PPIF Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description peptidylprolyl isomerase F|The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is part of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Activation of this pore is thought to be involved in the induction of apoptotic and necrotic cell death. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 10105)
External Link https://ncbi.nlm.nih.gov/gene/10105
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Genes

499 genes differentially expressed following the PPIF gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
TXNDC9 thioredoxin domain containing 9 0.0211826
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.0179904
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 0.0126405
AMIGO2 adhesion molecule with Ig-like domain 2 0.0125517
PLN phospholamban 0.0122424
JCHAIN joining chain of multimeric IgA and IgM 0.0120214
TFPI2 tissue factor pathway inhibitor 2 0.011968
BASP1 brain abundant, membrane attached signal protein 1 0.0119366
IFITM1 interferon induced transmembrane protein 1 0.0117299
LYZ lysozyme 0.0116774
PDLIM3 PDZ and LIM domain 3 0.0115973
THBS1 thrombospondin 1 0.0115083
PCNA proliferating cell nuclear antigen 0.011371
SLC44A4 solute carrier family 44, member 4 0.0112354
CCL5 chemokine (C-C motif) ligand 5 0.0110076
TMEM158 transmembrane protein 158 (gene/pseudogene) 0.0108683
CXCL9 chemokine (C-X-C motif) ligand 9 0.0107331
CPA3 carboxypeptidase A3 (mast cell) 0.0106448
PDZK1IP1 PDZK1 interacting protein 1 0.010621
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 0.0106064
EIF5A eukaryotic translation initiation factor 5A 0.0105524
NNMT nicotinamide N-methyltransferase 0.0103207
NME4 NME/NM23 nucleoside diphosphate kinase 4 0.00997559
LST1 leukocyte specific transcript 1 0.00996884
IL7R interleukin 7 receptor 0.00996369
IFRD2 interferon-related developmental regulator 2 0.00990707
PRKACB protein kinase, cAMP-dependent, catalytic, beta 0.0098041
AMH anti-Mullerian hormone 0.00979611
CXCL14 chemokine (C-X-C motif) ligand 14 0.00957725
DACH1 dachshund family transcription factor 1 0.00954376
RGS10 regulator of G-protein signaling 10 0.0094445
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 0.00940456
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) 0.00922722
PKM pyruvate kinase, muscle 0.00912775
TPM2 tropomyosin 2 (beta) 0.00901197
MAP7 microtubule-associated protein 7 0.00881301
DES desmin 0.00878356
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 0.008686
ACTN1 actinin, alpha 1 0.008686
P4HB prolyl 4-hydroxylase, beta polypeptide 0.0086265
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 0.00860403
VCAM1 vascular cell adhesion molecule 1 0.00858732
IDO1 indoleamine 2,3-dioxygenase 1 0.00848657
VBP1 von Hippel-Lindau binding protein 1 0.00839268
DEGS1 delta(4)-desaturase, sphingolipid 1 0.00836553
SRGN serglycin 0.00828164
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.00827954
COL4A5 collagen, type IV, alpha 5 0.0081016
SDC1 syndecan 1 0.00808572
FST follistatin 0.00807559
TSPYL5 TSPY-like 5 0.00805824
KIF20A kinesin family member 20A 0.00804252
OLFM4 olfactomedin 4 0.00798813
DMBT1 deleted in malignant brain tumors 1 0.00796738
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) 0.00795993
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6 0.00795077
PCLAF PCNA clamp associated factor 0.0078781
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.00785119
CD48 CD48 molecule 0.00774462
TGFB1 transforming growth factor, beta 1 0.00773042
CCR2 chemokine (C-C motif) receptor 2 0.00770449
C3ORF14 chromosome 3 open reading frame 14 0.00770228
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 0.0075871
