| Dataset | Pathway Commons Protein-Protein Interactions |
| Category | physical interactions |
| Type | interacting protein |
| Description | protoporphyrinogen oxidase|This gene encodes the penultimate enzyme of heme biosynthesis, which catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX. Mutations in this gene cause variegate porphyria, an autosomal dominant disorder of heme metabolism resulting from a deficiency in protoporphyrinogen oxidase, an enzyme located on the inner mitochondrial membrane. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 5498) |
| External Link | http://www.ncbi.nlm.nih.gov/gene/5498 |
| Similar Terms | |
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5 interacting proteins for PPOX from the Pathway Commons Protein-Protein Interactions dataset.
