| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | protein phosphatase 1, catalytic subunit, alpha isozyme|The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 5499) |
| External Link | https://ncbi.nlm.nih.gov/gene/5499 |
| Similar Terms | |
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498 genes differentially expressed following the PPP1CA gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| XPO7 | exportin 7 | 0.0118278 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 0.0102923 |
| RCAN1 | regulator of calcineurin 1 | 0.0102407 |
| MT1X | metallothionein 1X | 0.0102095 |
| DAXX | death-domain associated protein | 0.00989275 |
| GRB7 | growth factor receptor-bound protein 7 | 0.00944477 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | 0.00912191 |
| TUBB2A | tubulin, beta 2A class IIa | 0.00907296 |
| FCGBP | Fc fragment of IgG binding protein | 0.00902414 |
| SCD5 | stearoyl-CoA desaturase 5 | 0.0090196 |
| ASS1 | argininosuccinate synthase 1 | 0.00893844 |
| C14ORF132 | chromosome 14 open reading frame 132 | 0.00875965 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 0.00874888 |
| SYBU | syntabulin (syntaxin-interacting) | 0.0086619 |
| CLU | clusterin | 0.00859247 |
| ETFB | electron-transfer-flavoprotein, beta polypeptide | 0.00859224 |
| CSRP2 | cysteine and glycine-rich protein 2 | 0.00856088 |
| TUBB2B | tubulin, beta 2B class IIb | 0.00853027 |
| LAMP3 | lysosomal-associated membrane protein 3 | 0.00845018 |
| ATF3 | activating transcription factor 3 | 0.00842869 |
| OPHN1 | oligophrenin 1 | 0.00842843 |
| PADI2 | peptidyl arginine deiminase, type II | 0.0082102 |
| CFI | complement factor I | 0.00793026 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 | 0.00790784 |
| HSPB1 | heat shock 27kDa protein 1 | 0.00782393 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0077682 |
| FAR2 | fatty acyl CoA reductase 2 | 0.00773094 |
| SELENBP1 | selenium binding protein 1 | 0.00771775 |
| HSPA1A | heat shock 70kDa protein 1A | 0.0076932 |
| CRABP1 | cellular retinoic acid binding protein 1 | 0.00767081 |
| S100A7 | S100 calcium binding protein A7 | 0.00759438 |
| SYT1 | synaptotagmin I | 0.00757316 |
| SELL | selectin L | 0.00756348 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | 0.00740999 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.00738359 |
| CAST | calpastatin | 0.00734869 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.00727066 |
| VAV3 | vav 3 guanine nucleotide exchange factor | 0.0072395 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.00721988 |
| KLF6 | Kruppel-like factor 6 | 0.00715167 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | 0.00713723 |
| AQP3 | aquaporin 3 (Gill blood group) | 0.00711784 |
| PNMA8A | PNMA family member 8A | 0.00707496 |
| RGCC | regulator of cell cycle | 0.00695597 |
| NRN1 | neuritin 1 | 0.00693301 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | 0.00690056 |
| XIC | X chromosome inactivation center | 0.00685859 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | 0.00684994 |
| MAB21L2 | mab-21-like 2 (C. elegans) | 0.00683443 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.00681859 |
| EFHD1 | EF-hand domain family, member D1 | 0.00675506 |
| MFAP3L | microfibrillar-associated protein 3-like | 0.00674004 |
| SH3YL1 | SH3 and SYLF domain containing 1 | 0.00659021 |
| IVNS1ABP | influenza virus NS1A binding protein | 0.00640409 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.00639793 |
| CA12 | carbonic anhydrase XII | 0.00638355 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | 0.00634499 |
| CRABP2 | cellular retinoic acid binding protein 2 | 0.00633152 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | 0.00632357 |
| S100A9 | S100 calcium binding protein A9 | 0.00631193 |
| E2F2 | E2F transcription factor 2 | 0.00629892 |
| PEBP1 | phosphatidylethanolamine binding protein 1 | 0.00628246 |
| DPEP1 | dipeptidase 1 (renal) | 0.00628077 |
| MX1 | MX dynamin-like GTPase 1 | 0.00627949 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 0.00624093 |
| TBX2 | T-box 2 | 0.00623893 |
| EIF6 | eukaryotic translation initiation factor 6 | 0.00611324 |
