PPP2CA Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description protein phosphatase 2, catalytic subunit, alpha isozyme|This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes an alpha isoform of the catalytic subunit. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 5515)
External Link https://ncbi.nlm.nih.gov/gene/5515
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Genes

499 genes differentially expressed following the PPP2CA gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
HOPX HOP homeobox 0.0197431
CXCL13 chemokine (C-X-C motif) ligand 13 0.0170462
MYBPC1 myosin binding protein C, slow type 0.0162306
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.0153624
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 0.0138201
USP18 ubiquitin specific peptidase 18 0.013564
MBOAT7 membrane bound O-acyltransferase domain containing 7 0.0134549
IL32 interleukin 32 0.013365
ALOX5AP arachidonate 5-lipoxygenase-activating protein 0.0126528
KRT17 keratin 17, type I 0.0122775
SIRT3 sirtuin 3 0.0122764
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 0.0122159
IFI44L interferon-induced protein 44-like 0.0119115
DSP desmoplakin 0.0114832
MKNK1 MAP kinase interacting serine/threonine kinase 1 0.0111748
CHN1 chimerin 1 0.0108922
IER2 immediate early response 2 0.0107678
ABLIM1 actin binding LIM protein 1 0.0107237
IRS2 insulin receptor substrate 2 0.010646
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.0105625
GNLY granulysin 0.0103803
C1QA complement component 1, q subcomponent, A chain 0.0103716
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 0.0103301
COL4A5 collagen, type IV, alpha 5 0.0102743
CHI3L2 chitinase 3-like 2 0.0102504
CST7 cystatin F (leukocystatin) 0.0102425
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 0.0101723
RHOBTB3 Rho-related BTB domain containing 3 0.0101334
KRT14 keratin 14, type I 0.0100145
UXT ubiquitously-expressed, prefoldin-like chaperone 0.00994813
CKM creatine kinase, muscle 0.00992671
C1S complement component 1, s subcomponent 0.00991541
WASHC4 WASH complex subunit 4 0.00988545
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 0.00985536
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 0.00978052
PDHX pyruvate dehydrogenase complex, component X 0.00976883
TSC22D1 TSC22 domain family, member 1 0.00974827
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.00973657
MMP12 matrix metallopeptidase 12 0.00966664
YBX3 Y box binding protein 3 0.00966391
TLK2 tousled-like kinase 2 0.00957065
FNDC3B fibronectin type III domain containing 3B 0.00952843
CCL4 chemokine (C-C motif) ligand 4 0.00952222
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 0.00949913
IFITM1 interferon induced transmembrane protein 1 0.00946545
CPA3 carboxypeptidase A3 (mast cell) 0.00944402
ACTA1 actin, alpha 1, skeletal muscle 0.00920262
KLHL41 kelch-like family member 41 0.00917702
RGS13 regulator of G-protein signaling 13 0.00916477
NES nestin 0.00910746
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 0.0090527
NIBAN1 niban apoptosis regulator 1 0.00892414
GBP2 guanylate binding protein 2, interferon-inducible 0.00889237
KRT16 keratin 16, type I 0.00887363
MYL2 myosin, light chain 2, regulatory, cardiac, slow 0.00883634
HMG20B high mobility group 20B 0.00883411
EZR ezrin 0.00878999
ACTC1 actin, alpha, cardiac muscle 1 0.0087896
KRT1 keratin 1, type II 0.00876422
NKG7 natural killer cell granule protein 7 0.00867514
PMP22 peripheral myelin protein 22 0.00861193
HLA-B major histocompatibility complex, class I, B 0.00860276
IL2RB interleukin 2 receptor, beta 0.00857889
LYPD3 LY6/PLAUR domain containing 3 0.00857325
TTN titin 0.00854349
