POU5F1 Gene Set

Dataset ENCODE Transcription Factor Targets
Category genomics
Type transcription factor
Description POU class 5 homeobox 1|This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. [provided by RefSeq, Oct 2013] (NCBI Entrez Gene Database, 5460)
External Link http://www.ncbi.nlm.nih.gov/gene/5460
Similar Terms
Downloads & Tools

Genes

192 target genes of the POU5F1 transcription factor in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.

Symbol Name
AGPAT4-IT1 AGPAT4 intronic transcript 1
AKIRIN1 akirin 1
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
ALOXE3 arachidonate lipoxygenase 3
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
APOBEC3D apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D
ARHGAP42 Rho GTPase activating protein 42
ARID2 AT rich interactive domain 2 (ARID, RFX-like)
ARSJ arylsulfatase family, member J
ATF7IP activating transcription factor 7 interacting protein
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
C15ORF48 chromosome 15 open reading frame 48
C1ORF127 chromosome 1 open reading frame 127
C1ORF210 chromosome 1 open reading frame 210
C1R complement component 1, r subcomponent
C6ORF52 chromosome 6 open reading frame 52
CA2 carbonic anhydrase II
CACHD1 cache domain containing 1
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1
CAPS2 calcyphosine 2
CBY1 chibby homolog 1 (Drosophila)
CCDC63 coiled-coil domain containing 63
CCDC85A coiled-coil domain containing 85A
CD200 CD200 molecule
CDX1 caudal type homeobox 1
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
CNR2 cannabinoid receptor 2 (macrophage)
CRYZL1 crystallin, zeta (quinone reductase)-like 1
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
DAGLB diacylglycerol lipase, beta
DBIL5P2 diazepam binding inhibitor-like 5 pseudogene 2
DHRS3 dehydrogenase/reductase (SDR family) member 3
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DPPA4 developmental pluripotency associated 4
DUSP12 dual specificity phosphatase 12
E2F7 E2F transcription factor 7
EEF1A1 eukaryotic translation elongation factor 1 alpha 1
ELL elongation factor RNA polymerase II
ESRG embryonic stem cell related (non-protein coding)
ESRP1 epithelial splicing regulatory protein 1
ETV5 ets variant 5
FAT1 FAT atypical cadherin 1
FBXO40 F-box protein 40
FCHO1 FCH domain only 1
FGF2 fibroblast growth factor 2 (basic)
FGFR2 fibroblast growth factor receptor 2
FSBP fibrinogen silencer binding protein
GABRA5 gamma-aminobutyric acid (GABA) A receptor, alpha 5
GADD45G growth arrest and DNA-damage-inducible, gamma
GDF3 growth differentiation factor 3
GIMAP5 GTPase, IMAP family member 5
GRID2 glutamate receptor, ionotropic, delta 2
GRM2 glutamate receptor, metabotropic 2
GRWD1 glutamate-rich WD repeat containing 1
H2AFY H2A histone family, member Y
HESX1 HESX homeobox 1
HIST1H1B histone cluster 1, H1b
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HIST1H2AD histone cluster 1, H2ad
HIST1H2AE histone cluster 1, H2ae
HIST1H2AL histone cluster 1, H2al
HIST1H2BC histone cluster 1, H2bc
HIST1H2BE histone cluster 1, H2be
HIST1H2BF histone cluster 1, H2bf
HIST1H2BG histone cluster 1, H2bg
HIST1H3B histone cluster 1, H3b
HIST1H3D histone cluster 1, H3d
HIST1H4J histone cluster 1, H4j
HNF1A-AS1 HNF1A antisense RNA 1
HORMAD2 HORMA domain containing 2
HOXB1 homeobox B1
HPS4 Hermansky-Pudlak syndrome 4
IER5L immediate early response 5-like
IL22RA2 interleukin 22 receptor, alpha 2
INO80C INO80 complex subunit C
ITSN1 intersectin 1 (SH3 domain protein)
KDM2B lysine (K)-specific demethylase 2B
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
LAMP1 lysosomal-associated membrane protein 1
LCORL ligand dependent nuclear receptor corepressor-like
LEFTY1 left-right determination factor 1
LGALS12 lectin, galactoside-binding, soluble, 12
LINC00273 long intergenic non-protein coding RNA 273
