PPBP Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)|The protein encoded by this gene is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells. The protein also is an antimicrobial protein with bactericidal and antifungal activity. [provided by RefSeq, Nov 2014] (NCBI Entrez Gene Database, 5473)
External Link http://www.ncbi.nlm.nih.gov/gene/5473
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Genes

149 interacting proteins for PPBP from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ADRA1B adrenoceptor alpha 1B
AGA aspartylglucosaminidase
AHSG alpha-2-HS-glycoprotein
ALB albumin
AMPD3 adenosine monophosphate deaminase 3
AP1M1 adaptor-related protein complex 1, mu 1 subunit
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit
APOA1 apolipoprotein A-I
APOA2 apolipoprotein A-II
APOA4 apolipoprotein A-IV
APOC1 apolipoprotein C-I
APOC2 apolipoprotein C-II
APOC3 apolipoprotein C-III
APOE apolipoprotein E
ATM ATM serine/threonine kinase
C4A complement component 4A (Rodgers blood group)
CABLES1 Cdk5 and Abl enzyme substrate 1
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CAMTA1 calmodulin binding transcription activator 1
CDC45 cell division cycle 45
CDCP1 CUB domain containing protein 1
CELF1 CUGBP, Elav-like family member 1
CEP44 centrosomal protein 44kDa
CFB complement factor B
CFD complement factor D (adipsin)
CFH complement factor H
CHKB choline kinase beta
CLCA2 chloride channel accessory 2
CMTM6 CKLF-like MARVEL transmembrane domain containing 6
CNOT1 CCR4-NOT transcription complex, subunit 1
COPG1 coatomer protein complex, subunit gamma 1
COPS7A COP9 signalosome subunit 7A
COX17 COX17 cytochrome c oxidase copper chaperone
CRB1 crumbs family member 1, photoreceptor morphogenesis associated
CROT carnitine O-octanoyltransferase
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CST3 cystatin C
CTAGE5 CTAGE family, member 5
CTSG cathepsin G
CXCR1 chemokine (C-X-C motif) receptor 1
CXCR2 chemokine (C-X-C motif) receptor 2
DCD dermcidin
DDB1 damage-specific DNA binding protein 1, 127kDa
DERL1 derlin 1
DGKG diacylglycerol kinase, gamma 90kDa
DICER1 dicer 1, ribonuclease type III
DMD dystrophin
DMWD dystrophia myotonica, WD repeat containing
EFNA1 ephrin-A1
ETF1 eukaryotic translation termination factor 1
EXOC6 exocyst complex component 6
F2 coagulation factor II (thrombin)
F7 coagulation factor VII (serum prothrombin conversion accelerator)
FAM71E2 family with sequence similarity 71, member E2
FGA fibrinogen alpha chain
FN1 fibronectin 1
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GCN1L1 GCN1 general control of amino-acid synthesis 1-like 1 (yeast)
GFAP glial fibrillary acidic protein
GJC2 gap junction protein, gamma 2, 47kDa
GRAP2 GRB2-related adaptor protein 2
GSN gelsolin
HBA2 hemoglobin, alpha 2
HP haptoglobin
HPX hemopexin
IGDCC4 immunoglobulin superfamily, DCC subclass, member 4
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IGKC immunoglobulin kappa constant
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGB5 integrin, beta 5
ITIH1 inter-alpha-trypsin inhibitor heavy chain 1
JARID2 jumonji, AT rich interactive domain 2
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KIAA0232 KIAA0232
KIAA1551 KIAA1551
KLK3 kallikrein-related peptidase 3
KRT1 keratin 1, type II
KRT10 keratin 10, type I
KRT13 keratin 13, type I
KRT14 keratin 14, type I
KRT16 keratin 16, type I
KRT5 keratin 5, type II
KRT6A keratin 6A, type II
KRT6B keratin 6B, type II
KRT9 keratin 9, type I
LAT linker for activation of T cells
LDB3 LIM domain binding 3
MAPK6 mitogen-activated protein kinase 6
MOB3B MOB kinase activator 3B
MYL4 myosin, light chain 4, alkali; atrial, embryonic
MYLK3 myosin light chain kinase 3
NCOA3 nuclear receptor coactivator 3
NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa
NLRC4 NLR family, CARD domain containing 4
NPHS1 nephrosis 1, congenital, Finnish type (nephrin)
NR4A1 nuclear receptor subfamily 4, group A, member 1
OBSL1 obscurin-like 1
OR2T6 olfactory receptor, family 2, subfamily T, member 6
OR3A2 olfactory receptor, family 3, subfamily A, member 2
OR8D2 olfactory receptor, family 8, subfamily D, member 2 (gene/pseudogene)
PALB2 partner and localizer of BRCA2
PCDH1 protocadherin 1
PCED1B PC-esterase domain containing 1B
PDE4B phosphodiesterase 4B, cAMP-specific
PDZRN4 PDZ domain containing ring finger 4
PEG3 paternally expressed 3
PF4V1 platelet factor 4 variant 1
PHC3 polyhomeotic homolog 3 (Drosophila)
PLA2G4F phospholipase A2, group IVF
PLAG1 pleiomorphic adenoma gene 1
PLEKHJ1 pleckstrin homology domain containing, family J member 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PRSS3 protease, serine, 3
PRSS3P2 protease, serine, 3 pseudogene 2
QRSL1 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1
QTRTD1 queuine tRNA-ribosyltransferase domain containing 1
RAB10 RAB10, member RAS oncogene family
RANBP2 RAN binding protein 2
RANBP3 RAN binding protein 3
RLF rearranged L-myc fusion
RPS27 ribosomal protein S27
RYR2 ryanodine receptor 2 (cardiac)
SACS sacsin molecular chaperone
SCAF1 SR-related CTD-associated factor 1
SCFD1 sec1 family domain containing 1
SCN5A sodium channel, voltage gated, type V alpha subunit
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SETX senataxin
SGOL2 shugoshin-like 2 (S. pombe)
SH3BP5 SH3-domain binding protein 5 (BTK-associated)
SLA2 Src-like-adaptor 2
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SORBS3 sorbin and SH3 domain containing 3
SPAST spastin
SPATA31A7 SPATA31 subfamily A, member 7
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)
STRN4 striatin, calmodulin binding protein 4
THRAP3 thyroid hormone receptor associated protein 3
TIAM1 T-cell lymphoma invasion and metastasis 1
TLN2 talin 2
TRAPPC11 trafficking protein particle complex 11
TSC22D1 TSC22 domain family, member 1
TTN titin
TTPAL tocopherol (alpha) transfer protein-like
TTR transthyretin
ZNF232 zinc finger protein 232
ZNF292 zinc finger protein 292