CASP1 caspase 1, apoptosis-related cysteine peptidase 0.00757309
BIRC5 baculoviral IAP repeat containing 5 0.00757108
LAPTM4B lysosomal protein transmembrane 4 beta 0.00753616
NIBAN1 niban apoptosis regulator 1 0.00751568
FASN fatty acid synthase 0.00748908
MSRB2 methionine sulfoxide reductase B2 0.00737974
SEC61G Sec61 gamma subunit 0.00736321
ACP5 acid phosphatase 5, tartrate resistant 0.00735763
C1QTNF3 C1q and tumor necrosis factor related protein 3 0.00733409
CYBB cytochrome b-245, beta polypeptide 0.00732234
NXN nucleoredoxin 0.00731817
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide 0.007312
CRYM crystallin, mu 0.00728393
DCXR dicarbonyl/L-xylulose reductase 0.00728208
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15 0.00727513
GZMK granzyme K (granzyme 3; tryptase II) 0.00727062
HBD hemoglobin, delta 0.00725166
CD2 CD2 molecule 0.00724728
TARP TCR gamma alternate reading frame protein 0.00724043
LGALS13 lectin, galactoside-binding, soluble, 13 0.00722237
CST7 cystatin F (leukocystatin) 0.0071813
MMP7 matrix metallopeptidase 7 0.00717048
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 0.00716957
CLC Charcot-Leyden crystal galectin 0.00716458
STK10 serine/threonine kinase 10 0.00716217
CRIP2 cysteine-rich protein 2 0.00715476
ACP3 acid phosphatase 3 0.00714002
SH3BGRL SH3 domain binding glutamate-rich protein like 0.00711964
NBL1 neuroblastoma 1, DAN family BMP antagonist 0.00710325
SRM spermidine synthase 0.00707287
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 0.00706962
RANBP1 RAN binding protein 1 0.00705971
HMGB3 high mobility group box 3 0.0070492
MCM6 minichromosome maintenance complex component 6 0.00702419
DSE dermatan sulfate epimerase 0.00702024
SNRPG small nuclear ribonucleoprotein polypeptide G 0.00701948
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 0.00701231
COL4A6 collagen, type IV, alpha 6 0.00698326
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) 0.00694656
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 0.00692967
NUSAP1 nucleolar and spindle associated protein 1 0.00692489
HPRT1 hypoxanthine phosphoribosyltransferase 1 0.00689492
PDLIM7 PDZ and LIM domain 7 (enigma) 0.00686644
SNRNP25 small nuclear ribonucleoprotein 25kDa (U11/U12) 0.00686512
EMP3 epithelial membrane protein 3 0.00685902
NRGN neurogranin (protein kinase C substrate, RC3) 0.00683954
SLC2A4RG SLC2A4 regulator 0.00683815
MGAM maltase-glucoamylase 0.00682619
AGTR1 angiotensin II receptor, type 1 0.00681133
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.00678941
PHTF2 putative homeodomain transcription factor 2 0.00678806
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 0.00678231
KLRB1 killer cell lectin-like receptor subfamily B, member 1 0.00677664
FAM162A family with sequence similarity 162, member A 0.00675589
NSDHL NAD(P) dependent steroid dehydrogenase-like 0.00673232
LMNB2 lamin B2 0.00673028
HCP5 HLA complex P5 (non-protein coding) 0.00669938
TSPOAP1 TSPO associated protein 1 0.00665382
NKG7 natural killer cell granule protein 7 0.00663175
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.00662356
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 0.00661706
NDUFA4 NDUFA4, mitochondrial complex associated 0.00661529
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.00659948
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 0.0065965
POLD2 polymerase (DNA directed), delta 2, accessory subunit 0.0065791
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 0.00656509
TMEM63A transmembrane protein 63A 0.00656082
SLC17A3 solute carrier family 17 (organic anion transporter), member 3 0.00653622
TK1 thymidine kinase 1, soluble 0.00652368
CFB complement factor B 0.0065207