LINGO1 leucine rich repeat and Ig domain containing 1
LOC100131496 uncharacterized LOC100131496
LOC100288748 uncharacterized LOC100288748
LOC652276 potassium channel tetramerization domain containing 5 pseudogene
LRRC4C leucine rich repeat containing 4C
LRRTM3 leucine rich repeat transmembrane neuronal 3
LRRTM4 leucine rich repeat transmembrane neuronal 4
MALAT1 metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
MIR130B microRNA 130b
MIR1538 microRNA 1538
MIR21 microRNA 21
MIR301B microRNA 301b
MIR302A microRNA 302a
MIR302B microRNA 302b
MIR302C microRNA 302c
MIR302D microRNA 302d
MIR3190 microRNA 3190
MIR3191 microRNA 3191
MIR3648-1 microRNA 3648-1
MIR367 microRNA 367
MIR3687-1 microRNA 3687-1
MIR4429 microRNA 4429
MIR4521 microRNA 4521
MIR4674 microRNA 4674
MIR4708 microRNA 4708
MIR4792 microRNA 4792
MIR663A microRNA 663a
MIR885 microRNA 885
MIR9-2 microRNA 9-2
MIR92B microRNA 92b
MRPL44 mitochondrial ribosomal protein L44
MRPL48 mitochondrial ribosomal protein L48
MYNN myoneurin
MYO1F myosin IF
NADK NAD kinase
NANOG Nanog homeobox
NCAM2 neural cell adhesion molecule 2
NCOR2 nuclear receptor corepressor 2
NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)
NEUROG1 neurogenin 1
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NFE2L3 nuclear factor, erythroid 2-like 3
NOTCH1 notch 1
NOXRED1 NADP-dependent oxidoreductase domain containing 1
NPAS4 neuronal PAS domain protein 4
NR6A1 nuclear receptor subfamily 6, group A, member 1
NRARP NOTCH-regulated ankyrin repeat protein
OLAH oleoyl-ACP hydrolase
PAK1IP1 PAK1 interacting protein 1
PCSK1 proprotein convertase subtilisin/kexin type 1
PDCL phosducin-like
PDHA2 pyruvate dehydrogenase (lipoamide) alpha 2
PIPOX pipecolic acid oxidase
PLAC8 placenta-specific 8
PLEKHG2 pleckstrin homology domain containing, family G (with RhoGef domain) member 2
PLXNA2 plexin A2
POGZ pogo transposable element with ZNF domain
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
POU6F1 POU class 6 homeobox 1
PPP1R15B protein phosphatase 1, regulatory subunit 15B
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PXDN peroxidasin
QSER1 glutamine and serine rich 1
RBM17 RNA binding motif protein 17
REST RE1-silencing transcription factor
RIF1 replication timing regulatory factor 1
RNF219 ring finger protein 219
RNU4ATAC RNA, U4atac small nuclear (U12-dependent splicing)
RP9P retinitis pigmentosa 9 pseudogene
SCN1A sodium channel, voltage gated, type I alpha subunit
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SET SET nuclear proto-oncogene
SFRP2 secreted frizzled-related protein 2
SGMS2 sphingomyelin synthase 2
SHF Src homology 2 domain containing F
SLC25A18 solute carrier family 25 (glutamate carrier), member 18
SMARCAD1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
SNRPN small nuclear ribonucleoprotein polypeptide N
SNX16 sorting nexin 16
SRRD SRR1 domain containing
SRRM4 serine/arginine repetitive matrix 4
SSBP2 single-stranded DNA binding protein 2
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STOX2 storkhead box 2
TBL1X transducin (beta)-like 1X-linked
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box)
TGIF2 TGFB-induced factor homeobox 2
THEM4 thioesterase superfamily member 4
TJP2 tight junction protein 2
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNKS1BP1 tankyrase 1 binding protein 1, 182kDa
TRIM24 tripartite motif containing 24
TRIM38 tripartite motif containing 38
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UBC ubiquitin C
USP15 ubiquitin specific peptidase 15
USP44 ubiquitin specific peptidase 44
WDR74 WD repeat domain 74
ZBTB4 zinc finger and BTB domain containing 4
ZFP36L1 ZFP36 ring finger protein-like 1
ZNF343 zinc finger protein 343
ZNF428 zinc finger protein 428
ZNF436 zinc finger protein 436
ZNF536 zinc finger protein 536
ZNF589 zinc finger protein 589