PPP1CA Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description protein phosphatase 1, catalytic subunit, alpha isozyme|The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 5499)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/MORF_PPP1CA
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Genes

169 co-expressed genes for PPP1CA from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
AP1B1 adaptor-related protein complex 1, beta 1 subunit
AP2M1 adaptor-related protein complex 2, mu 1 subunit
AP2S1 adaptor-related protein complex 2, sigma 1 subunit
ARF3 ADP-ribosylation factor 3
ARF5 ADP-ribosylation factor 5
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1
ATP5H ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d
ATP5J2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1
BANF1 barrier to autointegration factor 1
BCAP31 B-cell receptor-associated protein 31
BLOC1S1 biogenesis of lysosomal organelles complex-1, subunit 1
BUD31 BUD31 homolog (S. cerevisiae)
C21ORF33 chromosome 21 open reading frame 33
C9ORF16 chromosome 9 open reading frame 16
CANX calnexin
CBX3 chromobox homolog 3
CCT2 chaperonin containing TCP1, subunit 2 (beta)
CCT7 chaperonin containing TCP1, subunit 7 (eta)
CDC123 cell division cycle 123
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase
CFDP1 craniofacial development protein 1
CLTA clathrin, light chain A
CNBP CCHC-type zinc finger, nucleic acid binding protein
CNIH1 cornichon family AMPA receptor auxiliary protein 1
COIL coilin
COPE coatomer protein complex, subunit epsilon
COPS5 COP9 signalosome subunit 5
COX4I1 cytochrome c oxidase subunit IV isoform 1
COX5A cytochrome c oxidase subunit Va
COX5B cytochrome c oxidase subunit Vb
COX6A1 cytochrome c oxidase subunit VIa polypeptide 1
COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous)
COX6C cytochrome c oxidase subunit VIc
COX7A2L cytochrome c oxidase subunit VIIa polypeptide 2 like
CSNK2B casein kinase 2, beta polypeptide
CTBP1 C-terminal binding protein 1
CTCF CCCTC-binding factor (zinc finger protein)
CYC1 cytochrome c-1
DAP death-associated protein
DCTN2 dynactin 2 (p50)
DDX49 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
DNPEP aspartyl aminopeptidase
DRG1 developmentally regulated GTP binding protein 1
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
EIF3C eukaryotic translation initiation factor 3, subunit C
EIF3K eukaryotic translation initiation factor 3, subunit K
EIF4E2 eukaryotic translation initiation factor 4E family member 2
EIF4H eukaryotic translation initiation factor 4H
ENSA endosulfine alpha
ERP29 endoplasmic reticulum protein 29
ETFA electron-transfer-flavoprotein, alpha polypeptide
FAM120A family with sequence similarity 120A
FIBP fibroblast growth factor (acidic) intracellular binding protein
GABARAPL2 GABA(A) receptor-associated protein-like 2
GANAB glucosidase, alpha; neutral AB
GGCT gamma-glutamylcyclotransferase
H2AFZ H2A histone family, member Z
HARS2 histidyl-tRNA synthetase 2, mitochondrial
HDAC1 histone deacetylase 1
HDGF hepatoma-derived growth factor
HMGN1 high mobility group nucleosome binding domain 1
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2)
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1
HSBP1 heat shock factor binding protein 1
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPD1 heat shock 60kDa protein 1 (chaperonin)
JTB jumping translocation breakpoint
KARS lysyl-tRNA synthetase
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KIAA0101 KIAA0101
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LYPLA1 lysophospholipase I
MBD4 methyl-CpG binding domain protein 4
MBTPS1 membrane-bound transcription factor peptidase, site 1
MDH1 malate dehydrogenase 1, NAD (soluble)
MRPL9 mitochondrial ribosomal protein L9
MTDH metadherin
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
MYL12B myosin, light chain 12B, regulatory
NDUFA1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
NEDD8 neural precursor cell expressed, developmentally down-regulated 8
NONO non-POU domain containing, octamer-binding
PARK7 parkinson protein 7
PDAP1 PDGFA associated protein 1
PDCD6 programmed cell death 6
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit
POLR2G polymerase (RNA) II (DNA directed) polypeptide G
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPP1R7 protein phosphatase 1, regulatory subunit 7
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PPP6C protein phosphatase 6, catalytic subunit
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRMT1 protein arginine methyltransferase 1
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
PUF60 poly-U binding splicing factor 60KDa
RAD21 RAD21 homolog (S. pombe)
RAD23B RAD23 homolog B (S. cerevisiae)
RALY RALY heterogeneous nuclear ribonucleoprotein
RAN RAN, member RAS oncogene family
RBMX RNA binding motif protein, X-linked
RER1 retention in endoplasmic reticulum sorting receptor 1
RNF6 ring finger protein (C3H2C3 type) 6
RPL36AL ribosomal protein L36a-like
SET SET nuclear proto-oncogene
SF3B2 splicing factor 3b, subunit 2, 145kDa
SHFM1 split hand/foot malformation (ectrodactyly) type 1
SKP1 S-phase kinase-associated protein 1
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
SMG7 SMG7 nonsense mediated mRNA decay factor
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa
SNRPE small nuclear ribonucleoprotein polypeptide E
SNRPG small nuclear ribonucleoprotein polypeptide G
SOD1 superoxide dismutase 1, soluble
SRP9 signal recognition particle 9kDa
SRSF3 serine/arginine-rich splicing factor 3
SRSF9 serine/arginine-rich splicing factor 9
SSR2 signal sequence receptor, beta (translocon-associated protein beta)
STARD7 StAR-related lipid transfer (START) domain containing 7
STOML2 stomatin (EPB72)-like 2
SUMO1 small ubiquitin-like modifier 1
SUMO2 small ubiquitin-like modifier 2
SUMO3 small ubiquitin-like modifier 3
SYPL1 synaptophysin-like 1
TAF11 TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa
TBCA tubulin folding cofactor A
TCEB1 transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
TCEB2 transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)
TECR trans-2,3-enoyl-CoA reductase
TMBIM6 transmembrane BAX inhibitor motif containing 6
TMED2 transmembrane emp24 domain trafficking protein 2
TMEM147 transmembrane protein 147
TRIM28 tripartite motif containing 28
TUFM Tu translation elongation factor, mitochondrial
TUG1 taurine up-regulated 1 (non-protein coding)
UBA1 ubiquitin-like modifier activating enzyme 1
UBAP2L ubiquitin associated protein 2-like
UBE4A ubiquitination factor E4A
UQCRB ubiquinol-cytochrome c reductase binding protein
URM1 ubiquitin related modifier 1
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast)
VCP valosin containing protein
VTI1B vesicle transport through interaction with t-SNAREs 1B
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
YY1 YY1 transcription factor