| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | peroxisome proliferator-activated receptor delta|This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. PPARs are nuclear hormone receptors that bind peroxisome proliferators and control the size and number of peroxisomes produced by cells. PPARs mediate a variety of biological processes, and may be involved in the development of several chronic diseases, including diabetes, obesity, atherosclerosis, and cancer. This protein is a potent inhibitor of ligand-induced transcription activity of PPAR alpha and PPAR gamma. It may function as an integrator of transcription repression and nuclear receptor signaling. The expression of this gene is found to be elevated in colorectal cancer cells. The elevated expression can be repressed by adenomatosis polyposis coli (APC), a tumor suppressor protein related to APC/beta-catenin signaling pathway. Knockout studies in mice suggested the role of this protein in myelination of the corpus callosum, lipid metabolism, and epidermal cell proliferation. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2010] (NCBI Entrez Gene Database, 5467) |
| External Link | https://ncbi.nlm.nih.gov/gene/5467 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the PPARD gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ADIRF | adipogenesis regulatory factor | 0.0106075 |
| XIC | X chromosome inactivation center | 0.00990926 |
| HSPA1A | heat shock 70kDa protein 1A | 0.00840128 |
| FABP4 | fatty acid binding protein 4, adipocyte | 0.00807561 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.00794748 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.0079314 |
| PEG10 | paternally expressed 10 | 0.00780024 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 0.00721253 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.00680554 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | 0.00676919 |
| EXT1 | exostosin glycosyltransferase 1 | 0.00664616 |
| LTF | lactotransferrin | 0.00656006 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 0.00653166 |
| LMCD1 | LIM and cysteine-rich domains 1 | 0.00651872 |
| MXRA7 | matrix-remodelling associated 7 | 0.00650416 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | 0.00649324 |
| ZNF395 | zinc finger protein 395 | 0.00641694 |
| MYBPC1 | myosin binding protein C, slow type | 0.00629023 |
| PLIN2 | perilipin 2 | 0.00628694 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.00628504 |
| CRYAB | crystallin, alpha B | 0.00627401 |
| EFHD1 | EF-hand domain family, member D1 | 0.00617192 |
| PLAAT3 | phospholipase A and acyltransferase 3 | 0.00610626 |
| HSPB8 | heat shock 22kDa protein 8 | 0.00600765 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.00592531 |
| SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) | 0.005924 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.00589347 |
| DYNLL1 | dynein, light chain, LC8-type 1 | 0.00587893 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) | 0.00583232 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.00566039 |
| C8ORF4 | chromosome 8 open reading frame 4 | 0.00556763 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.00554316 |
| PGC | progastricsin (pepsinogen C) | 0.00551088 |
| COG7 | component of oligomeric golgi complex 7 | 0.00549925 |
| TNS3 | tensin 3 | 0.00548577 |
| MTCL1 | microtubule crosslinking factor 1 | 0.00547384 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | 0.00536468 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.00535211 |
| THBS1 | thrombospondin 1 | 0.00533375 |
| PCOLCE2 | procollagen C-endopeptidase enhancer 2 | 0.00533081 |
| RIN2 | Ras and Rab interactor 2 | 0.00532851 |
| MT1E | metallothionein 1E | 0.00526682 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | 0.00520264 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | 0.00520179 |
| BIK | BCL2-interacting killer (apoptosis-inducing) | 0.00518141 |
| SMAD7 | SMAD family member 7 | 0.00517511 |
| RCAN1 | regulator of calcineurin 1 | 0.00515213 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 0.00513901 |
| MRPS30 | mitochondrial ribosomal protein S30 | 0.0051337 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.00511033 |
| PNMA2 | paraneoplastic Ma antigen 2 | 0.00509992 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | 0.00508518 |
