| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | peroxisome proliferator-activated receptor alpha|Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers; this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for this gene, although the full-length nature of only two has been determined. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 5465) |
| External Link | https://ncbi.nlm.nih.gov/gene/5465 |
| Similar Terms | |
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499 genes differentially expressed following the PPARA gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ZDHHC6 | zinc finger, DHHC-type containing 6 | 0.0227702 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0185083 |
| IFI44L | interferon-induced protein 44-like | 0.017633 |
| GNAS | GNAS complex locus | 0.0165913 |
| MX1 | MX dynamin-like GTPase 1 | 0.0161557 |
| FHL1 | four and a half LIM domains 1 | 0.0155883 |
| IFI44 | interferon-induced protein 44 | 0.0148807 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.013931 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | 0.0135194 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0133649 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0127841 |
| ASS1 | argininosuccinate synthase 1 | 0.0127618 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | 0.0126912 |
| MYBPC1 | myosin binding protein C, slow type | 0.0125171 |
| PROM1 | prominin 1 | 0.0124388 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.0120933 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0120836 |
| MX2 | MX dynamin-like GTPase 2 | 0.0117296 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0114854 |
| MAOB | monoamine oxidase B | 0.0110937 |
| HACD1 | 3-hydroxyacyl-CoA dehydratase 1 | 0.0110571 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.0107612 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 0.0106999 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | 0.010684 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.010558 |
| FABP4 | fatty acid binding protein 4, adipocyte | 0.0104643 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | 0.0104341 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0103472 |
| BST2 | bone marrow stromal cell antigen 2 | 0.0102997 |
| XAF1 | XIAP associated factor 1 | 0.0102655 |
| ANXA3 | annexin A3 | 0.0101823 |
| RTN2 | reticulon 2 | 0.00974282 |
| HSPB8 | heat shock 22kDa protein 8 | 0.00960109 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.00940768 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | 0.00939178 |
| ATP1A2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide | 0.0092254 |
| PLIN2 | perilipin 2 | 0.00911959 |
| LY6E | lymphocyte antigen 6 complex, locus E | 0.00910942 |
| HSPA1A | heat shock 70kDa protein 1A | 0.00910458 |
| LOX | lysyl oxidase | 0.00897145 |
| SVIL | supervillin | 0.00896859 |
| TNNC1 | troponin C type 1 (slow) | 0.00893533 |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 | 0.00889213 |
| MXI1 | MAX interactor 1, dimerization protein | 0.00886842 |
| PEG3 | paternally expressed 3 | 0.00886468 |
| FOLR1 | folate receptor 1 (adult) | 0.00886115 |
| MGLL | monoglyceride lipase | 0.00882777 |
| PAM | peptidylglycine alpha-amidating monooxygenase | 0.00881536 |
| RRAGD | Ras-related GTP binding D | 0.00875579 |
| GREB1 | growth regulation by estrogen in breast cancer 1 | 0.00871795 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.00871493 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.0086853 |
| C8ORF4 | chromosome 8 open reading frame 4 | 0.00864508 |
| KRT7 | keratin 7, type II | 0.00857381 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.00843158 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.00842515 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | 0.00839688 |
| SSPN | sarcospan | 0.00839251 |
| MFAP5 | microfibrillar associated protein 5 | 0.00838605 |
| NREP | neuronal regeneration related protein | 0.00837031 |
| CHGB | chromogranin B | 0.00836947 |
| SLN | sarcolipin | 0.00835322 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.00824432 |
| NCAM1 | neural cell adhesion molecule 1 | 0.00824303 |
