PPIE Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description peptidylprolyl isomerase E (cyclophilin E)|The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein contains a highly conserved cyclophilin (CYP) domain as well as an RNA-binding domain. It was shown to possess PPIase and protein folding activities, and it also exhibits RNA-binding activity. Alternative splicing results in multiple transcript variants. A related pseudogene, which is also located on chromosome 1, has been identified. [provided by RefSeq, Aug 2010] (NCBI Entrez Gene Database, 10450)
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Genes

636 genes differentially expressed following the PPIE gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 2.35352
MORN2 MORN repeat containing 2 2.35352
GANC glucosidase, alpha; neutral C 2.35352
TSC22D4 TSC22 domain family, member 4 2.34401
ZNF785 zinc finger protein 785 2.34401
ZNF382 zinc finger protein 382 2.34401
LRFN1 leucine rich repeat and fibronectin type III domain containing 1 2.34401
KREMEN2 kringle containing transmembrane protein 2 2.34401
SLC6A16 solute carrier family 6, member 16 2.34401
CPA6 carboxypeptidase A6 2.34401
CCDC60 coiled-coil domain containing 60 2.34401
OMD osteomodulin 2.34401
PLCG1 phospholipase C, gamma 1 2.34401
RUMY4 RUMY family member 4 2.34401
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6 2.34401
C19ORF44 chromosome 19 open reading frame 44 2.34401
TFIP11 tuftelin interacting protein 11 2.34401
NCDN neurochondrin 2.34401
DPF3 D4, zinc and double PHD fingers, family 3 2.34401
CDK15 cyclin-dependent kinase 15 2.34401
FOXN3 forkhead box N3 2.34401
PARD6B par-6 family cell polarity regulator beta 2.34401
SNTG1 syntrophin, gamma 1 2.34401
ANKLE1 ankyrin repeat and LEM domain containing 1 2.34401
HPCA hippocalcin 2.34401
CCDC157 coiled-coil domain containing 157 2.34401
SPACA9 sperm acrosome associated 9 2.34401
ZNF468 zinc finger protein 468 2.31404
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A 2.31404
THAP4 THAP domain containing 4 2.31404
SYNJ1 synaptojanin 1 2.31404
ZNF653 zinc finger protein 653 2.31404
SSC4D scavenger receptor cysteine rich family, 4 domains 2.31404
OR2A42 olfactory receptor, family 2, subfamily A, member 42 2.28298
SYNPO2L synaptopodin 2-like 2.28298
EHD2 EH-domain containing 2 2.28298
ZNF668 zinc finger protein 668 2.28298
CASP7 caspase 7, apoptosis-related cysteine peptidase 2.28298
PPARG peroxisome proliferator-activated receptor gamma 2.28298
AKT1S1 AKT1 substrate 1 (proline-rich) 2.28298
RUNDC3B RUN domain containing 3B 2.28298
PNMA3 paraneoplastic Ma antigen 3 2.28298
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 2.28298
NECAB3 N-terminal EF-hand calcium binding protein 3 2.28298
L3HYPDH L-3-hydroxyproline dehydratase (trans-) 2.28298
TMEM25 transmembrane protein 25 2.28298
IZUMO3 IZUMO family member 3 2.28298
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 2.28298
PROKR1 prokineticin receptor 1 2.28298
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 2.28298
RP1L1 retinitis pigmentosa 1-like 1 2.28298
BTK Bruton agammaglobulinemia tyrosine kinase 2.28298
NXPH1 neurexophilin 1 2.28298
NPAP1 nuclear pore associated protein 1 2.28298
NPPC natriuretic peptide C 2.28298
TRIM17 tripartite motif containing 17 2.28298
ALG1L2 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase-like 2 2.28298
AIG1 androgen-induced 1 2.28298
RTN2 reticulon 2 2.28298
DENND6B DENN/MADD domain containing 6B 2.28298
TMEM79 transmembrane protein 79 2.28298
MGARP mitochondria-localized glutamic acid-rich protein 2.28298
WDR55 WD repeat domain 55 2.28298
PPP1R3D protein phosphatase 1, regulatory subunit 3D 2.28298
BIRC6 baculoviral IAP repeat containing 6 2.28298
ARHGEF19 Rho guanine nucleotide exchange factor (GEF) 19 2.28298
SERF1A small EDRK-rich factor 1A (telomeric) 2.28298
CYLD cylindromatosis (turban tumor syndrome) 2.28298
CD164L2 CD164 sialomucin-like 2 2.28298
RAB24 RAB24, member RAS oncogene family 2.28298
ERMARD ER membrane-associated RNA degradation 2.28298
MTURN maturin, neural progenitor differentiation regulator homolog (Xenopus) 2.28298
CAPS calcyphosine 2.28298
PRDM11 PR domain containing 11 2.28298
IL2RB interleukin 2 receptor, beta 2.28298
ZNF157 zinc finger protein 157 2.28298
TMEM200C transmembrane protein 200C 2.28298
COQ7 coenzyme Q7 homolog, ubiquinone (yeast) 2.28298
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2 2.28298
ZNF180 zinc finger protein 180 2.28298
CRYL1 crystallin, lambda 1 2.28298
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12 2.28298
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2 2.28298
TMEM175 transmembrane protein 175 2.28298
TPST1 tyrosylprotein sulfotransferase 1 2.28298
CCDC61 coiled-coil domain containing 61 2.28298
ZNF41 zinc finger protein 41 2.28298
CCDC68 coiled-coil domain containing 68 2.28298
FDXR ferredoxin reductase 2.28298
MRPL53 mitochondrial ribosomal protein L53 2.28298
M1AP meiosis 1 associated protein 2.28298
CMYA5 cardiomyopathy associated 5 2.28298
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4 2.28298
TOB1 transducer of ERBB2, 1 2.28298
MORN3 MORN repeat containing 3 2.28298
MED13 mediator complex subunit 13 2.28298
SPOCD1 SPOC domain containing 1 2.28298
ASB18 ankyrin repeat and SOCS box containing 18 2.28298
MANSC4 MANSC domain containing 4 2.28298
SMIM10L2B small integral membrane protein 10 like 2B 2.28298
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit 2.28298
PPP1R11 protein phosphatase 1, regulatory (inhibitor) subunit 11 2.28298
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3 2.28298
XKRX XK, Kell blood group complex subunit-related, X-linked 2.28298
RPS9 ribosomal protein S9 2.28298
TBC1D30 TBC1 domain family, member 30 2.28298
FIMP1 fertilization-influencing membrane protein 1 2.28298
SCN4B sodium channel, voltage gated, type IV beta subunit 2.28298
EMID1 EMI domain containing 1 2.28298
TNNC2 troponin C type 2 (fast) 2.28298
CLDN19 claudin 19 2.28298
TSPAN7 tetraspanin 7 2.28298
ST6GALNAC6 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 2.28298
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive) 2.28298
PLB1 phospholipase B1 2.28298
CASKIN2 CASK interacting protein 2 2.28298
SAMD11 sterile alpha motif domain containing 11 2.28298
TEX9 testis expressed 9 2.28298
UGT2A1 UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus 2.28298
CNTN3 contactin 3 (plasmacytoma associated) 2.28298
UNC80 unc-80 homolog (C. elegans) 2.28298
STAC2 SH3 and cysteine rich domain 2 2.28298
FKBP6 FK506 binding protein 6, 36kDa 2.28298
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome 2.28298
JHY junctional cadherin complex regulator 2.28298
TMEM269 transmembrane protein 269 2.28298
SNORC secondary ossification center associated regulator of chondrocyte maturation 2.28298
PABIR3 PABIR family member 3 2.28298
ZNG1F Zn regulated GTPase metalloprotein activator 1F 2.28298
C10ORF143 chromosome 10 open reading frame 143 2.28298
LINC02560 long intergenic non-protein coding RNA 2560 2.28298
IL6ST-DT IL6ST divergent transcript 2.28298
ATP5MGL ATP synthase membrane subunit g like 2.28298
PHETA2 PH domain containing endocytic trafficking adaptor 2 2.28298
TRMT9B tRNA methyltransferase 9B (putative) 2.28298
HAO2 hydroxyacid oxidase 2 (long chain) 2.28298
FAM234B family with sequence similarity 234 member B 2.28298
MISP3 MISP family member 3 2.28298
CCN3 cellular communication network factor 3 2.28298
STUM stum, mechanosensory transduction mediator homolog 2.28298
H2BC21 H2B clustered histone 21 2.28298
GARIN5A golgi associated RAB2 interactor 5A 2.28298
KICS2 KICSTOR subunit 2 2.28298
SLC68A1 solute carrier family 68 member 1 2.28298
CYP4V2 cytochrome P450, family 4, subfamily V, polypeptide 2 2.28298
ZNF747 zinc finger protein 747 2.28298
MOSPD3 motile sperm domain containing 3 2.28298
ZNF432 zinc finger protein 432 2.28298
RAB43 RAB43, member RAS oncogene family 2.28298
PCDHA1 protocadherin alpha 1 2.28298
SAXO1 stabilizer of axonemal microtubules 1 2.28298
TMEM9B TMEM9 domain family, member B 2.28298
CCDC13 coiled-coil domain containing 13 2.28298
IRF1 interferon regulatory factor 1 2.28298
ERAS ES cell expressed Ras 2.28298
SPDYE6 speedy/RINGO cell cycle regulator family member E6 2.28298
PPP1R15A protein phosphatase 1, regulatory subunit 15A 2.28298
INHBE inhibin, beta E 2.28298
BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa 2.28298
FA2H fatty acid 2-hydroxylase 2.28298
HRH4 histamine receptor H4 2.28298
LHCGR luteinizing hormone/choriogonadotropin receptor 2.28298
ZNF583 zinc finger protein 583 2.28298
SF3B3 splicing factor 3b, subunit 3, 130kDa 2.28298
TCP11L2 t-complex 11, testis-specific-like 2 2.28298
SNX21 sorting nexin family member 21 2.28298
PANX2 pannexin 2 2.28298
SGSM2 small G protein signaling modulator 2 2.28298
BMI1 BMI1 proto-oncogene, polycomb ring finger 2.28298
MOB3A MOB kinase activator 3A 2.28298
OSCP1 organic solute carrier partner 1 2.28298
CNOT3 CCR4-NOT transcription complex, subunit 3 2.28298
CCDC120 coiled-coil domain containing 120 2.28298
STK24 serine/threonine kinase 24 2.28298
FURIN furin (paired basic amino acid cleaving enzyme) 2.28298
ZNF639 zinc finger protein 639 2.28298
ACP5 acid phosphatase 5, tartrate resistant 2.28298
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2 2.28298
CHODL chondrolectin 2.28298
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2 2.28298
FBXO44 F-box protein 44 2.28298
CUL7 cullin 7 2.28298
SP140 SP140 nuclear body protein 2.28298
ARHGAP9 Rho GTPase activating protein 9 2.28298
CBLN1 cerebellin 1 precursor 2.28298
LRRC8C leucine rich repeat containing 8 family, member C 2.28298
EXOC3L2 exocyst complex component 3-like 2 2.28298
RNF19B ring finger protein 19B 2.28298
PXMP4 peroxisomal membrane protein 4, 24kDa 2.28298
MAPKBP1 mitogen-activated protein kinase binding protein 1 2.28298
CXCR5 chemokine (C-X-C motif) receptor 5 2.28298
EME2 essential meiotic structure-specific endonuclease subunit 2 2.28298
TIGD1 tigger transposable element derived 1 2.28298
FJX1 four jointed box 1 (Drosophila) 2.28298
IL20RA interleukin 20 receptor, alpha 2.28298
CLMB calcimembrin 2.28298
AFAP1L2 actin filament associated protein 1-like 2 2.28298
KDF1 keratinocyte differentiation factor 1 2.28298
PROSER2 proline and serine rich 2 2.28298
MAGEE1 melanoma antigen family E1 2.28298
RIC8A RIC8 guanine nucleotide exchange factor A 2.28298
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 2.28298
CCDC184 coiled-coil domain containing 184 2.28298
RUMY3 RUMY family member 3 2.28298
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3 2.28298
KLRB1 killer cell lectin-like receptor subfamily B, member 1 2.28298
FAM50B family with sequence similarity 50, member B 2.28298
PHYHIP phytanoyl-CoA 2-hydroxylase interacting protein 2.28298
ACBD4 acyl-CoA binding domain containing 4 2.28298
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1 2.28298
FICD FIC domain containing 2.28298
REC8 REC8 meiotic recombination protein 2.28298
TFAP2E transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon) 2.28298
TMCC3 transmembrane and coiled-coil domain family 3 2.28298
CCDC159 coiled-coil domain containing 159 2.28298
CCDC152 coiled-coil domain containing 152 2.28298
ALPK1 alpha-kinase 1 2.28298
SH3BGR SH3 domain binding glutamate-rich protein 2.28298
ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8 2.28298
MZT2A mitotic spindle organizing protein 2A 2.28298
DNAH10 dynein, axonemal, heavy chain 10 2.28298
ADCY7 adenylate cyclase 7 2.28298
SATL1 spermidine/spermine N1-acetyl transferase-like 1 2.28298
TNXB tenascin XB 2.28298
TCTN2 tectonic family member 2 2.28298
ISL2 ISL LIM homeobox 2 2.28298
ZCCHC18 zinc finger, CCHC domain containing 18 2.28298
RMDN2 regulator of microtubule dynamics 2 2.28298
LRRC37A2 leucine rich repeat containing 37, member A2 2.28298
TRIM3 tripartite motif containing 3 2.28298
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 2.28298
SLC25A30 solute carrier family 25, member 30 2.28298
C1ORF105 chromosome 1 open reading frame 105 2.28298
WDR13 WD repeat domain 13 2.28298
ZNF383 zinc finger protein 383 2.28298
