PPP5C Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description protein phosphatase 5, catalytic subunit|This gene encodes a serine/threonine phosphatase which is a member of the protein phosphatase catalytic subunit family. Proteins in this family participate in pathways regulated by reversible phosphorylation at serine and threonine residues; many of these pathways are involved in the regulation of cell growth and differentiation. The product of this gene has been shown to participate in signaling pathways in response to hormones or cellular stress, and elevated levels of this protein may be associated with breast cancer development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2011] (NCBI Entrez Gene Database, 5536)
External Link https://ncbi.nlm.nih.gov/gene/5536
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Genes

498 genes differentially expressed following the PPP5C gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
SSBP2 single-stranded DNA binding protein 2 0.0150524
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 0.00975908
LYZ lysozyme 0.00788119
WDR61 WD repeat domain 61 0.0075585
ZBTB18 zinc finger and BTB domain containing 18 0.00753026
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.00749672
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 0.00748912
CXCR4 chemokine (C-X-C motif) receptor 4 0.00718886
GPR183 G protein-coupled receptor 183 0.00716498
HBB hemoglobin, beta 0.00715426
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 0.00690458
LEF1 lymphoid enhancer-binding factor 1 0.00685364
INSIG1 insulin induced gene 1 0.00683642
RPS5 ribosomal protein S5 0.00675748
DCK deoxycytidine kinase 0.00675107
AUTS2 autism susceptibility candidate 2 0.00629355
CCNA2 cyclin A2 0.00617229
CNPY3 canopy FGF signaling regulator 3 0.00616292
NREP neuronal regeneration related protein 0.00611787
HMGB2 high mobility group box 2 0.00592776
RPA3 replication protein A3, 14kDa 0.00589126
H1-0 H1.0 linker histone 0.00586486
DCXR dicarbonyl/L-xylulose reductase 0.00583479
JCHAIN joining chain of multimeric IgA and IgM 0.00582451
GUSBP3 glucuronidase, beta pseudogene 3 0.00579891
LCP1 lymphocyte cytosolic protein 1 (L-plastin) 0.00579456
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 0.00578667
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) 0.00577059
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 0.00564324
MSMO1 methylsterol monooxygenase 1 0.00561454
NUSAP1 nucleolar and spindle associated protein 1 0.005582
METRN meteorin, glial cell differentiation regulator 0.00555929
AURKB aurora kinase B 0.00546441
TMEM14B transmembrane protein 14B 0.00545051
NSL1 NSL1, MIS12 kinetochore complex component 0.00543096
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 0.00535556
RAB25 RAB25, member RAS oncogene family 0.00530391
CHEK2 checkpoint kinase 2 0.00528728
SELENBP1 selenium binding protein 1 0.00528173
ANXA5 annexin A5 0.00520523
CHN1 chimerin 1 0.00520498
LARS1 leucyl-tRNA synthetase 1 0.00520208
DSE dermatan sulfate epimerase 0.00515977
CAPRIN1 cell cycle associated protein 1 0.00509606
CSTA cystatin A (stefin A) 0.00506933
CTSZ cathepsin Z 0.00502941
CKAP2 cytoskeleton associated protein 2 0.00500441
BIRC5 baculoviral IAP repeat containing 5 0.00498881
DHCR7 7-dehydrocholesterol reductase 0.00494486
RNF5 ring finger protein 5, E3 ubiquitin protein ligase 0.00487884
ASF1A anti-silencing function 1A histone chaperone 0.00487133
CKS2 CDC28 protein kinase regulatory subunit 2 0.0048553
SIRT3 sirtuin 3 0.00484066
CDK1 cyclin-dependent kinase 1 0.00482821
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G 0.00481308
RAB11A RAB11A, member RAS oncogene family 0.00478406
CHMP6 charged multivesicular body protein 6 0.00478023
B3GNT1 0.00476746
ATF1 activating transcription factor 1 0.00476042