| MN1 | meningioma (disrupted in balanced translocation) 1 | 0.00823896 |
| GOLGA8A | golgin A8 family, member A | 0.00822609 |
| CSRP2 | cysteine and glycine-rich protein 2 | 0.00821627 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.00816071 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 | 0.00814928 |
| CRYAB | crystallin, alpha B | 0.00812689 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.00810703 |
| KRT19 | keratin 19, type I | 0.00803186 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | 0.00797816 |
| DES | desmin | 0.00792205 |
| AOX1 | aldehyde oxidase 1 | 0.00788814 |
| EMX2 | empty spiracles homeobox 2 | 0.00785627 |
| CCN3 | cellular communication network factor 3 | 0.00784086 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | 0.00783147 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | 0.00779294 |
| MYL2 | myosin, light chain 2, regulatory, cardiac, slow | 0.00777658 |
| EPCAM | epithelial cell adhesion molecule | 0.00777148 |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) | 0.00776592 |
| EGFL6 | EGF-like-domain, multiple 6 | 0.0077519 |
| MEIS1 | Meis homeobox 1 | 0.00772583 |
| PDLIM3 | PDZ and LIM domain 3 | 0.00771949 |
| C3 | complement component 3 | 0.00769233 |
| IFRD2 | interferon-related developmental regulator 2 | 0.00766862 |
| FNBP1 | formin binding protein 1 | 0.00764333 |
| CKM | creatine kinase, muscle | 0.00762012 |
| SOBP | sine oculis binding protein homolog (Drosophila) | 0.00759452 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta | 0.00759211 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.00758323 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.00756063 |
| TRIM22 | tripartite motif containing 22 | 0.00755155 |
| MPPED2 | metallophosphoesterase domain containing 2 | 0.0075496 |
| MYOZ2 | myozenin 2 | 0.00753355 |
| RGS5 | regulator of G-protein signaling 5 | 0.00751571 |
| ITPKB | inositol-trisphosphate 3-kinase B | 0.00749584 |
| PODXL | podocalyxin-like | 0.00747868 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | 0.00747408 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 | 0.00742592 |
| MGP | matrix Gla protein | 0.00740565 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha | 0.00737701 |
| NRCAM | neuronal cell adhesion molecule | 0.00737446 |
| LRRN3 | leucine rich repeat neuronal 3 | 0.00735285 |
| LAMP3 | lysosomal-associated membrane protein 3 | 0.00733614 |
| MYL1 | myosin, light chain 1, alkali; skeletal, fast | 0.00727698 |
| SERPINB8 | serpin peptidase inhibitor, clade B (ovalbumin), member 8 | 0.00723096 |
| TDRD7 | tudor domain containing 7 | 0.00716904 |
| ABLIM1 | actin binding LIM protein 1 | 0.00713389 |
| TMOD1 | tropomodulin 1 | 0.00709259 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.00705854 |
| RBPMS | RNA binding protein with multiple splicing | 0.00702484 |
| TFRC | transferrin receptor | 0.00702292 |
| KLHL41 | kelch-like family member 41 | 0.00701386 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.00698708 |
| ST6GALNAC5 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 | 0.00697728 |
| ADIPOQ | adiponectin, C1Q and collagen domain containing | 0.00697448 |
| IRS2 | insulin receptor substrate 2 | 0.006951 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 | 0.00694406 |
| TTN | titin | 0.00689923 |
| ACKR3 | atypical chemokine receptor 3 | 0.00689297 |
| MEIS2 | Meis homeobox 2 | 0.00686864 |
| B3GALNT1 | beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) | 0.00686858 |
| LDB3 | LIM domain binding 3 | 0.00686148 |
| CRABP2 | cellular retinoic acid binding protein 2 | 0.00684473 |
| ASPN | asporin | 0.00682192 |
| POSTN | periostin, osteoblast specific factor | 0.00678896 |
| RHOBTB1 | Rho-related BTB domain containing 1 | 0.00678687 |
| MSRB2 | methionine sulfoxide reductase B2 | 0.00677259 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.00674094 |
| CFB | complement factor B | 0.00673486 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.00668611 |
| ACTA1 | actin, alpha 1, skeletal muscle | 0.00666692 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.00666534 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | 0.00665707 |
| HSPB7 | heat shock 27kDa protein family, member 7 (cardiovascular) | 0.00662318 |