| DNTT | DNA nucleotidylexotransferase | 0.0060909 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | 0.00607367 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | 0.00605007 |
| S100A8 | S100 calcium binding protein A8 | 0.00599523 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 0.00598726 |
| FGFR4 | fibroblast growth factor receptor 4 | 0.00596442 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.00583117 |
| ABLIM1 | actin binding LIM protein 1 | 0.00582761 |
| OARD1 | O-acyl-ADP-ribose deacylase 1 | 0.00581949 |
| LMCD1 | LIM and cysteine-rich domains 1 | 0.00581724 |
| GAP43 | growth associated protein 43 | 0.00581693 |
| RFC5 | replication factor C (activator 1) 5, 36.5kDa | 0.0057991 |
| CXADR | coxsackie virus and adenovirus receptor | 0.00574572 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.00568906 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | 0.00567337 |
| MT2A | metallothionein 2A | 0.00563258 |
| GSTZ1 | glutathione S-transferase zeta 1 | 0.00562785 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0056262 |
| ATP1A1 | ATPase, Na+/K+ transporting, alpha 1 polypeptide | 0.00561568 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.00559447 |
| GPR137B | G protein-coupled receptor 137B | 0.0055922 |
| NELL2 | NEL-like 2 (chicken) | 0.00556851 |
| BHLHE41 | basic helix-loop-helix family, member e41 | 0.00556833 |
| PRPH | peripherin | 0.00555917 |
| TCF7 | transcription factor 7 (T-cell specific, HMG-box) | 0.00555221 |
| MCL1 | myeloid cell leukemia 1 | 0.0055447 |
| FKBP5 | FK506 binding protein 5 | 0.00553989 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.00551506 |
| C3 | complement component 3 | 0.00551249 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.00550024 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.00547138 |
| PABPC4 | poly(A) binding protein, cytoplasmic 4 (inducible form) | 0.00545475 |
| JUND | jun D proto-oncogene | 0.00543893 |
| RAB29 | RAB29, member RAS oncogene family | 0.00543073 |
| AK4 | adenylate kinase 4 | 0.00542708 |
| DDX11 | DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 | 0.00541834 |
| MT1F | metallothionein 1F | 0.00541391 |
| PALMD | palmdelphin | 0.00539853 |
| ZNF395 | zinc finger protein 395 | 0.00539446 |
| MEIS1 | Meis homeobox 1 | 0.00535575 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.00533517 |
| IGLL1 | immunoglobulin lambda-like polypeptide 1 | 0.00533081 |
| CD58 | CD58 molecule | 0.00532337 |
| GLDC | glycine dehydrogenase (decarboxylating) | 0.00529955 |
| SMAGP | small cell adhesion glycoprotein | 0.00529285 |
| SCPEP1 | serine carboxypeptidase 1 | 0.00529029 |
| DIO1 | deiodinase, iodothyronine, type I | 0.00527466 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.00526946 |
| RRAGD | Ras-related GTP binding D | 0.00526776 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | 0.00525121 |
| NES | nestin | 0.00522815 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 | 0.00521168 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.00521037 |
| PGAP3 | post-GPI attachment to proteins 3 | 0.00519433 |
| SIK1 | salt-inducible kinase 1 | 0.00518755 |
| DSP | desmoplakin | 0.00518521 |
| MAL | mal, T-cell differentiation protein | 0.00517201 |
| BRD2 | bromodomain containing 2 | 0.0051702 |
| BID | BH3 interacting domain death agonist | 0.00516167 |
| MEN1 | multiple endocrine neoplasia I | 0.0051604 |
| CHGB | chromogranin B | 0.00515 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | 0.00513665 |
| LRP4 | low density lipoprotein receptor-related protein 4 | 0.00513453 |
| ADD3 | adducin 3 (gamma) | 0.00508606 |
| BLNK | B-cell linker | 0.00508221 |
| RAG1 | recombination activating gene 1 | 0.00507174 |
| NEFM | neurofilament, medium polypeptide | 0.00506661 |
| VSNL1 | visinin-like 1 | 0.00504767 |
| ETHE1 | ethylmalonic encephalopathy 1 | 0.00504534 |
| BAALC | brain and acute leukemia, cytoplasmic | 0.00503897 |
| TAOK3 | TAO kinase 3 | 0.00502448 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | 0.00502218 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0050204 |