AQP3 aquaporin 3 (Gill blood group) 0.00850069
ACTB actin, beta 0.00849502
TENT5A terminal nucleotidyltransferase 5A 0.00847302
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 0.00843577
CXCR4 chemokine (C-X-C motif) receptor 4 0.00841655
PTCH1 patched 1 0.00841477
FOXO1 forkhead box O1 0.00836514
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 0.00835938
FKBP11 FK506 binding protein 11, 19 kDa 0.00835272
ZDHHC6 zinc finger, DHHC-type containing 6 0.00830709
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 0.0082702
MS4A1 membrane-spanning 4-domains, subfamily A, member 1 0.00820835
JUNB jun B proto-oncogene 0.00820768
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 0.00815577
NMT2 N-myristoyltransferase 2 0.00815536
GBP1 guanylate binding protein 1, interferon-inducible 0.00814815
CCL5 chemokine (C-C motif) ligand 5 0.00812938
TGM2 transglutaminase 2 0.00810222
MXI1 MAX interactor 1, dimerization protein 0.00810089
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1 0.00809108
TPM2 tropomyosin 2 (beta) 0.00808148
CD69 CD69 molecule 0.00804203
PRAME preferentially expressed antigen in melanoma 0.00798359
SLN sarcolipin 0.00796087
PKP1 plakophilin 1 0.00793871
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 0.00792428
FBXO11 F-box protein 11 0.0079135
NIT1 nitrilase 1 0.00788198
MYH3 myosin, heavy chain 3, skeletal muscle, embryonic 0.0078614
DHRS11 dehydrogenase/reductase (SDR family) member 11 0.00783907
PACSIN2 protein kinase C and casein kinase substrate in neurons 2 0.00783151
BSG basigin (Ok blood group) 0.00782172
ZNF750 zinc finger protein 750 0.00779767
MLPH melanophilin 0.00777405
PPIC peptidylprolyl isomerase C (cyclophilin C) 0.00774966
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.00774299
DMPK dystrophia myotonica-protein kinase 0.00773115
MYL1 myosin, light chain 1, alkali; skeletal, fast 0.00772514
AIM2 absent in melanoma 2 0.00769939
CLEC2D C-type lectin domain family 2, member D 0.00769471
CXCL10 chemokine (C-X-C motif) ligand 10 0.00768414
MAP3K7CL MAP3K7 C-terminal like 0.00766081
TARP TCR gamma alternate reading frame protein 0.00765912
TBX3 T-box 3 0.00765095
HLA-F major histocompatibility complex, class I, F 0.00764564
MSX1 msh homeobox 1 0.00762289
STX4 syntaxin 4 0.00760526
RHOA ras homolog family member A 0.00754156
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.00753391
AVPI1 arginine vasopressin-induced 1 0.00753358
OASL 2'-5'-oligoadenylate synthetase-like 0.00751083
LPP LIM domain containing preferred translocation partner in lipoma 0.00750445
MYOF myoferlin 0.00747732
IFITM3 interferon induced transmembrane protein 3 0.00746605
AMMECR1 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 0.00745853
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 0.00743302
HLA-A major histocompatibility complex, class I, A 0.00743046
C1QB complement component 1, q subcomponent, B chain 0.00742654
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 0.00741548
CLCN3 chloride channel, voltage-sensitive 3 0.00739263
AKAP8 A kinase (PRKA) anchor protein 8 0.00735372
FOSL2 FOS-like antigen 2 0.00734616
S100A2 S100 calcium binding protein A2 0.00734125
RUNX3 runt-related transcription factor 3 0.00733235
ISG15 ISG15 ubiquitin-like modifier 0.00733115
RGCC regulator of cell cycle 0.007322
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 0.00726179
LCK LCK proto-oncogene, Src family tyrosine kinase 0.00724182
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 0.00723983
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) 0.00722138
BHLHE40 basic helix-loop-helix family, member e40 0.00721975
