| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | porcupine homolog (Drosophila)|This gene belongs to the evolutionarily conserved porcupine (Porc) gene family. Genes of the porcupine family encode endoplasmic reticulum proteins with multiple transmembrane domains. Porcupine proteins are involved in the processing of Wnt (wingless and int homologue) proteins. Disruption of this gene is associated with focal dermal hypoplasia, and the encoded protein has been implicated in cancer. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Aug 2013] (NCBI Entrez Gene Database, 64840) |
| External Link | https://ncbi.nlm.nih.gov/gene/64840 |
| Similar Terms | |
| Downloads & Tools |
496 genes differentially expressed following the PORCN gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PCNA | proliferating cell nuclear antigen | 0.0186931 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0159462 |
| PROM1 | prominin 1 | 0.0137076 |
| TBX2 | T-box 2 | 0.0124998 |
| CNPY3 | canopy FGF signaling regulator 3 | 0.0113158 |
| ADM | adrenomedullin | 0.0112469 |
| MEF2C | myocyte enhancer factor 2C | 0.0105818 |
| TNC | tenascin C | 0.0104271 |
| PADI2 | peptidyl arginine deiminase, type II | 0.0102533 |
| HOPX | HOP homeobox | 0.0102393 |
| NEFH | neurofilament, heavy polypeptide | 0.0101882 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0100066 |
| CHI3L2 | chitinase 3-like 2 | 0.00997804 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.00996483 |
| KYNU | kynureninase | 0.00991621 |
| KRT7 | keratin 7, type II | 0.0098987 |
| BID | BH3 interacting domain death agonist | 0.00986314 |
| IFI44L | interferon-induced protein 44-like | 0.00966273 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.00956646 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.00949769 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | 0.00944285 |
| NTS | neurotensin | 0.00943954 |
| EFHD1 | EF-hand domain family, member D1 | 0.00938509 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | 0.00932286 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | 0.00920172 |
| KRT81 | keratin 81, type II | 0.00910433 |
| PLK1 | polo-like kinase 1 | 0.00909229 |
| RCAN1 | regulator of calcineurin 1 | 0.00908865 |
| TPM2 | tropomyosin 2 (beta) | 0.00906309 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta | 0.0090018 |
| VSNL1 | visinin-like 1 | 0.00885726 |
| LXN | latexin | 0.00880457 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 | 0.00856874 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.00855351 |
| CYBA | cytochrome b-245, alpha polypeptide | 0.00854057 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.00847014 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | 0.00842353 |
| IFI44 | interferon-induced protein 44 | 0.00840399 |
| PIP | prolactin-induced protein | 0.0082205 |
| RGS10 | regulator of G-protein signaling 10 | 0.00816314 |
| LY75 | lymphocyte antigen 75 | 0.00805308 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | 0.00802147 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | 0.0080057 |
| PAMR1 | peptidase domain containing associated with muscle regeneration 1 | 0.00796596 |
| CYB5R2 | cytochrome b5 reductase 2 | 0.0079207 |
| CDCA4 | cell division cycle associated 4 | 0.00787824 |
| FABP7 | fatty acid binding protein 7, brain | 0.00765132 |
| AQP4 | aquaporin 4 | 0.00759494 |
| NPR3 | natriuretic peptide receptor 3 | 0.00745439 |
| STAC | SH3 and cysteine rich domain | 0.00745429 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.0074397 |
| NEBL | nebulette | 0.00742213 |
| MX1 | MX dynamin-like GTPase 1 | 0.00738673 |
| LBH | limb bud and heart development | 0.0073439 |
| HBD | hemoglobin, delta | 0.00733196 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | 0.00727363 |
| LRRN3 | leucine rich repeat neuronal 3 | 0.00724283 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | 0.00720434 |
| PLIN3 | perilipin 3 | 0.00712153 |
| EVI2A | ecotropic viral integration site 2A | 0.00706927 |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) | 0.007069 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.00706427 |
