POU2F2 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description POU class 2 homeobox 2|The protein encoded by this gene is a homeobox-containing transcription factor of the POU domain family. The encoded protein binds the octamer sequence 5'-ATTTGCAT-3', a common transcription factor binding site in immunoglobulin gene promoters. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011] (NCBI Entrez Gene Database, 5452)
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Genes

312 genes differentially expressed following the POU2F2 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
SLC5A9 solute carrier family 5 (sodium/sugar cotransporter), member 9 2.88771
PEAR1 platelet endothelial aggregation receptor 1 2.88771
ELSPBP1 epididymal sperm binding protein 1 2.88771
TKTL2 transketolase-like 2 2.88771
PAX3 paired box 3 2.88771
PAX6 paired box 6 2.88771
GFAP glial fibrillary acidic protein 2.88771
OLIG1 oligodendrocyte transcription factor 1 2.88771
ASB12 ankyrin repeat and SOCS box containing 12 2.88771
RASSF10 Ras association (RalGDS/AF-6) domain family (N-terminal) member 10 2.88771
NCF4 neutrophil cytosolic factor 4, 40kDa 2.88771
SOX18 SRY (sex determining region Y)-box 18 2.88771
FGD2 FYVE, RhoGEF and PH domain containing 2 2.88771
STMN4 stathmin-like 4 2.88771
AKAP14 A kinase (PRKA) anchor protein 14 2.88771
SERPINA11 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11 2.88771
PLIN4 perilipin 4 2.88771
TMEM176A transmembrane protein 176A 2.88771
BTLA B and T lymphocyte associated 2.88771
ZNF467 zinc finger protein 467 2.88771
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 2.88771
SPINT3 serine peptidase inhibitor, Kunitz type, 3 2.88771
SIM1 single-minded family bHLH transcription factor 1 2.88771
YIPF7 Yip1 domain family, member 7 2.88771
ANKK1 ankyrin repeat and kinase domain containing 1 2.88771
GMNC geminin coiled-coil domain containing 2.88771
SHE Src homology 2 domain containing E 2.88771
COPZ2 coatomer protein complex, subunit zeta 2 2.88771
C3AR1 complement component 3a receptor 1 2.88771
GBP2 guanylate binding protein 2, interferon-inducible 2.88771
PLG plasminogen 2.88771
SLC28A2 solute carrier family 28 (concentrative nucleoside transporter), member 2 2.88771
GPR35 G protein-coupled receptor 35 2.88771
GMFG glia maturation factor, gamma 2.88771
CA1 carbonic anhydrase I 2.88771
TRIM74 tripartite motif containing 74 2.88771
UNC45B unc-45 homolog B (C. elegans) 2.88771
ANKRD34A ankyrin repeat domain 34A 2.88771
FAM221B family with sequence similarity 221, member B 2.88771
ADGB androglobin 2.88771
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12 2.88771
GNAT3 guanine nucleotide binding protein, alpha transducing 3 2.88771
MPL MPL proto-oncogene, thrombopoietin receptor 2.88771
PROX2 prospero homeobox 2 2.88771
PABPC1L2B poly(A) binding protein, cytoplasmic 1-like 2B 2.88771
FMR1NB fragile X mental retardation 1 neighbor 2.88771
CLEC17A C-type lectin domain family 17, member A 2.88771
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 2.88771
C2ORF72 chromosome 2 open reading frame 72 2.88771
CREB3L3 cAMP responsive element binding protein 3-like 3 2.88771
GLP2R glucagon-like peptide 2 receptor 2.88771
TBX5 T-box 5 2.88771
SLC1A7 solute carrier family 1 (glutamate transporter), member 7 2.88771
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 2.88771
ROPN1 rhophilin associated tail protein 1 2.88771
WDR64 WD repeat domain 64 2.88771
CFC1 cripto, FRL-1, cryptic family 1 2.88771
LY6K lymphocyte antigen 6 complex, locus K 2.88771
GATA6 GATA binding protein 6 2.88771
MROH5 maestro heat-like repeat family member 5 2.88771
RNF183 ring finger protein 183 2.88771
UGT2A1 UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus 2.88771
DLK2 delta-like 2 homolog (Drosophila) 2.88771
TFEC transcription factor EC 2.88771
ADGRG1 adhesion G protein-coupled receptor G1 2.88771
TLR8 toll-like receptor 8 2.88771
OVGP1 oviductal glycoprotein 1, 120kDa 2.88771