LGALS8 lectin, galactoside-binding, soluble, 8 0.00720309
LY6D lymphocyte antigen 6 complex, locus D 0.00718535
CTSB cathepsin B 0.00717707
ERBIN erbb2 interacting protein 0.0071694
XCL1 chemokine (C motif) ligand 1 0.00714841
IFI27 interferon, alpha-inducible protein 27 0.00714199
MTCL1 microtubule crosslinking factor 1 0.00711367
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit 0.00711293
GCLC glutamate-cysteine ligase, catalytic subunit 0.0070925
PHF11 PHD finger protein 11 0.00708386
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX) 0.00705693
COL5A2 collagen, type V, alpha 2 0.00705629
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 0.00704621
CLCA2 chloride channel accessory 2 0.0070093
EGR2 early growth response 2 0.00700711
TBL1X transducin (beta)-like 1X-linked 0.00700546
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 0.0070041
SFTPB surfactant protein B 0.00700377
NLRP2 NLR family, pyrin domain containing 2 0.0069993
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1 0.0069955
G6PD glucose-6-phosphate dehydrogenase 0.00698153
S100A7 S100 calcium binding protein A7 0.00698124
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 0.00697413
NXT2 nuclear transport factor 2-like export factor 2 0.00697318
RNF19B ring finger protein 19B 0.00697305
TMEM100 transmembrane protein 100 0.00697041
DRAM1 DNA-damage regulated autophagy modulator 1 0.00696974
ELP1 elongator acetyltransferase complex subunit 1 0.00695632
DUSP2 dual specificity phosphatase 2 0.00691491
KRT6A keratin 6A, type II 0.00690543
TUBB2A tubulin, beta 2A class IIa 0.00688508
GSPT1 G1 to S phase transition 1 0.00688494
PRF1 perforin 1 (pore forming protein) 0.00685633
TNNC1 troponin C type 1 (slow) 0.0068523
PDE4D phosphodiesterase 4D, cAMP-specific 0.00685089
ISG20 interferon stimulated exonuclease gene 20kDa 0.00684609
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.00683069
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 0.00681988
GIMAP4 GTPase, IMAP family member 4 0.00681649
VEGFA vascular endothelial growth factor A 0.00681428
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 0.00680929
TNNC2 troponin C type 2 (fast) 0.00680753
A2M alpha-2-macroglobulin 0.00680317
SMPX small muscle protein, X-linked 0.00679015
BCL2L13 BCL2-like 13 (apoptosis facilitator) 0.00679014
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 0.00677941
DSTN destrin (actin depolymerizing factor) 0.0067662
MET MET proto-oncogene, receptor tyrosine kinase 0.00674093
KCTD13 potassium channel tetramerization domain containing 13 0.0067342
MB myoglobin 0.00673208
SCRG1 stimulator of chondrogenesis 1 0.00672908
NCSTN nicastrin 0.00671123
ZNF518A zinc finger protein 518A 0.00670997
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase 0.00669398
CH25H cholesterol 25-hydroxylase 0.00667875
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 0.00667558
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 0.00667338
CNR1 cannabinoid receptor 1 (brain) 0.00667225
GSAP gamma-secretase activating protein 0.00665825
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 0.006649
CDK8 cyclin-dependent kinase 8 0.00664783
CD99 CD99 molecule 0.00663958
LRRN3 leucine rich repeat neuronal 3 0.00663424
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle) 0.00662012
GFAP glial fibrillary acidic protein 0.00661886
GABARAPL1 GABA(A) receptor-associated protein like 1 0.00661376
AMIGO2 adhesion molecule with Ig-like domain 2 0.0066022
FGFR1 fibroblast growth factor receptor 1 0.00659808
DIO2 deiodinase, iodothyronine, type II 0.00659144
TNIK TRAF2 and NCK interacting kinase 0.0065848
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) 0.00654008