| L1CAM | L1 cell adhesion molecule | 0.00659694 |
| GPC3 | glypican 3 | 0.00656621 |
| MAB21L1 | mab-21-like 1 (C. elegans) | 0.00656596 |
| DMD | dystrophin | 0.00656326 |
| RALB | v-ral simian leukemia viral oncogene homolog B | 0.00655406 |
| SAMHD1 | SAM domain and HD domain 1 | 0.00654678 |
| DOK5 | docking protein 5 | 0.00653306 |
| MYOT | myotilin | 0.00652794 |
| CASQ2 | calsequestrin 2 (cardiac muscle) | 0.00651735 |
| RBKS | ribokinase | 0.00641076 |
| PDZD2 | PDZ domain containing 2 | 0.00640731 |
| THBS4 | thrombospondin 4 | 0.00640455 |
| TNS1 | tensin 1 | 0.00639249 |
| CLDN10 | claudin 10 | 0.00639168 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | 0.00638513 |
| PDGFRL | platelet-derived growth factor receptor-like | 0.00638345 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.00637837 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.00636512 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.00634421 |
| MPO | myeloperoxidase | 0.00633842 |
| PCBP1 | poly(rC) binding protein 1 | 0.00633314 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | 0.00631405 |
| C14ORF132 | chromosome 14 open reading frame 132 | 0.00631198 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.00628616 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.00626169 |
| SYNM | synemin, intermediate filament protein | 0.00623666 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0062182 |
| RET | ret proto-oncogene | 0.00620634 |
| SFRP1 | secreted frizzled-related protein 1 | 0.00618052 |
| IGF1 | insulin-like growth factor 1 (somatomedin C) | 0.0061488 |
| TPM4 | tropomyosin 4 | 0.00614208 |
| DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 | 0.00613668 |
| GPX3 | glutathione peroxidase 3 | 0.00613513 |
| IRAK1 | interleukin-1 receptor-associated kinase 1 | 0.00612629 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.00612265 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.00609926 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | 0.0060761 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | 0.00607285 |
| FAM189A2 | family with sequence similarity 189, member A2 | 0.00604048 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.00603975 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | 0.00603621 |
| PRPF4 | pre-mRNA processing factor 4 | 0.00602449 |
| ENPEP | glutamyl aminopeptidase (aminopeptidase A) | 0.00601999 |
| OGN | osteoglycin | 0.00601379 |
| OXTR | oxytocin receptor | 0.00600229 |
| MYOF | myoferlin | 0.00593826 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | 0.00593147 |
| LAMA2 | laminin, alpha 2 | 0.0059207 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | 0.00592041 |
| ENO3 | enolase 3 (beta, muscle) | 0.00591365 |
| GOLM1 | golgi membrane protein 1 | 0.00588347 |
| CD93 | CD93 molecule | 0.00587422 |
| TCEAL2 | transcription elongation factor A (SII)-like 2 | 0.0058435 |
| NPR1 | natriuretic peptide receptor 1 | 0.00583085 |
| ATF3 | activating transcription factor 3 | 0.00582505 |
| PHF11 | PHD finger protein 11 | 0.00582482 |
| ANXA1 | annexin A1 | 0.00582167 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.00581993 |
| USP18 | ubiquitin specific peptidase 18 | 0.00579826 |
| MYO1C | myosin IC | 0.00577198 |
| TPM3 | tropomyosin 3 | 0.00576702 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.00576461 |
| ITIH5 | inter-alpha-trypsin inhibitor heavy chain family, member 5 | 0.00576244 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.00576063 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.0057342 |
| FMO2 | flavin containing monooxygenase 2 (non-functional) | 0.00573233 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.00571347 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.00570843 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.00569936 |
| WFDC2 | WAP four-disulfide core domain 2 | 0.00568131 |
| HLA-C | major histocompatibility complex, class I, C | 0.00566593 |
| DHTKD1 | dehydrogenase E1 and transketolase domain containing 1 | 0.0056655 |
| NIBAN1 | niban apoptosis regulator 1 | 0.00566493 |
| HIST1H2BD | histone cluster 1, H2bd | 0.00565861 |