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 0.00475233
SEC23A Sec23 homolog A (S. cerevisiae) 0.00472559
MBIP MAP3K12 binding inhibitory protein 1 0.00472259
SAP30 Sin3A-associated protein, 30kDa 0.00468382
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 0.00467784
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 0.00466986
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 0.0046393
RNASE6 ribonuclease, RNase A family, k6 0.00463768
PRDX2 peroxiredoxin 2 0.00463356
OBI1 ORC ubiquitin ligase 1 0.0046188
HPRT1 hypoxanthine phosphoribosyltransferase 1 0.00460304
OPN3 opsin 3 0.00459626
PCP4 Purkinje cell protein 4 0.00458944
CCR7 chemokine (C-C motif) receptor 7 0.0045832
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 0.00458092
ACSL5 acyl-CoA synthetase long-chain family member 5 0.00457928
ACAT2 acetyl-CoA acetyltransferase 2 0.00457799
CDCA4 cell division cycle associated 4 0.00457692
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide 0.00455691
RBM3 RNA binding motif (RNP1, RRM) protein 3 0.00455296
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 0.00453348
DHRS3 dehydrogenase/reductase (SDR family) member 3 0.0045146
FAM216A family with sequence similarity 216, member A 0.00448665
HBD hemoglobin, delta 0.00447934
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 0.00447849
BANF1 barrier to autointegration factor 1 0.00447467
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain 0.00446798
MAP2K6 mitogen-activated protein kinase kinase 6 0.00444493
ADI1 acireductone dioxygenase 1 0.00444489
RBM34 RNA binding motif protein 34 0.00442053
ZDHHC4 zinc finger, DHHC-type containing 4 0.00440601
CLEC4A C-type lectin domain family 4, member A 0.00440155
RACGAP1 Rac GTPase activating protein 1 0.00439334
COMMD10 COMM domain containing 10 0.00438494
EREG epiregulin 0.00435967
EAPP E2F-associated phosphoprotein 0.00434787
AP1AR adaptor-related protein complex 1 associated regulatory protein 0.00434459
PKM pyruvate kinase, muscle 0.00434434
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit 0.00431284
AIMP1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 0.0043067
MTCH2 mitochondrial carrier 2 0.00429959
HMBS hydroxymethylbilane synthase 0.00429692
KYNU kynureninase 0.00428964
DERA deoxyribose-phosphate aldolase (putative) 0.00428812
ADORA2B adenosine A2b receptor 0.004271
CEP57 centrosomal protein 57kDa 0.00426929
GPM6A glycoprotein M6A 0.00426885
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator 0.00426065
CST3 cystatin C 0.00425978
NR1H3 nuclear receptor subfamily 1, group H, member 3 0.00425291
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 0.00423222
PAK1IP1 PAK1 interacting protein 1 0.00422628
CRLF1 cytokine receptor-like factor 1 0.00421993
GPR65 G protein-coupled receptor 65 0.00419719
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 0.00419545
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 0.0041948
GINS1 GINS complex subunit 1 (Psf1 homolog) 0.00418541
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma 0.00415507
C12ORF29 chromosome 12 open reading frame 29 0.00415244
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 0.00414146
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 0.00414003
FEZ2 fasciculation and elongation protein zeta 2 (zygin II) 0.00412937
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 0.00412743
ATP5PD ATP synthase peripheral stalk subunit d 0.00411465
RUVBL1 RuvB-like AAA ATPase 1 0.00411183
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12 0.0041039
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.00409471
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.00407706
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit 0.00407518
TMEM168 transmembrane protein 168 0.00406774