| PLK2 | polo-like kinase 2 | 0.00705399 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.00702285 |
| INHBB | inhibin, beta B | 0.0070189 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.00698196 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.00694649 |
| ARMCX2 | armadillo repeat containing, X-linked 2 | 0.00690935 |
| EFNB2 | ephrin-B2 | 0.00689316 |
| ANO10 | anoctamin 10 | 0.00687529 |
| ANXA6 | annexin A6 | 0.00685456 |
| DDX11 | DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 | 0.00683462 |
| WIF1 | WNT inhibitory factor 1 | 0.00682544 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 | 0.00681659 |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 | 0.00679324 |
| NOTCH3 | notch 3 | 0.00677907 |
| AK5 | adenylate kinase 5 | 0.00674747 |
| CHGB | chromogranin B | 0.00673527 |
| HEBP2 | heme binding protein 2 | 0.00673153 |
| IVNS1ABP | influenza virus NS1A binding protein | 0.00671958 |
| RTN2 | reticulon 2 | 0.00671461 |
| CYP26B1 | cytochrome P450, family 26, subfamily B, polypeptide 1 | 0.00669593 |
| CYRIA | CYFIP related Rac1 interactor A | 0.00667764 |
| NME4 | NME/NM23 nucleoside diphosphate kinase 4 | 0.00667316 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.00666964 |
| CCK | cholecystokinin | 0.0066664 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | 0.00665423 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.00664161 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.00663852 |
| DAXX | death-domain associated protein | 0.0066297 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 0.00655619 |
| SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 | 0.00654098 |
| SMOX | spermine oxidase | 0.00652781 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0065259 |
| SYT1 | synaptotagmin I | 0.00652272 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | 0.00649776 |
| LTF | lactotransferrin | 0.00648167 |
| RGCC | regulator of cell cycle | 0.00645188 |
| STMN2 | stathmin 2 | 0.00644382 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 | 0.00633407 |
| MYBPC1 | myosin binding protein C, slow type | 0.00631311 |
| TMEM47 | transmembrane protein 47 | 0.00625939 |
| CLDN10 | claudin 10 | 0.00624092 |
| NCAN | neurocan | 0.00624082 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | 0.00622586 |
| KLK6 | kallikrein-related peptidase 6 | 0.00622556 |
| DPYSL4 | dihydropyrimidinase-like 4 | 0.00619835 |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) | 0.00619623 |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 | 0.00619576 |
| IQCG | IQ motif containing G | 0.00618252 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.00616681 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | 0.00616388 |
| CHMP5 | charged multivesicular body protein 5 | 0.00615688 |
| FGF13 | fibroblast growth factor 13 | 0.00614659 |
| TMEM243 | transmembrane protein 243, mitochondrial | 0.00614443 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.00609265 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 0.00604484 |
| OXTR | oxytocin receptor | 0.00604185 |
| VLDLR | very low density lipoprotein receptor | 0.00603643 |
| PLPP3 | phospholipid phosphatase 3 | 0.00602538 |
| PRKCQ | protein kinase C, theta | 0.00601882 |
| ZMAT3 | zinc finger, matrin-type 3 | 0.0060128 |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 | 0.00599958 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | 0.00598156 |
| FXYD5 | FXYD domain containing ion transport regulator 5 | 0.00597365 |
| FHL1 | four and a half LIM domains 1 | 0.00593522 |
| SALL1 | spalt-like transcription factor 1 | 0.00591676 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.00589603 |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 | 0.00589282 |
| TXNDC9 | thioredoxin domain containing 9 | 0.00588397 |
| PLCD1 | phospholipase C, delta 1 | 0.00588052 |
| CCNB1IP1 | cyclin B1 interacting protein 1, E3 ubiquitin protein ligase | 0.00587727 |
| PIN1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 | 0.00587164 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 | 0.00586476 |
