POU4F1 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description POU class 4 homeobox 1|This gene encodes a member of the POU-IV class of neural transcription factors. This protein is expressed in a subset of retinal ganglion cells and may be involved in the developing sensory nervous system. This protein may also promote the growth of cervical tumors. A translocation of this gene is associated with some adult acute myeloid leukemias. [provided by RefSeq, Mar 2012] (NCBI Entrez Gene Database, 5457)
Similar Terms
Downloads & Tools

Genes

302 genes differentially expressed following the POU4F1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
LANCL3 LanC lantibiotic synthetase component C-like 3 (bacterial) 4.39171
BTLA B and T lymphocyte associated 4.39171
CD70 CD70 molecule 4.39171
SLC26A7 solute carrier family 26 (anion exchanger), member 7 4.39171
MPL MPL proto-oncogene, thrombopoietin receptor 4.39171
RAG2 recombination activating gene 2 4.39171
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 4.39171
CD5 CD5 molecule 4.39171
GNG8 guanine nucleotide binding protein (G protein), gamma 8 4.39171
SLC22A8 solute carrier family 22 (organic anion transporter), member 8 4.39171
SDSL serine dehydratase-like 4.39171
HEATR9 HEAT repeat containing 9 4.39171
HCRTR2 hypocretin (orexin) receptor 2 4.39171
PDCD1 programmed cell death 1 4.39171
CAPSL calcyphosine-like 4.39171
MYH11 myosin, heavy chain 11, smooth muscle 4.39171
CLDN34 claudin 34 4.39171
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 4.39171
SCN10A sodium channel, voltage gated, type X alpha subunit 4.39171
FAM221B family with sequence similarity 221, member B 4.39171
TSPAN19 tetraspanin 19 4.39171
SMIM43 small integral membrane protein 43 4.39171
TTR transthyretin 4.38693
IGFL4 IGF-like family member 4 4.38693
SSTR5 somatostatin receptor 5 4.38693
C2ORF80 chromosome 2 open reading frame 80 4.38693
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 4.38693
TNIP3 TNFAIP3 interacting protein 3 4.38693
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa 4.38693
TTLL2 tubulin tyrosine ligase-like family member 2 4.38693
BMP5 bone morphogenetic protein 5 4.38693
BTBD16 BTB (POZ) domain containing 16 4.38693
CCDC87 coiled-coil domain containing 87 4.38693
DDX53 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 4.38693
STEAP4 STEAP family member 4 4.38693
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4 4.38693
RNF39 ring finger protein 39 4.38693
MLANA melan-A 4.38693
PODNL1 podocan-like 1 4.38693
ATP1A4 ATPase, Na+/K+ transporting, alpha 4 polypeptide 4.38693
TAS2R13 taste receptor, type 2, member 13 4.38693
HTR3E 5-hydroxytryptamine (serotonin) receptor 3E, ionotropic 4.38693
OXT oxytocin/neurophysin I prepropeptide 4.38693
SPINK13 serine peptidase inhibitor, Kazal type 13 (putative) 4.38693
TCP11 t-complex 11, testis-specific 4.38693
TPH1 tryptophan hydroxylase 1 4.38693
WDR93 WD repeat domain 93 4.38693
NPIPB8 nuclear pore complex interacting protein family, member B8 4.38693
MS4A13 membrane-spanning 4-domains, subfamily A, member 13 4.38693
COL19A1 collagen, type XIX, alpha 1 4.38693
FRMD7 FERM domain containing 7 4.38693
CCR3 chemokine (C-C motif) receptor 3 4.38693
PIWIL1 piwi-like RNA-mediated gene silencing 1 4.38693
SLC35D3 solute carrier family 35, member D3 4.38693
GGT5 gamma-glutamyltransferase 5 4.38693
TMIE transmembrane inner ear 4.38693
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 4.38693
CKM creatine kinase, muscle 4.38693
OR51B5 olfactory receptor, family 51, subfamily B, member 5 4.38693
UROC1 urocanate hydratase 1 4.38693
TMEM235 transmembrane protein 235 4.38693
MSX1 msh homeobox 1 4.38693
LRIT3 leucine-rich repeat, immunoglobulin-like and transmembrane domains 3 4.38693
C1ORF162 chromosome 1 open reading frame 162 4.38693
UTS2 urotensin 2 4.38693
MYBPHL myosin binding protein H-like 4.38693
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 4.38693