ZCCHC10 zinc finger, CCHC domain containing 10 0.00406707
NEK2 NIMA-related kinase 2 0.00406512
CD302 CD302 molecule 0.00405723
ODC1 ornithine decarboxylase 1 0.00402275
RGS1 regulator of G-protein signaling 1 0.00400993
PLP2 proteolipid protein 2 (colonic epithelium-enriched) 0.00400598
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 0.00400087
RPIA ribose 5-phosphate isomerase A 0.00398799
FBP1 fructose-1,6-bisphosphatase 1 0.00397029
TPD52L2 tumor protein D52-like 2 0.00395624
CETN2 centrin, EF-hand protein, 2 0.00395204
SPC25 SPC25, NDC80 kinetochore complex component 0.00394713
PRELID3B PRELI domain containing 3B 0.0039371
HMGB3 high mobility group box 3 0.0039362
KIF15 kinesin family member 15 0.00393294
DEK DEK proto-oncogene 0.00392879
MS4A1 membrane-spanning 4-domains, subfamily A, member 1 0.00392582
ALAS2 5'-aminolevulinate synthase 2 0.0039238
S100P S100 calcium binding protein P 0.00392034
PAX6 paired box 6 0.00388842
TMA16 translation machinery associated 16 homolog (S. cerevisiae) 0.00388237
TMEM158 transmembrane protein 158 (gene/pseudogene) 0.00387508
CARHSP1 calcium regulated heat stable protein 1, 24kDa 0.00386434
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma 0.00386429
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) 0.00385964
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 0.00384843
EEF1E1 eukaryotic translation elongation factor 1 epsilon 1 0.00384761
TPM4 tropomyosin 4 0.00384161
SLC25A46 solute carrier family 25, member 46 0.00383866
ERAP1 endoplasmic reticulum aminopeptidase 1 0.00382538
GTF2A2 general transcription factor IIA, 2, 12kDa 0.00382052
GPR18 G protein-coupled receptor 18 0.00379486
UBE2N ubiquitin-conjugating enzyme E2N 0.003792
CEP68 centrosomal protein 68kDa 0.0037888
RPS26 ribosomal protein S26 0.00378713
LY75 lymphocyte antigen 75 0.00378107
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2 0.00376991
GCA grancalcin, EF-hand calcium binding protein 0.00375862
CD58 CD58 molecule 0.00375803
MMD monocyte to macrophage differentiation-associated 0.00375684
KRT19 keratin 19, type I 0.00375442
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 0.00374571
HIKESHI heat shock protein nuclear import factor hikeshi 0.00374411
PDE2A phosphodiesterase 2A, cGMP-stimulated 0.00374007
SH3YL1 SH3 and SYLF domain containing 1 0.00373885
TMEM14A transmembrane protein 14A 0.00373624
DDX18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 0.00373292
NUP37 nucleoporin 37kDa 0.00372667
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 0.00372534
GTF2H5 general transcription factor IIH, polypeptide 5 0.00372368
GGPS1 geranylgeranyl diphosphate synthase 1 0.00372037
THY1 Thy-1 cell surface antigen 0.00371608
IQGAP2 IQ motif containing GTPase activating protein 2 0.00371308
OIP5 Opa interacting protein 5 0.00369685
NIPSNAP2 nipsnap homolog 2 0.00369326
ACTL6A actin-like 6A 0.00368806
BLNK B-cell linker 0.00368126
HILPDA hypoxia inducible lipid droplet-associated 0.00367575
GPM6B glycoprotein M6B 0.0036698
TMEM126B transmembrane protein 126B 0.00365713
PUM2 pumilio RNA-binding family member 2 0.00365413
EIF3M eukaryotic translation initiation factor 3, subunit M 0.0036393
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 0.00363403
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 0.00362368
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 0.00362163
SEPP1 selenoprotein P, plasma, 1 0.00360992
RHOB ras homolog family member B 0.0036029
COA3 cytochrome c oxidase assembly factor 3 0.00359915
KIF11 kinesin family member 11 0.00359471
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) 0.00358614
TLK1 tousled-like kinase 1 0.00358209
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 0.00357956
XK X-linked Kx blood group 0.00357205
MRS2 MRS2 magnesium transporter 0.00356687