| LRP2 | low density lipoprotein receptor-related protein 2 | 0.00586432 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.00585382 |
| S100A9 | S100 calcium binding protein A9 | 0.00583781 |
| TRIM2 | tripartite motif containing 2 | 0.00583367 |
| STC1 | stanniocalcin 1 | 0.00579812 |
| S100A7 | S100 calcium binding protein A7 | 0.00578913 |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) | 0.00576837 |
| CYB561 | cytochrome b561 | 0.00575401 |
| GPR37 | G protein-coupled receptor 37 (endothelin receptor type B-like) | 0.00574169 |
| CXADR | coxsackie virus and adenovirus receptor | 0.00572122 |
| ATRN | attractin | 0.00571124 |
| ANXA2 | annexin A2 | 0.0056947 |
| DNTT | DNA nucleotidylexotransferase | 0.00568806 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 | 0.00568469 |
| SNX5 | sorting nexin 5 | 0.00568188 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | 0.0056545 |
| CD59 | CD59 molecule, complement regulatory protein | 0.00564492 |
| BAALC | brain and acute leukemia, cytoplasmic | 0.0056057 |
| GSTO1 | glutathione S-transferase omega 1 | 0.00560248 |
| DUSP2 | dual specificity phosphatase 2 | 0.00558901 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.00558442 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 0.00557656 |
| GLIPR1 | GLI pathogenesis-related 1 | 0.0055698 |
| SMAD3 | SMAD family member 3 | 0.00555921 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | 0.00554829 |
| DHCR7 | 7-dehydrocholesterol reductase | 0.00554327 |
| LEPR | leptin receptor | 0.00553209 |
| TSPAN5 | tetraspanin 5 | 0.00550576 |
| GALC | galactosylceramidase | 0.00547951 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | 0.00546943 |
| TIMM8B | translocase of inner mitochondrial membrane 8 homolog B (yeast) | 0.00546735 |
| SLC35G2 | solute carrier family 35, member G2 | 0.0054669 |
| STC2 | stanniocalcin 2 | 0.00546138 |
| CA11 | carbonic anhydrase XI | 0.00544715 |
| GLRB | glycine receptor, beta | 0.00542319 |
| KRT23 | keratin 23, type I | 0.00541844 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.00539153 |
| SELENOW | selenoprotein W | 0.00538095 |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 | 0.00536795 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 | 0.00536574 |
| MAB21L1 | mab-21-like 1 (C. elegans) | 0.0053623 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.00535946 |
| VNN1 | vanin 1 | 0.00534723 |
| HIST1H2AC | histone cluster 1, H2ac | 0.005319 |
| TAGLN3 | transgelin 3 | 0.00531807 |
| NES | nestin | 0.005317 |
| NUDT11 | nudix (nucleoside diphosphate linked moiety X)-type motif 11 | 0.00531649 |
| NPY | neuropeptide Y | 0.00531052 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | 0.00530703 |
| ELK3 | ELK3, ETS-domain protein (SRF accessory protein 2) | 0.00530595 |
| COG7 | component of oligomeric golgi complex 7 | 0.00530277 |
| VEGFA | vascular endothelial growth factor A | 0.00529792 |
| ANXA2P2 | annexin A2 pseudogene 2 | 0.00529353 |
| ANGPT1 | angiopoietin 1 | 0.00527844 |
| ITGA4 | integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) | 0.00526636 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | 0.00525465 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.00524105 |
| RPP40 | ribonuclease P/MRP 40kDa subunit | 0.0052347 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 0.00522608 |
| LY86 | lymphocyte antigen 86 | 0.00521897 |
| FST | follistatin | 0.00521841 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | 0.00521314 |
| HAUS4 | HAUS augmin-like complex, subunit 4 | 0.00520747 |
| TPM4 | tropomyosin 4 | 0.00520668 |
| HMGA1 | high mobility group AT-hook 1 | 0.0052038 |
| CDHR1 | cadherin-related family member 1 | 0.00520208 |
| ESRRG | estrogen-related receptor gamma | 0.00513967 |
| ACOX3 | acyl-CoA oxidase 3, pristanoyl | 0.00513662 |
| MICA | MHC class I polypeptide-related sequence A | 0.00512349 |
| SNAPC1 | small nuclear RNA activating complex, polypeptide 1, 43kDa | 0.00510786 |
| C3ORF14 | chromosome 3 open reading frame 14 | 0.00510563 |
| ZIC1 | Zic family member 1 | 0.00509675 |
| TESC | tescalcin | 0.00509428 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.0050803 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | 0.00507847 |