CSTL1 cystatin-like 1 4.38693
ZAR1L zygote arrest 1-like 4.38693
OR10A2 olfactory receptor, family 10, subfamily A, member 2 4.38693
RASSF10 Ras association (RalGDS/AF-6) domain family (N-terminal) member 10 4.38693
TBX18 T-box 18 4.38693
ZNF467 zinc finger protein 467 4.38693
CELA3B chymotrypsin-like elastase family, member 3B 4.38693
DCAF4L2 DDB1 and CUL4 associated factor 4-like 2 4.38693
SHC4 SHC (Src homology 2 domain containing) family, member 4 4.38693
FGFBP2 fibroblast growth factor binding protein 2 4.38693
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila) 4.38693
SLC26A9 solute carrier family 26 (anion exchanger), member 9 4.38693
ZNF503 zinc finger protein 503 4.38693
ASB15 ankyrin repeat and SOCS box containing 15 4.38693
NYAP2 neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2 4.38693
KCNJ9 potassium channel, inwardly rectifying subfamily J, member 9 4.38693
C1QTNF9B C1q and tumor necrosis factor related protein 9B 4.38693
LRRC43 leucine rich repeat containing 43 4.38693
SLC17A8 solute carrier family 17 (vesicular glutamate transporter), member 8 4.38693
SLC37A2 solute carrier family 37 (glucose-6-phosphate transporter), member 2 4.38693
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 4.38693
SPATA9 spermatogenesis associated 9 4.38693
FSHR follicle stimulating hormone receptor 4.38693
H2BW1 H2B.W histone 1 4.38693
PABPN1L poly(A) binding protein, nuclear 1-like (cytoplasmic) 4.38693
CFAP206 cilia and flagella associated protein 206 4.38693
KLK4 kallikrein-related peptidase 4 4.38693
ODF4 outer dense fiber of sperm tails 4 4.38693
EMP1 epithelial membrane protein 1 4.38693
GABRR1 gamma-aminobutyric acid (GABA) A receptor, rho 1 4.38693
SPINK9 serine peptidase inhibitor, Kazal type 9 4.38693
GOLGA6B golgin A6 family, member B 4.38693
SPATA46 spermatogenesis associated 46 4.38693
AJM1 apical junction component 1 homolog 4.38693
DMRT2 doublesex and mab-3 related transcription factor 2 4.38693
OTOP1 otopetrin 1 4.38693
TEKTL1 tektin like 1 4.38693
RIIAD1 regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1 4.38693
GOLGA8K golgin A8 family, member K 4.38693
BTG4 B-cell translocation gene 4 4.38693
TTC22 tetratricopeptide repeat domain 22 4.38693
NPY2R neuropeptide Y receptor Y2 4.38693
C1ORF185 chromosome 1 open reading frame 185 4.38693
PLA2G5 phospholipase A2, group V 4.38693
EXOC1L exocyst complex component 1 like 4.38693
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 4.38693
GCGR glucagon receptor 4.38693
CFAP276 cilia and flagella associated protein 276 4.38693
IDI2 isopentenyl-diphosphate delta isomerase 2 4.38693
PGR progesterone receptor 4.38693
CTSW cathepsin W 4.38693
GPR61 G protein-coupled receptor 61 4.38693
ANKRD63 ankyrin repeat domain 63 4.38693
CD22 CD22 molecule 4.38693
POU3F2 POU class 3 homeobox 2 4.38693
ZG16 zymogen granule protein 16 4.38693
GCM2 glial cells missing homolog 2 (Drosophila) 4.38693
ZBED6 zinc finger, BED-type containing 6 4.38693
DUOXA1 dual oxidase maturation factor 1 4.38693
LY6G5C lymphocyte antigen 6 complex, locus G5C 4.38693
TGM4 transglutaminase 4 4.38693
TGM6 transglutaminase 6 4.38693
PPP1R3G protein phosphatase 1, regulatory subunit 3G 4.38693
SPDYE2B speedy/RINGO cell cycle regulator family member E2B 4.38693
KCNK16 potassium channel, two pore domain subfamily K, member 16 4.38693
GPRC5A G protein-coupled receptor, class C, group 5, member A 4.38693
LPO lactoperoxidase 4.38693
PKD2L1 polycystic kidney disease 2-like 1 4.38693
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 4.38693
NUTM2A NUT family member 2A 4.38693
C9ORF57 chromosome 9 open reading frame 57 4.38693
AQP7 aquaporin 7 4.38693
AQP9 aquaporin 9 4.38693
GRK1 G protein-coupled receptor kinase 1 4.38693
LCT lactase 4.38693
CH25H cholesterol 25-hydroxylase 4.38693
OXER1 oxoeicosanoid (OXE) receptor 1 4.38693
IRAG2 inositol 1,4,5-triphosphate receptor associated 2 4.38693