PKD2L1 polycystic kidney disease 2-like 1 2.88771
HMGCLL1 3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1 2.88771
SLFN11 schlafen family member 11 2.88771
CD9 CD9 molecule 2.88771
RASL10A RAS-like, family 10, member A 2.88771
LAX1 lymphocyte transmembrane adaptor 1 2.88771
OTOR otoraplin 2.88771
RAET1E retinoic acid early transcript 1E 2.88771
TBX21 T-box 21 2.88771
PLCXD3 phosphatidylinositol-specific phospholipase C, X domain containing 3 2.88771
PTPRC protein tyrosine phosphatase, receptor type, C 2.88771
PTPRQ protein tyrosine phosphatase, receptor type, Q 2.88771
MLN motilin 2.88771
DTHD1 death domain containing 1 2.88771
PCDHA1 protocadherin alpha 1 2.88771
ACTL8 actin-like 8 2.88771
RS1 retinoschisin 1 2.88771
OR2A25 olfactory receptor, family 2, subfamily A, member 25 2.88771
ASB15 ankyrin repeat and SOCS box containing 15 2.88771
ARR3 arrestin 3, retinal (X-arrestin) 2.88771
STPG3 sperm-tail PG-rich repeat containing 3 2.88771
RHEX regulator of hemoglobinization and erythroid cell expansion 2.88771
PAGE4 P antigen family, member 4 (prostate associated) 2.88771
H3C13 H3 clustered histone 13 2.88771
TNIP3 TNFAIP3 interacting protein 3 2.88771
EVPLL envoplakin-like 2.88771
P2RY13 purinergic receptor P2Y, G-protein coupled, 13 2.88771
COX7B2 cytochrome c oxidase subunit VIIb2 2.88771
SPINK9 serine peptidase inhibitor, Kazal type 9 2.88771
CFAP107 cilia and flagella associated protein 107 2.88771
ADAM7 ADAM metallopeptidase domain 7 2.88771
CRYBB3 crystallin, beta B3 2.88771
CYSLTR2 cysteinyl leukotriene receptor 2 2.88771
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 2.88771
TIGD3 tigger transposable element derived 3 2.88771
C2ORF66 chromosome 2 open reading frame 66 2.88771
MAP3K19 mitogen-activated protein kinase kinase kinase 19 2.88771
MKRN3 makorin ring finger protein 3 2.88771
PRM1 protamine 1 2.88771
CATIP ciliogenesis associated TTC17 interacting protein 2.88771
CFAP47 cilia and flagella associated protein 47 2.88771
KCNV1 potassium channel, voltage gated modifier subfamily V, member 1 2.88771
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2 2.88771
LMX1A LIM homeobox transcription factor 1, alpha 2.88771
PLA2G5 phospholipase A2, group V 2.88771
TTC24 tetratricopeptide repeat domain 24 2.88771
DRC1 dynein regulatory complex subunit 1 2.88771
CIMIP2A ciliary microtubule inner protein 2A 2.88771
PHACTR3 phosphatase and actin regulator 3 2.88771
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 2.88771
TBC1D3I TBC1 domain family member 3I 2.88771
WASH8P WAS protein family homolog 8, pseudogene 2.88771
KIF1C-AS1 KIF1C antisense RNA 1 2.88771
AICDA activation-induced cytidine deaminase 2.88771
LSMEM1 leucine-rich single-pass membrane protein 1 2.88771
GSTA1 glutathione S-transferase alpha 1 2.88771
CIMAP1D CIMAP1 family member D 2.88771
SYNGR4 synaptogyrin 4 2.88771
NT5C1B 5'-nucleotidase, cytosolic IB 2.88771
NOTCH2NLB notch 2 N-terminal like B 2.88771
POTEM POTE ankyrin domain family, member M 2.88771
KRT15 keratin 15, type I 2.88771
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 2.88771
GHRH growth hormone releasing hormone 2.88771
IRX4 iroquois homeobox 4 2.88771
CPHXL2 cytoplasmic polyadenylated homeobox like 2 2.88771
GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble) 2.88771
ANGPTL5 angiopoietin-like 5 2.88771
ST18 suppression of tumorigenicity 18, zinc finger 2.88771
CIB3 calcium and integrin binding family member 3 2.88771
SLC51B solute carrier family 51, beta subunit 2.88771
PRDX1 peroxiredoxin 1 2.88771
HIGD1C HIG1 hypoxia inducible domain family, member 1C 2.88771
NRSN1 neurensin 1 2.88771
ELFN2 extracellular leucine-rich repeat and fibronectin type III domain containing 2 2.88771
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal) 2.88771
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 2.88771
PNLDC1 poly(A)-specific ribonuclease (PARN)-like domain containing 1 2.88771
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1 2.88771
SELE selectin E 2.88771