GPRC5C G protein-coupled receptor, class C, group 5, member C 0.00651706
MZT2A mitotic spindle organizing protein 2A 0.00650387
GREM1 gremlin 1, DAN family BMP antagonist 0.00647037
CTPS1 CTP synthase 1 0.00644252
SIVA1 SIVA1, apoptosis-inducing factor 0.00643829
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) 0.00641811
LTB lymphotoxin beta (TNF superfamily, member 3) 0.00639498
GMPR guanosine monophosphate reductase 0.00638876
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 0.00638832
TRIM14 tripartite motif containing 14 0.00637572
PCP4 Purkinje cell protein 4 0.00637134
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) 0.00635734
CNN1 calponin 1, basic, smooth muscle 0.0063517
TCEAL1 transcription elongation factor A (SII)-like 1 0.00633873
PDGFC platelet derived growth factor C 0.00633723
AK4 adenylate kinase 4 0.00633258
CXCL11 chemokine (C-X-C motif) ligand 11 0.0063159
SORBS1 sorbin and SH3 domain containing 1 0.00631424
TMEM106C transmembrane protein 106C 0.00630607
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha 0.00630603
CCND2 cyclin D2 0.00630591
H2AFV H2A histone family, member V 0.00630194
DUSP3 dual specificity phosphatase 3 0.0063002
AXL AXL receptor tyrosine kinase 0.00628036
SLC39A8 solute carrier family 39 (zinc transporter), member 8 0.00626773
HYOU1 hypoxia up-regulated 1 0.00625868
GANAB glucosidase, alpha; neutral AB 0.00625684
DKK3 dickkopf WNT signaling pathway inhibitor 3 0.00624119
CCNB2 cyclin B2 0.00623485
SHMT1 serine hydroxymethyltransferase 1 (soluble) 0.00623096
ALOX5 arachidonate 5-lipoxygenase 0.00622856
POMZP3 POM121 and ZP3 fusion 0.00621538
EPHB2 EPH receptor B2 0.00620099
NTS neurotensin 0.00618901
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A 0.00618022
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit 0.00617511
MPHOSPH8 M-phase phosphoprotein 8 0.00616626
TSPAN4 tetraspanin 4 0.00616599
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) 0.00616498
CAMP cathelicidin antimicrobial peptide 0.00616446
ACE2 angiotensin I converting enzyme 2 0.00614246
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase 0.00613844
PYGB phosphorylase, glycogen; brain 0.00612402
SLCO3A1 solute carrier organic anion transporter family, member 3A1 0.00612209
FOXM1 forkhead box M1 0.00612196
RWDD1 RWD domain containing 1 0.00612038
MCUB mitochondrial calcium uniporter dominant negative subunit beta 0.0061075
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein 0.00610742
IFI6 interferon, alpha-inducible protein 6 0.00608996
FBP1 fructose-1,6-bisphosphatase 1 0.00605931
HOXB2 homeobox B2 0.00605921
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 0.00604575
ASF1B anti-silencing function 1B histone chaperone 0.00599458
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2 0.00598956
LY6E lymphocyte antigen 6 complex, locus E 0.005983
P3H4 prolyl 3-hydroxylase family member 4 (non-enzymatic) 0.00598258
SMTN smoothelin 0.00597086
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 0.00596559
AURKA aurora kinase A 0.00595309
RAB32 RAB32, member RAS oncogene family 0.00594465
THOC7 THO complex 7 0.00594223
FEN1 flap structure-specific endonuclease 1 0.00594063
OSBPL10 oxysterol binding protein-like 10 0.00593899
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase 0.00593371
RTN2 reticulon 2 0.00592382
PRDX2 peroxiredoxin 2 0.0059204
PRPF4 pre-mRNA processing factor 4 0.00590605
UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) 0.00589772
CHN2 chimerin 2 0.00588412
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.00588249
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme 0.00587812
KLK3 kallikrein-related peptidase 3 0.00587199
