| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | peptidylprolyl isomerase B (cyclophilin B)|The protein encoded by this gene is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta. [provided by RefSeq, Oct 2009] (NCBI Entrez Gene Database, 5479) |
| External Link | https://ncbi.nlm.nih.gov/gene/5479 |
| Similar Terms | |
| Downloads & Tools |
500 genes differentially expressed following the PPIB gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PCNA | proliferating cell nuclear antigen | 0.010782 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0103536 |
| NUP85 | nucleoporin 85kDa | 0.00876782 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 0.00841978 |
| YME1L1 | YME1-like 1 ATPase | 0.00838944 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | 0.00828768 |
| BEX1 | brain expressed, X-linked 1 | 0.0082343 |
| SRSF1 | serine/arginine-rich splicing factor 1 | 0.00774996 |
| EXOC5 | exocyst complex component 5 | 0.00763886 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | 0.00747834 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.00739119 |
| MPO | myeloperoxidase | 0.00710177 |
| LMAN1 | lectin, mannose-binding, 1 | 0.00696716 |
| SCAMP1 | secretory carrier membrane protein 1 | 0.00688801 |
| TFDP1 | transcription factor Dp-1 | 0.0068539 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.00675319 |
| FBXO11 | F-box protein 11 | 0.00666411 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.00647549 |
| PIGP | phosphatidylinositol glycan anchor biosynthesis, class P | 0.00646302 |
| IVNS1ABP | influenza virus NS1A binding protein | 0.00645663 |
| CRABP2 | cellular retinoic acid binding protein 2 | 0.0064251 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 | 0.00639084 |
| SEPP1 | selenoprotein P, plasma, 1 | 0.0063782 |
| PCP4 | Purkinje cell protein 4 | 0.00635686 |
| GTF2I | general transcription factor IIi | 0.00628771 |
| PTCH1 | patched 1 | 0.0062291 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 0.00622596 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.00622251 |
| PNN | pinin, desmosome associated protein | 0.00605913 |
| WT1 | Wilms tumor 1 | 0.00604126 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.00603568 |
| CTSC | cathepsin C | 0.00602937 |
| ATP1A1 | ATPase, Na+/K+ transporting, alpha 1 polypeptide | 0.00600846 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 | 0.00599445 |
| RGCC | regulator of cell cycle | 0.00596447 |
| PCLAF | PCNA clamp associated factor | 0.00596441 |
| ANXA3 | annexin A3 | 0.00593145 |
| TYMS | thymidylate synthetase | 0.00592863 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.00591146 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | 0.00588497 |
| H2AZ1 | H2A.Z variant histone 1 | 0.00588165 |
| ME2 | malic enzyme 2, NAD(+)-dependent, mitochondrial | 0.00587411 |
| GSE1 | Gse1 coiled-coil protein | 0.00587285 |
| MARCKSL1 | MARCKS-like 1 | 0.00585219 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.005821 |
| PSMA3 | proteasome (prosome, macropain) subunit, alpha type, 3 | 0.00578169 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | 0.00571817 |
| TMEM230 | transmembrane protein 230 | 0.00568479 |
| GPHN | gephyrin | 0.00565386 |
| CCNB1 | cyclin B1 | 0.00558574 |
| SMAD5 | SMAD family member 5 | 0.00558506 |
| CHIT1 | chitinase 1 (chitotriosidase) | 0.00556831 |
| CDKN3 | cyclin-dependent kinase inhibitor 3 | 0.00556177 |
| ZBTB1 | zinc finger and BTB domain containing 1 | 0.00550997 |
| LTA4H | leukotriene A4 hydrolase | 0.00550789 |
| E2F2 | E2F transcription factor 2 | 0.00548643 |
| SUMO3 | small ubiquitin-like modifier 3 | 0.00548597 |
| GDI2 | GDP dissociation inhibitor 2 | 0.00547812 |
| WASF1 | WAS protein family, member 1 | 0.0054503 |
| INHBB | inhibin, beta B | 0.0054493 |
| ELAVL1 | ELAV like RNA binding protein 1 | 0.00544332 |
| IDE | insulin-degrading enzyme | 0.00541384 |
| CAPRIN1 | cell cycle associated protein 1 | 0.00539653 |
| CCL14 | chemokine (C-C motif) ligand 14 | 0.00539159 |
| SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 | 0.00538991 |
| ANXA6 | annexin A6 | 0.00538687 |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 | 0.00538132 |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit | 0.00537598 |
| NUDT21 | nudix (nucleoside diphosphate linked moiety X)-type motif 21 | 0.00535403 |
| NCK1 | NCK adaptor protein 1 | 0.00534888 |
| PRNP | prion protein | 0.00532471 |
| ATP5F1C | ATP synthase F1 subunit gamma | 0.00529539 |
| ZMYND11 | zinc finger, MYND-type containing 11 | 0.00528552 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.00527387 |
| CLC | Charcot-Leyden crystal galectin | 0.00523979 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.00522421 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | 0.00522064 |
| TESC | tescalcin | 0.0051884 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.00515209 |
| SRSF7 | serine/arginine-rich splicing factor 7 | 0.00510322 |
| KIF14 | kinesin family member 14 | 0.00509542 |
| CTSV | cathepsin V | 0.00508731 |
| SPTSSA | serine palmitoyltransferase, small subunit A | 0.0050678 |
| ETV1 | ets variant 1 | 0.00503508 |
| ARG1 | arginase 1 | 0.00503057 |
| RAP2A | RAP2A, member of RAS oncogene family | 0.00498307 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.00498132 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | 0.00497734 |
| SFTPA2 | surfactant protein A2 | 0.00497587 |
| UBE2G2 | ubiquitin-conjugating enzyme E2G 2 | 0.00495287 |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 | 0.00494599 |
| ECHDC2 | enoyl CoA hydratase domain containing 2 | 0.0049356 |
| TSPAN5 | tetraspanin 5 | 0.00490652 |
| STON1 | stonin 1 | 0.00488121 |
| ELOVL4 | ELOVL fatty acid elongase 4 | 0.00486917 |
| BNC2 | basonuclin 2 | 0.00485054 |
| ACAA2 | acetyl-CoA acyltransferase 2 | 0.00482471 |
| SLC39A6 | solute carrier family 39 (zinc transporter), member 6 | 0.00481637 |
| WAC | WW domain containing adaptor with coiled-coil | 0.00479499 |
| ELK4 | ELK4, ETS-domain protein (SRF accessory protein 1) | 0.00478088 |
| HMGB3 | high mobility group box 3 | 0.00477161 |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) | 0.00476312 |
| CGGBP1 | CGG triplet repeat binding protein 1 | 0.00474765 |
| RGS5 | regulator of G-protein signaling 5 | 0.00472921 |
| TWSG1 | twisted gastrulation BMP signaling modulator 1 | 0.00472362 |
| U2AF1 | U2 small nuclear RNA auxiliary factor 1 | 0.00471426 |
| PURA | purine-rich element binding protein A | 0.00470432 |
| COLEC12 | collectin sub-family member 12 | 0.00470181 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | 0.00470069 |
| MTHFD1 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase | 0.00469661 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | 0.00468636 |
| CEACAM8 | carcinoembryonic antigen-related cell adhesion molecule 8 | 0.00468414 |
| CST1 | cystatin SN | 0.00465675 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.00465397 |
| DHFR | dihydrofolate reductase | 0.00464494 |
| PLS3 | plastin 3 | 0.00463214 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | 0.00461584 |
| SETD5 | SET domain containing 5 | 0.00459341 |
| USP34 | ubiquitin specific peptidase 34 | 0.00458125 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | 0.00458037 |
| HNRNPF | heterogeneous nuclear ribonucleoprotein F | 0.00457836 |
| MECOM | MDS1 and EVI1 complex locus | 0.00457399 |
| PCGF2 | polycomb group ring finger 2 | 0.00456747 |
| XPO7 | exportin 7 | 0.0045637 |
| SPART | spartin | 0.0045607 |
| RCHY1 | ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase | 0.00455796 |
| CTSG | cathepsin G | 0.00452356 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.00451228 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | 0.00450915 |
| MMP12 | matrix metallopeptidase 12 | 0.00449901 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0044649 |
| VANGL1 | VANGL planar cell polarity protein 1 | 0.00446199 |
| RBL2 | retinoblastoma-like 2 | 0.00446164 |
| UTRN | utrophin | 0.00446122 |
| RAD51C | RAD51 paralog C | 0.00445575 |
| LONP2 | lon peptidase 2, peroxisomal | 0.00443748 |
| EXPH5 | exophilin 5 | 0.00442168 |
| ACAT2 | acetyl-CoA acetyltransferase 2 | 0.00442019 |
| SGPP1 | sphingosine-1-phosphate phosphatase 1 | 0.0044051 |
| TPBG | trophoblast glycoprotein | 0.00440489 |
