 leucine rich repeat containing 25 2.30632
LGALS14 lectin, galactoside-binding, soluble, 14 2.30632
TSPAN16 tetraspanin 16 2.30632
SPATA16 spermatogenesis associated 16 2.30632
BCL2A1 BCL2-related protein A1 2.30632
PSG7 pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene) 2.30632
ITGA8 integrin, alpha 8 2.30632
BCL2L10 BCL2-like 10 (apoptosis facilitator) 2.30632
ITGA11 integrin, alpha 11 2.30632
MAOB monoamine oxidase B 2.30632
ARL13A ADP-ribosylation factor-like 13A 2.30632
TF transferrin 2.30632
LSMEM2 leucine-rich single-pass membrane protein 2 2.30632
RBM20 RNA binding motif protein 20 2.30632
NT5DC4 5'-nucleotidase domain containing 4 2.30632
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 2.30632
SIGLEC15 sialic acid binding Ig-like lectin 15 2.30632
TPTE2 transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 2.30632
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 2.30632
TTBK1 tau tubulin kinase 1 2.30632
GRAP2 GRB2-related adaptor protein 2 2.30632
GPRASP1 G protein-coupled receptor associated sorting protein 1 2.30632
GGN gametogenetin 2.30632
RAB7B RAB7B, member RAS oncogene family 2.30632
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 2.30632
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria 2.30632
ANGPTL3 angiopoietin-like 3 2.30632
SHBG sex hormone-binding globulin 2.30632
GREM1 gremlin 1, DAN family BMP antagonist 2.30632
PM20D1 peptidase M20 domain containing 1 2.30632
EPN2 epsin 2 2.30632
ANKRD30A ankyrin repeat domain 30A 2.30632
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) 2.30632
CCR10 chemokine (C-C motif) receptor 10 2.30632
OVCH2 ovochymase 2 (gene/pseudogene) 2.30632
LDHC lactate dehydrogenase C 2.30632
CSNK2A3 casein kinase 2, alpha 3 polypeptide 2.30632
NWD2 NACHT and WD repeat domain containing 2 2.30632
CENPM centromere protein M 2.30632
FGF6 fibroblast growth factor 6 2.30632
BTBD19 BTB (POZ) domain containing 19 2.30632
PODN podocan 2.30632
ECHS1 enoyl CoA hydratase, short chain, 1, mitochondrial 2.30632
GK glycerol kinase 2.30632
APOL6 apolipoprotein L, 6 2.30632
STMND1 stathmin domain containing 1 2.30632
SLITRK1 SLIT and NTRK-like family, member 1 2.30632
ACTR3C ARP3 actin-related protein 3 homolog C (yeast) 2.30632
PSORS1C1 psoriasis susceptibility 1 candidate 1 2.30632
AGGF1 angiogenic factor with G patch and FHA domains 1 2.30632
HSPB9 heat shock protein, alpha-crystallin-related, B9 2.30632
DAND5 DAN domain family member 5, BMP antagonist 2.30632
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6 2.30632
PHOSPHO1 phosphatase, orphan 1 2.30632
ALDH1L1 aldehyde dehydrogenase 1 family, member L1 2.30632
ZMYND15 zinc finger, MYND-type containing 15 2.30632
FAM25G family with sequence similarity 25, member G 2.30632
PHPT1 phosphohistidine phosphatase 1 2.27872
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 2.26859
SOD2 superoxide dismutase 2, mitochondrial 2.25847
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16 2.23885
TTC23 tetratricopeptide repeat domain 23 2.20048
ZNF468 zinc finger protein 468 2.18867
TMEM131L transmembrane 131 like 2.18524
PAGR1 PAXIP1 associated glutamate-rich protein 1 2.18524
TMEM200C transmembrane protein 200C 2.18524
TSLIG3C tRNA splicing ligase complex subunit 3C 2.18524
ACSL6 acyl-CoA synthetase long-chain family member 6 2.18524
