PPP5C Gene Set

Dataset DEPOD Substrates of Phosphatases
Category physical interactions
Type phosphatase
Description protein phosphatase 5, catalytic subunit|This gene encodes a serine/threonine phosphatase which is a member of the protein phosphatase catalytic subunit family. Proteins in this family participate in pathways regulated by reversible phosphorylation at serine and threonine residues; many of these pathways are involved in the regulation of cell growth and differentiation. The product of this gene has been shown to participate in signaling pathways in response to hormones or cellular stress, and elevated levels of this protein may be associated with breast cancer development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2011] (NCBI Entrez Gene Database, 5536)
External Link http://www.koehn.embl.de/depod/showp.php?gene=PPP5C
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Genes

7 substrates of the phosphatase PPP5C from the curated DEPOD Substrates of Phosphatases dataset.

Symbol Name
BAD BCL2-associated agonist of cell death
CDC37 cell division cycle 37
ICK intestinal cell (MAK-like) kinase
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAPT microtubule-associated protein tau
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase