PPP6C Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description protein phosphatase 6, catalytic subunit|This gene encodes the catalytic subunit of protein phosphatase, a component of a signaling pathway regulating cell cycle progression. Splice variants encoding different protein isoforms exist. The pseudogene of this gene is located on chromosome X. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 5537)
External Link https://ncbi.nlm.nih.gov/gene/5537
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Genes

498 genes differentially expressed following the PPP6C gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
INSIG1 insulin induced gene 1 0.0158667
CXCL9 chemokine (C-X-C motif) ligand 9 0.0152035
PCP4 Purkinje cell protein 4 0.0151616
TMEM158 transmembrane protein 158 (gene/pseudogene) 0.0146065
NRGN neurogranin (protein kinase C substrate, RC3) 0.0145206
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 0.0144028
CD2 CD2 molecule 0.0143954
MMP9 matrix metallopeptidase 9 0.0142127
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 0.0132903
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 0.0132476
TSPAN4 tetraspanin 4 0.0126298
DPYD dihydropyrimidine dehydrogenase 0.012505
CD48 CD48 molecule 0.0124096
FST follistatin 0.0122735
ADAMDEC1 ADAM-like, decysin 1 0.0119708
CD8A CD8a molecule 0.0118363
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 0.0115723
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.0114619
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 0.011302
DCK deoxycytidine kinase 0.0111484
GZMK granzyme K (granzyme 3; tryptase II) 0.0111252
JCHAIN joining chain of multimeric IgA and IgM 0.0110329
CCNA2 cyclin A2 0.0109752
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.0108294
NIPSNAP2 nipsnap homolog 2 0.0107521
TMEM14B transmembrane protein 14B 0.0107386
TMEM106C transmembrane protein 106C 0.0107358
CCL5 chemokine (C-C motif) ligand 5 0.0106778
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) 0.0106707
LGALS2 lectin, galactoside-binding, soluble, 2 0.0106486
COMMD8 COMM domain containing 8 0.0105908
NPM3 nucleophosmin/nucleoplasmin 3 0.010565
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 0.0105222
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 0.0105104
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme 0.0104894
RPA3 replication protein A3, 14kDa 0.0103597
FCN1 ficolin (collagen/fibrinogen domain containing) 1 0.0102344
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 0.0101307
FAM162A family with sequence similarity 162, member A 0.0101096
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 0.0100769
NUSAP1 nucleolar and spindle associated protein 1 0.0100004
SEC23A Sec23 homolog A (S. cerevisiae) 0.00999387
LYZ lysozyme 0.00998565
COPS4 COP9 signalosome subunit 4 0.00994606
CLEC10A C-type lectin domain family 10, member A 0.00986923
THAP12 THAP domain containing 12 0.00960633
PCLAF PCNA clamp associated factor 0.00960442
KLRB1 killer cell lectin-like receptor subfamily B, member 1 0.00951153
RBX1 ring-box 1, E3 ubiquitin protein ligase 0.00951047
FGL2 fibrinogen-like 2 0.0094887
CHKB choline kinase beta 0.00944103
OLFM4 olfactomedin 4 0.00940388
ENC1 ectodermal-neural cortex 1 (with BTB domain) 0.009387
PTGER3 prostaglandin E receptor 3 (subtype EP3) 0.00934721
MDFIC MyoD family inhibitor domain containing 0.00927124
IL2RB interleukin 2 receptor, beta 0.00927058
TMX1 thioredoxin-related transmembrane protein 1 0.00913983
DCXR dicarbonyl/L-xylulose reductase 0.009104
PSRC1 proline/serine-rich coiled-coil 1 0.00908847
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 0.00905877
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 0.00904395
CCNB2 cyclin B2 0.00903763
LYN LYN proto-oncogene, Src family tyrosine kinase 0.00902741
NMU neuromedin U 0.00902665
KIF20A kinesin family member 20A 0.00897229
RANBP1 RAN binding protein 1 0.00894856
DEK DEK proto-oncogene 0.00893458
PRKCB protein kinase C, beta 0.00892942
CXCL10 chemokine (C-X-C motif) ligand 10 0.00891493
LTF lactotransferrin 0.00890425
TXNDC9 thioredoxin domain containing 9 0.00889819
TMEM126B transmembrane protein 126B 0.00889694
ATF1 activating transcription factor 1 0.0088922
CLCA1 chloride channel accessory 1 0.00888977
PLBD1 phospholipase B domain containing 1 0.00888751
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 0.0088027
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein 0.00877578
RPS4Y1 ribosomal protein S4, Y-linked 1 0.00874142
NKG7 natural killer cell granule protein 7 0.00873997
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G 0.00873006
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3 0.00872763
MMP12 matrix metallopeptidase 12 0.00868977
SELENOF selenoprotein F 0.00868432
CDC42 cell division cycle 42 0.00867405
PGAM1 phosphoglycerate mutase 1 (brain) 0.00864395
GINS1 GINS complex subunit 1 (Psf1 homolog) 0.00860973