| CAPN3 | calpain 3, (p94) | 0.00565829 |
| VLDLR | very low density lipoprotein receptor | 0.00564405 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.00561099 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.00560436 |
| VCL | vinculin | 0.00559363 |
| TNNI1 | troponin I type 1 (skeletal, slow) | 0.00558779 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0055728 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) | 0.00557007 |
| GAB2 | GRB2-associated binding protein 2 | 0.00554901 |
| MEOX2 | mesenchyme homeobox 2 | 0.00554559 |
| HLA-B | major histocompatibility complex, class I, B | 0.005545 |
| TNNC2 | troponin C type 2 (fast) | 0.0055174 |
| FOSL2 | FOS-like antigen 2 | 0.00551028 |
| MYH3 | myosin, heavy chain 3, skeletal muscle, embryonic | 0.00549086 |
| SMPX | small muscle protein, X-linked | 0.00547656 |
| MYOM1 | myomesin 1 | 0.00545626 |
| CRABP1 | cellular retinoic acid binding protein 1 | 0.00545059 |
| ADAMTSL3 | ADAMTS-like 3 | 0.00544905 |
| PCOLCE2 | procollagen C-endopeptidase enhancer 2 | 0.00542113 |
| PLIN1 | perilipin 1 | 0.00541708 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.00540917 |
| NKX2-1 | NK2 homeobox 1 | 0.00540394 |
| PKD1P1 | polycystic kidney disease 1 (autosomal dominant) pseudogene 1 | 0.00538602 |
| PDE8B | phosphodiesterase 8B | 0.00538568 |
| AOC3 | amine oxidase, copper containing 3 | 0.00538339 |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 | 0.00537473 |
| CHRDL1 | chordin-like 1 | 0.00536154 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 | 0.00535889 |
| PPP1R1A | protein phosphatase 1, regulatory (inhibitor) subunit 1A | 0.00535864 |
| PLP1 | proteolipid protein 1 | 0.00534894 |
| STON1 | stonin 1 | 0.0053433 |
| DST | dystonin | 0.00534128 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.00533679 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.00533232 |
| RBM39 | RNA binding motif protein 39 | 0.00532283 |
| SP110 | SP110 nuclear body protein | 0.00531059 |
| CLIC5 | chloride intracellular channel 5 | 0.00530441 |
| CDV3 | CDV3 homolog (mouse) | 0.00529925 |
| SRPX | sushi-repeat containing protein, X-linked | 0.00529464 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SYNGR3 | synaptogyrin 3 | -0.0191486 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0182891 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | -0.0138638 |
| JCHAIN | joining chain of multimeric IgA and IgM | -0.0136656 |
| MMP9 | matrix metallopeptidase 9 | -0.0134618 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.0131946 |
| SIRT3 | sirtuin 3 | -0.0131556 |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | -0.012436 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.0118634 |
| MMP12 | matrix metallopeptidase 12 | -0.0113583 |
| FGFR3 | fibroblast growth factor receptor 3 | -0.0110935 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | -0.0106084 |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | -0.0104762 |
| POU2AF1 | POU class 2 associating factor 1 | -0.0102538 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | -0.0100024 |
| CD8A | CD8a molecule | -0.0098123 |
| TPSAB1 | tryptase alpha/beta 1 | -0.0095391 |
| SH3BGRL | SH3 domain binding glutamate-rich protein like | -0.00950025 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.00927348 |
| CCL19 | chemokine (C-C motif) ligand 19 | -0.00900729 |
| TOX3 | TOX high mobility group box family member 3 | -0.00896948 |
| HSD11B1 | hydroxysteroid (11-beta) dehydrogenase 1 | -0.00887219 |
| IPO13 | importin 13 | -0.00876456 |
| UGT2B15 | UDP glucuronosyltransferase 2 family, polypeptide B15 | -0.0086534 |
| ADAMDEC1 | ADAM-like, decysin 1 | -0.00860064 |
| CA12 | carbonic anhydrase XII | -0.00857307 |
| APOD | apolipoprotein D | -0.00852753 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0084585 |
| IL7R | interleukin 7 receptor | -0.00842666 |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) | -0.00834614 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.00830862 |
| KRT1 | keratin 1, type II | -0.00824543 |
| IL18 | interleukin 18 | -0.00823471 |
| UGT2B17 | UDP glucuronosyltransferase 2 family, polypeptide B17 | -0.00819015 |