TARBP2 TAR (HIV-1) RNA binding protein 2 2.18524
MT1M metallothionein 1M 2.18524
TECPR1 tectonin beta-propeller repeat containing 1 2.18524
SAE1 SUMO1 activating enzyme subunit 1 2.18524
CSTPP1 centriolar satellite-associated tubulin polyglutamylase complex regulator 1 2.17494
NME4 NME/NM23 nucleoside diphosphate kinase 4 2.16984
SPATA2 spermatogenesis associated 2 2.14215
SYPL1 synaptophysin-like 1 2.09905
USP15 ubiquitin specific peptidase 15 2.0896
RAD23B RAD23 homolog B (S. cerevisiae) 2.08861
ATG13 autophagy related 13 2.08771
TTPAL tocopherol (alpha) transfer protein-like 2.08771
AIMP1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 2.07718
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) 2.07718
SYCP2L synaptonemal complex protein 2-like 2.07718
ANKIB1 ankyrin repeat and IBR domain containing 1 2.06984
RAD50 RAD50 homolog (S. cerevisiae) 2.04181
ZNF787 zinc finger protein 787 2.02798
NOL9 nucleolar protein 9 2.02798
AHR aryl hydrocarbon receptor 2.02798
DMAP1 DNA methyltransferase 1 associated protein 1 2.01205

decreased expression

Symbol Name Standardized Value
HMGA2 high mobility group AT-hook 2 -2.30632
NR4A1 nuclear receptor subfamily 4, group A, member 1 -2.30632
ZNF260 zinc finger protein 260 -2.30632
PTPN3 protein tyrosine phosphatase, non-receptor type 3 -2.30632
SFPQ splicing factor proline/glutamine-rich -2.30632
TMEM114 transmembrane protein 114 -2.30632
FNDC3A fibronectin type III domain containing 3A -2.30632
ZSCAN2 zinc finger and SCAN domain containing 2 -2.30632
CLCN2 chloride channel, voltage-sensitive 2 -2.30632
SOAT1 sterol O-acyltransferase 1 -2.30632
PEX3 peroxisomal biogenesis factor 3 -2.30632
LCMT2 leucine carboxyl methyltransferase 2 -2.30632
HOMER3 homer scaffolding protein 3 -2.30632
ZNF646 zinc finger protein 646 -2.30632
MTDH metadherin -2.30632
ZNF816 zinc finger protein 816 -2.30632
SLC26A6 solute carrier family 26 (anion exchanger), member 6 -2.30632
DCAKD dephospho-CoA kinase domain containing -2.30632
NECAB2 N-terminal EF-hand calcium binding protein 2 -2.30632
EYA2 EYA transcriptional coactivator and phosphatase 2 -2.30632
EP400 E1A binding protein p400 -2.30632
LMLN leishmanolysin-like (metallopeptidase M8 family) -2.30632
SMTNL2 smoothelin-like 2 -2.30632
ODAD3 outer dynein arm docking complex subunit 3 -2.30632
GADD45B growth arrest and DNA-damage-inducible, beta -2.30632
SIRT1 sirtuin 1 -2.30632
EBNA1BP2 EBNA1 binding protein 2 -2.30632
FAM151B family with sequence similarity 151, member B -2.30632
SMIM14 small integral membrane protein 14 -2.30632
NUDT8 nudix (nucleoside diphosphate linked moiety X)-type motif 8 -2.30632
SCARF2 scavenger receptor class F, member 2 -2.30632
ADAM15 ADAM metallopeptidase domain 15 -2.30632
ZNF419 zinc finger protein 419 -2.30632
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -2.30632
ZNF699 zinc finger protein 699 -2.30632
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) -2.30632
GJC1 gap junction protein, gamma 1, 45kDa -2.30632
AOX1 aldehyde oxidase 1 -2.30632
OTUD1 OTU deubiquitinase 1 -2.30632
KIF13A kinesin family member 13A -2.30632
SYDE2 synapse defective 1, Rho GTPase, homolog 2 (C. elegans) -2.29201
SNX11 sorting nexin 11 -2.27948
RIT2 Ras-like without CAAX 2 -2.27948
SCAND3 SCAN domain containing 3 -2.27948
GJB7 gap junction protein, beta 7, 25kDa -2.27948