| NRGN | neurogranin (protein kinase C substrate, RC3) | 0.00507836 |
| ASTN2 | astrotactin 2 | 0.00506226 |
| BDNF | brain-derived neurotrophic factor | 0.00506138 |
| TMEM100 | transmembrane protein 100 | 0.00505201 |
| IPCEF1 | interaction protein for cytohesin exchange factors 1 | 0.00504678 |
| KDM5A | lysine (K)-specific demethylase 5A | 0.00503332 |
| SYNJ2 | synaptojanin 2 | 0.00503292 |
| IL1RN | interleukin 1 receptor antagonist | 0.00502607 |
| ARPC5 | actin related protein 2/3 complex, subunit 5, 16kDa | 0.00502547 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.00501808 |
| HMP19 | HMP19 protein | 0.00500226 |
| SCARA3 | scavenger receptor class A, member 3 | 0.0049918 |
| LDB2 | LIM domain binding 2 | 0.00499177 |
| ICAM2 | intercellular adhesion molecule 2 | 0.00498612 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | 0.00498407 |
| GPC1 | glypican 1 | 0.00497804 |
| GTPBP8 | GTP-binding protein 8 (putative) | 0.00497785 |
| ALPL | alkaline phosphatase, liver/bone/kidney | 0.00496834 |
| DOK5 | docking protein 5 | 0.00496328 |
| DUSP5 | dual specificity phosphatase 5 | 0.00495783 |
| MRPS16 | mitochondrial ribosomal protein S16 | 0.00495729 |
| UST | uronyl-2-sulfotransferase | 0.00494998 |
| RMND1 | required for meiotic nuclear division 1 homolog (S. cerevisiae) | 0.00494376 |
| S100A8 | S100 calcium binding protein A8 | 0.00493755 |
| CLEC11A | C-type lectin domain family 11, member A | 0.00492965 |
| DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 | 0.00491914 |
| FGF1 | fibroblast growth factor 1 (acidic) | 0.00491523 |
| INSL4 | insulin-like 4 (placenta) | 0.00491116 |
| OLFML3 | olfactomedin-like 3 | 0.00490487 |
| GCLM | glutamate-cysteine ligase, modifier subunit | 0.00490361 |
| KLF10 | Kruppel-like factor 10 | 0.00489816 |
| GDI2 | GDP dissociation inhibitor 2 | 0.00487199 |
| CLU | clusterin | 0.00486942 |
| KRT15 | keratin 15, type I | 0.00486188 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0048385 |
| PHF11 | PHD finger protein 11 | 0.00483487 |
| ITPA | inosine triphosphatase (nucleoside triphosphate pyrophosphatase) | 0.00483035 |
| SEC14L2 | SEC14-like 2 (S. cerevisiae) | 0.00482868 |
| PITX3 | paired-like homeodomain 3 | 0.00482653 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CHP1 | calcineurin-like EF-hand protein 1 | -0.0177035 |
| MAGEA3 | melanoma antigen family A3 | -0.017512 |
| ASPN | asporin | -0.0146185 |
| AEBP1 | AE binding protein 1 | -0.0134809 |
| FABP4 | fatty acid binding protein 4, adipocyte | -0.0134143 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.0130335 |
| LEF1 | lymphoid enhancer-binding factor 1 | -0.0117979 |
| C1R | complement component 1, r subcomponent | -0.0116192 |
| F13A1 | coagulation factor XIII, A1 polypeptide | -0.0115506 |
| CTSK | cathepsin K | -0.0114699 |
| METTL7A | methyltransferase like 7A | -0.0109641 |
| CD163 | CD163 molecule | -0.0109194 |
| MAGEA12 | melanoma antigen family A12 | -0.0106706 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0105297 |
| GPNMB | glycoprotein (transmembrane) nmb | -0.0103967 |
| TMEM176B | transmembrane protein 176B | -0.0103073 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | -0.0102851 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0102793 |
| WT1 | Wilms tumor 1 | -0.0102254 |
| KRT18 | keratin 18, type I | -0.0101807 |
| EPCAM | epithelial cell adhesion molecule | -0.00996381 |
| DCN | decorin | -0.00992951 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -0.00991846 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | -0.00991794 |
| FRS2 | fibroblast growth factor receptor substrate 2 | -0.0098156 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 | -0.0098123 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.00958871 |
| FBLN1 | fibulin 1 | -0.00957774 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.00951976 |
| COL14A1 | collagen, type XIV, alpha 1 | -0.00951816 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 | -0.00947086 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase | -0.00930936 |
