POU5F1 Gene Set

Dataset MotifMap Predicted Transcription Factor Targets
Category genomics
Type transcription factor
Description POU class 5 homeobox 1|This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. [provided by RefSeq, Oct 2013] (NCBI Entrez Gene Database, 5460)
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213 target genes of the POU5F1 transcription factor predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset.

Symbol Name
AATF apoptosis antagonizing transcription factor
AATK-AS1 AATK antisense RNA 1
ABCB10 ATP-binding cassette, sub-family B (MDR/TAP), member 10
ABCC12 ATP-binding cassette, sub-family C (CFTR/MRP), member 12
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ACTC1 actin, alpha, cardiac muscle 1
ADAM5 ADAM metallopeptidase domain 5 (pseudogene)
ADAM9 ADAM metallopeptidase domain 9
ADCY2 adenylate cyclase 2 (brain)
ADGRF5 adhesion G protein-coupled receptor F5
ADGRL3 adhesion G protein-coupled receptor L3
ADRA1A adrenoceptor alpha 1A
ALDH8A1 aldehyde dehydrogenase 8 family, member A1
ALOX12B arachidonate 12-lipoxygenase, 12R type
ALYREF Aly/REF export factor
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ANKRD17 ankyrin repeat domain 17
ARL6 ADP-ribosylation factor-like 6
ARRDC3 arrestin domain containing 3
ATP10D ATPase, class V, type 10D
ATP11B ATPase, class VI, type 11B
B3GALT5 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
BCAS1 breast carcinoma amplified sequence 1
BPHL biphenyl hydrolase-like (serine hydrolase)
C10ORF99 chromosome 10 open reading frame 99
C11ORF30 chromosome 11 open reading frame 30
C11ORF80 chromosome 11 open reading frame 80
C16ORF45 chromosome 16 open reading frame 45
C16ORF62 chromosome 16 open reading frame 62
CADM1 cell adhesion molecule 1
CADM2 cell adhesion molecule 2
CALM2 calmodulin 2 (phosphorylase kinase, delta)
CAMK2N2 calcium/calmodulin-dependent protein kinase II inhibitor 2
CANX calnexin
CCDC67 coiled-coil domain containing 67
CCDC73 coiled-coil domain containing 73
CDH10 cadherin 10, type 2 (T2-cadherin)
CDKL3 cyclin-dependent kinase-like 3
CHN2 chimerin 2
CHTOP chromatin target of PRMT1
CIC capicua transcriptional repressor
CLUL1 clusterin-like 1 (retinal)
CMSS1 cms1 ribosomal small subunit homolog (yeast)
CNTN4 contactin 4
COL25A1 collagen, type XXV, alpha 1
COPB2 coatomer protein complex, subunit beta 2 (beta prime)
CSRNP1 cysteine-serine-rich nuclear protein 1
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CUL1 cullin 1
DDB1 damage-specific DNA binding protein 1, 127kDa
DDX50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
DEK DEK proto-oncogene
DIEXF digestive organ expansion factor homolog (zebrafish)
DLAT dihydrolipoamide S-acetyltransferase
DMRTA1 DMRT-like family A1
DNASE2B deoxyribonuclease II beta
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DNTT DNA nucleotidylexotransferase
DPP6 dipeptidyl-peptidase 6
DPY19L1P2 DPY19L1 pseudogene 2
DSG3 desmoglein 3
DUSP2 dual specificity phosphatase 2
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1
EDEM2 ER degradation enhancer, mannosidase alpha-like 2
EIF4E eukaryotic translation initiation factor 4E
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
EIF5 eukaryotic translation initiation factor 5
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
ERC2 ELKS/RAB6-interacting/CAST family member 2
FADS1 fatty acid desaturase 1
FAM92A1 family with sequence similarity 92, member A1
FBXL22 F-box and leucine-rich repeat protein 22
FBXO9 F-box protein 9
FKBP10 FK506 binding protein 10, 65 kDa
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FMN2 formin 2
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GHITM growth hormone inducible transmembrane protein
GIMAP7 GTPase, IMAP family member 7
GK5 glycerol kinase 5 (putative)
GMDS GDP-mannose 4,6-dehydratase
GMPR2 guanosine monophosphate reductase 2
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GOLGB1 golgin B1
GPCPD1 glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
GPR20 G protein-coupled receptor 20
GRIA1 glutamate receptor, ionotropic, AMPA 1
H2AFY H2A histone family, member Y
HERPUD2 HERPUD family member 2
HES6 hes family bHLH transcription factor 6
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HMGA2 high mobility group AT-hook 2
IER3IP1 immediate early response 3 interacting protein 1
IL23R interleukin 23 receptor
IL31 interleukin 31
INHA inhibin, alpha
ITGA6 integrin, alpha 6
KATNAL2 katanin p60 subunit A-like 2
KCNH5 potassium channel, voltage gated eag related subfamily H, member 5