ACTR3 ARP3 actin-related protein 3 homolog (yeast) 0.00586994
CETN2 centrin, EF-hand protein, 2 0.00586016
NQO2 NAD(P)H dehydrogenase, quinone 2 0.00585496
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.00583943
THNSL2 threonine synthase-like 2 (S. cerevisiae) 0.00583724
NVL nuclear VCP-like 0.00578323
AHSP alpha hemoglobin stabilizing protein 0.00577958
ALG5 ALG5, dolichyl-phosphate beta-glucosyltransferase 0.00577621
CMPK1 cytidine monophosphate (UMP-CMP) kinase 1, cytosolic 0.00577149
PDE4D phosphodiesterase 4D, cAMP-specific 0.00576157
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C 0.00574146
TGFB1I1 transforming growth factor beta 1 induced transcript 1 0.00572175
TTC38 tetratricopeptide repeat domain 38 0.00571347
IFITM2 interferon induced transmembrane protein 2 0.00569753
LMNB1 lamin B1 0.00567221
TIMP1 TIMP metallopeptidase inhibitor 1 0.00566848
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 0.0056681
TEX30 testis expressed 30 0.00565873
SSR4 signal sequence receptor, delta 0.00565633
NEFH neurofilament, heavy polypeptide 0.00565343
COX7B cytochrome c oxidase subunit VIIb 0.00564378
FXYD2 FXYD domain containing ion transport regulator 2 0.0056353
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O 0.00561445
PRC1 protein regulator of cytokinesis 1 0.00560648
EIF3B eukaryotic translation initiation factor 3, subunit B 0.00560529
CNNM3 cyclin and CBS domain divalent metal cation transport mediator 3 0.00558941
TEAD4 TEA domain family member 4 0.00558627
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) 0.00558195
SUB1 SUB1 homolog (S. cerevisiae) 0.00557993
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3 0.00557978
CPB1 carboxypeptidase B1 (tissue) 0.00557584
CD300A CD300a molecule 0.00557396
CENPB centromere protein B, 80kDa 0.00556871
UBE2C ubiquitin-conjugating enzyme E2C 0.00556775
WT1 Wilms tumor 1 0.00555909
COL10A1 collagen, type X, alpha 1 0.00554095
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae) 0.00552842
PTPA protein phosphatase 2 phosphatase activator 0.00552782
PDE4A phosphodiesterase 4A, cAMP-specific 0.00549777
BET1 Bet1 golgi vesicular membrane trafficking protein 0.00549713
AMACR alpha-methylacyl-CoA racemase 0.00549043
GUSB glucuronidase, beta 0.00546859
TM7SF2 transmembrane 7 superfamily member 2 0.00546579
MRPL20 mitochondrial ribosomal protein L20 0.00546528
SLIRP SRA stem-loop interacting RNA binding protein 0.00545109

decreased expression

Symbol Name Standardized Value
MAGEA3 melanoma antigen family A3 -0.0215774
EMP1 epithelial membrane protein 1 -0.0159489
MAGEA12 melanoma antigen family A12 -0.0149849
DSP desmoplakin -0.0146669
STC2 stanniocalcin 2 -0.013462
ATF3 activating transcription factor 3 -0.0131867
PEG3 paternally expressed 3 -0.0115398
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -0.0114649
TCTA T-cell leukemia translocation altered -0.0114081
NRN1 neuritin 1 -0.0111905
PTN pleiotrophin -0.011102
CD99 CD99 molecule -0.0109523
IQCG IQ motif containing G -0.0107946
TUBB2B tubulin, beta 2B class IIb -0.0106426
EGR1 early growth response 1 -0.010441
SERINC5 serine incorporator 5 -0.0102804
RGCC regulator of cell cycle -0.010276
LEF1 lymphoid enhancer-binding factor 1 -0.0102538
TFRC transferrin receptor -0.0102217
KLF4 Kruppel-like factor 4 (gut) -0.0101799
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 -0.0101466
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 -0.010101
ASS1 argininosuccinate synthase 1 -0.00997113
GADD45A growth arrest and DNA-damage-inducible, alpha -0.00989129
KRT19 keratin 19, type I -0.0098534
SERTAD2 SERTA domain containing 2 -0.00971704
MSX1 msh homeobox 1 -0.00965322
MAGEA1 melanoma antigen family A1 -0.00933867