| IFI44L | interferon-induced protein 44-like | 0.00499764 |
| FGF9 | fibroblast growth factor 9 | 0.00498847 |
| CFAP20 | cilia and flagella associated protein 20 | 0.00496991 |
| GSDMB | gasdermin B | 0.00496838 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.00496667 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.00495576 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | 0.00495458 |
| STAG3 | stromal antigen 3 | 0.00494262 |
| HSP90B2P | heat shock protein 90kDa beta (Grp94), member 2, pseudogene | 0.00493066 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.00493015 |
| GPM6B | glycoprotein M6B | 0.00492859 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.00491378 |
| LETMD1 | LETM1 domain containing 1 | 0.00491081 |
| NPDC1 | neural proliferation, differentiation and control, 1 | 0.00490734 |
| CFAP298 | cilia and flagella associated protein 298 | 0.00490483 |
| MAP1A | microtubule-associated protein 1A | 0.00490323 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.00490242 |
| C1ORF115 | chromosome 1 open reading frame 115 | 0.00488485 |
| ATP1A2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide | 0.00488377 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | 0.00487282 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming | 0.00486396 |
| AKIRIN1 | akirin 1 | 0.00485962 |
| DOK5 | docking protein 5 | 0.00485364 |
| FGB | fibrinogen beta chain | 0.00483838 |
| PLLP | plasmolipin | 0.00482794 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.00482646 |
| PEG3 | paternally expressed 3 | 0.00481601 |
| IGBP1 | immunoglobulin (CD79A) binding protein 1 | 0.00480728 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | 0.00480496 |
| SPATA2L | spermatogenesis associated 2-like | 0.00480405 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.00479489 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | 0.00479216 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 | 0.00479189 |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) | 0.00478544 |
| STMN2 | stathmin 2 | 0.00478104 |
| SYT17 | synaptotagmin XVII | 0.00477727 |
| CLDN7 | claudin 7 | 0.00476962 |
| OLFML3 | olfactomedin-like 3 | 0.00475905 |
| ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 | 0.00475744 |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa | 0.00475285 |
| ZIC1 | Zic family member 1 | 0.00474389 |
| HSD11B2 | hydroxysteroid (11-beta) dehydrogenase 2 | 0.00473564 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.00473409 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | 0.00473391 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.00471645 |
| ZFP36 | ZFP36 ring finger protein | 0.00470838 |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 | 0.00470259 |
| WEE1 | WEE1 G2 checkpoint kinase | 0.00470021 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.00469947 |
| PROM1 | prominin 1 | 0.00469635 |
| FAIM | Fas apoptotic inhibitory molecule | 0.00468583 |
| PDE8B | phosphodiesterase 8B | 0.0046802 |
| INA | internexin neuronal intermediate filament protein, alpha | 0.00467281 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 | 0.00466776 |
| ASRGL1 | asparaginase like 1 | 0.00466714 |
| NAV2 | neuron navigator 2 | 0.00466669 |
| HEXB | hexosaminidase B (beta polypeptide) | 0.00466648 |
| WIF1 | WNT inhibitory factor 1 | 0.00466606 |
| SATB2 | SATB homeobox 2 | 0.00464575 |
| NDRG1 | N-myc downstream regulated 1 | 0.00463909 |
| CCN2 | cellular communication network factor 2 | 0.00462893 |
| OGDHL | oxoglutarate dehydrogenase-like | 0.00462746 |
| PMP2 | peripheral myelin protein 2 | 0.00462479 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | 0.00461462 |
| UMOD | uromodulin | 0.00460962 |
| YPEL5 | yippee-like 5 (Drosophila) | 0.00460629 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | 0.00459996 |
| ZMAT3 | zinc finger, matrin-type 3 | 0.00459299 |
| BEX1 | brain expressed, X-linked 1 | 0.0045794 |
| DST | dystonin | 0.00457463 |
| OGFOD1 | 2-oxoglutarate and iron-dependent oxygenase domain containing 1 | 0.00456308 |
| ZNF721 | zinc finger protein 721 | 0.00456029 |
| ITM2C | integral membrane protein 2C | 0.00454415 |