| CCNF | cyclin F | 0.0050836 |
| PENK | proenkephalin | 0.0050826 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.0050763 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | 0.00501454 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.00498155 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | 0.00495842 |
| GNAS | GNAS complex locus | 0.00495106 |
| TARP | TCR gamma alternate reading frame protein | 0.00495009 |
| ELF5 | E74-like factor 5 (ets domain transcription factor) | 0.00494568 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | 0.00492976 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.00492199 |
| GUSBP3 | glucuronidase, beta pseudogene 3 | 0.00491067 |
| DUSP2 | dual specificity phosphatase 2 | 0.00490977 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | 0.0048789 |
| ALB | albumin | 0.00485672 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | 0.00483453 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | 0.0048158 |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 | 0.00478069 |
| TSC22D1 | TSC22 domain family, member 1 | 0.00476838 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase | 0.00476337 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | 0.00475864 |
| IFIT5 | interferon-induced protein with tetratricopeptide repeats 5 | 0.00471356 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.00471114 |
| JADE3 | jade family PHD finger 3 | 0.0046991 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | 0.00469905 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | 0.00469274 |
| NOTCH1 | notch 1 | 0.00465563 |
| PITX3 | paired-like homeodomain 3 | 0.00465472 |
| PON3 | paraoxonase 3 | 0.00460546 |
| HIST1H2BD | histone cluster 1, H2bd | 0.00460064 |
| TYRP1 | tyrosinase-related protein 1 | 0.00457552 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | 0.00455298 |
| CRABP1 | cellular retinoic acid binding protein 1 | 0.00448367 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 | 0.00447166 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | 0.00447123 |
| CAVIN3 | caveolae associated protein 3 | 0.0044642 |
| HACD1 | 3-hydroxyacyl-CoA dehydratase 1 | 0.00446088 |
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 | 0.00445488 |
| CADM1 | cell adhesion molecule 1 | 0.00444191 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | 0.00442863 |
| STK26 | serine/threonine protein kinase 26 | 0.00440485 |
| LDB3 | LIM domain binding 3 | 0.00435305 |
| SGCE | sarcoglycan, epsilon | 0.00434704 |
| UQCR11 | ubiquinol-cytochrome c reductase, complex III subunit XI | 0.00434617 |
| PLA1A | phospholipase A1 member A | 0.0043394 |
| COX7B | cytochrome c oxidase subunit VIIb | 0.00430277 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.00428503 |
| MAGT1 | magnesium transporter 1 | 0.00427691 |
| TAC1 | tachykinin, precursor 1 | 0.00425728 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.00423956 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.00423444 |
| COX7A2 | cytochrome c oxidase subunit VIIa polypeptide 2 (liver) | 0.00423132 |
| RGS4 | regulator of G-protein signaling 4 | 0.00421723 |
| PIP | prolactin-induced protein | 0.00420193 |
| KCNE4 | potassium channel, voltage gated subfamily E regulatory beta subunit 4 | 0.00420075 |
| MMP7 | matrix metallopeptidase 7 | 0.00419426 |
| ELAPOR1 | endosome-lysosome associated apoptosis and autophagy regulator 1 | 0.00418071 |
| SPRY2 | sprouty homolog 2 (Drosophila) | 0.00417947 |
| PLEKHM1 | pleckstrin homology domain containing, family M (with RUN domain) member 1 | 0.00417468 |
| TSPO | translocator protein (18kDa) | 0.00416703 |
| SEMA6A | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A | 0.00416384 |
| ANPEP | alanyl (membrane) aminopeptidase | 0.0041521 |
| ABLIM1 | actin binding LIM protein 1 | 0.00414684 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | 0.00414457 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.00413887 |
| BCL2A1 | BCL2-related protein A1 | 0.00413381 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 0.00412402 |
| RIPOR2 | RHO family interacting cell polarization regulator 2 | 0.00412311 |
| HOXC10 | homeobox C10 | 0.00411111 |
| GCH1 | GTP cyclohydrolase 1 | 0.00408545 |
| GGT1 | gamma-glutamyltransferase 1 | 0.00406364 |
| SPON1 | spondin 1, extracellular matrix protein | 0.00406118 |