WIF1 WNT inhibitory factor 1 2.28298
RBPJL recombination signal binding protein for immunoglobulin kappa J region-like 2.28298
SLC35F4 solute carrier family 35, member F4 2.28298
TMEM253 transmembrane protein 253 2.28298
TESC tescalcin 2.28298
PLAC8L1 PLAC8-like 1 2.28298
SHANK1 SH3 and multiple ankyrin repeat domains 1 2.28298
ZBTB7B zinc finger and BTB domain containing 7B 2.28298
MAP10 microtubule-associated protein 10 2.28298
TTC27 tetratricopeptide repeat domain 27 2.28298
TCAP titin-cap 2.28298
RGS8 regulator of G-protein signaling 8 2.28298
FBN1 fibrillin 1 2.28298
PDZRN4 PDZ domain containing ring finger 4 2.28298
MRPL15 mitochondrial ribosomal protein L15 2.28298
FBXO43 F-box protein 43 2.28298
TTC12 tetratricopeptide repeat domain 12 2.28298
AHDC1 AT hook, DNA binding motif, containing 1 2.28298
ILDR2 immunoglobulin-like domain containing receptor 2 2.28298
ARFRP1 ADP-ribosylation factor related protein 1 2.28298
TCTA T-cell leukemia translocation altered 2.28298
MXRA5 matrix-remodelling associated 5 2.28298
RIPPLY3 ripply transcriptional repressor 3 2.28298
RWDD2A RWD domain containing 2A 2.28298
BCORL1 BCL6 corepressor-like 1 2.28298
SMIM10 small integral membrane protein 10 2.28298
GDPD2 glycerophosphodiester phosphodiesterase domain containing 2 2.28298
FOXP4 forkhead box P4 2.28298
USP11 ubiquitin specific peptidase 11 2.28298
ADGRD2 adhesion G protein-coupled receptor D2 2.28298
SYT1 synaptotagmin I 2.28298
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 2.28298
PSD4 pleckstrin and Sec7 domain containing 4 2.28298
NRG4 neuregulin 4 2.28298
ICAM1 intercellular adhesion molecule 1 2.28298
TCF15 transcription factor 15 (basic helix-loop-helix) 2.28298
TXK TXK tyrosine kinase 2.28298
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2 2.28298
CLEC2L C-type lectin domain family 2, member L 2.28298
KCTD7 potassium channel tetramerization domain containing 7 2.28298
TAS2R43 taste receptor, type 2, member 43 2.28298
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae) 2.28298
INPP5K inositol polyphosphate-5-phosphatase K 2.28298
TOMM7 translocase of outer mitochondrial membrane 7 homolog (yeast) 2.28298
UBR5 ubiquitin protein ligase E3 component n-recognin 5 2.28298
PTPN5 protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched) 2.28298
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3 2.28298
C4ORF33 chromosome 4 open reading frame 33 2.28298
LCP1 lymphocyte cytosolic protein 1 (L-plastin) 2.28298
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 2.28298
RUMY2 RUMY family member 2 2.28298
NRXN3 neurexin 3 2.28298
XPA xeroderma pigmentosum, complementation group A 2.28298
FBXL16 F-box and leucine-rich repeat protein 16 2.28298
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) 2.28298
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal) 2.28298
STK36 serine/threonine kinase 36 2.28298
STK31 serine/threonine kinase 31 2.28298
RPH3A rabphilin 3A 2.28298
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 2.28298
GPR153 G protein-coupled receptor 153 2.28298
HACD4 3-hydroxyacyl-CoA dehydratase 4 2.28298
EXOC8 exocyst complex component 8 2.28298
CNDP1 carnosine dipeptidase 1 (metallopeptidase M20 family) 2.28298
CCDC82 coiled-coil domain containing 82 2.28298
PROM2 prominin 2 2.28298
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3) 2.28298
PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 2.28298
IRF2BP1 interferon regulatory factor 2 binding protein 1 2.28298
CHRM5 cholinergic receptor, muscarinic 5 2.28298
TRIM21 tripartite motif containing 21 2.28298
DOC2A double C2-like domains, alpha 2.28298
RAP1GAP2 RAP1 GTPase activating protein 2 2.28298
ARFGEF3 ARFGEF family member 3 2.28298
TMEM150A transmembrane protein 150A 2.28298
FUZ fuzzy planar cell polarity protein 2.28298
NRN1L neuritin 1-like 2.28298
EXOSC4 exosome component 4 2.28298
AK8 adenylate kinase 8 2.28298
ACKR4 atypical chemokine receptor 4 2.28298
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1 2.28298
NGF nerve growth factor (beta polypeptide) 2.28298