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.00653688
XAF1 XIAP associated factor 1 0.00653553
KDM3A lysine (K)-specific demethylase 3A 0.00651479
SSX1 synovial sarcoma, X breakpoint 1 0.00651196
RHOH ras homolog family member H 0.00649451
PRSS23 protease, serine, 23 0.00648963
TRIB3 tribbles pseudokinase 3 0.00648596
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 0.00648486
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 0.00646904
COPB2 coatomer protein complex, subunit beta 2 (beta prime) 0.00646265
TMEM158 transmembrane protein 158 (gene/pseudogene) 0.00646245
NPR3 natriuretic peptide receptor 3 0.00644988
NNT nicotinamide nucleotide transhydrogenase 0.006438
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) 0.00641696
MYOT myotilin 0.00640326
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 0.00639423
GOLM1 golgi membrane protein 1 0.00639
MED13 mediator complex subunit 13 0.00638441
ATP8B4 ATPase, class I, type 8B, member 4 0.00638118
NFIL3 nuclear factor, interleukin 3 regulated 0.00637517
EGR1 early growth response 1 0.00635262
DSG1 desmoglein 1 0.00634908
COL4A6 collagen, type IV, alpha 6 0.00633836
WNT5A wingless-type MMTV integration site family, member 5A 0.0063228
PDE4B phosphodiesterase 4B, cAMP-specific 0.00632034
ACTN2 actinin, alpha 2 0.00631653
ITK IL2-inducible T-cell kinase 0.00628706
IFI6 interferon, alpha-inducible protein 6 0.00626215
RAD23B RAD23 homolog B (S. cerevisiae) 0.00625742
CD151 CD151 molecule (Raph blood group) 0.00625681
NR4A3 nuclear receptor subfamily 4, group A, member 3 0.00625392
PRTN3 proteinase 3 0.00624801
PRDX1 peroxiredoxin 1 0.00624748
DSC2 desmocollin 2 0.00624652
SPRR1B small proline-rich protein 1B 0.00623892
AHCYL1 adenosylhomocysteinase-like 1 0.00620246
KRT15 keratin 15, type I 0.0062022
CA2 carbonic anhydrase II 0.00617595
CA3 carbonic anhydrase III 0.00615938
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 0.00615441
SOD2 superoxide dismutase 2, mitochondrial 0.00614778
GPM6A glycoprotein M6A 0.0061366

decreased expression

Symbol Name Standardized Value
CXCL12 chemokine (C-X-C motif) ligand 12 -0.0190746
METTL7A methyltransferase like 7A -0.0178587
ADIRF adipogenesis regulatory factor -0.015772
GPX3 glutathione peroxidase 3 -0.0150632
THBS1 thrombospondin 1 -0.014262
CYBA cytochrome b-245, alpha polypeptide -0.0142187
CPVL carboxypeptidase, vitellogenic-like -0.0139233
ASRGL1 asparaginase like 1 -0.0137501
TFPI2 tissue factor pathway inhibitor 2 -0.0135482
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 -0.0134829
MAL mal, T-cell differentiation protein -0.0132277
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) -0.0130444
ARHGAP29 Rho GTPase activating protein 29 -0.0127742
IGFBP5 insulin-like growth factor binding protein 5 -0.0125516
SGCE sarcoglycan, epsilon -0.0123974
LCN2 lipocalin 2 -0.0121398
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) -0.0120719
TSPYL5 TSPY-like 5 -0.0118066
ACAT1 acetyl-CoA acetyltransferase 1 -0.0116818
CYFIP2 cytoplasmic FMR1 interacting protein 2 -0.0115502
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 -0.0114134
ADD3 adducin 3 (gamma) -0.0113552
DACT1 dishevelled-binding antagonist of beta-catenin 1 -0.0113508
DPYSL2 dihydropyrimidinase-like 2 -0.0111466
RGS5 regulator of G-protein signaling 5 -0.0110893
SFRP1 secreted frizzled-related protein 1 -0.0110851
NID2 nidogen 2 (osteonidogen) -0.0109821
NPY1R neuropeptide Y receptor Y1 -0.0109374
CD200 CD200 molecule -0.0108588
FST follistatin -0.0108211
BEX4 brain expressed, X-linked 4 -0.0106904
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) -0.0106449