SH3BGRL SH3 domain binding glutamate-rich protein like 0.00858686
RNASE6 ribonuclease, RNase A family, k6 0.0085791
RGS4 regulator of G-protein signaling 4 0.00856515
MAT2B methionine adenosyltransferase II, beta 0.00855336
APOC1 apolipoprotein C-I 0.00853176
SPTSSA serine palmitoyltransferase, small subunit A 0.00848993
CDCA4 cell division cycle associated 4 0.00846468
IGSF6 immunoglobulin superfamily, member 6 0.00842417
EVI2A ecotropic viral integration site 2A 0.00842387
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 0.0083899
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11 0.00835362
CNN3 calponin 3, acidic 0.00834993
BIRC5 baculoviral IAP repeat containing 5 0.00834455
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 0.0083207
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha 0.00831907
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit 0.00831347
PTTG1 pituitary tumor-transforming 1 0.00830934
ENO2 enolase 2 (gamma, neuronal) 0.00830249
ELOVL6 ELOVL fatty acid elongase 6 0.00830144
ACTL6A actin-like 6A 0.00827585
MRPL13 mitochondrial ribosomal protein L13 0.00826343
FGR FGR proto-oncogene, Src family tyrosine kinase 0.00824252
CRYL1 crystallin, lambda 1 0.00823474
SRP9 signal recognition particle 9kDa 0.00821507
LMNB1 lamin B1 0.00819577
GLO1 glyoxalase I 0.0081919
GTPBP8 GTP-binding protein 8 (putative) 0.00818443
GTF2A2 general transcription factor IIA, 2, 12kDa 0.0081412
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 0.00811919
CD9 CD9 molecule 0.0081017
MNDA myeloid cell nuclear differentiation antigen 0.00806649
HNMT histamine N-methyltransferase 0.0080209
CDK1 cyclin-dependent kinase 1 0.00798749
PPA2 pyrophosphatase (inorganic) 2 0.00798596
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 0.00792064
NDUFA6 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa 0.0079136
KYAT3 kynurenine aminotransferase 3 0.00791277
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 0.00791251
RACGAP1 Rac GTPase activating protein 1 0.00788255
MCM6 minichromosome maintenance complex component 6 0.00785125
BTBD2 BTB (POZ) domain containing 2 0.00784048
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide 0.00783668
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.00783039
DEFA4 defensin, alpha 4, corticostatin 0.00782882
MEIS2 Meis homeobox 2 0.00781864
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa 0.00781676
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.00779201
CST7 cystatin F (leukocystatin) 0.00778099
TSPAN6 tetraspanin 6 0.00774814
LST1 leukocyte specific transcript 1 0.00771485
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 0.00770668
XCL1 chemokine (C motif) ligand 1 0.00768976
TIPRL TOR signaling pathway regulator 0.00766775
IL10RA interleukin 10 receptor, alpha 0.00766728
SREBF1 sterol regulatory element binding transcription factor 1 0.00764704
WBP5 WW domain binding protein 5 0.00760232
HMGN4 high mobility group nucleosomal binding domain 4 0.00759105
LRRC40 leucine rich repeat containing 40 0.00758164
CCKBR cholecystokinin B receptor 0.00755584
GNG10 guanine nucleotide binding protein (G protein), gamma 10 0.00753653
OIP5 Opa interacting protein 5 0.00752777
RMI1 RecQ mediated genome instability 1 0.0075098
C1ORF174 chromosome 1 open reading frame 174 0.00750741
HMGB2 high mobility group box 2 0.00748088
CLEC7A C-type lectin domain family 7, member A 0.00748037
NEK2 NIMA-related kinase 2 0.00747578
PLN phospholamban 0.00745666
FADS1 fatty acid desaturase 1 0.00743977
CD200 CD200 molecule 0.00741724
TPSAB1 tryptase alpha/beta 1 0.00737223
EEF1E1 eukaryotic translation elongation factor 1 epsilon 1 0.00731791
EREG epiregulin 0.00731452
NSL1 NSL1, MIS12 kinetochore complex component 0.00729859
RBM3 RNA binding motif (RNP1, RRM) protein 3 0.00728598
TMEM38B transmembrane protein 38B 0.00728577
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 0.00728138
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.00727597
IKZF1 IKAROS family zinc finger 1 (Ikaros) 0.00726769
IL7 interleukin 7 0.00725462
TMEM14A transmembrane protein 14A 0.00725357
CDKN3 cyclin-dependent kinase inhibitor 3 0.00725105
GBP1 guanylate binding protein 1, interferon-inducible 0.00717516
SIVA1 SIVA1, apoptosis-inducing factor 0.00717344
CTSH cathepsin H 0.00716154
LTBP1 latent transforming growth factor beta binding protein 1 0.00715464
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.00715331
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.00714334
GSAP gamma-secretase activating protein 0.00713608
CD3D CD3d molecule, delta (CD3-TCR complex) 0.00712681
CKS2 CDC28 protein kinase regulatory subunit 2 0.00711951
HPRT1 hypoxanthine phosphoribosyltransferase 1 0.00711789
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B 0.00711747
ADAM9 ADAM metallopeptidase domain 9 0.00711445
PRKACB protein kinase, cAMP-dependent, catalytic, beta 0.00709783