JMJD4 jumonji domain containing 4 2.28298
TBPL2 TATA box binding protein like 2 2.28298
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase 2.27824
ZCCHC3 zinc finger, CCHC domain containing 3 2.27731
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) 2.26912
MRPL11 mitochondrial ribosomal protein L11 2.26007
TMEM106B transmembrane protein 106B 2.26007
ING2 inhibitor of growth family, member 2 2.25918
CREB3L2 cAMP responsive element binding protein 3-like 2 2.25908
TTC19 tetratricopeptide repeat domain 19 2.2462
ANAPC5 anaphase promoting complex subunit 5 2.23936
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2 2.23924
SUZ12 SUZ12 polycomb repressive complex 2 subunit 2.2239
PRPF4 pre-mRNA processing factor 4 2.21543
QTRT1 queuine tRNA-ribosyltransferase 1 2.20921
NDEL1 nudE neurodevelopment protein 1-like 1 2.20921
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 2.19207
EXOC7 exocyst complex component 7 2.18808
TMEM115 transmembrane protein 115 2.18375
GPR27 G protein-coupled receptor 27 2.18375
GSDMB gasdermin B 2.18375
DRC10 dynein regulatory complex subunit 10 2.18375
MED8 mediator complex subunit 8 2.18375
ENO4 enolase family member 4 2.18375
MMP26 matrix metallopeptidase 26 2.18375
DPPA5 developmental pluripotency associated 5 2.18375
RILP Rab interacting lysosomal protein 2.18375
CRLF2 cytokine receptor-like factor 2 2.18375
MGST2 microsomal glutathione S-transferase 2 2.18375
RPP14 ribonuclease P/MRP 14kDa subunit 2.18375
SAYSD1 SAYSVFN motif domain containing 1 2.18375
HSD17B7 hydroxysteroid (17-beta) dehydrogenase 7 2.18375
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific 2.18375
CATSPERG catsper channel auxiliary subunit gamma 2.18375
CACNG6 calcium channel, voltage-dependent, gamma subunit 6 2.18375
CNKSR1 connector enhancer of kinase suppressor of Ras 1 2.18375
TAGLN3 transgelin 3 2.18375
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box) 2.15953
SSBP2 single-stranded DNA binding protein 2 2.15226
C1ORF52 chromosome 1 open reading frame 52 2.15226
TRAF3IP2 TRAF3 interacting protein 2 2.12509
DTNBP1 dystrobrevin binding protein 1 2.12509
TBKBP1 TBK1 binding protein 1 2.12509
BANP BTG3 associated nuclear protein 2.12509
TMEM126A transmembrane protein 126A 2.12509
STX7 syntaxin 7 2.12509
ZNF682 zinc finger protein 682 2.12509
HPN hepsin 2.12509
RBM15 RNA binding motif protein 15 2.12509
TMEM69 transmembrane protein 69 2.12509
H4C8 H4 clustered histone 8 2.12509
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4 2.12509
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 2.12509
ESRRA estrogen-related receptor alpha 2.12509
ATG13 autophagy related 13 2.12509
SRGAP2C SLIT-ROBO Rho GTPase activating protein 2C 2.12509
GSTK1 glutathione S-transferase kappa 1 2.12293
GDPGP1 GDP-D-glucose phosphorylase 1 2.12293
CHRNE cholinergic receptor, nicotinic, epsilon (muscle) 2.12293
NDST3 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3 2.12293
CD58 CD58 molecule 2.12293
FANCL Fanconi anemia, complementation group L 2.12293
PTPN23 protein tyrosine phosphatase, non-receptor type 23 2.12293
GFRA1 GDNF family receptor alpha 1 2.12293
ENC1 ectodermal-neural cortex 1 (with BTB domain) 2.12293
LIN7B lin-7 homolog B (C. elegans) 2.12293
PPIL6 peptidylprolyl isomerase (cyclophilin)-like 6 2.12293
ZNF385C zinc finger protein 385C 2.12293
PHACTR4 phosphatase and actin regulator 4 2.08737
COG7 component of oligomeric golgi complex 7 2.05492
MTM1 myotubularin 1 2.05492
YTHDC2 YTH domain containing 2 2.05469
ORAI1 ORAI calcium release-activated calcium modulator 1 2.01309
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 2.01309
DDX41 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 2.01309
H1-10 H1.10 linker histone 2.01207
SMAD5 SMAD family member 5 2.00991
RNF180 ring finger protein 180 2.00752

decreased expression

Symbol Name Standardized Value
AK5 adenylate kinase 5 -2.35352
RAB1B RAB1B, member RAS oncogene family -2.35352
DCUN1D3 DCN1, defective in cullin neddylation 1, domain containing 3 -2.35352
ZNF367 zinc finger protein 367 -2.35352