GAL3ST2 galactose-3-O-sulfotransferase 2 4.38693
GP1BB glycoprotein Ib (platelet), beta polypeptide 4.38693
FZD1 frizzled class receptor 1 4.38693
KY kyphoscoliosis peptidase 4.38693
ALX3 ALX homeobox 3 4.38693
SPTBN5 spectrin, beta, non-erythrocytic 5 4.38693
C9ORF50 chromosome 9 open reading frame 50 4.38693
SPATA45 spermatogenesis associated 45 4.31728
FBXO4 F-box protein 4 4.31728
FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial 4.15537
KDM4B lysine (K)-specific demethylase 4B 3.44746
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 3.4384
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 3.41144
CHCT1 CHD1 helical C-terminal domain containing 1 3.41144
IFI16 interferon, gamma-inducible protein 16 3.41144
CD247 CD247 molecule 3.40266
LTAP1 lipid transport auxiliary protein 1 3.36606
CD101 CD101 molecule 3.36606
ARFRP1 ADP-ribosylation factor related protein 1 3.13385
RGS8 regulator of G-protein signaling 8 3.0769
CHMP2B charged multivesicular body protein 2B 3.0137
LAMA4 laminin, alpha 4 2.97498
FASTKD2 FAST kinase domains 2 2.71247
RPF2 ribosome production factor 2 homolog (S. cerevisiae) 2.71247
FAM229B family with sequence similarity 229, member B 2.68779
LPCAT3 lysophosphatidylcholine acyltransferase 3 2.60341
ABHD14B abhydrolase domain containing 14B 2.51742
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3 2.45041
KRTAP13-4 keratin associated protein 13-4 2.43347
GJA9 gap junction protein, alpha 9, 59kDa 2.43347
PRRT4 proline-rich transmembrane protein 4 2.43347
EAPP E2F-associated phosphoprotein 2.41742
RAD23B RAD23 homolog B (S. cerevisiae) 2.38533
JAKMIP2 janus kinase and microtubule interacting protein 2 2.37966
MAP7 microtubule-associated protein 7 2.37872
TRIM11 tripartite motif containing 11 2.36717
ARHGEF25 Rho guanine nucleotide exchange factor (GEF) 25 2.35926
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide 2.34868
GDAP2 ganglioside induced differentiation associated protein 2 2.34868
ACBD4 acyl-CoA binding domain containing 4 2.30828
FAM199X family with sequence similarity 199, X-linked 2.29621
DPF1 D4, zinc and double PHD fingers family 1 2.29621
MED11 mediator complex subunit 11 2.29621
NGLY1 N-glycanase 1 2.25928
LRRC61 leucine rich repeat containing 61 2.25928
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 2.24907
TSEN2 TSEN2 tRNA splicing endonuclease subunit 2.23953
MRPS21 mitochondrial ribosomal protein S21 2.23448
PUS1 pseudouridylate synthase 1 2.16391
PTCD2 pentatricopeptide repeat domain 2 2.1582
TIAM1 T-cell lymphoma invasion and metastasis 1 2.13161
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 2.07313
ASF1B anti-silencing function 1B histone chaperone 2.02951
ASB13 ankyrin repeat and SOCS box containing 13 2.02056
DUOX1 dual oxidase 1 2.0199
SLK STE20-like kinase 2.01765
TRAF4 TNF receptor-associated factor 4 2.01701
SOD3 superoxide dismutase 3, extracellular 2.00719

decreased expression

Symbol Name Standardized Value
CTRL chymotrypsin-like -4.39171
SPATA17 spermatogenesis associated 17 -4.39171
DUSP15 dual specificity phosphatase 15 -4.38693
PLIN5 perilipin 5 -4.38693
PRAM1 PML-RARA regulated adaptor molecule 1 -4.38693
INHBC inhibin, beta C -4.22102
KCNK2 potassium channel, two pore domain subfamily K, member 2 -4.22102
C5AR2 complement component 5a receptor 2 -4.22102
BTN1A1 butyrophilin, subfamily 1, member A1 -4.22102
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 -4.22102
PGAM2 phosphoglycerate mutase 2 (muscle) -4.22102
CCDC63 coiled-coil domain containing 63 -4.22102
FOXP3 forkhead box P3 -4.22102
DUSP10 dual specificity phosphatase 10 -4.22102
FETUB fetuin B -4.22102
POPDC2 popeye domain containing 2 -4.22102
SHISA7 shisa family member 7 -4.22102
GRM6 glutamate receptor, metabotropic 6 -4.22102
SHOX2 short stature homeobox 2 -4.22102
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 -4.22102
IGIP IgA-inducing protein -4.22102
CFAP52 cilia and flagella associated protein 52 -4.22102
