PPP2CA Gene Set

Dataset DEPOD Substrates of Phosphatases
Category physical interactions
Type phosphatase
Description protein phosphatase 2, catalytic subunit, alpha isozyme|This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes an alpha isoform of the catalytic subunit. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 5515)
External Link http://www.koehn.embl.de/depod/showp.php?gene=PPP2CA
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Genes

87 substrates of the phosphatase PPP2CA from the curated DEPOD Substrates of Phosphatases dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT3 v-akt murine thymoma viral oncogene homolog 3
ATM ATM serine/threonine kinase
AXIN1 axin 1
BAD BCL2-associated agonist of cell death
BAX BCL2-associated X protein
BCAR1 breast cancer anti-estrogen resistance 1
BCL2 B-cell CLL/lymphoma 2
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CAMK1 calcium/calmodulin-dependent protein kinase I
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CAMK4 calcium/calmodulin-dependent protein kinase IV
CARD11 caspase recruitment domain family, member 11
CASP3 caspase 3, apoptosis-related cysteine peptidase
CDK1 cyclin-dependent kinase 1
CDK2 cyclin-dependent kinase 2
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CDK9 cyclin-dependent kinase 9
CHEK1 checkpoint kinase 1
CHEK2 checkpoint kinase 2
CHUK conserved helix-loop-helix ubiquitous kinase
CREB1 cAMP responsive element binding protein 1
EEF2 eukaryotic translation elongation factor 2
ELF1 E74-like factor 1 (ets domain transcription factor)
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GOLGA2 golgin A2
H2AFX H2A histone family, member X
HDAC7 histone deacetylase 7
HIST1H3A histone cluster 1, H3a
HSPB1 heat shock 27kDa protein 1
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IL6ST interleukin 6 signal transducer
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
KRT8 keratin 8, type II
LOC102724652 alpha-crystallin A chain
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K4 mitogen-activated protein kinase kinase 4
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK8 mitogen-activated protein kinase 8
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MAPT microtubule-associated protein tau
MBP myelin basic protein
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MYC v-myc avian myelocytomatosis viral oncogene homolog
NEFH neurofilament, heavy polypeptide
PACS1 phosphofurin acidic cluster sorting protein 1
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PLK1 polo-like kinase 1
PNCK pregnancy up-regulated nonubiquitous CaM kinase
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKCA protein kinase C, alpha
PRKCB protein kinase C, beta
PRKCD protein kinase C, delta
PRKCI protein kinase C, iota
PRKD1 protein kinase D1
PRKG1 protein kinase, cGMP-dependent, type I
PXN paxillin
RACGAP1 Rac GTPase activating protein 1
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RBL1 retinoblastoma-like 1
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RHO rhodopsin
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
SMAD1 SMAD family member 1
SMAD3 SMAD family member 3
SMO smoothened, frizzled class receptor
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SPHK1 sphingosine kinase 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STK3 serine/threonine kinase 3
STK4 serine/threonine kinase 4
TP53 tumor protein p53
TRAF2 TNF receptor-associated factor 2
VASP vasodilator-stimulated phosphoprotein
VIM vimentin