STEEP1 STING1 ER exit protein 1 -2.35352
TADA2A transcriptional adaptor 2A -2.35352
POGLUT1 protein O-glucosyltransferase 1 -2.35352
NES nestin -2.35352
CCDC134 coiled-coil domain containing 134 -2.35352
DCAF11 DDB1 and CUL4 associated factor 11 -2.35352
CCBE1 collagen and calcium binding EGF domains 1 -2.35352
ANXA6 annexin A6 -2.34401
POLE polymerase (DNA directed), epsilon, catalytic subunit -2.34401
GPRIN2 G protein regulated inducer of neurite outgrowth 2 -2.34401
METTL6 methyltransferase like 6 -2.34401
BKGD beta-keto-L-gulonate decarboxylase -2.34401
COL11A1 collagen, type XI, alpha 1 -2.34401
NMU neuromedin U -2.34401
TPD52L2 tumor protein D52-like 2 -2.34401
CEP55 centrosomal protein 55kDa -2.34401
PDLIM2 PDZ and LIM domain 2 (mystique) -2.34401
PRRT2 proline-rich transmembrane protein 2 -2.31404
ARHGAP29 Rho GTPase activating protein 29 -2.31404
SLC71A1 solute carrier family 71 member 1 -2.31404
PDCL phosducin-like -2.31404
MCTP1 multiple C2 domains, transmembrane 1 -2.31404
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit -2.31404
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 -2.31404
MARCHF5 membrane associated ring-CH-type finger 5 -2.31404
TRIM14 tripartite motif containing 14 -2.28298
RTN4R reticulon 4 receptor -2.28298
C4ORF46 chromosome 4 open reading frame 46 -2.28298
AOX1 aldehyde oxidase 1 -2.28298
CD160 CD160 molecule -2.28298
PIGP phosphatidylinositol glycan anchor biosynthesis, class P -2.28298
PDLIM3 PDZ and LIM domain 3 -2.28298
NUDT14 nudix (nucleoside diphosphate linked moiety X)-type motif 14 -2.28298
PRICKLE2 prickle homolog 2 (Drosophila) -2.28298
SHB Src homology 2 domain containing adaptor protein B -2.28298
MED25 mediator complex subunit 25 -2.28298
ZBTB2 zinc finger and BTB domain containing 2 -2.28298
PASK PAS domain containing serine/threonine kinase -2.28298
CLEC11A C-type lectin domain family 11, member A -2.28298
SMAP2 small ArfGAP2 -2.28298
REXO1 REX1, RNA exonuclease 1 homolog (S. cerevisiae) -2.28298
ARHGAP11B Rho GTPase activating protein 11B -2.28298
BET1 Bet1 golgi vesicular membrane trafficking protein -2.28298
SOX12 SRY (sex determining region Y)-box 12 -2.28298
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2 -2.28298
FMN1 formin 1 -2.28298
ATP1B2 ATPase, Na+/K+ transporting, beta 2 polypeptide -2.28298
MED11 mediator complex subunit 11 -2.28298
EFNA4 ephrin-A4 -2.28298
SUSD1 sushi domain containing 1 -2.28298
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2 -2.28298
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -2.28298
EPHX2 epoxide hydrolase 2, cytoplasmic -2.28298
BSN bassoon presynaptic cytomatrix protein -2.28298
SDF2 stromal cell-derived factor 2 -2.28298
RDH14 retinol dehydrogenase 14 (all-trans/9-cis/11-cis) -2.28298
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2 -2.28298
ZBTB40 zinc finger and BTB domain containing 40 -2.28298
STRIP1 striatin interacting protein 1 -2.28298
STRIP2 striatin interacting protein 2 -2.28298
MFF mitochondrial fission factor -2.28298
CPT1C carnitine palmitoyltransferase 1C -2.28298
VAMP4 vesicle-associated membrane protein 4 -2.28298
SLC33A2 solute carrier family 33 member 2 -2.28298
BEND7 BEN domain containing 7 -2.28298
RCAN1 regulator of calcineurin 1 -2.28298
POMGNT2 protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-) -2.28298
PRRC2A proline-rich coiled-coil 2A -2.28298
CAPN5 calpain 5 -2.28298
CEP85L centrosomal protein 85kDa-like -2.28298
HTRA2 HtrA serine peptidase 2 -2.28298
UBXN2B UBX domain protein 2B -2.28298
ELOVL1 ELOVL fatty acid elongase 1 -2.28298
MNMIP1 manchette microtubule inner protein 1 -2.28298
PI4KB phosphatidylinositol 4-kinase, catalytic, beta -2.28298
MACO1 macoilin 1 -2.28298
INTS11 integrator complex subunit 11 -2.28298
B4GAT1-DT B4GAT1 divergent transcript -2.28298
FERRY3 FERRY endosomal RAB5 effector complex subunit 3 -2.28298
GVQW3 GVQW motif containing 3 -2.28298
H2AC7 H2A clustered histone 7 -2.28298
H2AC16 H2A clustered histone 16 -2.28298
MATCAP1 microtubule associated tyrosine carboxypeptidase 1 -2.28298