EFHD1 EF-hand domain family, member D1 -0.00925893
CXCL8 chemokine (C-X-C motif) ligand 8 -0.00924921
AHNAK AHNAK nucleoprotein -0.00923564
ANGPT2 angiopoietin 2 -0.00922641
FGA fibrinogen alpha chain -0.00920893
CHI3L2 chitinase 3-like 2 -0.00916643
BEX1 brain expressed, X-linked 1 -0.0091131
PLCE1 phospholipase C, epsilon 1 -0.00907438
KRT14 keratin 14, type I -0.00905901
KLF6 Kruppel-like factor 6 -0.00891955
VSNL1 visinin-like 1 -0.0088419
PALLD palladin, cytoskeletal associated protein -0.00871835
SEPP1 selenoprotein P, plasma, 1 -0.00870166
RALBP1 ralA binding protein 1 -0.00862697
ANK2 ankyrin 2, neuronal -0.00862358
RGS5 regulator of G-protein signaling 5 -0.00858787
SRPX sushi-repeat containing protein, X-linked -0.00857656
VWF von Willebrand factor -0.00851386
EGR2 early growth response 2 -0.00839043
FOXO1 forkhead box O1 -0.00838247
SSX1 synovial sarcoma, X breakpoint 1 -0.00831585
NOTCH3 notch 3 -0.00829678
SLC35G2 solute carrier family 35, member G2 -0.0082762
NRCAM neuronal cell adhesion molecule -0.00824563
TMEM176B transmembrane protein 176B -0.00821724
RAB11FIP1 RAB11 family interacting protein 1 (class I) -0.0081951
TSPAN7 tetraspanin 7 -0.00819376
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 -0.00819117
JUNB jun B proto-oncogene -0.00818768
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 -0.0081214
CDH5 cadherin 5, type 2 (vascular endothelium) -0.00807892
STC1 stanniocalcin 1 -0.00805158
CLDND1 claudin domain containing 1 -0.00803173
COL14A1 collagen, type XIV, alpha 1 -0.00797806
LY6D lymphocyte antigen 6 complex, locus D -0.00797275
APOLD1 apolipoprotein L domain containing 1 -0.00793982
ABHD3 abhydrolase domain containing 3 -0.00791892
MCM2 minichromosome maintenance complex component 2 -0.00791795
GPM6B glycoprotein M6B -0.00788094
MEX3C mex-3 RNA binding family member C -0.00786051
PPP1R15A protein phosphatase 1, regulatory subunit 15A -0.00784363
ASCL1 achaete-scute family bHLH transcription factor 1 -0.0078064
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) -0.0077953
KLF2 Kruppel-like factor 2 -0.00777091
GBAP1 glucosidase, beta, acid pseudogene 1 -0.00776745
PDGFRA platelet-derived growth factor receptor, alpha polypeptide -0.00772562
FXR1 fragile X mental retardation, autosomal homolog 1 -0.00771758
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 -0.00771022
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 -0.00770642
GLUL glutamate-ammonia ligase -0.00768958
PRDX1 peroxiredoxin 1 -0.00764063
PLPP3 phospholipid phosphatase 3 -0.00763008
STMN2 stathmin 2 -0.00762187
SPARCL1 SPARC-like 1 (hevin) -0.00762048
IL1R2 interleukin 1 receptor, type II -0.00758174
SYBU syntabulin (syntaxin-interacting) -0.00757509
EDNRB endothelin receptor type B -0.00757329
FGG fibrinogen gamma chain -0.00754848
ELMO1 engulfment and cell motility 1 -0.00747046
CNOT4 CCR4-NOT transcription complex, subunit 4 -0.00746875
FGB fibrinogen beta chain -0.00745683
ZNF281 zinc finger protein 281 -0.00744245
GPC3 glypican 3 -0.00744134
DKK1 dickkopf WNT signaling pathway inhibitor 1 -0.00743821
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -0.0074374
MTUS1 microtubule associated tumor suppressor 1 -0.00743017
SNAP25 synaptosomal-associated protein, 25kDa -0.00742952
PNISR PNN-interacting serine/arginine-rich protein -0.00741616
LAMA2 laminin, alpha 2 -0.00741368
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 -0.00738192
PEG10 paternally expressed 10 -0.00737882
ZIC1 Zic family member 1 -0.00735825
PTCH1 patched 1 -0.0073362
CHIC2 cysteine-rich hydrophobic domain 2 -0.00733356
DLK1 delta-like 1 homolog (Drosophila) -0.00730031
IFI27 interferon, alpha-inducible protein 27 -0.00729228