| CANX | calnexin | 0.00440346 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | 0.00439359 |
| ATP5PD | ATP synthase peripheral stalk subunit d | 0.00438347 |
| NNT | nicotinamide nucleotide transhydrogenase | 0.00437894 |
| PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase | 0.00437685 |
| UBE2S | ubiquitin-conjugating enzyme E2S | 0.00436746 |
| SRSF10 | serine/arginine-rich splicing factor 10 | 0.00436577 |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) | 0.00436305 |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 | 0.00436087 |
| ZNF43 | zinc finger protein 43 | 0.0043507 |
| SIAH2 | siah E3 ubiquitin protein ligase 2 | 0.00433223 |
| EPAS1 | endothelial PAS domain protein 1 | 0.00432983 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | 0.0043209 |
| STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase | 0.0043147 |
| ABHD17B | abhydrolase domain containing 17B | 0.00430563 |
| PROSER1 | proline and serine rich 1 | 0.0042985 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | 0.00429559 |
| EPHA4 | EPH receptor A4 | 0.0042849 |
| ENSA | endosulfine alpha | 0.00428268 |
| HMGB2 | high mobility group box 2 | 0.0042694 |
| EAPP | E2F-associated phosphoprotein | 0.0042506 |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa | 0.0042497 |
| ZNF586 | zinc finger protein 586 | 0.00424794 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | 0.00422989 |
| CRABP1 | cellular retinoic acid binding protein 1 | 0.00422624 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | 0.00422411 |
| HSPA14 | heat shock 70kDa protein 14 | 0.00420942 |
| UBL3 | ubiquitin-like 3 | 0.00420207 |
| HMGN1 | high mobility group nucleosome binding domain 1 | 0.00418907 |
| MPPED2 | metallophosphoesterase domain containing 2 | 0.00418839 |
| MRPL42 | mitochondrial ribosomal protein L42 | 0.00417582 |
| MPP5 | membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) | 0.00416472 |
| SFTPB | surfactant protein B | 0.00415609 |
| ITGA6 | integrin, alpha 6 | 0.00415145 |
| RBBP4 | retinoblastoma binding protein 4 | 0.00414935 |
| PAXBP1 | PAX3 and PAX7 binding protein 1 | 0.00414715 |
| NVL | nuclear VCP-like | 0.00414584 |
| NBPF10 | neuroblastoma breakpoint family, member 10 | 0.00413312 |
| TUBB2A | tubulin, beta 2A class IIa | 0.00413193 |
| CLEC11A | C-type lectin domain family 11, member A | 0.00413124 |
| TLE2 | transducin-like enhancer of split 2 | 0.00411972 |
| RPRD1A | regulation of nuclear pre-mRNA domain containing 1A | 0.00411697 |
| HAL | histidine ammonia-lyase | 0.00410717 |
| SNX5 | sorting nexin 5 | 0.00410464 |
| PPP4R3A | protein phosphatase 4 regulatory subunit 3A | 0.00410149 |
| FBXO5 | F-box protein 5 | 0.00410073 |
| C7 | complement component 7 | 0.00409961 |
| NMD3 | NMD3 ribosome export adaptor | 0.00408026 |
| CMTM6 | CKLF-like MARVEL transmembrane domain containing 6 | 0.00407874 |
| EPCAM | epithelial cell adhesion molecule | 0.00405872 |
| MMP9 | matrix metallopeptidase 9 | 0.00404328 |
| ZBED4 | zinc finger, BED-type containing 4 | 0.00403976 |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa | 0.00403248 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | 0.0040255 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | 0.00401437 |
| SEPHS1 | selenophosphate synthetase 1 | 0.00401017 |
| HMGB1 | high mobility group box 1 | 0.00400466 |
| ESD | esterase D | 0.00400166 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.00399453 |
| ENDOD1 | endonuclease domain containing 1 | 0.00399409 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.00399144 |
| PTTG1 | pituitary tumor-transforming 1 | 0.00398283 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.00398119 |
| PUM2 | pumilio RNA-binding family member 2 | 0.00398102 |
| MAN1A2 | mannosidase, alpha, class 1A, member 2 | 0.00394851 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit | 0.00394633 |
| CD164 | CD164 molecule, sialomucin | 0.00394367 |
| SPIN1 | spindlin 1 | 0.00394319 |
| MCM3AP | minichromosome maintenance complex component 3 associated protein | 0.00393767 |
| ADORA2B | adenosine A2b receptor | 0.00393178 |
| DUT | deoxyuridine triphosphatase | 0.0039206 |
| METTL3 | methyltransferase like 3 | 0.00390846 |