LYSET lysosomal enzyme trafficking factor -2.28298
EEIG1 estrogen-induced osteoclastogenesis regulator 1 -2.28298
SRPRA SRP receptor subunit alpha -2.28298
FAM241B family with sequence similarity 241 member B -2.28298
C9ORF40 chromosome 9 open reading frame 40 -2.28298
HUS1 HUS1 checkpoint homolog (S. pombe) -2.28298
USP43 ubiquitin specific peptidase 43 -2.28298
CCDC125 coiled-coil domain containing 125 -2.28298
MTFMT mitochondrial methionyl-tRNA formyltransferase -2.28298
SLCO4A1 solute carrier organic anion transporter family, member 4A1 -2.28298
CYB561 cytochrome b561 -2.28298
YAE1 YAE1 maturation factor of ABCE1 -2.28298
SLC35D2 solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2 -2.28298
HINT3 histidine triad nucleotide binding protein 3 -2.28298
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit -2.28298
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 -2.28298
PIGX phosphatidylinositol glycan anchor biosynthesis, class X -2.28298
GOLPH3 golgi phosphoprotein 3 (coat-protein) -2.28298
ARHGAP18 Rho GTPase activating protein 18 -2.28298
HID1 HID1 domain containing -2.28298
ZSCAN32 zinc finger and SCAN domain containing 32 -2.28298
SFT2D3 SFT2 domain containing 3 -2.28298
TMEM263 transmembrane protein 263 -2.28298
RAB3D RAB3D, member RAS oncogene family -2.28298
CARM1 coactivator-associated arginine methyltransferase 1 -2.28298
BST1 bone marrow stromal cell antigen 1 -2.28298
ANKRD13A ankyrin repeat domain 13A -2.28298
PDIK1L PDLIM1 interacting kinase 1 like -2.28298
PNPLA8 patatin-like phospholipase domain containing 8 -2.28298
OXLD1 oxidoreductase-like domain containing 1 -2.28298
RIT2 Ras-like without CAAX 2 -2.28298
RNF6 ring finger protein (C3H2C3 type) 6 -2.28298
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 -2.28298
KBTBD4 kelch repeat and BTB (POZ) domain containing 4 -2.28298
OGFRL1 opioid growth factor receptor-like 1 -2.28298
ZNF7 zinc finger protein 7 -2.28298
NEIL2 nei endonuclease VIII-like 2 (E. coli) -2.28298
FYCO1 FYVE and coiled-coil domain containing 1 -2.28298
GADD45G growth arrest and DNA-damage-inducible, gamma -2.28298
ANTXR2 anthrax toxin receptor 2 -2.28298
ANKMY2 ankyrin repeat and MYND domain containing 2 -2.28298
KCNK1 potassium channel, two pore domain subfamily K, member 1 -2.28298
CCDC51 coiled-coil domain containing 51 -2.28298
CRYBG3 beta-gamma crystallin domain containing 3 -2.28298
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12 -2.28298
AGO4 argonaute RISC catalytic component 4 -2.28298
USHBP1 Usher syndrome 1C binding protein 1 -2.28298
RUFY1 RUN and FYVE domain containing 1 -2.28298
GNG7 guanine nucleotide binding protein (G protein), gamma 7 -2.28298
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2 -2.28298
KBTBD7 kelch repeat and BTB (POZ) domain containing 7 -2.28298
FANCE Fanconi anemia, complementation group E -2.28298
FAHD2B fumarylacetoacetate hydrolase domain containing 2B -2.28298
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast) -2.28298
RNF128 ring finger protein 128, E3 ubiquitin protein ligase -2.28298
CHKB choline kinase beta -2.28298
ZNF81 zinc finger protein 81 -2.28298
ERCC4 excision repair cross-complementation group 4 -2.28298
APELA apelin receptor early endogenous ligand -2.28298
SNX30 sorting nexin family member 30 -2.28298
ZFP14 ZFP14 zinc finger protein -2.28298
RAB5C RAB5C, member RAS oncogene family -2.28298
APOLTP apolipoprotein lipid transfer particle homolog -2.28298
SLC4A1AP solute carrier family 4 (anion exchanger), member 1, adaptor protein -2.28298
CEBPB CCAAT/enhancer binding protein (C/EBP), beta -2.28298
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa -2.28298
CRTAC1 cartilage acidic protein 1 -2.28298
MXI1 MAX interactor 1, dimerization protein -2.28298
DNAJC10 DnaJ (Hsp40) homolog, subfamily C, member 10 -2.28298
AMOTL1 angiomotin like 1 -2.28298
INF2 inverted formin, FH2 and WH2 domain containing -2.28298
WDR49 WD repeat domain 49 -2.28298
GFER growth factor, augmenter of liver regeneration -2.28298
CCDC90B coiled-coil domain containing 90B -2.28298