LAMP5 lysosomal-associated membrane protein family, member 5 -0.0105885
PROM1 prominin 1 -0.0105403
ALB albumin -0.0103108
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2) -0.0102938
SYNE3 spectrin repeat containing, nuclear envelope family member 3 -0.010276
MLF1 myeloid leukemia factor 1 -0.0102716
ESR1 estrogen receptor 1 -0.0102617
SH3TC1 SH3 domain and tetratricopeptide repeats 1 -0.0102491
GAS6 growth arrest-specific 6 -0.010207
ARID4A AT rich interactive domain 4A (RBP1-like) -0.010101
KCTD12 potassium channel tetramerization domain containing 12 -0.0100677
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) -0.0100674
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial -0.0100514
ZBTB18 zinc finger and BTB domain containing 18 -0.0100435
PLLP plasmolipin -0.0100275
FKBP1B FK506 binding protein 1B, 12.6 kDa -0.00994033
GUCY1A3 guanylate cyclase 1, soluble, alpha 3 -0.00993565
TPPP3 tubulin polymerization-promoting protein family member 3 -0.00986054
ANPEP alanyl (membrane) aminopeptidase -0.00981349
DEFB1 defensin, beta 1 -0.00980343
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -0.00977428
FAM171A1 family with sequence similarity 171, member A1 -0.00970708
ICAM2 intercellular adhesion molecule 2 -0.00970588
CRIP2 cysteine-rich protein 2 -0.00967937
STC1 stanniocalcin 1 -0.00966428
C7 complement component 7 -0.00963918
HMGN3 high mobility group nucleosomal binding domain 3 -0.00962166
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -0.00938496
TMSB15A thymosin beta 15a -0.0093781
ACAT2 acetyl-CoA acetyltransferase 2 -0.00932349
AEBP1 AE binding protein 1 -0.00928892
ZSCAN18 zinc finger and SCAN domain containing 18 -0.00926965
MGP matrix Gla protein -0.00925939
FXYD2 FXYD domain containing ion transport regulator 2 -0.00921574
THBS2 thrombospondin 2 -0.00921537
DHCR24 24-dehydrocholesterol reductase -0.00920655
RELN reelin -0.00916456
GLDC glycine dehydrogenase (decarboxylating) -0.00911759
KIF1A kinesin family member 1A -0.00903539
PXMP2 peroxisomal membrane protein 2, 22kDa -0.00901243
CLEC3B C-type lectin domain family 3, member B -0.00897445
BEX1 brain expressed, X-linked 1 -0.00885455
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 -0.00885432
BICC1 BicC family RNA binding protein 1 -0.00881956
CPE carboxypeptidase E -0.00881828
OLFM4 olfactomedin 4 -0.0087622
RAP1GAP2 RAP1 GTPase activating protein 2 -0.0087566
GNG11 guanine nucleotide binding protein (G protein), gamma 11 -0.00871354
TADA2A transcriptional adaptor 2A -0.00866477
CFI complement factor I -0.00865493
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 -0.00865001
AOX1 aldehyde oxidase 1 -0.00863619
EPCAM epithelial cell adhesion molecule -0.00852366
H1-10 H1.10 linker histone -0.0085167
PDGFRA platelet-derived growth factor receptor, alpha polypeptide -0.0084934
COLEC11 collectin sub-family member 11 -0.00849216
ALCAM activated leukocyte cell adhesion molecule -0.0084877
ASPN asporin -0.00845049
CD302 CD302 molecule -0.00843121
C5ORF30 chromosome 5 open reading frame 30 -0.00842139
ZNF423 zinc finger protein 423 -0.00841688
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B -0.00840721
IFRD2 interferon-related developmental regulator 2 -0.00840366
KRT19 keratin 19, type I -0.00835614
ADGRG6 adhesion G protein-coupled receptor G6 -0.00830358
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 -0.00827291
AHCY adenosylhomocysteinase -0.00824251
FADS1 fatty acid desaturase 1 -0.00818195
AKR1C1 aldo-keto reductase family 1, member C1 -0.00816657
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -0.00813352
DEFA4 defensin, alpha 4, corticostatin -0.00809834
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A -0.0080959
