POU2F3 Gene Set

Dataset MotifMap Predicted Transcription Factor Targets
Category genomics
Type transcription factor
Description POU class 2 homeobox 3|This gene encodes a member of the POU domain family of transcription factors. POU domain transcription factors bind to a specific octamer DNA motif and regulate cell type-specific differentiation pathways. The encoded protein is primarily expressed in the epidermis, and plays a critical role in keratinocyte proliferation and differentiation. The encoded protein is also a candidate tumor suppressor protein, and aberrant promoter methylation of this gene may play a role in cervical cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011] (NCBI Entrez Gene Database, 25833)
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Genes

20 target genes of the POU2F3 transcription factor predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset.

Symbol Name
ADGRL2 adhesion G protein-coupled receptor L2
ANKRD13A ankyrin repeat domain 13A
BNC2 basonuclin 2
CDC25B cell division cycle 25B
CSRNP3 cysteine-serine-rich nuclear protein 3
GADD45A growth arrest and DNA-damage-inducible, alpha
GRAP2 GRB2-related adaptor protein 2
HIST1H2AC histone cluster 1, H2ac
HIST1H2BM histone cluster 1, H2bm
HIST2H2AC histone cluster 2, H2ac
HIST2H2BF histone cluster 2, H2bf
KIAA1217 KIAA1217
LOC643355 uncharacterized LOC643355
MIR548I4 microRNA 548i-4
NFE2L1 nuclear factor, erythroid 2-like 1
POU2F1 POU class 2 homeobox 1
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SPRED1 sprouty-related, EVH1 domain containing 1
TMEM39B transmembrane protein 39B
ZHX2 zinc fingers and homeoboxes 2