| STIP1 | stress-induced phosphoprotein 1 | -0.00927512 |
| COMP | cartilage oligomeric matrix protein | -0.00918895 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.00868768 |
| TPSAB1 | tryptase alpha/beta 1 | -0.00858952 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | -0.00856504 |
| TPD52 | tumor protein D52 | -0.0085447 |
| COL15A1 | collagen, type XV, alpha 1 | -0.00845516 |
| PDGFRL | platelet-derived growth factor receptor-like | -0.00843512 |
| WBP5 | WW domain binding protein 5 | -0.00842214 |
| PLA1A | phospholipase A1 member A | -0.00841805 |
| C1QA | complement component 1, q subcomponent, A chain | -0.00836756 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | -0.00830624 |
| SNX10 | sorting nexin 10 | -0.00815344 |
| IRS2 | insulin receptor substrate 2 | -0.00808474 |
| C3 | complement component 3 | -0.00804624 |
| MFAP2 | microfibrillar-associated protein 2 | -0.0080204 |
| MITF | microphthalmia-associated transcription factor | -0.00799864 |
| BTG2 | BTG family, member 2 | -0.00798093 |
| MMP2 | matrix metallopeptidase 2 | -0.00792296 |
| HSPA1A | heat shock 70kDa protein 1A | -0.00785802 |
| OGN | osteoglycin | -0.00778385 |
| NOTCH2 | notch 2 | -0.0077497 |
| COL11A1 | collagen, type XI, alpha 1 | -0.00771539 |
| C1S | complement component 1, s subcomponent | -0.00770579 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 | -0.00768624 |
| GCH1 | GTP cyclohydrolase 1 | -0.00764001 |
| MMP13 | matrix metallopeptidase 13 | -0.00754667 |
| MFAP5 | microfibrillar associated protein 5 | -0.00750147 |
| C1QB | complement component 1, q subcomponent, B chain | -0.00748347 |
| ESRP1 | epithelial splicing regulatory protein 1 | -0.00748328 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.00742689 |
| RNF19B | ring finger protein 19B | -0.0074228 |
| LRRC15 | leucine rich repeat containing 15 | -0.00739971 |
| GDF15 | growth differentiation factor 15 | -0.00739603 |
| ISLR | immunoglobulin superfamily containing leucine-rich repeat | -0.00738156 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.00737266 |
| PEG10 | paternally expressed 10 | -0.00730652 |
| ALOX5 | arachidonate 5-lipoxygenase | -0.00730138 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 | -0.00729602 |
| SNAI2 | snail family zinc finger 2 | -0.00729252 |
| ITGA6 | integrin, alpha 6 | -0.00723305 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.00721522 |
| WISP2 | WNT1 inducible signaling pathway protein 2 | -0.00717906 |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) | -0.00717799 |
| CLGN | calmegin | -0.00716525 |
| CCP110 | centriolar coiled coil protein 110kDa | -0.0071421 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | -0.00713315 |
| COL5A1 | collagen, type V, alpha 1 | -0.0071205 |
| MCOLN3 | mucolipin 3 | -0.00711169 |
| ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A | -0.00710465 |
| PJA1 | praja ring finger 1, E3 ubiquitin protein ligase | -0.00709797 |
| STK10 | serine/threonine kinase 10 | -0.00707595 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 | -0.00703517 |
| TFF3 | trefoil factor 3 (intestinal) | -0.00702533 |
| CFD | complement factor D (adipsin) | -0.00701602 |
| SOBP | sine oculis binding protein homolog (Drosophila) | -0.00701522 |
| APOA1 | apolipoprotein A-I | -0.00698962 |
| ARG2 | arginase 2 | -0.006971 |
| FADS3 | fatty acid desaturase 3 | -0.00693409 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | -0.00691754 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog | -0.0069062 |
| RXRA | retinoid X receptor, alpha | -0.00690509 |
| THBS4 | thrombospondin 4 | -0.00689376 |
| MAOA | monoamine oxidase A | -0.00684348 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.00678365 |
| HERC2 | HECT and RLD domain containing E3 ubiquitin protein ligase 2 | -0.00676289 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.00675585 |
| BCHE | butyrylcholinesterase | -0.00673319 |
| TGOLN2 | trans-golgi network protein 2 | -0.00673194 |
| LUM | lumican | -0.00670945 |
| CPT1A | carnitine palmitoyltransferase 1A (liver) | -0.00670127 |
| GMPR | guanosine monophosphate reductase | -0.00667406 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | -0.00665474 |