ZMIZ1 zinc finger, MIZ-type containing 1 -0.00728643
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 -0.00727252
F13A1 coagulation factor XIII, A1 polypeptide -0.00726886
CD93 CD93 molecule -0.0072603
AHCYL2 adenosylhomocysteinase-like 2 -0.00723989
ABLIM1 actin binding LIM protein 1 -0.00723455
MXRA5 matrix-remodelling associated 5 -0.00720539
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 -0.00719478
KLHL24 kelch-like family member 24 -0.00719047
TWIST1 twist family bHLH transcription factor 1 -0.00717657
BMP2 bone morphogenetic protein 2 -0.00715159
ABAT 4-aminobutyrate aminotransferase -0.00714755
SWAP70 SWAP switching B-cell complex 70kDa subunit -0.00713568
ELF1 E74-like factor 1 (ets domain transcription factor) -0.00712308
SPRR2B small proline-rich protein 2B -0.00707074
APOA2 apolipoprotein A-II -0.00706788
MAL mal, T-cell differentiation protein -0.00705236
KRT16 keratin 16, type I -0.00703424
ANGPT1 angiopoietin 1 -0.00700008
TOX thymocyte selection-associated high mobility group box -0.00699136
SELE selectin E -0.00698773
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 -0.00698121
TCF4 transcription factor 4 -0.00696206
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II -0.00695522
KLF9 Kruppel-like factor 9 -0.00690743
HMOX1 heme oxygenase 1 -0.00688541
GLDC glycine dehydrogenase (decarboxylating) -0.0068644
CSRP2 cysteine and glycine-rich protein 2 -0.00684296
CCNG2 cyclin G2 -0.00683268
KLK10 kallikrein-related peptidase 10 -0.00681324
MEN1 multiple endocrine neoplasia I -0.00680204
CLDN7 claudin 7 -0.00680065
HEATR1 HEAT repeat containing 1 -0.0067971
HSPB1 heat shock 27kDa protein 1 -0.00678598
RIMS3 regulating synaptic membrane exocytosis 3 -0.00678126
LDB2 LIM domain binding 2 -0.00677225
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) -0.00676785
IL1RN interleukin 1 receptor antagonist -0.00676689
RRAGD Ras-related GTP binding D -0.00676344
FCGBP Fc fragment of IgG binding protein -0.00675217
HOMER1 homer scaffolding protein 1 -0.00675119
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 -0.00674567
OLFML2A olfactomedin-like 2A -0.00672479
CAST calpastatin -0.0067178
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 -0.00669538
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) -0.00668142
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) -0.00666298
MPPED2 metallophosphoesterase domain containing 2 -0.00665674
RAB25 RAB25, member RAS oncogene family -0.00661974
OPHN1 oligophrenin 1 -0.00661372
DHRS2 dehydrogenase/reductase (SDR family) member 2 -0.00660639
TTC17 tetratricopeptide repeat domain 17 -0.00660334
PCDH17 protocadherin 17 -0.00660264
PMP2 peripheral myelin protein 2 -0.0065963
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B -0.00659269
PCDH9 protocadherin 9 -0.00658932
CLCA4 chloride channel accessory 4 -0.00656569
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.00655781
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 -0.00655114
SYNE3 spectrin repeat containing, nuclear envelope family member 3 -0.00652464
ADA adenosine deaminase -0.00651761
GABRP gamma-aminobutyric acid (GABA) A receptor, pi -0.00650557
NES nestin -0.00648565
DOCK9 dedicator of cytokinesis 9 -0.0064656
PRSS12 protease, serine, 12 (neurotrypsin, motopsin) -0.00644964
ZFP36L2 ZFP36 ring finger protein-like 2 -0.00644277
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 -0.00643257
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma -0.00641819
WEE1 WEE1 G2 checkpoint kinase -0.00639788
ALB albumin -0.00638065
FRS2 fibroblast growth factor receptor substrate 2 -0.00637526
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) -0.00636037