NFIC nuclear factor I/C (CCAAT-binding transcription factor) -2.23956
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -2.23052
FDX2 ferredoxin 2 -2.20048
SNN stannin -2.19887
EHD2 EH-domain containing 2 -2.19887
RPRD2 regulation of nuclear pre-mRNA domain containing 2 -2.19306
SLC6A16 solute carrier family 6, member 16 -2.19306
SPTBN1 spectrin, beta, non-erythrocytic 1 -2.19014
IRF7 interferon regulatory factor 7 -2.18524
FYB2 FYN binding protein 2 -2.18524
KY kyphoscoliosis peptidase -2.18524
LEAP2 liver expressed antimicrobial peptide 2 -2.18524
ACSL1 acyl-CoA synthetase long-chain family member 1 -2.18524
ACTL6B actin-like 6B -2.18524
PRDM7 PR domain containing 7 -2.18524
KIRREL1 kirre like nephrin family adhesion molecule 1 -2.18524
HCFC2 host cell factor C2 -2.18524
VSTM2B V-set and transmembrane domain containing 2B -2.18524
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1 -2.18524
IRF4 interferon regulatory factor 4 -2.18524
HRH3 histamine receptor H3 -2.18524
TMEM191C transmembrane protein 191C -2.18524
SPRYD3 SPRY domain containing 3 -2.18524
HHIPL1 HHIP-like 1 -2.18524
PTGDS prostaglandin D2 synthase 21kDa (brain) -2.18524
PTGDR prostaglandin D2 receptor (DP) -2.18524
RPGRIP1 retinitis pigmentosa GTPase regulator interacting protein 1 -2.18524
NGF nerve growth factor (beta polypeptide) -2.18524
RGS11 regulator of G-protein signaling 11 -2.18524
PEBP4 phosphatidylethanolamine-binding protein 4 -2.18524
C2CD4C C2 calcium-dependent domain containing 4C -2.18524
CEL carboxyl ester lipase -2.18524
PYGO1 pygopus family PHD finger 1 -2.18524
GPHA2 glycoprotein hormone alpha 2 -2.18524
MAGEL2 melanoma antigen family L2 -2.18524
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2 -2.18524
RGL4 ral guanine nucleotide dissociation stimulator-like 4 -2.18524
ICAM5 intercellular adhesion molecule 5, telencephalin -2.18524
SMCO2 single-pass membrane protein with coiled-coil domains 2 -2.18524
RAMP1 receptor (G protein-coupled) activity modifying protein 1 -2.18524
C2CD2L C2CD2-like -2.18524
ZNF404 zinc finger protein 404 -2.18524
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal) -2.18524
STAG1 stromal antigen 1 -2.18524
RRBP1 ribosome binding protein 1 -2.18064
NOS1 nitric oxide synthase 1 (neuronal) -2.16984
MMP25 matrix metallopeptidase 25 -2.16984
MMADHC methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria -2.13148
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 -2.1272
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 -2.12179
TAC1 tachykinin, precursor 1 -2.11336
SERINC5 serine incorporator 5 -2.09473
DNM1L dynamin 1-like -2.09277
SOX11 SRY (sex determining region Y)-box 11 -2.0896
PRPF6 pre-mRNA processing factor 6 -2.08771
CCDC144A coiled-coil domain containing 144A -2.08644
PAK5 p21 (RAC1) activated kinase 5 -2.07718
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -2.07718
FOXP1 forkhead box P1 -2.07718
LETM2 leucine zipper-EF-hand containing transmembrane protein 2 -2.07123
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1 -2.07123
WDR59 WD repeat domain 59 -2.06765
PPCS phosphopantothenoylcysteine synthetase -2.06178
BAALC brain and acute leukemia, cytoplasmic -2.05627
NUB1 negative regulator of ubiquitin-like proteins 1 -2.04211
PI4KB phosphatidylinositol 4-kinase, catalytic, beta -2.02798
TGFA transforming growth factor, alpha -2.00629
OTOG otogelin -2.00629