SOSTDC1 sclerostin domain containing 1 -4.22102
RSPH14 radial spoke head 14 homolog (Chlamydomonas) -4.22102
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) -4.22102
ABCB5 ATP-binding cassette, sub-family B (MDR/TAP), member 5 -4.22102
SCARF1 scavenger receptor class F, member 1 -4.22102
SAPCD1 suppressor APC domain containing 1 -4.22102
FAM43B family with sequence similarity 43, member B -4.22102
INHA inhibin, alpha -4.22102
LOC124904542 uncharacterized LOC124904542 -4.22102
HTRA4 HtrA serine peptidase 4 -4.22102
HRH3 histamine receptor H3 -4.22102
TTLL10 tubulin tyrosine ligase-like family member 10 -4.22102
GPR149 G protein-coupled receptor 149 -4.22102
ARL9 ADP-ribosylation factor-like 9 -4.0774
CEACAM19 carcinoembryonic antigen-related cell adhesion molecule 19 -4.0774
EIF2B4 eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa -3.73607
VAMP4 vesicle-associated membrane protein 4 -3.64306
VPS9D1 VPS9 domain containing 1 -3.48706
BCLAF3 BCLAF1 and THRAP3 family member 3 -3.23723
DYNLT2B dynein light chain Tctex-type 2B -2.93559
TSBP1 testis expressed basic protein 1 -2.92725
TRIM17 tripartite motif containing 17 -2.92725
ARC activity-regulated cytoskeleton-associated protein -2.92725
PCDH17 protocadherin 17 -2.92725
CUBN cubilin (intrinsic factor-cobalamin receptor) -2.92725
H4C11 H4 clustered histone 11 -2.92725
PTPN12 protein tyrosine phosphatase, non-receptor type 12 -2.92725
CNBD2 cyclic nucleotide binding domain containing 2 -2.92725
NUDT17 nudix (nucleoside diphosphate linked moiety X)-type motif 17 -2.92725
WFDC2 WAP four-disulfide core domain 2 -2.90565
POGLUT3 protein O-glucosyltransferase 3 -2.88539
SIRT2 sirtuin 2 -2.74773
ZNF550 zinc finger protein 550 -2.68637
TBC1D17 TBC1 domain family, member 17 -2.65923
SHISAL2B shisa like 2B -2.56381
FOXO4 forkhead box O4 -2.53227
H1-5 H1.5 linker histone, cluster member -2.33256
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) -2.30267
ZNF256 zinc finger protein 256 -2.29924
MARF1 meiosis regulator and mRNA stability factor 1 -2.29621
LMO7 LIM domain 7 -2.28856
TMEM175 transmembrane protein 175 -2.26194
KIF23 kinesin family member 23 -2.25042
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 -2.23953
MYO18B myosin XVIIIB -2.23953
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived) -2.23466
NICN1 nicolin 1 -2.23448
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 -2.23448
ZFYVE19 zinc finger, FYVE domain containing 19 -2.23004
ZNF284 zinc finger protein 284 -2.21627
IL23A interleukin 23, alpha subunit p19 -2.21627
ZBTB47 zinc finger and BTB domain containing 47 -2.21627
PPP1R9B protein phosphatase 1, regulatory subunit 9B -2.21627
TMEM33 transmembrane protein 33 -2.20101
PPP1R12A protein phosphatase 1, regulatory subunit 12A -2.1582
IPO8 importin 8 -2.13161
HSH2D hematopoietic SH2 domain containing -2.12653
NCMAP noncompact myelin associated protein -2.12653
TMPRSS9 transmembrane protease, serine 9 -2.12653
LPAR4 lysophosphatidic acid receptor 4 -2.11577
GORAB golgin, RAB6-interacting -2.11154
EYA1 EYA transcriptional coactivator and phosphatase 1 -2.10555
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3 -2.10177
UQCRC1 ubiquinol-cytochrome c reductase core protein I -2.09386
ZER1 zyg-11 related, cell cycle regulator -2.09277
TUBA1A tubulin, alpha 1a -2.07313
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 -2.07232
TTF2 transcription termination factor, RNA polymerase II -2.06354
PSME3IP1 proteasome activator subunit 3 interacting protein 1 -2.05681
CPS1 carbamoyl-phosphate synthase 1, mitochondrial -2.04727
FABP7 fatty acid binding protein 7, brain -2.04556
ARMCX5 armadillo repeat containing, X-linked 5 -2.04157
GTPBP3 GTP binding protein 3 (mitochondrial) -2.03346
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) -2.02056
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11 -2.01455
ZNF354B zinc finger protein 354B -2.01455
GOLGA2 golgin A2 -2.0013