CUTC cutC copper transporter 0.00355153
PLEKHJ1 pleckstrin homology domain containing, family J member 1 0.00355106
SASH3 SAM and SH3 domain containing 3 0.00353534
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 0.0035282
AMD1 adenosylmethionine decarboxylase 1 0.00352161
CRIP2 cysteine-rich protein 2 0.00351852
CYCS cytochrome c, somatic 0.00351141
HAT1 histone acetyltransferase 1 0.00351099
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 0.00350554
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 0.00349511
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial 0.00349298
TCL1A T-cell leukemia/lymphoma 1A 0.00349104
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 0.00348914
IL7R interleukin 7 receptor 0.00348678
AURKA aurora kinase A 0.00348587
SRP9 signal recognition particle 9kDa 0.00348178
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme 0.00348128
ANKRD49 ankyrin repeat domain 49 0.00347534
DSN1 DSN1, MIS12 kinetochore complex component 0.00347049
SLC2A4RG SLC2A4 regulator 0.00346882
MARCHF7 membrane associated ring-CH-type finger 7 0.0034665
SSBP1 single-stranded DNA binding protein 1, mitochondrial 0.00346532
METTL18 methyltransferase like 18 0.00346289
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.00345904
MRPL20 mitochondrial ribosomal protein L20 0.00345733
THYN1 thymocyte nuclear protein 1 0.00345635
FHL1 four and a half LIM domains 1 0.00345609
MCM6 minichromosome maintenance complex component 6 0.00345539
NUP160 nucleoporin 160kDa 0.00345039
FABP1 fatty acid binding protein 1, liver 0.00344483
ASF1B anti-silencing function 1B histone chaperone 0.00344201
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) 0.00344041
PPIH peptidylprolyl isomerase H (cyclophilin H) 0.00343607
APOA1 apolipoprotein A-I 0.00343242
SDHAF3 succinate dehydrogenase complex assembly factor 3 0.00341539
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 0.00341075
PEX3 peroxisomal biogenesis factor 3 0.00340992
ZNF652 zinc finger protein 652 0.00339911
NIP7 NIP7, nucleolar pre-rRNA processing protein 0.00339855
PEX2 peroxisomal biogenesis factor 2 0.00339601
C1QBP complement component 1, q subcomponent binding protein 0.00339547
JPT1 Jupiter microtubule associated homolog 1 0.00339519
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 0.00338825
FKBP1B FK506 binding protein 1B, 12.6 kDa 0.0033874
RAD23B RAD23 homolog B (S. cerevisiae) 0.00337948
MOCS2 molybdenum cofactor synthesis 2 0.00337914
CD3E CD3e molecule, epsilon (CD3-TCR complex) 0.00337906

decreased expression

Symbol Name Standardized Value
BAMBI BMP and activin membrane-bound inhibitor -0.0147498
HMOX1 heme oxygenase 1 -0.0107606
GNAS GNAS complex locus -0.0101304
GPNMB glycoprotein (transmembrane) nmb -0.00931521
KRT7 keratin 7, type II -0.00907981
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 -0.00892878
HSPB8 heat shock 22kDa protein 8 -0.00838025
C3 complement component 3 -0.00826013
FNDC3B fibronectin type III domain containing 3B -0.00820831
IFI27 interferon, alpha-inducible protein 27 -0.00793535
CXCL8 chemokine (C-X-C motif) ligand 8 -0.00793524
KCNK1 potassium channel, two pore domain subfamily K, member 1 -0.00792582
MTUS1 microtubule associated tumor suppressor 1 -0.0077622
LCN2 lipocalin 2 -0.00757635
JAG1 jagged 1 -0.00732904
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 -0.00727654
KRT17 keratin 17, type I -0.00714679
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -0.00707578
DHRS2 dehydrogenase/reductase (SDR family) member 2 -0.0070734
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) -0.00707209
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b -0.00700113
HSPA1A heat shock 70kDa protein 1A -0.00678445
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B -0.0066342
