PPP2R4 Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description protein phosphatase 2A activator, regulatory subunit 4|Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 5524)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/MORF_PPP2R4
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Genes

50 co-expressed genes for PPP2R4 from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
AP2M1 adaptor-related protein complex 2, mu 1 subunit
ATOX1 antioxidant 1 copper chaperone
ATP5J2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2
BANF1 barrier to autointegration factor 1
BUD31 BUD31 homolog (S. cerevisiae)
C9ORF16 chromosome 9 open reading frame 16
CAPNS1 calpain, small subunit 1
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase
CFDP1 craniofacial development protein 1
CNIH1 cornichon family AMPA receptor auxiliary protein 1
CNPY2 canopy FGF signaling regulator 2
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa
EIF4E2 eukaryotic translation initiation factor 4E family member 2
ETFA electron-transfer-flavoprotein, alpha polypeptide
HSBP1 heat shock factor binding protein 1
MORF4L2 mortality factor 4 like 2
NDUFA1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa
NDUFB1 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa
NEDD8 neural precursor cell expressed, developmentally down-regulated 8
NME2 NME/NM23 nucleoside diphosphate kinase 2
PDCD6 programmed cell death 6
POLR2H polymerase (RNA) II (DNA directed) polypeptide H
PPP1R7 protein phosphatase 1, regulatory subunit 7
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4
PRMT1 protein arginine methyltransferase 1
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
RAD23B RAD23 homolog B (S. cerevisiae)
RER1 retention in endoplasmic reticulum sorting receptor 1
SIVA1 SIVA1, apoptosis-inducing factor
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
SPTLC1 serine palmitoyltransferase, long chain base subunit 1
TBCA tubulin folding cofactor A
TCEB2 transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)
TM9SF1 transmembrane 9 superfamily member 1
TMBIM6 transmembrane BAX inhibitor motif containing 6
TMED10 transmembrane emp24-like trafficking protein 10 (yeast)
TMED2 transmembrane emp24 domain trafficking protein 2
TMEM147 transmembrane protein 147
UBA1 ubiquitin-like modifier activating enzyme 1
UQCRB ubiquinol-cytochrome c reductase binding protein
URM1 ubiquitin related modifier 1
VCP valosin containing protein
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae)
VTI1B vesicle transport through interaction with t-SNAREs 1B
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta