POU4F2 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description POU class 4 homeobox 2|The protein encoded by this gene is a member of the POU-domain transcription factor family and may be involved in maintaining visual system neurons in the retina. The level of the encoded protein is also elevated in a majority of breast cancers, resulting in accelerated tumor growth. [provided by RefSeq, Sep 2011] (NCBI Entrez Gene Database, 5458)
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Genes

293 genes differentially expressed following the POU4F2 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
CEMP1 cementum protein 1 2.62541
CELA3A chymotrypsin-like elastase family, member 3A 2.62541
WNT3A wingless-type MMTV integration site family, member 3A 2.62541
GLYAT glycine-N-acyltransferase 2.62541
CCNB3 cyclin B3 2.62541
OR10A2 olfactory receptor, family 10, subfamily A, member 2 2.62541
OR2AG2 olfactory receptor, family 2, subfamily AG, member 2 2.62541
CCL5 chemokine (C-C motif) ligand 5 2.62541
MUC5B mucin 5B, oligomeric mucus/gel-forming 2.62541
TRIM15 tripartite motif containing 15 2.62541
TMEM176A transmembrane protein 176A 2.62541
TMEM176B transmembrane protein 176B 2.62541
ARID3C AT rich interactive domain 3C (BRIGHT-like) 2.62541
MAP3K7CL MAP3K7 C-terminal like 2.62541
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1 2.62541
VTN vitronectin 2.62541
AKR7L aldo-keto reductase family 7-like (gene/pseudogene) 2.62541
SIGLECL1 SIGLEC family like 1 2.62541
ASPDH aspartate dehydrogenase domain containing 2.62541
NANOS3 nanos homolog 3 (Drosophila) 2.62541
MBD3L5 methyl-CpG binding domain protein 3-like 5 2.62541
FETUB fetuin B 2.62541
TUBB8 tubulin, beta 8 class VIII 2.62541
KLHL24 kelch-like family member 24 2.62541
OC90 otoconin 90 2.62541
TMEM121 transmembrane protein 121 2.62541
GNRHR gonadotropin-releasing hormone receptor 2.62541
B3GNT6 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 2.62541
CORO6 coronin 6 2.62541
AIRE autoimmune regulator 2.62541
FGF9 fibroblast growth factor 9 2.62541
OCSTAMP osteoclast stimulatory transmembrane protein 2.62541
CRIP1 cysteine-rich protein 1 (intestinal) 2.62541
RLN3 relaxin 3 2.62541
SLC30A4 solute carrier family 30 (zinc transporter), member 4 2.62541
RPE65 retinal pigment epithelium-specific protein 65kDa 2.62541
MFAP4 microfibrillar-associated protein 4 2.62541
PBOV1 prostate and breast cancer overexpressed 1 2.62541
GPR22 G protein-coupled receptor 22 2.62541
TNIP3 TNFAIP3 interacting protein 3 2.62541
LRRC10B leucine rich repeat containing 10B 2.62541
SLC28A2 solute carrier family 28 (concentrative nucleoside transporter), member 2 2.62541
RNASE7 ribonuclease, RNase A family, 7 2.62541
FOXQ1 forkhead box Q1 2.62541
COXFA4L3 cytochrome c oxidase associated subunit FA4L3 2.62541
SQOR sulfide quinone oxidoreductase 2.62541
ALDOB aldolase B, fructose-bisphosphate 2.62541
GBP4 guanylate binding protein 4 2.62541
GPX2 glutathione peroxidase 2 2.62541
CD300LF CD300 molecule-like family member f 2.62541
PLCZ1 phospholipase C, zeta 1 2.62541
BDKRB1 bradykinin receptor B1 2.62541
SPATA22 spermatogenesis associated 22 2.62541
MYOCOS myocilin opposite strand 2.62541
CCN5 cellular communication network factor 5 2.62541
PRKN parkin RBR E3 ubiquitin protein ligase 2.62541
COXFA4L2 cytochrome c oxidase hypoxia associated subunit FA4L2 2.62541
CSNK2A2IP casein kinase 2 subunit alpha' interacting protein 2.62541
DRC5 dynein regulatory complex subunit 5 2.62541
AGA-DT AGA divergent transcript 2.62541
LINC02798 long intergenic non-protein coding RNA 2798 2.62541
CFAP97D2 CFAP97 domain containing 2 2.62541
SPAAR small regulatory polypeptide of amino acid response 2.62541
CFAP157 cilia and flagella associated protein 157 2.62541
IMPG1 interphotoreceptor matrix proteoglycan 1 2.62541
MAGIX MAGI family member, X-linked 2.62541
ABCA9 ATP-binding cassette, sub-family A (ABC1), member 9 2.62541
C10ORF67 chromosome 10 open reading frame 67 2.62541
IDO2 indoleamine 2,3-dioxygenase 2 2.62541
CLIP4 CAP-GLY domain containing linker protein family, member 4 2.62541
IRF5 interferon regulatory factor 5 2.62541
LTBP2 latent transforming growth factor beta binding protein 2 2.62541
DMP1 dentin matrix acidic phosphoprotein 1 2.62541
RS1 retinoschisin 1 2.62541
PVRIG poliovirus receptor related immunoglobulin domain containing 2.62541
TMEM235 transmembrane protein 235 2.62541
NPIPB9 nuclear pore complex interacting protein family, member B9 2.62541
LRIT3 leucine-rich repeat, immunoglobulin-like and transmembrane domains 3 2.62541
SAMD15 sterile alpha motif domain containing 15 2.62541
IL1R1 interleukin 1 receptor, type I 2.62541
DENND3 DENN/MADD domain containing 3 2.62541
GLIPR1L2 GLI pathogenesis-related 1 like 2 2.62541
MS4A13 membrane-spanning 4-domains, subfamily A, member 13 2.62541
PIWIL1 piwi-like RNA-mediated gene silencing 1 2.62541
LSP1 lymphocyte-specific protein 1 2.62541
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 2.62541
CPNE5 copine V 2.62541
NIM1K NIM1 serine/threonine protein kinase 2.62541
ANKRD66 ankyrin repeat domain 66 2.62541
IL21R interleukin 21 receptor 2.62541
TMEM204 transmembrane protein 204 2.62541
CREG2 cellular repressor of E1A-stimulated genes 2 2.62541
ALDH3B2 aldehyde dehydrogenase 3 family, member B2 2.62541
TTC9B tetratricopeptide repeat domain 9B 2.62541
BAHCC1 BAH domain and coiled-coil containing 1 2.62541
LMOD2 leiomodin 2 (cardiac) 2.62541
CXCR6 chemokine (C-X-C motif) receptor 6 2.62541
CRYBB2 crystallin, beta B2 2.62541
AQP7 aquaporin 7 2.62541
CNTF ciliary neurotrophic factor 2.62541
ZNF703 zinc finger protein 703 2.62541
OXGR1 oxoglutarate (alpha-ketoglutarate) receptor 1 2.62541
CSTA cystatin A (stefin A) 2.62541
SYNE3 spectrin repeat containing, nuclear envelope family member 3 2.62541
MAMDC4 MAM domain containing 4 2.62541
TMEM31 transmembrane protein 31 2.62541
BTNL3 butyrophilin-like 3 2.62541
MUC19 mucin 19, oligomeric 2.62541
CCL15 chemokine (C-C motif) ligand 15 2.62541
ANKRD55 ankyrin repeat domain 55 2.62541
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein 2.62541
LRRC25 leucine rich repeat containing 25 2.62541
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5 2.62541
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1 2.62541
LY6G6C lymphocyte antigen 6 complex, locus G6C 2.62541
OIP5 Opa interacting protein 5 2.62541
CFP complement factor properdin 2.62541
AMH anti-Mullerian hormone 2.62541
CD200R1 CD200 receptor 1 2.62541
ZC3H12D zinc finger CCCH-type containing 12D 2.62541
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 2.62541
ZCCHC12 zinc finger, CCHC domain containing 12 2.62541
KLK14 kallikrein-related peptidase 14 2.62541
FBXO40 F-box protein 40 2.62541
GTF2A1L general transcription factor IIA, 1-like 2.62541
CALR3 calreticulin 3 2.62541
LY96 lymphocyte antigen 96 2.62541
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 2.62541
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 2.62541
ZNF132 zinc finger protein 132 2.62541
KCNK9 potassium channel, two pore domain subfamily K, member 9 2.62541
LAMP3 lysosomal-associated membrane protein 3 2.62541
ACKR2 atypical chemokine receptor 2 2.62541
C5AR2 complement component 5a receptor 2 2.62541
CARD6 caspase recruitment domain family, member 6 2.62541
CHRM4 cholinergic receptor, muscarinic 4 2.62541
NUTM2F NUT family member 2F 2.62541
DCAF8L2 DDB1 and CUL4 associated factor 8-like 2 2.62541
POTEF POTE ankyrin domain family, member F 2.62541
PLA2G1B phospholipase A2, group IB (pancreas) 2.62541
IFITM10 interferon induced transmembrane protein 10 2.62541
BPIFC BPI fold containing family C 2.62541
TMEM156 transmembrane protein 156 2.62541
GRAPL GRB2-related adaptor protein-like 2.62541
ALOX15B arachidonate 15-lipoxygenase, type B 2.62541
NLRP9 NLR family, pyrin domain containing 9 2.62541
TBC1D28 TBC1 domain family, member 28 2.62541
DYTN dystrotelin 2.62541
OR9Q1 olfactory receptor, family 9, subfamily Q, member 1 2.62541
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 2.62541
NGB neuroglobin 2.62541
SOST sclerostin 2.62541
CACNG3 calcium channel, voltage-dependent, gamma subunit 3 2.62541
PRSS21 protease, serine, 21 (testisin) 2.62541
GNG8 guanine nucleotide binding protein (G protein), gamma 8 2.62541
PLA2G4E phospholipase A2, group IVE 2.62541
ASCL1 achaete-scute family bHLH transcription factor 1 2.62541
JMJD6 jumonji domain containing 6 2.59874
KIF15 kinesin family member 15 2.55026
RANBP3 RAN binding protein 3 2.50142
SLCO2A1 solute carrier organic anion transporter family, member 2A1 2.48776
RIPOR2 RHO family interacting cell polarization regulator 2 2.47736
SLF2 SMC5-SMC6 complex localization factor 2 2.45484
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 2.4214
PHLDA2 pleckstrin homology-like domain, family A, member 2 2.40798
BLOC1S6 biogenesis of lysosomal organelles complex-1, subunit 6, pallidin 2.40798
KAT6A K(lysine) acetyltransferase 6A 2.36504
SLC67A2 solute carrier family 67 member 2 2.36504
CETN3 centrin, EF-hand protein, 3 2.35773
SF3B1 splicing factor 3b, subunit 1, 155kDa 2.34286
MROH1 maestro heat-like repeat family member 1 2.34286
EVPL envoplakin 2.33686
TMEM272 transmembrane protein 272 2.31057
TEKT5 tektin 5 2.31009
RUBCN rubicon autophagy regulator 2.30184
SNX17 sorting nexin 17 2.28601
ZNF610 zinc finger protein 610 2.21874
ZNF749 zinc finger protein 749 2.20775
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2 2.19194
PGPEP1 pyroglutamyl-peptidase I 2.18482
SLC12A8 solute carrier family 12, member 8 2.16943
LRRN2 leucine rich repeat neuronal 2 2.16787
AAMDC adipogenesis associated, Mth938 domain containing 2.16787
KIF24 kinesin family member 24 2.13403
SUGCT succinyl-CoA:glutarate-CoA transferase 2.11838
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit 2.11558
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28 2.11412
UBR4 ubiquitin protein ligase E3 component n-recognin 4 2.09636
SH3BGRL SH3 domain binding glutamate-rich protein like 2.08862
ZC3H7B zinc finger CCCH-type containing 7B 2.08625
ZNF586 zinc finger protein 586 2.08625
DOCK10 dedicator of cytokinesis 10 2.07766
CAV2 caveolin 2 2.06289
C2CD3 C2 calcium-dependent domain containing 3 2.05101
NOP58 NOP58 ribonucleoprotein 2.03479
FZD6 frizzled class receptor 6 2.03479
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3 2.00605

decreased expression

Symbol Name Standardized Value
CFAP299 cilia and flagella associated protein 299 -2.62541
RPL32 ribosomal protein L32 -2.62541
IFI6 interferon, alpha-inducible protein 6 -2.62541
HIPK1 homeodomain interacting protein kinase 1 -2.62541
HYPK huntingtin interacting protein K -2.62541
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 -2.62541
VENTX VENT homeobox -2.62541
PRDX1 peroxiredoxin 1 -2.62541
SPINT4 serine peptidase inhibitor, Kunitz type 4 -2.62541
ANGPTL7 angiopoietin-like 7 -2.62541
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2 -2.62541
AOC3 amine oxidase, copper containing 3 -2.62541
GBA3 glucosidase, beta, acid 3 (gene/pseudogene) -2.62541
PTGER4 prostaglandin E receptor 4 (subtype EP4) -2.62541
BAAT bile acid CoA:amino acid N-acyltransferase -2.62541
TMEM121B transmembrane protein 121B -2.62541
NECTIN4 nectin cell adhesion molecule 4 -2.62541
JADE3 jade family PHD finger 3 -2.62541
LMNTD2 lamin tail domain containing 2 -2.62541
PXDC1 PX domain containing 1 -2.62541
PHLDB1 pleckstrin homology-like domain, family B, member 1 -2.62541
RPL21 ribosomal protein L21 -2.62541
RPL10 ribosomal protein L10 -2.62541
TMEM229A transmembrane protein 229A -2.62541
ZEB2 zinc finger E-box binding homeobox 2 -2.62541
PAX5 paired box 5 -2.62541
SEC61B Sec61 beta subunit -2.62541
EBF2 early B-cell factor 2 -2.62541
CD248 CD248 molecule, endosialin -2.62541
TMEM131 transmembrane protein 131 -2.62541
CFAP61 cilia and flagella associated protein 61 -2.62541
ARL3 ADP-ribosylation factor-like 3 -2.62541
TXN2 thioredoxin 2 -2.62541
CLEC4C C-type lectin domain family 4, member C -2.62541
TMED6 transmembrane emp24 protein transport domain containing 6 -2.62541
ZNF835 zinc finger protein 835 -2.62541
PLET1 placenta expressed transcript 1 -2.62541
RPL8 ribosomal protein L8 -2.62541
CALHM2 calcium homeostasis modulator 2 -2.62541
LRRC26 leucine rich repeat containing 26 -2.62541
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3 -2.62541
DNAAF4 dynein axonemal assembly factor 4 -2.57673
AASDH aminoadipate-semialdehyde dehydrogenase -2.55705
SPMIP4 sperm microtubule inner protein 4 -2.55522
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1 -2.55522
FER1L5 fer-1-like family member 5 -2.52402
EMILIN3 elastin microfibril interfacer 3 -2.50816
TBC1D24 TBC1 domain family, member 24 -2.46359
DEMA1 DPM1 ER membrane anchor 1 -2.40798
RPL30 ribosomal protein L30 -2.39054
RPS10 ribosomal protein S10 -2.388
C4ORF36 chromosome 4 open reading frame 36 -2.34286
THOC5 THO complex 5 -2.33676
FKBP14 FK506 binding protein 14, 22 kDa -2.31282
ZSCAN1 zinc finger and SCAN domain containing 1 -2.31282
RFC3 replication factor C (activator 1) 3, 38kDa -2.30264
TOPBP1 topoisomerase (DNA) II binding protein 1 -2.28027
PRMT2 protein arginine methyltransferase 2 -2.27808
RPL18A ribosomal protein L18a -2.27174
RPL13 ribosomal protein L13 -2.25538
APOO apolipoprotein O -2.20094
RPS5 ribosomal protein S5 -2.19506
ARMH4 armadillo like helical domain containing 4 -2.19194
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1 -2.19194
GLRX glutaredoxin (thioltransferase) -2.18267
NSG1 neuron specific gene family member 1 -2.18028
CCDC24 coiled-coil domain containing 24 -2.17819
ZNF775 zinc finger protein 775 -2.16943
PRLR prolactin receptor -2.15714
LMBR1L limb development membrane protein 1-like -2.15714
H2AZ1 H2A.Z variant histone 1 -2.15714
BOLA2B bolA family member 2B -2.15714
QARS1 glutaminyl-tRNA synthetase 1 -2.15701
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 -2.13145
RPL3 ribosomal protein L3 -2.1143
ALG6 ALG6, alpha-1,3-glucosyltransferase -2.1143
CA14 carbonic anhydrase XIV -2.11412
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 -2.11412
CPLX2 complexin 2 -2.10799
SPAG16 sperm associated antigen 16 -2.10799
RPLP2 ribosomal protein, large, P2 -2.09398
TTC38 tetratricopeptide repeat domain 38 -2.09398
MED4 mediator complex subunit 4 -2.08698
ODAD4 outer dynein arm docking complex subunit 4 -2.07766
UQCRH ubiquinol-cytochrome c reductase hinge protein -2.07766
SH3KBP1 SH3-domain kinase binding protein 1 -2.07222
PPP1R3D protein phosphatase 1, regulatory subunit 3D -2.06289
ABLIM3 actin binding LIM protein family, member 3 -2.06289
TMSB4X thymosin beta 4, X-linked -2.05428
CBS cystathionine-beta-synthase -2.05135
MED13L mediator complex subunit 13-like -2.04084
RPL26 ribosomal protein L26 -2.03129
RPS4X ribosomal protein S4, X-linked -2.02531
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 -2.02355
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2 -2.01777
CYCS cytochrome c, somatic -2.01277