VNN1 vanin 1 -0.00802632
AFP alpha-fetoprotein -0.00802281
PNN pinin, desmosome associated protein -0.00798125
BHLHE41 basic helix-loop-helix family, member e41 -0.00797812
COL9A3 collagen, type IX, alpha 3 -0.00796073
VCAN versican -0.00794415
FLRT3 fibronectin leucine rich transmembrane protein 3 -0.00794398
AHR aryl hydrocarbon receptor -0.00791463
DACH1 dachshund family transcription factor 1 -0.0079026
ANXA3 annexin A3 -0.00788882
IPO13 importin 13 -0.00787421
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein -0.00786855
LAMB1 laminin, beta 1 -0.00785912
ADI1 acireductone dioxygenase 1 -0.00785386
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -0.00784922
PLN phospholamban -0.00779763
FGL2 fibrinogen-like 2 -0.00778193
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 -0.0077806
RASL11B RAS-like, family 11, member B -0.00775905
CAPN1 calpain 1, (mu/I) large subunit -0.0077189
RGS4 regulator of G-protein signaling 4 -0.00771557
UGCG UDP-glucose ceramide glucosyltransferase -0.00771325
IDI1 isopentenyl-diphosphate delta isomerase 1 -0.00771291
RNF144A ring finger protein 144A -0.00769575
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 -0.00769495
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 -0.00769163
CCNE2 cyclin E2 -0.00768374
CDH1 cadherin 1, type 1, E-cadherin (epithelial) -0.0076597
EMP2 epithelial membrane protein 2 -0.00765648
GCHFR GTP cyclohydrolase I feedback regulator -0.00764519
PDZRN3 PDZ domain containing ring finger 3 -0.00764148
PECR peroxisomal trans-2-enoyl-CoA reductase -0.00759952
PCOLCE procollagen C-endopeptidase enhancer -0.00758602
GCA grancalcin, EF-hand calcium binding protein -0.00757605
ALDOB aldolase B, fructose-bisphosphate -0.0075676
C3ORF14 chromosome 3 open reading frame 14 -0.00756079
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 -0.00750418
GSTM3 glutathione S-transferase mu 3 (brain) -0.00748457
PLAT plasminogen activator, tissue -0.00746284
TWIST1 twist family bHLH transcription factor 1 -0.00745472
DCXR dicarbonyl/L-xylulose reductase -0.00745247
DCN decorin -0.00743616
G0S2 G0/G1 switch 2 -0.00743054
ARMCX1 armadillo repeat containing, X-linked 1 -0.00734504
THY1 Thy-1 cell surface antigen -0.00734286
AHSG alpha-2-HS-glycoprotein -0.00731738
ASGR2 asialoglycoprotein receptor 2 -0.00730285
PCP4 Purkinje cell protein 4 -0.00728485
PDGFRL platelet-derived growth factor receptor-like -0.00727745
MFAP5 microfibrillar associated protein 5 -0.00724684
MECOM MDS1 and EVI1 complex locus -0.00723851
PEG10 paternally expressed 10 -0.00720937
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -0.00720664
GHR growth hormone receptor -0.00720454
LEFTY1 left-right determination factor 1 -0.00719218
DNASE1L3 deoxyribonuclease I-like 3 -0.00716638
SLIT1 slit homolog 1 (Drosophila) -0.00714654
LYZ lysozyme -0.00712745
ZCCHC24 zinc finger, CCHC domain containing 24 -0.0071243
AMBP alpha-1-microglobulin/bikunin precursor -0.00711512
HOXC6 homeobox C6 -0.00709133
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor -0.00708445
FZD6 frizzled class receptor 6 -0.00706899
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b -0.00705783
PAN2 PAN2 poly(A) specific ribonuclease subunit -0.00705454
COL14A1 collagen, type XIV, alpha 1 -0.00704924
DPEP1 dipeptidase 1 (renal) -0.0070178
SQLE squalene epoxidase -0.00701375
GAS1 growth arrest-specific 1 -0.00699959
VPS51 vacuolar protein sorting 51 homolog (S. cerevisiae) -0.00698433
APOH apolipoprotein H (beta-2-glycoprotein I) -0.00697268
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) -0.00696743
HTRA1 HtrA serine peptidase 1 -0.00686036