| SERINC3 | serine incorporator 3 | 0.00452487 |
| MBD2 | methyl-CpG binding domain protein 2 | 0.00451895 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.00451454 |
| MMP3 | matrix metallopeptidase 3 | 0.00451315 |
| GGCT | gamma-glutamylcyclotransferase | 0.00451287 |
| GSR | glutathione reductase | 0.0044905 |
| TBC1D4 | TBC1 domain family, member 4 | 0.00448906 |
| PODXL | podocalyxin-like | 0.00448605 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | 0.00447534 |
| PPP1R16B | protein phosphatase 1, regulatory subunit 16B | 0.0044564 |
| CAPN3 | calpain 3, (p94) | 0.00444542 |
| PCOLCE | procollagen C-endopeptidase enhancer | 0.00444354 |
| GAD1 | glutamate decarboxylase 1 (brain, 67kDa) | 0.0044363 |
| NFIL3 | nuclear factor, interleukin 3 regulated | 0.00443463 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | 0.00443265 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.00442694 |
| SEZ6L2 | seizure related 6 homolog (mouse)-like 2 | 0.0044226 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.00441982 |
| LEFTY1 | left-right determination factor 1 | 0.00441961 |
| AOC1 | amine oxidase, copper containing 1 | 0.00441783 |
| CSNK2A2 | casein kinase 2, alpha prime polypeptide | 0.00441723 |
| TERT | telomerase reverse transcriptase | 0.00440674 |
| IK | IK cytokine, down-regulator of HLA II | 0.00440096 |
| TSPAN3 | tetraspanin 3 | 0.0043996 |
| NDRG2 | NDRG family member 2 | 0.00439951 |
| FGF1 | fibroblast growth factor 1 (acidic) | 0.00439537 |
| TMEM176B | transmembrane protein 176B | 0.00439426 |
| FABP1 | fatty acid binding protein 1, liver | 0.00439426 |
| MCAM | melanoma cell adhesion molecule | 0.00438564 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 | 0.00438366 |
| IER3 | immediate early response 3 | 0.0043786 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.00437218 |
| PNPLA3 | patatin-like phospholipase domain containing 3 | 0.00437004 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | 0.00436837 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase | 0.00436682 |
| BCAS1 | breast carcinoma amplified sequence 1 | 0.00436446 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | -0.0112488 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0112476 |
| TPSAB1 | tryptase alpha/beta 1 | -0.0107191 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.0105377 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -0.0100046 |
| FSTL1 | follistatin-like 1 | -0.00893252 |
| PHACTR2 | phosphatase and actin regulator 2 | -0.00885128 |
| SC5D | sterol-C5-desaturase | -0.00870494 |
| S100P | S100 calcium binding protein P | -0.008244 |
| CADM1 | cell adhesion molecule 1 | -0.007905 |
| KRT17 | keratin 17, type I | -0.00790186 |
| CCND1 | cyclin D1 | -0.00778374 |
| TUBB6 | tubulin, beta 6 class V | -0.00774845 |
| CPA3 | carboxypeptidase A3 (mast cell) | -0.00769443 |
| TMEM126B | transmembrane protein 126B | -0.00764103 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | -0.00753164 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.00747001 |
| ANXA3 | annexin A3 | -0.0074608 |
| YAP1 | Yes-associated protein 1 | -0.0073764 |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist | -0.0072268 |
| TAGLN | transgelin | -0.00721716 |
| CPB1 | carboxypeptidase B1 (tissue) | -0.00721216 |
| MAP7 | microtubule-associated protein 7 | -0.00720778 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | -0.00708952 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | -0.00707965 |
| MAGED1 | melanoma antigen family D1 | -0.00699429 |
| NMU | neuromedin U | -0.00690763 |
| GPX3 | glutathione peroxidase 3 | -0.00685733 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.00679016 |
| EFNB2 | ephrin-B2 | -0.00674797 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase | -0.00664511 |
| GLS | glutaminase | -0.00657411 |
| TRAPPC4 | trafficking protein particle complex 4 | -0.006568 |
| JCHAIN | joining chain of multimeric IgA and IgM | -0.00651069 |
| CCND2 | cyclin D2 | -0.00646881 |
| CD320 | CD320 molecule | -0.00636513 |
| BAD | BCL2-associated agonist of cell death | -0.00624214 |