| FGF1 | fibroblast growth factor 1 (acidic) | 0.00401477 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.00399291 |
| CHKA | choline kinase alpha | 0.00398401 |
| QDPR | quinoid dihydropteridine reductase | 0.00398117 |
| GPER1 | G protein-coupled estrogen receptor 1 | 0.00396057 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | 0.00395735 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | 0.00394203 |
| BAMBI | BMP and activin membrane-bound inhibitor | 0.00394091 |
| SQLE | squalene epoxidase | 0.0039404 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | 0.00393226 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.00392985 |
| SPIB | Spi-B transcription factor (Spi-1/PU.1 related) | 0.00392487 |
| CCN3 | cellular communication network factor 3 | 0.00391972 |
| MX2 | MX dynamin-like GTPase 2 | 0.00391265 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | 0.00391065 |
| SOX10 | SRY (sex determining region Y)-box 10 | 0.00390066 |
| SMAD6 | SMAD family member 6 | 0.00389918 |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit | 0.00389883 |
| AHR | aryl hydrocarbon receptor | 0.0038959 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | 0.00387501 |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa | 0.00387458 |
| WASL | Wiskott-Aldrich syndrome-like | 0.00387134 |
| DNM1L | dynamin 1-like | 0.00386539 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 | 0.00386387 |
| MID1 | midline 1 | 0.00385408 |
| IER5 | immediate early response 5 | 0.00385083 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.00384863 |
| SST | somatostatin | 0.00383824 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.00383667 |
| CES1 | carboxylesterase 1 | 0.00383613 |
| POLR2D | polymerase (RNA) II (DNA directed) polypeptide D | 0.00383094 |
| ANK2 | ankyrin 2, neuronal | 0.00382303 |
| MEF2C | myocyte enhancer factor 2C | 0.00381642 |
| IL32 | interleukin 32 | 0.00381296 |
| PPP1R16B | protein phosphatase 1, regulatory subunit 16B | 0.00380692 |
| IRS2 | insulin receptor substrate 2 | 0.00379125 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.00377389 |
| TRIB2 | tribbles pseudokinase 2 | 0.0037671 |
| INTS6 | integrator complex subunit 6 | 0.0037662 |
| STK10 | serine/threonine kinase 10 | 0.00376593 |
| NNMT | nicotinamide N-methyltransferase | 0.00376018 |
| RBM34 | RNA binding motif protein 34 | 0.00375478 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0037208 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.00371931 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.00370725 |
| TKTL1 | transketolase-like 1 | 0.00369716 |
| CLU | clusterin | 0.00368826 |
| CARD10 | caspase recruitment domain family, member 10 | 0.00368559 |
| MRPL13 | mitochondrial ribosomal protein L13 | 0.00368471 |
| RPS27L | ribosomal protein S27-like | 0.00368391 |
| MBL2 | mannose-binding lectin (protein C) 2, soluble | 0.00367138 |
| AMACR | alpha-methylacyl-CoA racemase | 0.00367046 |
| ABCB1 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 | 0.00367041 |
| DAPK1 | death-associated protein kinase 1 | 0.00366974 |
| GPX1 | glutathione peroxidase 1 | 0.00366795 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 0.00365363 |
| PPIF | peptidylprolyl isomerase F | 0.00365363 |
| IL17RB | interleukin 17 receptor B | 0.00364523 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | 0.00363946 |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 | 0.00363306 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.00362355 |
| PLP1 | proteolipid protein 1 | 0.00361149 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | 0.00360955 |
| PADI2 | peptidyl arginine deiminase, type II | 0.00360637 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') | 0.00360184 |
| TNIK | TRAF2 and NCK interacting kinase | 0.00359301 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | 0.00358793 |
| HOMER1 | homer scaffolding protein 1 | 0.00358336 |
| MIA | melanoma inhibitory activity | 0.00357731 |
| TMEM131L | transmembrane 131 like | 0.00357728 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | 0.00357568 |
| ZNF652 | zinc finger protein 652 | 0.00357006 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | 0.00355708 |
| TSC22D2 | TSC22 domain family, member 2 | 0.00355498 |