| CD79A | CD79a molecule, immunoglobulin-associated alpha | -0.0081772 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.00805606 |
| KRT15 | keratin 15, type I | -0.0079321 |
| PLBD1 | phospholipase B domain containing 1 | -0.00790217 |
| S100A9 | S100 calcium binding protein A9 | -0.00786469 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.00781847 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.00777794 |
| CLCA1 | chloride channel accessory 1 | -0.0076982 |
| CTSK | cathepsin K | -0.00767431 |
| LEFTY1 | left-right determination factor 1 | -0.00766175 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.00764515 |
| LOR | loricrin | -0.00761412 |
| ITGAV | integrin, alpha V | -0.00761077 |
| TNFRSF17 | tumor necrosis factor receptor superfamily, member 17 | -0.00758157 |
| GZMH | granzyme H (cathepsin G-like 2, protein h-CCPX) | -0.00747797 |
| GZMK | granzyme K (granzyme 3; tryptase II) | -0.00742708 |
| KRAS | Kirsten rat sarcoma viral oncogene homolog | -0.00737001 |
| RAB40B | RAB40B, member RAS oncogene family | -0.00735744 |
| CPA3 | carboxypeptidase A3 (mast cell) | -0.0073396 |
| KRT6B | keratin 6B, type II | -0.00733147 |
| GNLY | granulysin | -0.00730417 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.00725166 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -0.007094 |
| FRZB | frizzled-related protein | -0.00708502 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | -0.00706756 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | -0.00704608 |
| SDC1 | syndecan 1 | -0.00701504 |
| FXYD2 | FXYD domain containing ion transport regulator 2 | -0.00700505 |
| TPD52 | tumor protein D52 | -0.00695956 |
| DCK | deoxycytidine kinase | -0.0069208 |
| MAP7 | microtubule-associated protein 7 | -0.00688678 |
| MZB1 | marginal zone B and B1 cell-specific protein | -0.00682888 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | -0.00679542 |
| SLAMF7 | SLAM family member 7 | -0.00676913 |
| FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide | -0.00671854 |
| PKP1 | plakophilin 1 | -0.00668471 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0066604 |
| ECI2 | enoyl-CoA delta isomerase 2 | -0.0066556 |
| DSG1 | desmoglein 1 | -0.00660975 |
| STK17A | serine/threonine kinase 17a | -0.00659401 |
| TFF3 | trefoil factor 3 (intestinal) | -0.00656094 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | -0.00655798 |
| CST7 | cystatin F (leukocystatin) | -0.00655409 |
| CFTR | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) | -0.00652676 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | -0.00652144 |
| SPRR1B | small proline-rich protein 1B | -0.00648064 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.00644434 |
| CD19 | CD19 molecule | -0.00643935 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | -0.00643908 |
| ANO10 | anoctamin 10 | -0.00642454 |
| KRT5 | keratin 5, type II | -0.006415 |
| ACP5 | acid phosphatase 5, tartrate resistant | -0.00641458 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | -0.00637255 |
| RUFY3 | RUN and FYVE domain containing 3 | -0.00629118 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | -0.00627744 |
| LEF1 | lymphoid enhancer-binding factor 1 | -0.00626899 |
| NDUFA6 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa | -0.00623864 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.00622191 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.00621841 |
| ARG1 | arginase 1 | -0.0062165 |
| ABHD6 | abhydrolase domain containing 6 | -0.00617654 |
| TCF4 | transcription factor 4 | -0.00615848 |
| MCUB | mitochondrial calcium uniporter dominant negative subunit beta | -0.00613373 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | -0.00613349 |
| KRT81 | keratin 81, type II | -0.00612178 |
| TPST2 | tyrosylprotein sulfotransferase 2 | -0.00611962 |
| BLNK | B-cell linker | -0.00610369 |
| COL6A2 | collagen, type VI, alpha 2 | -0.00608889 |
| HLA-DQB2 | major histocompatibility complex, class II, DQ beta 2 | -0.00607194 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | -0.00601076 |
| KLRD1 | killer cell lectin-like receptor subfamily D, member 1 | -0.00599978 |