| SERINC5 | serine incorporator 5 | -0.0066492 |
| ANXA4 | annexin A4 | -0.00662417 |
| VCAM1 | vascular cell adhesion molecule 1 | -0.00661432 |
| NPL | N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) | -0.00659567 |
| TSPAN8 | tetraspanin 8 | -0.00658061 |
| TAX1BP3 | Tax1 (human T-cell leukemia virus type I) binding protein 3 | -0.0065805 |
| SPON2 | spondin 2, extracellular matrix protein | -0.0065734 |
| GOLM1 | golgi membrane protein 1 | -0.00652342 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | -0.00650456 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | -0.00650408 |
| CHD7 | chromodomain helicase DNA binding protein 7 | -0.00650048 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0064787 |
| WDR13 | WD repeat domain 13 | -0.00647536 |
| CCL8 | chemokine (C-C motif) ligand 8 | -0.00645581 |
| SGCE | sarcoglycan, epsilon | -0.00644251 |
| TPP1 | tripeptidyl peptidase I | -0.00638631 |
| FBLN5 | fibulin 5 | -0.00638617 |
| PRAME | preferentially expressed antigen in melanoma | -0.00637503 |
| RNF130 | ring finger protein 130 | -0.00636794 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | -0.0063609 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | -0.00636024 |
| AMDHD2 | amidohydrolase domain containing 2 | -0.00635938 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | -0.00632402 |
| FMOD | fibromodulin | -0.00631567 |
| SRPX | sushi-repeat containing protein, X-linked | -0.00630959 |
| CCL19 | chemokine (C-C motif) ligand 19 | -0.00630127 |
| VSIG4 | V-set and immunoglobulin domain containing 4 | -0.00629114 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | -0.0062878 |
| COL16A1 | collagen, type XVI, alpha 1 | -0.00628418 |
| FAM120A | family with sequence similarity 120A | -0.00628108 |
| ABHD3 | abhydrolase domain containing 3 | -0.00626653 |
| CPA3 | carboxypeptidase A3 (mast cell) | -0.00625277 |
| CDV3 | CDV3 homolog (mouse) | -0.00624599 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.00624002 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.00623241 |
| HIRA | histone cell cycle regulator | -0.00622921 |
| NADK | NAD kinase | -0.00621143 |
| PMEL | premelanosome protein | -0.00621111 |
| MFSD12 | major facilitator superfamily domain containing 12 | -0.00620999 |
| CLDN3 | claudin 3 | -0.006202 |
| SFRP4 | secreted frizzled-related protein 4 | -0.00618881 |
| EIF5A | eukaryotic translation initiation factor 5A | -0.00616665 |
| MEIS2 | Meis homeobox 2 | -0.00613535 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.00611465 |
| GNAS | GNAS complex locus | -0.0060863 |
| SNAP23 | synaptosomal-associated protein, 23kDa | -0.00608262 |
| C1RL | complement component 1, r subcomponent-like | -0.00607702 |
| LINC00623 | long intergenic non-protein coding RNA 623 | -0.0060681 |
| MGRN1 | mahogunin ring finger 1, E3 ubiquitin protein ligase | -0.00605833 |
| ANK2 | ankyrin 2, neuronal | -0.00605552 |
| STAB1 | stabilin 1 | -0.00604436 |
| A2M | alpha-2-macroglobulin | -0.00604174 |
| DPT | dermatopontin | -0.00601386 |
| MFAP4 | microfibrillar-associated protein 4 | -0.00598242 |
| PMP22 | peripheral myelin protein 22 | -0.0059464 |
| APOB | apolipoprotein B | -0.00594017 |
| BCL2L2 | BCL2-like 2 | -0.00593768 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.00592416 |
| SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 | -0.005916 |
| HOXB6 | homeobox B6 | -0.00590663 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.00590021 |
| FABP1 | fatty acid binding protein 1, liver | -0.00589195 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | -0.0058758 |
| KRT8 | keratin 8, type II | -0.00586872 |
| PLN | phospholamban | -0.00586744 |
| ZBTB16 | zinc finger and BTB domain containing 16 | -0.00585128 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | -0.00583821 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | -0.00583081 |
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4A | -0.00582915 |
| OTULINL | OTU deubiquitinase with linear linkage specificity like | -0.00582118 |
| LAMP1 | lysosomal-associated membrane protein 1 | -0.00576274 |