| PTEN | phosphatase and tensin homolog | 0.00354674 |
| SNRPG | small nuclear ribonucleoprotein polypeptide G | 0.00354614 |
| FASTKD5 | FAST kinase domains 5 | 0.00354107 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0035391 |
| CCNA1 | cyclin A1 | 0.00353607 |
| ZNF264 | zinc finger protein 264 | 0.00353028 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.00352591 |
| EIF1AX | eukaryotic translation initiation factor 1A, X-linked | 0.00352452 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.00351465 |
| GMFB | glia maturation factor, beta | 0.00350417 |
| GPRC5B | G protein-coupled receptor, class C, group 5, member B | 0.00350262 |
| COL9A3 | collagen, type IX, alpha 3 | 0.00349965 |
| CD70 | CD70 molecule | 0.00349679 |
| RRAGC | Ras-related GTP binding C | 0.00348435 |
| FGF13 | fibroblast growth factor 13 | 0.00348395 |
| PRKCZ | protein kinase C, zeta | 0.00347512 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | 0.00347201 |
| STAP2 | signal transducing adaptor family member 2 | 0.00346467 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.00346061 |
| PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor | 0.00346022 |
| ATOX1 | antioxidant 1 copper chaperone | 0.00343458 |
| CTSH | cathepsin H | 0.00343312 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.00343233 |
| TMEM100 | transmembrane protein 100 | 0.00343172 |
| ROPN1B | rhophilin associated tail protein 1B | 0.00342942 |
| COL2A1 | collagen, type II, alpha 1 | 0.00342523 |
| PDZK1 | PDZ domain containing 1 | 0.00342222 |
| ZNF593 | zinc finger protein 593 | 0.00341763 |
| ANKRD28 | ankyrin repeat domain 28 | 0.00341242 |
| NTAQ1 | N-terminal glutamine amidase 1 | 0.00339857 |
| RND3 | Rho family GTPase 3 | 0.00339454 |
| MPPED2 | metallophosphoesterase domain containing 2 | 0.00339018 |
| SLIRP | SRA stem-loop interacting RNA binding protein | 0.00338081 |
| UXT | ubiquitously-expressed, prefoldin-like chaperone | 0.00337229 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.003371 |
| SCN3A | sodium channel, voltage gated, type III alpha subunit | 0.00337086 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 0.00336017 |
| CLDN8 | claudin 8 | 0.00335915 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.00335218 |
| FHL1 | four and a half LIM domains 1 | 0.00334543 |
| HPN | hepsin | 0.00334373 |
| AGTR1 | angiotensin II receptor, type 1 | 0.00334152 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | 0.00334125 |
| ARF3 | ADP-ribosylation factor 3 | 0.00334008 |
| ADIPOQ | adiponectin, C1Q and collagen domain containing | 0.00332729 |
| DUSP5 | dual specificity phosphatase 5 | 0.0033261 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | 0.00332373 |
| LPXN | leupaxin | 0.00332339 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.0033207 |
| TPST2 | tyrosylprotein sulfotransferase 2 | 0.00331616 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.00331378 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.00330694 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0183505 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.0118082 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.0105876 |
| NELL2 | NEL-like 2 (chicken) | -0.00917525 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | -0.00888576 |
| S100A7 | S100 calcium binding protein A7 | -0.00849545 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.00829475 |
| S100A9 | S100 calcium binding protein A9 | -0.00820684 |
| PI3 | peptidase inhibitor 3, skin-derived | -0.0076581 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | -0.00725749 |
| CD99 | CD99 molecule | -0.00725481 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.00711594 |
| S100A8 | S100 calcium binding protein A8 | -0.00708358 |
| CNPY3 | canopy FGF signaling regulator 3 | -0.00708259 |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 | -0.00708215 |
| TADA2A | transcriptional adaptor 2A | -0.00687334 |
| SELENBP1 | selenium binding protein 1 | -0.00674486 |
| SPRR1B | small proline-rich protein 1B | -0.00673902 |
| COL18A1 | collagen, type XVIII, alpha 1 | -0.00657118 |
| RAB25 | RAB25, member RAS oncogene family | -0.00655675 |
| KRT1 | keratin 1, type II | -0.00627696 |
| LYZ | lysozyme | -0.0061816 |
| AQP3 | aquaporin 3 (Gill blood group) | -0.00614747 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.00603574 |