CAMP cathelicidin antimicrobial peptide -0.00685165
TFDP1 transcription factor Dp-1 -0.00685026
TOB1 transducer of ERBB2, 1 -0.00684785
GUK1 guanylate kinase 1 -0.0068168
C14ORF132 chromosome 14 open reading frame 132 -0.00681615
NINJ2 ninjurin 2 -0.00681009
CLGN calmegin -0.00680456
RPA3 replication protein A3, 14kDa -0.00680037
ISYNA1 inositol-3-phosphate synthase 1 -0.0067928
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2 -0.00678124
CRISP3 cysteine-rich secretory protein 3 -0.00677504
BGN biglycan -0.00677365
AKR1C3 aldo-keto reductase family 1, member C3 -0.00675242
LOXL1 lysyl oxidase-like 1 -0.00672651
COBLL1 cordon-bleu WH2 repeat protein-like 1 -0.00670126
CCN2 cellular communication network factor 2 -0.00669545
TM4SF1 transmembrane 4 L six family member 1 -0.0066832
AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase -0.00668193
NUP210 nucleoporin 210kDa -0.00667588
TRMT112 tRNA methyltransferase 11-2 homolog (S. cerevisiae) -0.00664237
PEG3 paternally expressed 3 -0.0066385
GPX7 glutathione peroxidase 7 -0.00662704
AKR1C2 aldo-keto reductase family 1, member C2 -0.00661429
MTFR1 mitochondrial fission regulator 1 -0.00661188
GMDS GDP-mannose 4,6-dehydratase -0.00660073
FLOT2 flotillin 2 -0.00659697
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase -0.00659127
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) -0.00658163
F3 coagulation factor III (thromboplastin, tissue factor) -0.00657673
MAT2A methionine adenosyltransferase II, alpha -0.00657094
C9ORF3 chromosome 9 open reading frame 3 -0.00655696
OLFM1 olfactomedin 1 -0.00654782
SHMT1 serine hydroxymethyltransferase 1 (soluble) -0.00653227
RNASE6 ribonuclease, RNase A family, k6 -0.00651982
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) -0.00651169
NR2F2 nuclear receptor subfamily 2, group F, member 2 -0.0065055
GPX2 glutathione peroxidase 2 -0.00648866
EXOSC4 exosome component 4 -0.00647618
H2AFV H2A histone family, member V -0.00647403
PLXNC1 plexin C1 -0.006451
PNMA8A PNMA family member 8A -0.00645025
TMEM50B transmembrane protein 50B -0.00643543
APOLD1 apolipoprotein L domain containing 1 -0.00642634
ZDHHC14 zinc finger, DHHC-type containing 14 -0.00642404
PIMREG PICALM interacting mitotic regulator -0.00641975
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 -0.0064137
CALD1 caldesmon 1 -0.00640275
BLNK B-cell linker -0.0064025
CRYZ crystallin, zeta (quinone reductase) -0.00639751
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) -0.00636133
LMCD1 LIM and cysteine-rich domains 1 -0.00634396
ZC2HC1A zinc finger, C2HC-type containing 1A -0.00634337
MATN2 matrilin 2 -0.00632254
ITM2C integral membrane protein 2C -0.00632023
ADCY1 adenylate cyclase 1 (brain) -0.00629931
FAR2 fatty acyl CoA reductase 2 -0.00629228
PDE1A phosphodiesterase 1A, calmodulin-dependent -0.00628564
SOCS2 suppressor of cytokine signaling 2 -0.00628468
FAM107A family with sequence similarity 107, member A -0.00627827
FRZB frizzled-related protein -0.00627621
RUVBL1 RuvB-like AAA ATPase 1 -0.006274
AGTR1 angiotensin II receptor, type 1 -0.00625346
THBD thrombomodulin -0.00625207
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 -0.00624842
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 -0.00624834
STEAP1 six transmembrane epithelial antigen of the prostate 1 -0.00622455
FHL1 four and a half LIM domains 1 -0.00622413
CDH2 cadherin 2, type 1, N-cadherin (neuronal) -0.00622303
WFDC2 WAP four-disulfide core domain 2 -0.00620599
CTSK cathepsin K -0.00618584
MXRA8 matrix-remodelling associated 8 -0.00618539
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4 -0.00617671
MPZL1 myelin protein zero-like 1 -0.00615119