| KRT14 | keratin 14, type I | -0.00597128 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.00596206 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.00593395 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.00592999 |
| JMJD6 | jumonji domain containing 6 | -0.00592159 |
| POF1B | premature ovarian failure, 1B | -0.00591494 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | -0.0059005 |
| LCK | LCK proto-oncogene, Src family tyrosine kinase | -0.00590009 |
| NVL | nuclear VCP-like | -0.00588386 |
| SFN | stratifin | -0.00587702 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.00587649 |
| S100A2 | S100 calcium binding protein A2 | -0.00585817 |
| TWF1 | twinfilin actin binding protein 1 | -0.00582582 |
| FAM162A | family with sequence similarity 162, member A | -0.00580889 |
| PHTF2 | putative homeodomain transcription factor 2 | -0.00579099 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | -0.00578947 |
| PDZK1IP1 | PDZK1 interacting protein 1 | -0.00578852 |
| HLA-DOB | major histocompatibility complex, class II, DO beta | -0.00578727 |
| MXRA7 | matrix-remodelling associated 7 | -0.00578669 |
| HEPH | hephaestin | -0.00577971 |
| PIGR | polymeric immunoglobulin receptor | -0.00576684 |
| ARSL | arylsulfatase L | -0.00575708 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -0.00575492 |
| HIP1R | huntingtin interacting protein 1 related | -0.00575378 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) | -0.00573434 |
| CSTA | cystatin A (stefin A) | -0.00573255 |
| CDSN | corneodesmosin | -0.00572624 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.00570666 |
| CALML3 | calmodulin-like 3 | -0.00569762 |
| NDUFA4L2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 | -0.00569591 |
| PERP | PERP, TP53 apoptosis effector | -0.00568893 |
| KLRB1 | killer cell lectin-like receptor subfamily B, member 1 | -0.00566967 |
| SOCS1 | suppressor of cytokine signaling 1 | -0.00565054 |
| PRF1 | perforin 1 (pore forming protein) | -0.00563243 |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O | -0.00561803 |
| LSM7 | LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.00561257 |
| PKP3 | plakophilin 3 | -0.00560771 |
| KAT2B | K(lysine) acetyltransferase 2B | -0.00560716 |
| AUTS2 | autism susceptibility candidate 2 | -0.00558497 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.00556959 |
| KRT6A | keratin 6A, type II | -0.00555966 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | -0.00555789 |
| SIDT2 | SID1 transmembrane family, member 2 | -0.00555366 |
| PI3 | peptidase inhibitor 3, skin-derived | -0.00553909 |
| PRKCZ | protein kinase C, zeta | -0.00552973 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.00552449 |
| NOX1 | NADPH oxidase 1 | -0.00551741 |
| HOPX | HOP homeobox | -0.00551236 |
| C1QB | complement component 1, q subcomponent, B chain | -0.00551158 |
| APRT | adenine phosphoribosyltransferase | -0.0055029 |
| PFKL | phosphofructokinase, liver | -0.00546278 |
| KLRK1 | killer cell lectin-like receptor subfamily K, member 1 | -0.00545916 |
| CLEC10A | C-type lectin domain family 10, member A | -0.00545186 |
| PAX5 | paired box 5 | -0.00544387 |
| LCE2B | late cornified envelope 2B | -0.00543833 |
| TP63 | tumor protein p63 | -0.0054321 |
| MMP1 | matrix metallopeptidase 1 | -0.00542975 |
| SSX1 | synovial sarcoma, X breakpoint 1 | -0.00542867 |
| LYRM4 | LYR motif containing 4 | -0.00542272 |
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 | -0.00540257 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) | -0.00539914 |
| NDRG1 | N-myc downstream regulated 1 | -0.00539233 |
| C1ORF54 | chromosome 1 open reading frame 54 | -0.00539091 |
| LY96 | lymphocyte antigen 96 | -0.0053864 |
| FBXO3 | F-box protein 3 | -0.00538213 |
| ATG3 | autophagy related 3 | -0.00538042 |
| SPRR1A | small proline-rich protein 1A | -0.00537213 |
| ACSM3 | acyl-CoA synthetase medium-chain family member 3 | -0.0053634 |
| CALML5 | calmodulin-like 5 | -0.00536287 |
| PENK | proenkephalin | -0.00534407 |
| XCL1 | chemokine (C motif) ligand 1 | -0.00533743 |
| KLK1 | kallikrein 1 | -0.00532132 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -0.0053128 |
| TMEM106B | transmembrane protein 106B | -0.00531228 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | -0.00530483 |