MMP7 matrix metallopeptidase 7 -0.00657551
PLXND1 plexin D1 -0.00641112
SGK1 serum/glucocorticoid regulated kinase 1 -0.0063979
ASS1 argininosuccinate synthase 1 -0.00636298
GLA galactosidase, alpha -0.00635999
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 -0.00634389
MVP major vault protein -0.00628648
HSPA2 heat shock 70kDa protein 2 -0.00624023
CFB complement factor B -0.00618903
SIRPA signal-regulatory protein alpha -0.00617687
KRT23 keratin 23, type I -0.00614798
PIEZO1 piezo-type mechanosensitive ion channel component 1 -0.0061442
KRT14 keratin 14, type I -0.00609254
MXRA5 matrix-remodelling associated 5 -0.0060845
COL4A5 collagen, type IV, alpha 5 -0.00602055
APOD apolipoprotein D -0.00600765
CLEC2B C-type lectin domain family 2, member B -0.0057933
ALAS1 5'-aminolevulinate synthase 1 -0.00579222
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1) -0.00577911
PLK2 polo-like kinase 2 -0.00577601
USP9X ubiquitin specific peptidase 9, X-linked -0.00573252
LYN LYN proto-oncogene, Src family tyrosine kinase -0.00569968
CXCL10 chemokine (C-X-C motif) ligand 10 -0.00565751
MX1 MX dynamin-like GTPase 1 -0.00565077
DNM1L dynamin 1-like -0.00562788
PLAAT3 phospholipase A and acyltransferase 3 -0.00558569
CX3CR1 chemokine (C-X3-C motif) receptor 1 -0.00553294
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -0.00550955
CXCL5 chemokine (C-X-C motif) ligand 5 -0.00545745
IGF1R insulin-like growth factor 1 receptor -0.0054554
NUAK1 NUAK family, SNF1-like kinase, 1 -0.00543158
ANKRD11 ankyrin repeat domain 11 -0.00540836
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B -0.00537903
MFSD12 major facilitator superfamily domain containing 12 -0.00535929
TCTA T-cell leukemia translocation altered -0.00533622
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 -0.00533449
NKX2-2 NK2 homeobox 2 -0.0053128
PIR pirin (iron-binding nuclear protein) -0.00530293
SUSD6 sushi domain containing 6 -0.0052919
SNAP25 synaptosomal-associated protein, 25kDa -0.00526093
KLK11 kallikrein-related peptidase 11 -0.00523902
ATF3 activating transcription factor 3 -0.0052268
COL16A1 collagen, type XVI, alpha 1 -0.00517716
PKD1P1 polycystic kidney disease 1 (autosomal dominant) pseudogene 1 -0.00516971
TUBB6 tubulin, beta 6 class V -0.00516835
DEPTOR DEP domain containing MTOR-interacting protein -0.00516184
WWC1 WW and C2 domain containing 1 -0.00515459
DAPK1 death-associated protein kinase 1 -0.00514659
JAK1 Janus kinase 1 -0.00513434
IFI44L interferon-induced protein 44-like -0.00512691
SPON2 spondin 2, extracellular matrix protein -0.00511572
BMP2 bone morphogenetic protein 2 -0.00510961
WARS1 tryptophanyl-tRNA synthetase 1 -0.00510816
NPEPL1 aminopeptidase-like 1 -0.00510698
SCPEP1 serine carboxypeptidase 1 -0.00509835
RNF167 ring finger protein 167 -0.00507048
ADGRG2 adhesion G protein-coupled receptor G2 -0.00505367
HMG20B high mobility group 20B -0.00503957
SPP1 secreted phosphoprotein 1 -0.0050124
GABARAPL1 GABA(A) receptor-associated protein like 1 -0.00500876
GOLGA8H golgin A8 family, member H -0.00500037
WIPI1 WD repeat domain, phosphoinositide interacting 1 -0.00496102
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15 -0.00495006
SAMD4A sterile alpha motif domain containing 4A -0.00491348
IER5 immediate early response 5 -0.00488967
SASH1 SAM and SH3 domain containing 1 -0.00488887
TPSAB1 tryptase alpha/beta 1 -0.00488334
IFI6 interferon, alpha-inducible protein 6 -0.0048686
BRD4 bromodomain containing 4 -0.00486851
BHLHE41 basic helix-loop-helix family, member e41 -0.00482296
TIMP2 TIMP metallopeptidase inhibitor 2 -0.00480935
GPR137B G protein-coupled receptor 137B -0.00480903
CAV1 caveolin 1, caveolae protein, 22kDa -0.00480736
TSPYL5 TSPY-like 5 -0.00477728
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -0.00475762