NKD2 naked cuticle homolog 2 (Drosophila) 2.88771
SQOR sulfide quinone oxidoreductase 2.88771
OR52I2 olfactory receptor, family 52, subfamily I, member 2 2.88771
NSG2 neuronal vesicle trafficking associated 2 2.88771
CLDN34 claudin 34 2.88771
CCDC190 coiled-coil domain containing 190 2.88771
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1 2.88771
CFAP141 cilia and flagella associated protein 141 2.88771
ENDOU endonuclease, polyU-specific 2.88771
AKR1B15 aldo-keto reductase family 1, member B15 2.88771
HAMP hepcidin antimicrobial peptide 2.88771
OPRK1 opioid receptor, kappa 1 2.88771
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon 2.88771
RORC RAR-related orphan receptor C 2.88771
TCF21 transcription factor 21 2.88771
ELANE elastase, neutrophil expressed 2.88771
CD80 CD80 molecule 2.88771
GH1 growth hormone 1 2.88771
CCDC187 coiled-coil domain containing 187 2.88771
CALML6 calmodulin-like 6 2.88771
AMER2 APC membrane recruitment protein 2 2.88771
TSHZ3 teashirt zinc finger homeobox 3 2.86951
HACD3 3-hydroxyacyl-CoA dehydratase 3 2.8253
PRSS53 protease, serine, 53 2.75575
NDUFAF8 NADH:ubiquinone oxidoreductase complex assembly factor 8 2.7047
CATSPER4 cation channel, sperm associated 4 2.57212
GGNBP2 gametogenetin binding protein 2 2.5599
INO80E INO80 complex subunit E 2.54974
ZDHHC14 zinc finger, DHHC-type containing 14 2.52615
CCDC126 coiled-coil domain containing 126 2.49366
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 2.44849
ERMN ermin, ERM-like protein 2.43453
C11ORF16 chromosome 11 open reading frame 16 2.43453
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 2.42566
BOD1 biorientation of chromosomes in cell division 1 2.37491
AKAP3 A kinase (PRKA) anchor protein 3 2.35766
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 2.32595
NCBP3 nuclear cap binding subunit 3 2.29388
TDGF1 teratocarcinoma-derived growth factor 1 2.29252
CALU calumenin 2.23832
TOPBP1 topoisomerase (DNA) II binding protein 1 2.22396
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like 2.22274
TMEM31 transmembrane protein 31 2.21935
EWSR1 EWS RNA-binding protein 1 2.20537
SLC68A1 solute carrier family 68 member 1 2.2032
FOXK1 forkhead box K1 2.20268
CLUL1 clusterin-like 1 (retinal) 2.16492
MPI mannose phosphate isomerase 2.16103
WDR1 WD repeat domain 1 2.15513
ATP5IF1 ATP synthase inhibitory factor subunit 1 2.15225
HIPK1 homeodomain interacting protein kinase 1 2.13827
PFDN4 prefoldin subunit 4 2.13205
EMC4 ER membrane protein complex subunit 4 2.12416
AJUBA ajuba LIM protein 2.12134
TLN1 talin 1 2.06238
MMADHC methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria 2.04577
NIPAL3 NIPA-like domain containing 3 2.04294
PNKD paroxysmal nonkinesigenic dyskinesia 2.0374
PTPRS protein tyrosine phosphatase, receptor type, S 2.03724
DBN1 drebrin 1 2.03724
MAPRE1 microtubule-associated protein, RP/EB family, member 1 2.03593
TMEFF2 transmembrane protein with EGF-like and two follistatin-like domains 2 2.02807
ZHX3 zinc fingers and homeoboxes 3 2.02807
TMEM106B transmembrane protein 106B 2.02734
CLMN calmin (calponin-like, transmembrane) 2.01402

decreased expression

Symbol Name Standardized Value
PRRT1 proline-rich transmembrane protein 1 -2.88771
DUSP9 dual specificity phosphatase 9 -2.88771
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) -2.88771
UBN2 ubinuclein 2 -2.88771
NECTIN4 nectin cell adhesion molecule 4 -2.88771
SYCE3 synaptonemal complex central element protein 3 -2.88771
SPDEF SAM pointed domain containing ETS transcription factor -2.88771
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 -2.88771
ACAN aggrecan -2.88771
LOC112694756 uncharaterized LOC112694756 -2.88771
ATP5MGL ATP synthase membrane subunit g like -2.88771
C17ORF107 chromosome 17 open reading frame 107 -2.88771
PAX7 paired box 7 -2.88771
TMEM151A transmembrane protein 151A -2.88771
SPAG4 sperm associated antigen 4 -2.88771
ZNF575 zinc finger protein 575 -2.88771
CENPS centromere protein S -2.88771
LRRC73 leucine rich repeat containing 73 -2.88771
MYEOV myeloma overexpressed -2.88771
THPO thrombopoietin -2.88771
CYP2F1 cytochrome P450, family 2, subfamily F, polypeptide 1 -2.88771
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma -2.88771
FER1L6 fer-1-like family member 6 -2.88771
NPPC natriuretic peptide C -2.88771
PDF peptide deformylase (mitochondrial) -2.88771
ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8 -2.88771
IL4R interleukin 4 receptor -2.88771
ADAM8 ADAM metallopeptidase domain 8 -2.88771
IQCN IQ motif containing N -2.88771
ITGA10 integrin, alpha 10 -2.88771
ZC3H12D zinc finger CCCH-type containing 12D -2.88771
PHF21A PHD finger protein 21A -2.88771
SPHKAP SPHK1 interactor, AKAP domain containing -2.88771
EPB41L4A erythrocyte membrane protein band 4.1 like 4A -2.88771
CATSPERZ catsper channel auxiliary subunit zeta -2.88771
CTSF cathepsin F -2.88771
LOC124906010 uncharacterized LOC124906010 -2.88771
RNFT1 ring finger protein, transmembrane 1 -2.88771
ERVV-2 endogenous retrovirus group V, member 2 -2.88771
DQX1 DEAQ box RNA-dependent ATPase 1 -2.88771
SNAP91 synaptosomal-associated protein, 91kDa -2.86196
NPY neuropeptide Y -2.86196
SIGLEC10 sialic acid binding Ig-like lectin 10 -2.80354
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) -2.74327
GPC4 glypican 4 -2.74327
E2F6 E2F transcription factor 6 -2.7319
AIF1 allograft inflammatory factor 1 -2.7047
NRG1 neuregulin 1 -2.68317
CNTN2 contactin 2 (axonal) -2.58534
DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B -2.57181
CDK18 cyclin-dependent kinase 18 -2.57181
SMOC1 SPARC related modular calcium binding 1 -2.52419
ZNF600 zinc finger protein 600 -2.47342
WIF1 WNT inhibitory factor 1 -2.47342
FAM53B family with sequence similarity 53, member B -2.44849
CDK5 cyclin-dependent kinase 5 -2.34282
BNC2 basonuclin 2 -2.32435
ITM2C integral membrane protein 2C -2.29305
ASPH aspartate beta-hydroxylase -2.29305
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha -2.29169
C1QTNF12 C1q and TNF related 12 -2.23832
NDNF neuron-derived neurotrophic factor -2.23832
USP16 ubiquitin specific peptidase 16 -2.22274
ZNF658 zinc finger protein 658 -2.21464
ANKFN1 ankyrin-repeat and fibronectin type III domain containing 1 -2.21464
NBPF14 neuroblastoma breakpoint family, member 14 -2.21464
TMEM187 transmembrane protein 187 -2.2032
ANKRD31 ankyrin repeat domain 31 -2.19595
LRRC4 leucine rich repeat containing 4 -2.18746
RO60 Ro60, Y RNA binding protein -2.14216
PIERCE1 piercer of microtubule wall 1 -2.11444
AGTPBP1 ATP/GTP binding protein 1 -2.11444
C2ORF92 chromosome 2 open reading frame 92 -2.11444
DNAL1 dynein, axonemal, light chain 1 -2.08677
TMEM131L transmembrane 131 like -2.0831
METTL22 methyltransferase like 22 -2.06993
MIGA2 mitoguardin 2 -2.06993
SGSM2 small G protein signaling modulator 2 -2.0494
SPIN1 spindlin 1 -2.04294
BORCS6 BLOC-1 related complex subunit 6 -2.04294
CLIP1 CAP-GLY domain containing linker protein 1 -2.04294
GDF15 growth differentiation factor 15 -2.03779
OMA1 OMA1 zinc metallopeptidase -2.0374
DCAF16 DDB1 and CUL4 associated factor 16 -2.0374
EVC Ellis van Creveld protein -2.03724
GJD3 gap junction protein, delta 3, 31.9kDa -2.03724
LINC02560 long intergenic non-protein coding RNA 2560 -2.03724
MAP3K14 mitogen-activated protein kinase kinase kinase 14 -2.03724
AXDND1 axonemal dynein light chain domain containing 1 -2.03724
NXPH2 neurexophilin 2 -2.03724
FAM219A family with sequence similarity 219, member A -2.02889
BIK BCL2-interacting killer (apoptosis-inducing) -2.02807
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9 -2.02807
CELA2B chymotrypsin-like elastase family, member 2B -2.02807
RILPL1 Rab interacting lysosomal protein-like 1 -2.02734
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3) -2.01402
FOXO3B forkhead box O3B pseudogene -2.01402
IGSF6 immunoglobulin superfamily, member 6 -2.00109
KLHL9 kelch-like family member 9 -2.00109
SOX5 SRY (sex determining region Y)-box 5 -2.00109