| JUP | junction plakoglobin | -0.00599421 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.00599084 |
| CAST | calpastatin | -0.00597792 |
| CLTB | clathrin, light chain B | -0.00586713 |
| SPRR1A | small proline-rich protein 1A | -0.00581313 |
| PLAU | plasminogen activator, urokinase | -0.0057887 |
| LCN2 | lipocalin 2 | -0.0056642 |
| PSAT1 | phosphoserine aminotransferase 1 | -0.00559019 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -0.00558937 |
| MELK | maternal embryonic leucine zipper kinase | -0.00554486 |
| MMP10 | matrix metallopeptidase 10 | -0.00535454 |
| GBP1 | guanylate binding protein 1, interferon-inducible | -0.00531021 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | -0.00527547 |
| HCRT | hypocretin (orexin) neuropeptide precursor | -0.00520349 |
| NID1 | nidogen 1 | -0.00519836 |
| HOXB7 | homeobox B7 | -0.00519176 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.00516835 |
| KRT6A | keratin 6A, type II | -0.00514734 |
| KRT15 | keratin 15, type I | -0.00513404 |
| TMEM45A | transmembrane protein 45A | -0.0051291 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | -0.00506886 |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O | -0.00505514 |
| CTSZ | cathepsin Z | -0.00504826 |
| ANXA1 | annexin A1 | -0.00503299 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.00500011 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -0.00499842 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | -0.00499471 |
| ELP1 | elongator acetyltransferase complex subunit 1 | -0.00498852 |
| KLHDC2 | kelch domain containing 2 | -0.00495427 |
| CBS | cystathionine-beta-synthase | -0.00493706 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.00492369 |
| MMP12 | matrix metallopeptidase 12 | -0.00487022 |
| UGT2B17 | UDP glucuronosyltransferase 2 family, polypeptide B17 | -0.00483502 |
| SFN | stratifin | -0.0048009 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | -0.00476514 |
| TBC1D9B | TBC1 domain family, member 9B (with GRAM domain) | -0.00475647 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -0.0047523 |
| HOXB6 | homeobox B6 | -0.00474873 |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | -0.00474871 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | -0.00468341 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | -0.00468158 |
| DENND2D | DENN/MADD domain containing 2D | -0.00467799 |
| A2M | alpha-2-macroglobulin | -0.00466483 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.00465832 |
| COL1A2 | collagen, type I, alpha 2 | -0.00458241 |
| STC1 | stanniocalcin 1 | -0.00458237 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.00457002 |
| PGD | phosphogluconate dehydrogenase | -0.00454446 |
| PRDX2 | peroxiredoxin 2 | -0.00452421 |
| C1QB | complement component 1, q subcomponent, B chain | -0.00447682 |
| BAG3 | BCL2-associated athanogene 3 | -0.00445993 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.00445764 |
| DSG1 | desmoglein 1 | -0.00444494 |
| FBXO21 | F-box protein 21 | -0.00442746 |
| GAS6 | growth arrest-specific 6 | -0.00441859 |
| LEF1 | lymphoid enhancer-binding factor 1 | -0.00441698 |
| KRT6B | keratin 6B, type II | -0.00438843 |
| SPRR2B | small proline-rich protein 2B | -0.00438711 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0043846 |
| NBPF10 | neuroblastoma breakpoint family, member 10 | -0.00437789 |
| G0S2 | G0/G1 switch 2 | -0.00436048 |
| TWSG1 | twisted gastrulation BMP signaling modulator 1 | -0.00435401 |
| PERP | PERP, TP53 apoptosis effector | -0.00433317 |
| PXDN | peroxidasin | -0.00433146 |
| WLS | wntless Wnt ligand secretion mediator | -0.00432907 |
| HOXB2 | homeobox B2 | -0.00432298 |
| AARS1 | alanyl-tRNA synthetase 1 | -0.00428635 |
| GBP2 | guanylate binding protein 2, interferon-inducible | -0.00423689 |
| PFKL | phosphofructokinase, liver | -0.00421237 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | -0.00420811 |
| DPM3 | dolichyl-phosphate mannosyltransferase polypeptide 3 | -0.00420736 |
| FOXF1 | forkhead box F1 | -0.00420643 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.00415941 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.00415628 |
| POU4F1 | POU class 4 homeobox 1 | -0.00414887 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.00414854 |
| PKP1 | plakophilin 1 | -0.0041428 |