| MALL | mal, T-cell differentiation protein-like | -0.00623519 |
| P2RY14 | purinergic receptor P2Y, G-protein coupled, 14 | -0.00622082 |
| ADRB2 | adrenoceptor beta 2, surface | -0.00620266 |
| NPTX2 | neuronal pentraxin II | -0.00617783 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | -0.00616924 |
| ABHD17A | abhydrolase domain containing 17A | -0.00616328 |
| NPM3 | nucleophosmin/nucleoplasmin 3 | -0.00614218 |
| CDKN3 | cyclin-dependent kinase inhibitor 3 | -0.00613526 |
| RAB32 | RAB32, member RAS oncogene family | -0.00605763 |
| RXRA | retinoid X receptor, alpha | -0.0060499 |
| SIDT2 | SID1 transmembrane family, member 2 | -0.00601882 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.00599621 |
| ANKRD49 | ankyrin repeat domain 49 | -0.00599478 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.00599406 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | -0.00598198 |
| TAX1BP3 | Tax1 (human T-cell leukemia virus type I) binding protein 3 | -0.00596098 |
| TGM2 | transglutaminase 2 | -0.00595633 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.00595161 |
| H2AX | H2A.X variant histone | -0.00593556 |
| COMP | cartilage oligomeric matrix protein | -0.00592647 |
| FBN2 | fibrillin 2 | -0.00591877 |
| ATP11B | ATPase, class VI, type 11B | -0.00588692 |
| IL18 | interleukin 18 | -0.00586551 |
| NADK | NAD kinase | -0.00583792 |
| MTMR2 | myotubularin related protein 2 | -0.00583779 |
| PAEP | progestagen-associated endometrial protein | -0.00581901 |
| CLEC2B | C-type lectin domain family 2, member B | -0.00579787 |
| TMEM135 | transmembrane protein 135 | -0.00575114 |
| CAV2 | caveolin 2 | -0.00574743 |
| NXN | nucleoredoxin | -0.00573732 |
| S100A2 | S100 calcium binding protein A2 | -0.00572516 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.00572273 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.00570339 |
| AGR2 | anterior gradient 2 | -0.00569852 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | -0.00567988 |
| LTBP2 | latent transforming growth factor beta binding protein 2 | -0.00567553 |
| THAP12 | THAP domain containing 12 | -0.00564023 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.0056297 |
| FBLN1 | fibulin 1 | -0.00562173 |
| TXNDC9 | thioredoxin domain containing 9 | -0.00561113 |
| CCL2 | chemokine (C-C motif) ligand 2 | -0.00560607 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | -0.00556047 |
| SUB1 | SUB1 homolog (S. cerevisiae) | -0.00555604 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0054941 |
| MICU2 | mitochondrial calcium uptake 2 | -0.00548306 |
| GSTT1 | glutathione S-transferase theta 1 | -0.00547438 |
| SH3BGRL | SH3 domain binding glutamate-rich protein like | -0.00545116 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | -0.00545108 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | -0.00543798 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.00543166 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.00542615 |
| SMAD7 | SMAD family member 7 | -0.00542554 |
| GNG10 | guanine nucleotide binding protein (G protein), gamma 10 | -0.00539414 |
| PRKCZ | protein kinase C, zeta | -0.00536943 |
| MICALL1 | MICAL-like 1 | -0.00536606 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | -0.0053611 |
| SNX7 | sorting nexin 7 | -0.00535593 |
| AMD1 | adenosylmethionine decarboxylase 1 | -0.00535044 |
| G6PD | glucose-6-phosphate dehydrogenase | -0.00534906 |
| PEX3 | peroxisomal biogenesis factor 3 | -0.005348 |
| RCAN2 | regulator of calcineurin 2 | -0.00531276 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.00530854 |
| MET | MET proto-oncogene, receptor tyrosine kinase | -0.00530762 |
| PMP22 | peripheral myelin protein 22 | -0.00530261 |
| COL6A2 | collagen, type VI, alpha 2 | -0.00527578 |
| DVL1 | dishevelled segment polarity protein 1 | -0.00527505 |
| SLC38A6 | solute carrier family 38, member 6 | -0.00527183 |
| GTPBP8 | GTP-binding protein 8 (putative) | -0.00526324 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | -0.00525738 |
| PPAP2A | phosphatidic acid phosphatase type 2A | -0.00524787 |
| NSMF | NMDA receptor synaptonuclear signaling and neuronal migration factor | -0.00524706 |