| NKX2-2 | NK2 homeobox 2 | -0.00529753 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | -0.00528773 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | -0.0052758 |
| S100A8 | S100 calcium binding protein A8 | -0.00527506 |
| RTN1 | reticulon 1 | -0.00525896 |
| C1R | complement component 1, r subcomponent | -0.0052564 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | -0.00525387 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | -0.00525077 |
| GNPTAB | N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits | -0.00524738 |
| GAS6 | growth arrest-specific 6 | -0.00524731 |
| HPR | haptoglobin-related protein | -0.00524332 |
| PCDH9 | protocadherin 9 | -0.00523764 |
| GM2A | GM2 ganglioside activator | -0.00521819 |
| THY1 | Thy-1 cell surface antigen | -0.00519399 |
| GPX2 | glutathione peroxidase 2 | -0.0051818 |
| YTHDF2 | YTH N(6)-methyladenosine RNA binding protein 2 | -0.00517931 |
| SRPK2 | SRSF protein kinase 2 | -0.00517698 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | -0.00517388 |
| TP53TG1 | TP53 target 1 (non-protein coding) | -0.00516348 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | -0.00515817 |
| GEM | GTP binding protein overexpressed in skeletal muscle | -0.00515272 |
| OPN3 | opsin 3 | -0.00515263 |
| PSMD13 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 | -0.00513944 |
| STEAP3 | STEAP family member 3, metalloreductase | -0.00513139 |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | -0.00512361 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | -0.00511896 |
| MPC2 | mitochondrial pyruvate carrier 2 | -0.00508066 |
| SPON2 | spondin 2, extracellular matrix protein | -0.00508058 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.00507918 |
| AZF1 | azoospermia factor 1 | -0.00506733 |
| TRAPPC2L | trafficking protein particle complex 2-like | -0.00506216 |
| AREG | amphiregulin | -0.00504212 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.00504016 |
| LCN2 | lipocalin 2 | -0.00503637 |
| LY75 | lymphocyte antigen 75 | -0.00502488 |
| STAT4 | signal transducer and activator of transcription 4 | -0.00501285 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | -0.00500802 |
| MYO1D | myosin ID | -0.00499714 |
| TNFSF13B | tumor necrosis factor (ligand) superfamily, member 13b | -0.00499047 |
| ANO3 | anoctamin 3 | -0.00498616 |
| HSPB11 | heat shock protein family B (small), member 11 | -0.00498244 |
| PTGDR | prostaglandin D2 receptor (DP) | -0.00497991 |
| AKR1C4 | aldo-keto reductase family 1, member C4 | -0.00497605 |
| VRK1 | vaccinia related kinase 1 | -0.00496652 |
| SUCO | SUN domain containing ossification factor | -0.00495903 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.00495332 |
| C4BPA | complement component 4 binding protein, alpha | -0.00494061 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 | -0.00493429 |
| NDN | necdin, melanoma antigen (MAGE) family member | -0.00492713 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 | -0.00492704 |
| GLS | glutaminase | -0.0049217 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.00491399 |
| IRF6 | interferon regulatory factor 6 | -0.00491108 |
| ALOX15B | arachidonate 15-lipoxygenase, type B | -0.00489509 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | -0.00487479 |
| TOR3A | torsin family 3, member A | -0.00486213 |
| SGPP1 | sphingosine-1-phosphate phosphatase 1 | -0.00486171 |
| C1QA | complement component 1, q subcomponent, A chain | -0.00484257 |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 | -0.00483127 |
| AKR7A3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) | -0.00482589 |
| PAPSS1 | 3'-phosphoadenosine 5'-phosphosulfate synthase 1 | -0.00482287 |
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 | -0.00482098 |
| RNF43 | ring finger protein 43 | -0.00482024 |
| WASHC3 | WASH complex subunit 3 | -0.00481846 |
| ITIH1 | inter-alpha-trypsin inhibitor heavy chain 1 | -0.00480864 |
| DSC1 | desmocollin 1 | -0.00480038 |
| PLD3 | phospholipase D family, member 3 | -0.00479436 |
| SERINC5 | serine incorporator 5 | -0.00478988 |
| SGMS1 | sphingomyelin synthase 1 | -0.00478104 |