GATA2 GATA binding protein 2 -0.00475292
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) -0.00475011
MAOB monoamine oxidase B -0.00474706
IPO13 importin 13 -0.00474308
HSPA6 heat shock 70kDa protein 6 (HSP70B') -0.00474279
MAST4 microtubule associated serine/threonine kinase family member 4 -0.00471336
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 -0.00468632
APOL1 apolipoprotein L, 1 -0.004674
CEBPB CCAAT/enhancer binding protein (C/EBP), beta -0.00466818
PTK2 protein tyrosine kinase 2 -0.00465232
GDF15 growth differentiation factor 15 -0.00464163
HDLBP high density lipoprotein binding protein -0.00463965
MYOF myoferlin -0.00460686
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) -0.00458695
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 -0.00455598
TRIM22 tripartite motif containing 22 -0.00455442
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form) -0.00455312
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 -0.0045421
RAB11FIP1 RAB11 family interacting protein 1 (class I) -0.00452328
IFI16 interferon, gamma-inducible protein 16 -0.00451183
KIAA0930 KIAA0930 -0.00449742
CTSK cathepsin K -0.00448302
SMAD3 SMAD family member 3 -0.00447793
FAM110B family with sequence similarity 110, member B -0.00446047
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa -0.00444061
MLPH melanophilin -0.0044404
EDN1 endothelin 1 -0.00443826
MBOAT7 membrane bound O-acyltransferase domain containing 7 -0.0044381
FAM107A family with sequence similarity 107, member A -0.00443405
CLDN1 claudin 1 -0.00443068
FOXJ3 forkhead box J3 -0.00441215
MCM2 minichromosome maintenance complex component 2 -0.00440745
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 -0.0043979
UBR4 ubiquitin protein ligase E3 component n-recognin 4 -0.00438891
SNAI2 snail family zinc finger 2 -0.00438162
LIPG lipase, endothelial -0.00436931
ZC3HAV1 zinc finger CCCH-type, antiviral 1 -0.00436655
TRIM29 tripartite motif containing 29 -0.00435152
ACADVL acyl-CoA dehydrogenase, very long chain -0.00433582
IGF2R insulin-like growth factor 2 receptor -0.00433371
UPK1B uroplakin 1B -0.00433151
YBX3 Y box binding protein 3 -0.00432132
MAP7D1 MAP7 domain containing 1 -0.00431884
PODXL podocalyxin-like -0.00431518
CLIC5 chloride intracellular channel 5 -0.00431127
CCND3 cyclin D3 -0.00429096
NFIB nuclear factor I/B -0.00427128
PLPP2 phospholipid phosphatase 2 -0.00424272
LAMP3 lysosomal-associated membrane protein 3 -0.00423304
COL9A2 collagen, type IX, alpha 2 -0.00423195
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase -0.00422523
FN1 fibronectin 1 -0.00422257
RRAGC Ras-related GTP binding C -0.0042105
PEG3 paternally expressed 3 -0.0042051
NPIPA1 nuclear pore complex interacting protein family, member A1 -0.00419634
ZNF706 zinc finger protein 706 -0.00417892
AKR1C1 aldo-keto reductase family 1, member C1 -0.00416154
CTSD cathepsin D -0.00415671
NCOR2 nuclear receptor corepressor 2 -0.0041561
SEC14L1 SEC14-like 1 (S. cerevisiae) -0.00414446
TMEM140 transmembrane protein 140 -0.00412067
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked -0.00411655
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa -0.00411162
JUP junction plakoglobin -0.00409012
WASF3 WAS protein family, member 3 -0.00408992
TRIB1 tribbles pseudokinase 1 -0.00407684
OSBPL1A oxysterol binding protein-like 1A -0.00406082
GBP2 guanylate binding protein 2, interferon-inducible -0.00405705
LIMCH1 LIM and calponin homology domains 1 -0.00404924
SQSTM1 sequestosome 1 -0.00404531
DPP4 dipeptidyl-peptidase 4 -0.00403783
KLK6 kallikrein-related peptidase 6 -0.00402982
MPDZ multiple PDZ domain protein -0.00402969
INHBA inhibin, beta A -0.00402754
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 -0.00402676
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1 -0.00402541