| HES1 | hes family bHLH transcription factor 1 | -0.00522103 |
| CYTH1 | cytohesin 1 | -0.00520296 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | -0.00516641 |
| PGC | progastricsin (pepsinogen C) | -0.005097 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.00508798 |
| HAUS3 | HAUS augmin-like complex, subunit 3 | -0.00508616 |
| LTF | lactotransferrin | -0.00507362 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.00507104 |
| REXO2 | RNA exonuclease 2 | -0.00506168 |
| RBM7 | RNA binding motif protein 7 | -0.00505652 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.00504966 |
| SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 | -0.00504773 |
| CLGN | calmegin | -0.00500713 |
| SIK3 | SIK family kinase 3 | -0.00498287 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.00498107 |
| EED | embryonic ectoderm development | -0.00497548 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | -0.00497182 |
| NOTCH2 | notch 2 | -0.00496317 |
| CCL8 | chemokine (C-C motif) ligand 8 | -0.00495998 |
| MED17 | mediator complex subunit 17 | -0.00495841 |
| MAEA | macrophage erythroblast attacher | -0.00494699 |
| UBE2S | ubiquitin-conjugating enzyme E2S | -0.00493721 |
| CDK8 | cyclin-dependent kinase 8 | -0.00492999 |
| COMMD8 | COMM domain containing 8 | -0.00492449 |
| CAMKK2 | calcium/calmodulin-dependent protein kinase kinase 2, beta | -0.00489021 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 | -0.00488443 |
| TGFB1 | transforming growth factor, beta 1 | -0.00488108 |
| PMM2 | phosphomannomutase 2 | -0.00486587 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.00486058 |
| BCL7B | B-cell CLL/lymphoma 7B | -0.00484798 |
| NNMT | nicotinamide N-methyltransferase | -0.0048472 |
| ELN | elastin | -0.00483992 |
| NELL1 | NEL-like 1 (chicken) | -0.00482352 |
| RAB38 | RAB38, member RAS oncogene family | -0.00482178 |
| PER3 | period circadian clock 3 | -0.00481515 |
| ITM2A | integral membrane protein 2A | -0.00480796 |
| SOAT1 | sterol O-acyltransferase 1 | -0.00480409 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.00479955 |
| MMP2 | matrix metallopeptidase 2 | -0.00479746 |
| COL2A1 | collagen, type II, alpha 1 | -0.00479507 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.00478627 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.00478237 |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa | -0.00477453 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.00477364 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.00476978 |
| LRP5 | low density lipoprotein receptor-related protein 5 | -0.00476887 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.00476708 |
| RP2 | retinitis pigmentosa 2 (X-linked recessive) | -0.00476659 |
| MN1 | meningioma (disrupted in balanced translocation) 1 | -0.00476514 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.00474963 |
| SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) | -0.00474561 |
| DBF4 | DBF4 zinc finger | -0.00473621 |
| RASA1 | RAS p21 protein activator (GTPase activating protein) 1 | -0.00473353 |
| RAPSN | receptor-associated protein of the synapse | -0.00471336 |
| MARCHF1 | membrane associated ring-CH-type finger 1 | -0.00469734 |
| TTC37 | tetratricopeptide repeat domain 37 | -0.00469544 |
| IDH3A | isocitrate dehydrogenase 3 (NAD+) alpha | -0.00466735 |
| RPS5 | ribosomal protein S5 | -0.00465399 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | -0.0046309 |
| FDX1 | ferredoxin 1 | -0.00462471 |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic | -0.00461006 |
| COMMD10 | COMM domain containing 10 | -0.00460224 |
| TMEM165 | transmembrane protein 165 | -0.00459326 |
| ATG4B | autophagy related 4B, cysteine peptidase | -0.00458784 |
| PTS | 6-pyruvoyltetrahydropterin synthase | -0.0045639 |
| UBE2D1 | ubiquitin-conjugating enzyme E2D 1 | -0.00456297 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.0045629 |
| NDNF | neuron-derived neurotrophic factor | -0.00455561 |
| PMF1 | polyamine-modulated factor 1 | -0.00455109 |