| DMAC2L | distal membrane arm assembly component 2 like | 0.00390809 |
| RORA | RAR-related orphan receptor A | 0.00390485 |
| PER1 | period circadian clock 1 | 0.0039043 |
| DEFA4 | defensin, alpha 4, corticostatin | 0.00389571 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric | 0.00389498 |
| NKTR | natural killer cell triggering receptor | 0.00388377 |
| RAB23 | RAB23, member RAS oncogene family | 0.00386412 |
| BPI | bactericidal/permeability-increasing protein | 0.00382207 |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 | 0.00382147 |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) | 0.00382083 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.00381457 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | 0.00379024 |
| IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 | 0.00378908 |
| CCNL2 | cyclin L2 | 0.00377511 |
| PILRB | paired immunoglobin-like type 2 receptor beta | 0.00376938 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 0.00376926 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.00376381 |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) | 0.00376036 |
| ALDH6A1 | aldehyde dehydrogenase 6 family, member A1 | 0.00375023 |
| GCH1 | GTP cyclohydrolase 1 | 0.00374781 |
| LCE2B | late cornified envelope 2B | 0.00374587 |
| CAVIN2 | caveolae associated protein 2 | 0.00373862 |
| PRPF18 | pre-mRNA processing factor 18 | 0.00373467 |
| DAZAP2 | DAZ associated protein 2 | 0.00373232 |
| AOC1 | amine oxidase, copper containing 1 | 0.0037311 |
| GLRX5 | glutaredoxin 5 | 0.0037176 |
| PFDN4 | prefoldin subunit 4 | 0.0037173 |
| DENND1B | DENN/MADD domain containing 1B | 0.00371618 |
| RPL36AL | ribosomal protein L36a-like | 0.00371609 |
| NME4 | NME/NM23 nucleoside diphosphate kinase 4 | 0.00371342 |
| LDB2 | LIM domain binding 2 | 0.00371015 |
| ARL4A | ADP-ribosylation factor-like 4A | 0.00370838 |
| PAQR6 | progestin and adipoQ receptor family member VI | 0.00369637 |
| ASXL2 | additional sex combs like transcriptional regulator 2 | 0.00369526 |
| LXN | latexin | 0.00369383 |
| TGIF2 | TGFB-induced factor homeobox 2 | 0.00368217 |
| SCAF4 | SR-related CTD-associated factor 4 | 0.00367957 |
| KLHL23 | kelch-like family member 23 | 0.00366498 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AQP3 | aquaporin 3 (Gill blood group) | -0.0131813 |
| KRT14 | keratin 14, type I | -0.0122718 |
| MAMLD1 | mastermind-like domain containing 1 | -0.0121996 |
| COQ8A | coenzyme Q8A | -0.0121209 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | -0.0120758 |
| C3 | complement component 3 | -0.0116988 |
| JCHAIN | joining chain of multimeric IgA and IgM | -0.0107925 |
| CFB | complement factor B | -0.0106577 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | -0.0102728 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | -0.0100077 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | -0.00997454 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | -0.00993945 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.00958462 |
| IL1B | interleukin 1, beta | -0.00946402 |
| PROM1 | prominin 1 | -0.00945195 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.00926287 |
| CLU | clusterin | -0.00903617 |
| LCN2 | lipocalin 2 | -0.00902097 |
| MMP7 | matrix metallopeptidase 7 | -0.0088568 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | -0.0087905 |
| ELN | elastin | -0.00866896 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.00861874 |
| APOD | apolipoprotein D | -0.00860335 |
| KRT7 | keratin 7, type II | -0.00848138 |
| ALOX5 | arachidonate 5-lipoxygenase | -0.00815451 |
| DSP | desmoplakin | -0.00815313 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0081513 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0081061 |
| C1S | complement component 1, s subcomponent | -0.00807568 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.00801347 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | -0.00793086 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.00782572 |
| NRCAM | neuronal cell adhesion molecule | -0.0077495 |
| SLPI | secretory leukocyte peptidase inhibitor | -0.00768806 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0076862 |
| KRT19 | keratin 19, type I | -0.00768419 |
| BICC1 | BicC family RNA binding protein 1 | -0.00766864 |
| MYBPC1 | myosin binding protein C, slow type | -0.00764973 |
| STAP2 | signal transducing adaptor family member 2 | -0.00758955 |
| PTGES | prostaglandin E synthase | -0.00758276 |
| BHLHE41 | basic helix-loop-helix family, member e41 | -0.00749632 |
| PERP | PERP, TP53 apoptosis effector | -0.00744936 |
| PDE4DIP | phosphodiesterase 4D interacting protein | -0.00739599 |
| SYNM | synemin, intermediate filament protein | -0.00735672 |
| C1R | complement component 1, r subcomponent | -0.00735602 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | -0.00734836 |
| CSTA | cystatin A (stefin A) | -0.00731775 |
| IGFBP6 | insulin-like growth factor binding protein 6 | -0.0071969 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.00719358 |
| S100A8 | S100 calcium binding protein A8 | -0.0071883 |
| PIP | prolactin-induced protein | -0.00718398 |
| ECM1 | extracellular matrix protein 1 | -0.00712602 |
| POLR2D | polymerase (RNA) II (DNA directed) polypeptide D | -0.00712005 |
| NKX3-1 | NK3 homeobox 1 | -0.00711998 |
| MB | myoglobin | -0.00711113 |
| ELK3 | ELK3, ETS-domain protein (SRF accessory protein 2) | -0.00702931 |
| COL14A1 | collagen, type XIV, alpha 1 | -0.0070102 |
| COX7A1 | cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) | -0.00698066 |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) | -0.00695132 |
| CRYAB | crystallin, alpha B | -0.00688036 |
| LUM | lumican | -0.00675378 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.00674817 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.00659496 |
| PENK | proenkephalin | -0.00659452 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.00659405 |
| KRT17 | keratin 17, type I | -0.00658408 |
| FRZB | frizzled-related protein | -0.00656035 |
| LPAR6 | lysophosphatidic acid receptor 6 | -0.00655623 |
| IL6 | interleukin 6 | -0.00655019 |
| EIF5A | eukaryotic translation initiation factor 5A | -0.00654937 |
| RTN1 | reticulon 1 | -0.00652747 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.00650739 |
| TGFA | transforming growth factor, alpha | -0.00649109 |
| SLN | sarcolipin | -0.00647434 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.00645675 |
| AXL | AXL receptor tyrosine kinase | -0.00645249 |
| NIBAN1 | niban apoptosis regulator 1 | -0.00639239 |
| CKM | creatine kinase, muscle | -0.00638869 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.00637918 |
| IL1RN | interleukin 1 receptor antagonist | -0.0063605 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.00631963 |
| MT1F | metallothionein 1F | -0.00629899 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.00628927 |
| SDC1 | syndecan 1 | -0.00626228 |
| MYL1 | myosin, light chain 1, alkali; skeletal, fast | -0.00622544 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | -0.00621327 |
| MT1M | metallothionein 1M | -0.00620928 |
| ITM2C | integral membrane protein 2C | -0.0062018 |
| FN1 | fibronectin 1 | -0.00619605 |
| DUSP5 | dual specificity phosphatase 5 | -0.00615984 |
| MMP3 | matrix metallopeptidase 3 | -0.00614948 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.00614172 |
| TPPP3 | tubulin polymerization-promoting protein family member 3 | -0.00614039 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | -0.00613972 |
| ANPEP | alanyl (membrane) aminopeptidase | -0.00613389 |
| S100A9 | S100 calcium binding protein A9 | -0.00610001 |
| SCRG1 | stimulator of chondrogenesis 1 | -0.00608933 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | -0.00606338 |
| FABP7 | fatty acid binding protein 7, brain | -0.00605132 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.00602485 |
| FGFR3 | fibroblast growth factor receptor 3 | -0.00602445 |
| TPD52L1 | tumor protein D52-like 1 | -0.00600163 |
| IL1A | interleukin 1, alpha | -0.00597375 |
| RAB29 | RAB29, member RAS oncogene family | -0.00589588 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | -0.00586429 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | -0.00584993 |
| SSPN | sarcospan | -0.00584613 |