NEBL nebulette -0.00401701
STX4 syntaxin 4 -0.00400779
VLDLR very low density lipoprotein receptor -0.00398482
AKAP8L A kinase (PRKA) anchor protein 8-like -0.00398412
CAPN3 calpain 3, (p94) -0.00398395
IRS1 insulin receptor substrate 1 -0.00394216
MYH10 myosin, heavy chain 10, non-muscle -0.00394208
PFN2 profilin 2 -0.00394191
TJP2 tight junction protein 2 -0.00393802
TBX3 T-box 3 -0.00393767
ACOT9 acyl-CoA thioesterase 9 -0.00393621
GBP1 guanylate binding protein 1, interferon-inducible -0.00393506
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1 -0.00393339
PRAME preferentially expressed antigen in melanoma -0.00393179
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A -0.00393071
BBX bobby sox homolog (Drosophila) -0.00392976
NRCAM neuronal cell adhesion molecule -0.00391447
MID1 midline 1 -0.00391445
CDK5RAP3 CDK5 regulatory subunit associated protein 3 -0.00391379
MYH9 myosin, heavy chain 9, non-muscle -0.00391327
COBL cordon-bleu WH2 repeat protein -0.00391279
NCALD neurocalcin delta -0.00390955
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) -0.00390385
EIF5B eukaryotic translation initiation factor 5B -0.00390267
RNF44 ring finger protein 44 -0.00389657
RUNX3 runt-related transcription factor 3 -0.00389464
AFF1 AF4/FMR2 family, member 1 -0.00389111
GOLGA8A golgin A8 family, member A -0.00388943
TFF1 trefoil factor 1 -0.00388293
OGT O-linked N-acetylglucosamine (GlcNAc) transferase -0.00388095
AP3D1 adaptor-related protein complex 3, delta 1 subunit -0.00387547
CNTN1 contactin 1 -0.00387529
CASP10 caspase 10, apoptosis-related cysteine peptidase -0.00386976
ARHGAP29 Rho GTPase activating protein 29 -0.00386643
SPRED2 sprouty-related, EVH1 domain containing 2 -0.003864
GOLGB1 golgin B1 -0.0038615
NPDC1 neural proliferation, differentiation and control, 1 -0.00385999
VWF von Willebrand factor -0.00385499
MITF microphthalmia-associated transcription factor -0.00385136
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 -0.0038438
SST somatostatin -0.00383178
NPY1R neuropeptide Y receptor Y1 -0.00383016
RTCA RNA 3'-terminal phosphate cyclase -0.00382915
NPC1 Niemann-Pick disease, type C1 -0.00382641
EGR1 early growth response 1 -0.00382398
PLA1A phospholipase A1 member A -0.00382388
BST2 bone marrow stromal cell antigen 2 -0.00382016
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 -0.00381526
FXYD2 FXYD domain containing ion transport regulator 2 -0.00381509
EIF6 eukaryotic translation initiation factor 6 -0.00381222
MSN moesin -0.00381203
ZRSR2 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 -0.00380944
TGFBR3 transforming growth factor, beta receptor III -0.00380719
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6 -0.00380534
S100A8 S100 calcium binding protein A8 -0.00380369
PABPC3 poly(A) binding protein, cytoplasmic 3 -0.00379918
KLF6 Kruppel-like factor 6 -0.00379468
TNC tenascin C -0.00378976
TAPBP TAP binding protein (tapasin) -0.00378496
LARP1 La ribonucleoprotein domain family, member 1 -0.00377976
MAGED1 melanoma antigen family D1 -0.00377591
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 -0.00377107
VTCN1 V-set domain containing T cell activation inhibitor 1 -0.00375426
TNFAIP2 tumor necrosis factor, alpha-induced protein 2 -0.00375141
AHNAK AHNAK nucleoprotein -0.00375083
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3 -0.00374795
TENT5A terminal nucleotidyltransferase 5A -0.00374387
BMP7 bone morphogenetic protein 7 -0.00374282
SLC38A1 solute carrier family 38, member 1 -0.00374043
RSAD2 radical S-adenosyl methionine domain containing 2 -0.00373969
DDRGK1 DDRGK domain containing 1 -0.00373778
SIDT2 SID1 transmembrane family, member 2 -0.00373494
SIK1 salt-inducible kinase 1 -0.00371362
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 -0.00370784