| KYNU | kynureninase | -0.00412184 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | -0.00411474 |
| RGS5 | regulator of G-protein signaling 5 | -0.00409689 |
| WDR7 | WD repeat domain 7 | -0.00409644 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.00408815 |
| SLC4A1 | solute carrier family 4 (anion exchanger), member 1 (Diego blood group) | -0.00406077 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -0.00405851 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | -0.00405657 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.00405276 |
| AGPAT1 | 1-acylglycerol-3-phosphate O-acyltransferase 1 | -0.00404218 |
| CPOX | coproporphyrinogen oxidase | -0.00403904 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.00403243 |
| LY6D | lymphocyte antigen 6 complex, locus D | -0.00400877 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | -0.00397415 |
| TMSB15A | thymosin beta 15a | -0.00397173 |
| NMU | neuromedin U | -0.0039632 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | -0.00395028 |
| ELANE | elastase, neutrophil expressed | -0.003947 |
| FLOT1 | flotillin 1 | -0.00394164 |
| VSNL1 | visinin-like 1 | -0.00393387 |
| PRAME | preferentially expressed antigen in melanoma | -0.00393262 |
| CD209 | CD209 molecule | -0.00391007 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | -0.00390557 |
| GYPC | glycophorin C (Gerbich blood group) | -0.00390301 |
| FOCAD | focadhesin | -0.00389763 |
| LYPD3 | LY6/PLAUR domain containing 3 | -0.00387997 |
| KRT16 | keratin 16, type I | -0.00387421 |
| NREP | neuronal regeneration related protein | -0.00387257 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | -0.00386961 |
| MCOLN1 | mucolipin 1 | -0.00386608 |
| CALML3 | calmodulin-like 3 | -0.00385321 |
| CFH | complement factor H | -0.00384358 |
| PTK2 | protein tyrosine kinase 2 | -0.00383779 |
| SERINC5 | serine incorporator 5 | -0.00382978 |
| GNE | glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase | -0.00382543 |
| LTB | lymphotoxin beta (TNF superfamily, member 3) | -0.00382331 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.00382287 |
| PTGS1 | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) | -0.00381972 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.00381876 |
| SUN1 | Sad1 and UNC84 domain containing 1 | -0.00380202 |
| TNC | tenascin C | -0.00378907 |
| HNRNPA0 | heterogeneous nuclear ribonucleoprotein A0 | -0.00378885 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.00378663 |
| HSPA13 | heat shock protein 70kDa family, member 13 | -0.00378201 |
| HBD | hemoglobin, delta | -0.00377996 |
| SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 | -0.00376701 |
| HCLS1 | hematopoietic cell-specific Lyn substrate 1 | -0.00376345 |
| ELAVL1 | ELAV like RNA binding protein 1 | -0.00374105 |
| VPS52 | vacuolar protein sorting 52 homolog (S. cerevisiae) | -0.00374002 |
| IVNS1ABP | influenza virus NS1A binding protein | -0.00373816 |
| TMPRSS4 | transmembrane protease, serine 4 | -0.00372478 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 | -0.00371381 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.00370631 |
| LOR | loricrin | -0.00370237 |
| BLNK | B-cell linker | -0.00369511 |
| RGCC | regulator of cell cycle | -0.0036838 |
| PTPN2 | protein tyrosine phosphatase, non-receptor type 2 | -0.00368077 |
| RNASE6 | ribonuclease, RNase A family, k6 | -0.00367421 |
| INAVA | innate immunity activator | -0.00366299 |
| MEIS1 | Meis homeobox 1 | -0.00366083 |
| ITGA4 | integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) | -0.00365754 |
| CDSN | corneodesmosin | -0.00364883 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A | -0.0036391 |
| RHCG | Rh family, C glycoprotein | -0.0036235 |
| SNX13 | sorting nexin 13 | -0.00362154 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | -0.00361108 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.00360215 |
| SPG11 | spastic paraplegia 11 (autosomal recessive) | -0.00360188 |
| NTS | neurotensin | -0.00359648 |
| CCL13 | chemokine (C-C motif) ligand 13 | -0.00358435 |
| IMMT | inner membrane protein, mitochondrial | -0.00357448 |
| PNN | pinin, desmosome associated protein | -0.00357198 |
| BAG6 | BCL2-associated athanogene 6 | -0.00356044 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.00355742 |