| MAGEB2 | melanoma antigen family B2 | -0.00581591 |
| EMP3 | epithelial membrane protein 3 | -0.00571628 |
| INHBA | inhibin, beta A | -0.00569554 |
| CFH | complement factor H | -0.00568834 |
| IL13RA2 | interleukin 13 receptor, alpha 2 | -0.00566653 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | -0.00566387 |
| CSRP2 | cysteine and glycine-rich protein 2 | -0.0056605 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | -0.005659 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | -0.00564259 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | -0.00563598 |
| NNMT | nicotinamide N-methyltransferase | -0.00560366 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | -0.00558367 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.00557646 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.00557083 |
| LYZ | lysozyme | -0.00555811 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.00555491 |
| RND3 | Rho family GTPase 3 | -0.00555059 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.00554677 |
| DCN | decorin | -0.00552656 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.00552385 |
| MT1X | metallothionein 1X | -0.00552356 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | -0.00551806 |
| TGM2 | transglutaminase 2 | -0.00551029 |
| S100A7 | S100 calcium binding protein A7 | -0.00550828 |
| FKBP11 | FK506 binding protein 11, 19 kDa | -0.00550683 |
| FST | follistatin | -0.00548035 |
| BIN1 | bridging integrator 1 | -0.00543348 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.00542834 |
| HIST1H2AC | histone cluster 1, H2ac | -0.0054255 |
| SNX10 | sorting nexin 10 | -0.00540617 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.0053986 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.00537141 |
| GPRC5B | G protein-coupled receptor, class C, group 5, member B | -0.0053372 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.00533483 |
| THBS1 | thrombospondin 1 | -0.00532912 |
| G0S2 | G0/G1 switch 2 | -0.00532817 |
| TBX3 | T-box 3 | -0.00531925 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | -0.00530636 |
| CRYM | crystallin, mu | -0.0053012 |
| SIRPA | signal-regulatory protein alpha | -0.00529706 |
| TAX1BP3 | Tax1 (human T-cell leukemia virus type I) binding protein 3 | -0.00529688 |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) | -0.00529687 |
| CYB5R2 | cytochrome b5 reductase 2 | -0.0052857 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | -0.00528221 |
| TPM2 | tropomyosin 2 (beta) | -0.00525942 |
| AK1 | adenylate kinase 1 | -0.00525745 |
| TRIM38 | tripartite motif containing 38 | -0.00523572 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | -0.0052308 |
| KRT5 | keratin 5, type II | -0.00522779 |
| RHOD | ras homolog family member D | -0.00522671 |
| RIPOR2 | RHO family interacting cell polarization regulator 2 | -0.00522564 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.00519915 |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 | -0.00519319 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | -0.00517321 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.00515727 |
| EPHA3 | EPH receptor A3 | -0.00515599 |
| ICAM2 | intercellular adhesion molecule 2 | -0.00515547 |
| ST18 | suppression of tumorigenicity 18, zinc finger | -0.00514401 |
| LIMK2 | LIM domain kinase 2 | -0.00512832 |
| MAGEA3 | melanoma antigen family A3 | -0.00512524 |
| WWC1 | WW and C2 domain containing 1 | -0.00510125 |
| GPX1 | glutathione peroxidase 1 | -0.00509372 |
| GMPR | guanosine monophosphate reductase | -0.00509187 |
| MAPK13 | mitogen-activated protein kinase 13 | -0.00507687 |
| MYL2 | myosin, light chain 2, regulatory, cardiac, slow | -0.0050645 |
| KLHL41 | kelch-like family member 41 | -0.00505762 |
| MXRA7 | matrix-remodelling associated 7 | -0.00503649 |
| ARHGEF40 | Rho guanine nucleotide exchange factor (GEF) 40 | -0.00503605 |
| SECTM1 | secreted and transmembrane 1 | -0.00503202 |
| LRRN3 | leucine rich repeat neuronal 3 | -0.00502683 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog | -0.00502202 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | -0.00501068 |
| VSNL1 | visinin-like 1 | -0.00498937 |