| TLE4 | transducin-like enhancer of split 4 | -0.00453456 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 | -0.00451344 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -0.0045058 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | -0.00450002 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | -0.00448941 |
| COQ2 | coenzyme Q2 4-hydroxybenzoate polyprenyltransferase | -0.00447821 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.00447166 |
| KCTD5 | potassium channel tetramerization domain containing 5 | -0.00446198 |
| CREBZF | CREB/ATF bZIP transcription factor | -0.00446191 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.00445272 |
| RBPMS | RNA binding protein with multiple splicing | -0.00444707 |
| SOCS1 | suppressor of cytokine signaling 1 | -0.00443499 |
| FGL2 | fibrinogen-like 2 | -0.00442406 |
| DSE | dermatan sulfate epimerase | -0.00441304 |
| ITGA8 | integrin, alpha 8 | -0.0044091 |
| WDR61 | WD repeat domain 61 | -0.00440272 |
| PRSS3 | protease, serine, 3 | -0.00440102 |
| HYOU1 | hypoxia up-regulated 1 | -0.00439771 |
| C1QA | complement component 1, q subcomponent, A chain | -0.0043958 |
| PLK2 | polo-like kinase 2 | -0.00439266 |
| DCHS1 | dachsous cadherin-related 1 | -0.00437372 |
| BCAP29 | B-cell receptor-associated protein 29 | -0.00437286 |
| MED28 | mediator complex subunit 28 | -0.00437118 |
| POSTN | periostin, osteoblast specific factor | -0.00437025 |
| TACC3 | transforming, acidic coiled-coil containing protein 3 | -0.00437006 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | -0.00436199 |
| MRPS12 | mitochondrial ribosomal protein S12 | -0.00435406 |
| RHOD | ras homolog family member D | -0.00435163 |
| PDGFC | platelet derived growth factor C | -0.00434906 |
| UBE2M | ubiquitin-conjugating enzyme E2M | -0.0043434 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | -0.0043431 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | -0.0043394 |
| RNF6 | ring finger protein (C3H2C3 type) 6 | -0.00433822 |
| SRPRA | SRP receptor subunit alpha | -0.00433086 |
| HSF2 | heat shock transcription factor 2 | -0.00433046 |
| APOBEC3G | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G | -0.00432853 |
| CCL4 | chemokine (C-C motif) ligand 4 | -0.00432417 |
| OGFOD3 | 2-oxoglutarate and iron-dependent oxygenase domain containing 3 | -0.00432009 |
| CCNB1 | cyclin B1 | -0.00431505 |
| RIT1 | Ras-like without CAAX 1 | -0.00431369 |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 | -0.00430361 |
| CENPU | centromere protein U | -0.00430106 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | -0.00429198 |
| CD151 | CD151 molecule (Raph blood group) | -0.00428408 |
| MTCL1 | microtubule crosslinking factor 1 | -0.00427971 |
| TSPAN4 | tetraspanin 4 | -0.00427058 |
| SDF4 | stromal cell derived factor 4 | -0.00427053 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.00426834 |
| SNX3 | sorting nexin 3 | -0.00426167 |
| MRPS2 | mitochondrial ribosomal protein S2 | -0.0042611 |
| ATP5MG | ATP synthase membrane subunit g | -0.00425148 |
| ACAD8 | acyl-CoA dehydrogenase family, member 8 | -0.00424202 |
| RANBP1 | RAN binding protein 1 | -0.00423773 |
| PKN2 | protein kinase N2 | -0.00422364 |
| NOL11 | nucleolar protein 11 | -0.0042193 |
| COPS4 | COP9 signalosome subunit 4 | -0.00419909 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.00419754 |
| LYZ | lysozyme | -0.00419633 |
| KAT5 | K(lysine) acetyltransferase 5 | -0.00419348 |
| TYMP | thymidine phosphorylase | -0.00419272 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.00418103 |
| CAVIN1 | caveolae associated protein 1 | -0.00417822 |
| MPZL2 | myelin protein zero-like 2 | -0.00417784 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | -0.00417202 |
| SOCS5 | suppressor of cytokine signaling 5 | -0.00415723 |
| EDRF1 | erythroid differentiation regulatory factor 1 | -0.00415406 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.00414798 |
| TRIM28 | tripartite motif containing 28 | -0.00414794 |
| NUDT11 | nudix (nucleoside diphosphate linked moiety X)-type motif 11 | -0.00414292 |
| TFAM | transcription factor A, mitochondrial | -0.00414091 |
| INTS6 | integrator complex subunit 6 | -0.00413693 |
| TLK2 | tousled-like kinase 2 | -0.00412456 |