| ZBED1 | zinc finger, BED-type containing 1 | -0.0035558 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | -0.00355561 |
| HIPK1 | homeodomain interacting protein kinase 1 | -0.00355209 |
| CAV2 | caveolin 2 | -0.00354634 |
| HMGA1 | high mobility group AT-hook 1 | -0.00354217 |
| BLVRB | biliverdin reductase B | -0.00354102 |
| CSNK2B | casein kinase 2, beta polypeptide | -0.00353515 |
| RREB1 | ras responsive element binding protein 1 | -0.00352694 |
| KLF1 | Kruppel-like factor 1 (erythroid) | -0.00352279 |
| CRISP3 | cysteine-rich secretory protein 3 | -0.0035207 |
| GALC | galactosylceramidase | -0.00351793 |
| ACVR1B | activin A receptor, type IB | -0.00350901 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.0034881 |
| ABITRAM | actin binding transcription modulator | -0.00348548 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.00348408 |
| NDUFA4L2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 | -0.00348228 |
| TBC1D31 | TBC1 domain family, member 31 | -0.00347933 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.00347413 |
| PSIP1 | PC4 and SFRS1 interacting protein 1 | -0.00347214 |
| MTA1 | metastasis associated 1 | -0.00347127 |
| RNASET2 | ribonuclease T2 | -0.00346747 |
| BRD4 | bromodomain containing 4 | -0.00346672 |
| CYTIP | cytohesin 1 interacting protein | -0.00346214 |
| MAPK14 | mitogen-activated protein kinase 14 | -0.00346082 |
| STX4 | syntaxin 4 | -0.00345996 |
| SUMO3 | small ubiquitin-like modifier 3 | -0.00345841 |
| DPP8 | dipeptidyl-peptidase 8 | -0.00345589 |
| KAT2B | K(lysine) acetyltransferase 2B | -0.00345446 |
| HCP5 | HLA complex P5 (non-protein coding) | -0.00345025 |
| MUC4 | mucin 4, cell surface associated | -0.00344229 |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 | -0.00343733 |
| WFDC2 | WAP four-disulfide core domain 2 | -0.00343572 |
| SORBS3 | sorbin and SH3 domain containing 3 | -0.00341907 |
| ZNF204P | zinc finger protein 204, pseudogene | -0.00341776 |
| ZNF266 | zinc finger protein 266 | -0.00341576 |
| TFF3 | trefoil factor 3 (intestinal) | -0.00341424 |
| COL6A1 | collagen, type VI, alpha 1 | -0.00341295 |
| PRPF8 | pre-mRNA processing factor 8 | -0.00341182 |
| ZNF274 | zinc finger protein 274 | -0.00340393 |
| TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) | -0.00340229 |
| ANKRD11 | ankyrin repeat domain 11 | -0.00339015 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | -0.00338262 |
| FRYL | FRY-like | -0.00338222 |
| HLA-G | major histocompatibility complex, class I, G | -0.00336693 |
| CORO1A | coronin, actin binding protein, 1A | -0.00332889 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | -0.00332364 |
| MUC16 | mucin 16, cell surface associated | -0.00332273 |
| CA2 | carbonic anhydrase II | -0.00332039 |
| SYT17 | synaptotagmin XVII | -0.00331772 |
| KANK2 | KN motif and ankyrin repeat domains 2 | -0.00331644 |
| C1QA | complement component 1, q subcomponent, A chain | -0.00331169 |
| PRPF3 | pre-mRNA processing factor 3 | -0.00330804 |
| NARF | nuclear prelamin A recognition factor | -0.00330506 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 | -0.00329857 |
| ATP1A1 | ATPase, Na+/K+ transporting, alpha 1 polypeptide | -0.00329045 |
| MNDA | myeloid cell nuclear differentiation antigen | -0.00328722 |
| BAX | BCL2-associated X protein | -0.00328119 |
| VLDLR | very low density lipoprotein receptor | -0.00328067 |
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog | -0.0032801 |
| RHOA | ras homolog family member A | -0.00327894 |
| CEP68 | centrosomal protein 68kDa | -0.00327836 |
| MYH10 | myosin, heavy chain 10, non-muscle | -0.0032726 |
| OPN3 | opsin 3 | -0.0032713 |
| CDA | cytidine deaminase | -0.00326823 |
| SRSF4 | serine/arginine-rich splicing factor 4 | -0.0032678 |
| CDC5L | cell division cycle 5-like | -0.00325672 |
| DEK | DEK proto-oncogene | -0.00325565 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.00324873 |
| C2 | complement component 2 | -0.00324794 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.00323138 |
| CLEC4A | C-type lectin domain family 4, member A | -0.00323065 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial | -0.00322894 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.00322655 |
| TTTY15 | testis-specific transcript, Y-linked 15 (non-protein coding) | -0.0032265 |