| CLEC2B | C-type lectin domain family 2, member B | -0.00576095 |
| PRRC2C | proline-rich coiled-coil 2C | -0.00574977 |
| PAEP | progestagen-associated endometrial protein | -0.00572373 |
| PRDX6 | peroxiredoxin 6 | -0.00572211 |
| MAGEA4 | melanoma antigen family A4 | -0.00566782 |
| MAGEA1 | melanoma antigen family A1 | -0.00566618 |
| ABAT | 4-aminobutyrate aminotransferase | -0.00565069 |
| TSC2 | tuberous sclerosis 2 | -0.00562956 |
| CD209 | CD209 molecule | -0.00562206 |
| STXBP1 | syntaxin binding protein 1 | -0.00561499 |
| C4ORF19 | chromosome 4 open reading frame 19 | -0.00561427 |
| FBN1 | fibrillin 1 | -0.00557512 |
| PRUNE2 | prune homolog 2 (Drosophila) | -0.00556925 |
| NUAK1 | NUAK family, SNF1-like kinase, 1 | -0.00556647 |
| KANK2 | KN motif and ankyrin repeat domains 2 | -0.00556376 |
| MLXIP | MLX interacting protein | -0.00555497 |
| EGFL6 | EGF-like-domain, multiple 6 | -0.00554943 |
| ZNF106 | zinc finger protein 106 | -0.00554212 |
| DSP | desmoplakin | -0.00551447 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.00551027 |
| MLANA | melan-A | -0.00550389 |
| GANAB | glucosidase, alpha; neutral AB | -0.00547797 |
| ALB | albumin | -0.00547751 |
| NMU | neuromedin U | -0.00547611 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -0.00547242 |
| C1ORF56 | chromosome 1 open reading frame 56 | -0.0054719 |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous | -0.00546153 |
| SULT1A1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 | -0.00545555 |
| NELFCD | negative elongation factor complex member C/D | -0.00543995 |
| SEPHS2 | selenophosphate synthetase 2 | -0.005433 |
| PLEKHM1 | pleckstrin homology domain containing, family M (with RUN domain) member 1 | -0.00541998 |
| PRSS8 | protease, serine, 8 | -0.00541645 |
| FOXO1 | forkhead box O1 | -0.00541041 |
| TYR | tyrosinase | -0.00539054 |
| GGCT | gamma-glutamylcyclotransferase | -0.00538249 |
| GEM | GTP binding protein overexpressed in skeletal muscle | -0.00537711 |
| HTR2B | 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled | -0.00537612 |
| GCG | glucagon | -0.00537112 |
| CFB | complement factor B | -0.00532501 |
| TMEM176A | transmembrane protein 176A | -0.00532324 |
| MXRA5 | matrix-remodelling associated 5 | -0.00532174 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | -0.00531965 |
| MAPK1 | mitogen-activated protein kinase 1 | -0.00531735 |
| CHKB | choline kinase beta | -0.00530441 |
| PLTP | phospholipid transfer protein | -0.0053033 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | -0.00529867 |
| CADM1 | cell adhesion molecule 1 | -0.00529318 |
| CCL13 | chemokine (C-C motif) ligand 13 | -0.00528366 |
| BNC2 | basonuclin 2 | -0.00527551 |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 | -0.00526868 |
| FAM198B | family with sequence similarity 198, member B | -0.00525239 |
| UBA1 | ubiquitin-like modifier activating enzyme 1 | -0.00524047 |
| TMEM106C | transmembrane protein 106C | -0.0052374 |
| SCRIB | scribbled planar cell polarity protein | -0.00520973 |
| MYH11 | myosin, heavy chain 11, smooth muscle | -0.00520081 |
| S100A4 | S100 calcium binding protein A4 | -0.00515022 |
| SERTAD2 | SERTA domain containing 2 | -0.00514418 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.00514398 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0051353 |
| SLCO2B1 | solute carrier organic anion transporter family, member 2B1 | -0.00513517 |
| TNS3 | tensin 3 | -0.00513124 |
| NDUFS6 | NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) | -0.00511937 |
| C3AR1 | complement component 3a receptor 1 | -0.00511906 |
| AOC3 | amine oxidase, copper containing 3 | -0.00511318 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.00511151 |
| YBX3 | Y box binding protein 3 | -0.00510618 |
| GDE1 | glycerophosphodiester phosphodiesterase 1 | -0.00509065 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.00508969 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.00508282 |
| SNX7 | sorting nexin 7 | -0.00507903 |
| IL1R2 | interleukin 1 receptor, type II | -0.00507582 |
| MAPK13 | mitogen-activated protein kinase 13 | -0.00507576 |