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
KCTD3 potassium channel tetramerization domain containing 3
KDM1B lysine (K)-specific demethylase 1B
KDM5A lysine (K)-specific demethylase 5A
KIAA1407 KIAA1407
KIDINS220 kinase D-interacting substrate, 220kDa
KIF21B kinesin family member 21B
KLF5 Kruppel-like factor 5 (intestinal)
KLHL3 kelch-like family member 3
KRT23 keratin 23, type I
KRT8 keratin 8, type II
KRT84 keratin 84, type II
KRTAP29-1 keratin associated protein 29-1
LBH limb bud and heart development
LINC00461 long intergenic non-protein coding RNA 461
LINC00544 long intergenic non-protein coding RNA 544
LINC00710 long intergenic non-protein coding RNA 710
LINC00890 long intergenic non-protein coding RNA 890
LOC340113 uncharacterized LOC340113
LOC349160 uncharacterized LOC349160
LPIN2 lipin 2
LPP LIM domain containing preferred translocation partner in lipoma
LRRC30 leucine rich repeat containing 30
LRRC37A5P leucine rich repeat containing 37, member A5, pseudogene
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
LYPD1 LY6/PLAUR domain containing 1
MAP4 microtubule-associated protein 4
MIR3125 microRNA 3125
MIR4665 microRNA 4665
MIR5007 microRNA 5007
MIR575 microRNA 575
MLIP muscular LMNA-interacting protein
MTM1 myotubularin 1
MYLK2 myosin light chain kinase 2
MYO3B myosin IIIB
MYSM1 Myb-like, SWIRM and MPN domains 1
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NDNL2 necdin-like 2
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
NOP14 NOP14 nucleolar protein
NPSR1-AS1 NPSR1 antisense RNA 1
NUCB2 nucleobindin 2
NYAP2 neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2
OSTN osteocrin
PARP14 poly (ADP-ribose) polymerase family, member 14
PCDH11X protocadherin 11 X-linked
PCDH11Y protocadherin 11 Y-linked
PCIF1 PDX1 C-terminal inhibiting factor 1
PDE6H phosphodiesterase 6H, cGMP-specific, cone, gamma
PHACTR3 phosphatase and actin regulator 3
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta
POLD3 polymerase (DNA-directed), delta 3, accessory subunit
PRLR prolactin receptor
PROK2 prokineticin 2
PTPRD protein tyrosine phosphatase, receptor type, D
RAB27A RAB27A, member RAS oncogene family
RBM11 RNA binding motif protein 11
RELT RELT tumor necrosis factor receptor
RESP18 regulated endocrine-specific protein 18
RFX8 RFX family member 8, lacking RFX DNA binding domain
RNF144A ring finger protein 144A
RREB1 ras responsive element binding protein 1
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SBF2-AS1 SBF2 antisense RNA 1
SCAF4 SR-related CTD-associated factor 4
SDAD1 SDA1 domain containing 1
SEC24D SEC24 family member D
SEPT10 septin 10
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1
SETD5 SET domain containing 5
SFTPC surfactant protein C
SHANK2-AS3 SHANK2 antisense RNA 3
SIK3 SIK family kinase 3
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7
SLC7A13 solute carrier family 7 (anionic amino acid transporter), member 13
SLC9B2 solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2
SMC6 structural maintenance of chromosomes 6
SNAPC5 small nuclear RNA activating complex, polypeptide 5, 19kDa
SNHG10 small nucleolar RNA host gene 10
SNORA11 small nucleolar RNA, H/ACA box 11
SNORA67 small nucleolar RNA, H/ACA box 67
SNORA79 small nucleolar RNA, H/ACA box 79
SNRNP25 small nuclear ribonucleoprotein 25kDa (U11/U12)
SNRNP40 small nuclear ribonucleoprotein 40kDa (U5)
SNX10 sorting nexin 10
SNX14 sorting nexin 14
SNX30 sorting nexin family member 30
SORBS2 sorbin and SH3 domain containing 2
SPDL1 spindle apparatus coiled-coil protein 1
SRCAP Snf2-related CREBBP activator protein
SSUH2 ssu-2 homolog (C. elegans)
STX3 syntaxin 3
TENM2 teneurin transmembrane protein 2
TLN2 talin 2
TMEM40 transmembrane protein 40
TMEM41A transmembrane protein 41A
TMEM68 transmembrane protein 68
TMEM9B TMEM9 domain family, member B
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFRSF19 tumor necrosis factor receptor superfamily, member 19
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast)
TRIM58 tripartite motif containing 58
TRPC6 transient receptor potential cation channel, subfamily C, member 6
TTC39C tetratricopeptide repeat domain 39C
UBASH3A ubiquitin associated and SH3 domain containing A
UFL1 UFM1-specific ligase 1
UNC5C unc-5 homolog C (C. elegans)
UVSSA UV-stimulated scaffold protein A
WDR5 WD repeat domain 5
XXYLT1 xyloside xylosyltransferase 1
ZBTB4 zinc finger and BTB domain containing 4
ZCCHC11 zinc finger, CCHC domain containing 11
ZNF385A zinc finger protein 385A