SLC27A1 solute carrier family 27 (fatty acid transporter), member 1 -2.28298
TRAPPC6B trafficking protein particle complex 6B -2.28298
OTULIN OTU deubiquitinase with linear linkage specificity -2.28298
DHRS4 dehydrogenase/reductase (SDR family) member 4 -2.28298
ATP2C2 ATPase, Ca++ transporting, type 2C, member 2 -2.28298
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 -2.28298
ZNF655 zinc finger protein 655 -2.28298
R3HCC1 R3H domain and coiled-coil containing 1 -2.28298
STYXL1 serine/threonine/tyrosine interacting-like 1 -2.28298
NKD1 naked cuticle homolog 1 (Drosophila) -2.28298
MMP24 matrix metallopeptidase 24 (membrane-inserted) -2.28298
SPRED3 sprouty-related, EVH1 domain containing 3 -2.28298
SBF1 SET binding factor 1 -2.28298
RASSF7 Ras association (RalGDS/AF-6) domain family (N-terminal) member 7 -2.28298
GSDMD gasdermin D -2.28298
SLC39A13 solute carrier family 39 (zinc transporter), member 13 -2.28298
MRPL24 mitochondrial ribosomal protein L24 -2.28298
MIF4GD MIF4G domain containing -2.28298
WDR20 WD repeat domain 20 -2.28298
IFT43 intraflagellar transport 43 -2.28298
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6 -2.28298
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 -2.28298
NRCAM neuronal cell adhesion molecule -2.28298
ERAL1 Era-like 12S mitochondrial rRNA chaperone 1 -2.28298
TSPYL4 TSPY-like 4 -2.28298
UBIAD1 UbiA prenyltransferase domain containing 1 -2.28298
MED30 mediator complex subunit 30 -2.28298
EPOR erythropoietin receptor -2.28298
PURB purine-rich element binding protein B -2.28298
CTSD cathepsin D -2.28298
CA5B carbonic anhydrase VB, mitochondrial -2.28298
POMT1 protein-O-mannosyltransferase 1 -2.28298
NUDT22 nudix (nucleoside diphosphate linked moiety X)-type motif 22 -2.28298
KLHL26 kelch-like family member 26 -2.28298
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2 -2.28298
RGS3 regulator of G-protein signaling 3 -2.28298
ANXA4 annexin A4 -2.28298
YBX2 Y box binding protein 2 -2.28298
ZNF317 zinc finger protein 317 -2.28298
DUS4L dihydrouridine synthase 4-like (S. cerevisiae) -2.28298
NUP35 nucleoporin 35kDa -2.25561
CHMP1B charged multivesicular body protein 1B -2.25212
RWDD1 RWD domain containing 1 -2.23564
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa -2.22462
DSEL dermatan sulfate epimerase-like -2.21848
MINDY3 MINDY lysine 48 deubiquitinase 3 -2.21848
TP53BP2 tumor protein p53 binding protein 2 -2.21409
VPS37A vacuolar protein sorting 37 homolog A (S. cerevisiae) -2.20287
STIP1 stress-induced phosphoprotein 1 -2.18375
PHF6 PHD finger protein 6 -2.16322
MICU1 mitochondrial calcium uptake 1 -2.15141
NAXE NAD(P)HX epimerase -2.12509
NT5C 5', 3'-nucleotidase, cytosolic -2.12509
ZNF426 zinc finger protein 426 -2.12509
NCOA6 nuclear receptor coactivator 6 -2.12509
PDLIM1 PDZ and LIM domain 1 -2.12509
THSD7A thrombospondin, type I, domain containing 7A -2.12509
LCMT2 leucine carboxyl methyltransferase 2 -2.12509
NOP2 NOP2 nucleolar protein -2.12509
DNAH14 dynein, axonemal, heavy chain 14 -2.12509
ZNF223 zinc finger protein 223 -2.12293
NEU1 sialidase 1 (lysosomal sialidase) -2.12293
RBM7 RNA binding motif protein 7 -2.12293
MRFAP1L2 Morf4 family associated protein 1 like 2 -2.12293
GUCD1 guanylyl cyclase domain containing 1 -2.12293
TJAP1 tight junction associated protein 1 (peripheral) -2.12293
SMO smoothened, frizzled class receptor -2.12293
UNC79 unc-79 homolog (C. elegans) -2.12293
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 -2.12293
RNF44 ring finger protein 44 -2.0974
MRPS18C mitochondrial ribosomal protein S18C -2.09588
CRLF3 cytokine receptor-like factor 3 -2.08493
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) -2.05788
ITM2C integral membrane protein 2C -2.05552
CPSF2 cleavage and polyadenylation specific factor 2, 100kDa -2.03668
FBXL4 F-box and leucine-rich repeat protein 4 -2.03668
CD164 CD164 molecule, sialomucin -2.03668
FASN fatty acid synthase -2.01436
CNPY3 canopy FGF signaling regulator 3 -2.01309
FARSA phenylalanyl-tRNA synthetase, alpha subunit -2.01207