PPP1CC Gene Set

Dataset DEPOD Substrates of Phosphatases
Category physical interactions
Type phosphatase
Description protein phosphatase 1, catalytic subunit, gamma isozyme|The protein encoded by this gene belongs to the protein phosphatase family, PP1 subfamily. PP1 is an ubiquitous serine/threonine phosphatase that regulates many cellular processes, including cell division. It is expressed in mammalian cells as three closely related isoforms, alpha, beta/delta and gamma, which have distinct localization patterns. This gene encodes the gamma isozyme. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011] (NCBI Entrez Gene Database, 5501)
External Link http://www.koehn.embl.de/depod/showp.php?gene=PPP1CC
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Genes

37 substrates of the phosphatase PPP1CC from the curated DEPOD Substrates of Phosphatases dataset.

Symbol Name
AHCYL1 adenosylhomocysteinase-like 1
AKT1 v-akt murine thymoma viral oncogene homolog 1
ATM ATM serine/threonine kinase
AURKA aurora kinase A
AXIN1 axin 1
BAD BCL2-associated agonist of cell death
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CASP2 caspase 2, apoptosis-related cysteine peptidase
CDC25C cell division cycle 25C
CEP250 centrosomal protein 250kDa
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
H2AFX H2A histone family, member X
HIST1H3A histone cluster 1, H3a
IKZF1 IKAROS family zinc finger 1 (Ikaros)
MAPT microtubule-associated protein tau
MBP myelin basic protein
NCOR1 nuclear receptor corepressor 1
NOS3 nitric oxide synthase 3 (endothelial cell)
POLD3 polymerase (DNA-directed), delta 3, accessory subunit
PRKCA protein kinase C, alpha
PRKCD protein kinase C, delta
PRKD1 protein kinase D1
PTK2 protein tyrosine kinase 2
PTPN7 protein tyrosine phosphatase, non-receptor type 7
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RB1 retinoblastoma 1
RYR1 ryanodine receptor 1 (skeletal)
SMO smoothened, frizzled class receptor
STK3 serine/threonine kinase 3
STK4 serine/threonine kinase 4
TNNI3 troponin I type 3 (cardiac)
TNNT2 troponin T type 2 (cardiac)
TP53 tumor protein p53