EXOC7 exocyst complex component 7 -0.00635822
WSB2 WD repeat and SOCS box containing 2 -0.00634223
IQGAP2 IQ motif containing GTPase activating protein 2 -0.00630109
OLFML2B olfactomedin-like 2B -0.00628671
CDH1 cadherin 1, type 1, E-cadherin (epithelial) -0.00628204
ZNF165 zinc finger protein 165 -0.00628095
FGF9 fibroblast growth factor 9 -0.00626878
PBX3 pre-B-cell leukemia homeobox 3 -0.00626559
DAAM1 dishevelled associated activator of morphogenesis 1 -0.00626441
NID2 nidogen 2 (osteonidogen) -0.00625607
ZNF83 zinc finger protein 83 -0.00625605
GAB2 GRB2-associated binding protein 2 -0.00623274
SAV1 salvador family WW domain containing protein 1 -0.00622129
HMBOX1 homeobox containing 1 -0.00622035
WDR19 WD repeat domain 19 -0.00621989
ZFP36 ZFP36 ring finger protein -0.00621578
KYNU kynureninase -0.00620639
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 -0.00620355
TPPP3 tubulin polymerization-promoting protein family member 3 -0.00620123
JMJD1C jumonji domain containing 1C -0.00620028
TENT5A terminal nucleotidyltransferase 5A -0.00620021
CH25H cholesterol 25-hydroxylase -0.00618794
NCK1 NCK adaptor protein 1 -0.00618138
IL6 interleukin 6 -0.00617846
TMEM176A transmembrane protein 176A -0.00617846
CALCA calcitonin-related polypeptide alpha -0.0061771
AKAP12 A kinase (PRKA) anchor protein 12 -0.00617524
ZMAT3 zinc finger, matrin-type 3 -0.00616815
YES1 YES proto-oncogene 1, Src family tyrosine kinase -0.00616576
GULP1 GULP, engulfment adaptor PTB domain containing 1 -0.00616038
AZIN1 antizyme inhibitor 1 -0.00615659
AFF1 AF4/FMR2 family, member 1 -0.00614916
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F -0.00613322
IRF6 interferon regulatory factor 6 -0.00613279
RSRC2 arginine/serine-rich coiled-coil 2 -0.00612932
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1) -0.00610828
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 -0.00610369
ENOPH1 enolase-phosphatase 1 -0.00609556
SPRR3 small proline-rich protein 3 -0.00609441
IRS2 insulin receptor substrate 2 -0.00607673
FAM198B family with sequence similarity 198, member B -0.00605416
MVP major vault protein -0.00604465
CFAP20 cilia and flagella associated protein 20 -0.00603537
SYT17 synaptotagmin XVII -0.00601987
TTR transthyretin -0.00598745
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.00598343
DUSP10 dual specificity phosphatase 10 -0.00597892
PLXND1 plexin D1 -0.00597793
F2RL1 coagulation factor II (thrombin) receptor-like 1 -0.00597684
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 -0.00597565
KLF7 Kruppel-like factor 7 (ubiquitous) -0.00597372
PCSK5 proprotein convertase subtilisin/kexin type 5 -0.00597314
SLPI secretory leukocyte peptidase inhibitor -0.00596838
RTCA RNA 3'-terminal phosphate cyclase -0.00596818
TAOK3 TAO kinase 3 -0.0059628
MXI1 MAX interactor 1, dimerization protein -0.00594633
MECOM MDS1 and EVI1 complex locus -0.00594503
TSC22D2 TSC22 domain family, member 2 -0.00594363
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -0.00594267
ITSN2 intersectin 2 -0.0059415
ADGRL4 adhesion G protein-coupled receptor L4 -0.0059393
FBXL12 F-box and leucine-rich repeat protein 12 -0.00593831
ATF4 activating transcription factor 4 -0.00593211
CLEC3B C-type lectin domain family 3, member B -0.00592103
TP53I3 tumor protein p53 inducible protein 3 -0.00591213
LAMA4 laminin, alpha 4 -0.00591088
CD14 CD14 molecule -0.0059059
KRT15 keratin 15, type I -0.0058947
FAM110B family with sequence similarity 110, member B -0.00589216
IGFBP5 insulin-like growth factor binding protein 5 -0.00588729
MAGEA4 melanoma antigen family A4 -0.00588659
FABP7 fatty acid binding protein 7, brain -0.00585623
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1 -0.00585517