| ISLR | immunoglobulin superfamily containing leucine-rich repeat | -0.00498433 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 | -0.00497613 |
| TNNC2 | troponin C type 2 (fast) | -0.00497346 |
| HSPB7 | heat shock 27kDa protein family, member 7 (cardiovascular) | -0.00497004 |
| PI3 | peptidase inhibitor 3, skin-derived | -0.00496223 |
| LMCD1 | LIM and cysteine-rich domains 1 | -0.00495509 |
| ZNF365 | zinc finger protein 365 | -0.00494318 |
| RRAD | Ras-related associated with diabetes | -0.00493486 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.00493061 |
| FADS3 | fatty acid desaturase 3 | -0.00492458 |
| IL7R | interleukin 7 receptor | -0.00492227 |
| KANK1 | KN motif and ankyrin repeat domains 1 | -0.00492123 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 | -0.00491255 |
| ITGAV | integrin, alpha V | -0.00491004 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.00489629 |
| IL6R | interleukin 6 receptor | -0.00485971 |
| STAT4 | signal transducer and activator of transcription 4 | -0.00485447 |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | -0.00484366 |
| PAK6 | p21 protein (Cdc42/Rac)-activated kinase 6 | -0.00484116 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | -0.00483548 |
| HIST1H2BK | histone cluster 1, H2bk | -0.00482475 |
| COL15A1 | collagen, type XV, alpha 1 | -0.00481701 |
| TNNI2 | troponin I type 2 (skeletal, fast) | -0.00480824 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.00480342 |
| ENAH | enabled homolog (Drosophila) | -0.00478078 |
| GDF15 | growth differentiation factor 15 | -0.00477325 |
| KRT13 | keratin 13, type I | -0.0047242 |
| CHMP4A | charged multivesicular body protein 4A | -0.00470861 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.00468279 |
| DIPK1A | divergent protein kinase domain 1A | -0.0046798 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.00467674 |
| LACTB2 | lactamase, beta 2 | -0.00467518 |
| KLF2 | Kruppel-like factor 2 | -0.00467322 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | -0.00467242 |
| CDCP1 | CUB domain containing protein 1 | -0.00464923 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.00464188 |
| CD9 | CD9 molecule | -0.00462936 |
| MFAP3L | microfibrillar-associated protein 3-like | -0.00462936 |
| GPX2 | glutathione peroxidase 2 | -0.0046256 |
| ZNF185 | zinc finger protein 185 (LIM domain) | -0.00461799 |
| FABP6 | fatty acid binding protein 6, ileal | -0.00461682 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.00461211 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | -0.00460764 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 | -0.00459534 |
| PRUNE2 | prune homolog 2 (Drosophila) | -0.00459396 |
| MYLPF | myosin light chain, phosphorylatable, fast skeletal muscle | -0.00459369 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 | -0.00458588 |
| CH25H | cholesterol 25-hydroxylase | -0.00458454 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 | -0.00458275 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.00458143 |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous | -0.00457968 |
| ATP6V0E2 | ATPase, H+ transporting V0 subunit e2 | -0.00456998 |
| MN1 | meningioma (disrupted in balanced translocation) 1 | -0.00456916 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.00455011 |
| DEPTOR | DEP domain containing MTOR-interacting protein | -0.00454967 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 | -0.00454818 |
| MAOB | monoamine oxidase B | -0.00453905 |
| FBLN5 | fibulin 5 | -0.00453249 |
| CD38 | CD38 molecule | -0.00453229 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.00453229 |
| RAB8A | RAB8A, member RAS oncogene family | -0.00453038 |
| C10ORF10 | chromosome 10 open reading frame 10 | -0.00452838 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.00452369 |
| TUBA4A | tubulin, alpha 4a | -0.00451578 |
| GPC3 | glypican 3 | -0.00450529 |
| SELPLG | selectin P ligand | -0.00448474 |
| FUCA1 | fucosidase, alpha-L- 1, tissue | -0.00446848 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.00446626 |
| GLUD1 | glutamate dehydrogenase 1 | -0.00446002 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | -0.00445867 |