SLAMF8 SLAM family member 8 0.00706937
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2 0.00706611
IL7R interleukin 7 receptor 0.00702295
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 0.00702241
LAIR2 leukocyte-associated immunoglobulin-like receptor 2 0.00701789
THBS1 thrombospondin 1 0.00701617
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase 0.00699492
CD52 CD52 molecule 0.00696779
TMSB15A thymosin beta 15a 0.00696731
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 0.00693455
ZDHHC4 zinc finger, DHHC-type containing 4 0.00691296
RXRA retinoid X receptor, alpha 0.00689821
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein) 0.00689671
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain 0.00689159
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 0.00685742
ZCCHC10 zinc finger, CCHC domain containing 10 0.00685636
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 0.00684408
CREBL2 cAMP responsive element binding protein-like 2 0.00683835
ALG6 ALG6, alpha-1,3-glucosyltransferase 0.00683556
NREP neuronal regeneration related protein 0.0068294
RNF130 ring finger protein 130 0.00682827
RSBN1 round spermatid basic protein 1 0.00682477
PIMREG PICALM interacting mitotic regulator 0.00682338
S100A9 S100 calcium binding protein A9 0.00681578
CKAP2 cytoskeleton associated protein 2 0.00681481
EFNB3 ephrin-B3 0.00681239
UBE2V2 ubiquitin-conjugating enzyme E2 variant 2 0.00680913
CD27 CD27 molecule 0.00679787
TSPOAP1 TSPO associated protein 1 0.00679753
CRYM crystallin, mu 0.00677131
RSL24D1 ribosomal L24 domain containing 1 0.00676608
AK4 adenylate kinase 4 0.00674806
TNFAIP8 tumor necrosis factor, alpha-induced protein 8 0.00674407
ZWINT ZW10 interacting kinetochore protein 0.00673518
BIN2 bridging integrator 2 0.00673207
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 0.00672903
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) 0.00672823
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) 0.00671864
MCTP1 multiple C2 domains, transmembrane 1 0.00670833
PRDX3 peroxiredoxin 3 0.0067079
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 0.00670328
ANKRD49 ankyrin repeat domain 49 0.00669531
HDAC2 histone deacetylase 2 0.00669484
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) 0.00668233
MPC2 mitochondrial pyruvate carrier 2 0.00664927
SELENBP1 selenium binding protein 1 0.00664926
MCUB mitochondrial calcium uniporter dominant negative subunit beta 0.00664897
SNRPG small nuclear ribonucleoprotein polypeptide G 0.00664859
BCL2A1 BCL2-related protein A1 0.00664501
NDUFA7 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa 0.00663477
RAPSN receptor-associated protein of the synapse 0.00663107
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 0.00662214
CXCL11 chemokine (C-X-C motif) ligand 11 0.0066179
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX) 0.00661228
CHIT1 chitinase 1 (chitotriosidase) 0.00660265
NTS neurotensin 0.00660216
LBR lamin B receptor 0.00659728
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 0.00659543
NUP160 nucleoporin 160kDa 0.00658719
RAB33A RAB33A, member RAS oncogene family 0.00657752
MS4A1 membrane-spanning 4-domains, subfamily A, member 1 0.00657271
AMD1 adenosylmethionine decarboxylase 1 0.00656421
NOL11 nucleolar protein 11 0.00656223
SNX7 sorting nexin 7 0.00656112
GPR88 G protein-coupled receptor 88 0.00654762
NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa 0.00654449
CD84 CD84 molecule 0.00654419
TFEC transcription factor EC 0.00653844
NUP54 nucleoporin 54kDa 0.00653216

decreased expression

Symbol Name Standardized Value
SSBP2 single-stranded DNA binding protein 2 -0.0219675
HSPA1A heat shock 70kDa protein 1A -0.0208474
IFI27 interferon, alpha-inducible protein 27 -0.0180518
AQP3 aquaporin 3 (Gill blood group) -0.0172405
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -0.0157428
ASS1 argininosuccinate synthase 1 -0.0156465
SPRED2 sprouty-related, EVH1 domain containing 2 -0.0156128
HMOX1 heme oxygenase 1 -0.0154274
ECM1 extracellular matrix protein 1 -0.0152242
AKR1C2 aldo-keto reductase family 1, member C2 -0.015077
S100P S100 calcium binding protein P -0.0144053
MGLL monoglyceride lipase -0.0141843
ATF3 activating transcription factor 3 -0.0141152
MX1 MX dynamin-like GTPase 1 -0.0138177
TCTA T-cell leukemia translocation altered -0.0134989
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 -0.0132792
AKR1C1 aldo-keto reductase family 1, member C1 -0.0130124
C8ORF4 chromosome 8 open reading frame 4 -0.0129529
CRYAB crystallin, alpha B -0.0129484
RRAGD Ras-related GTP binding D -0.0128542
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.0127839
TENT5A terminal nucleotidyltransferase 5A -0.0126725
HSPB8 heat shock 22kDa protein 8 -0.0125914
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 -0.0124702
DEFB1 defensin, beta 1 -0.0123642
KLF6 Kruppel-like factor 6 -0.0122691
MAP7 microtubule-associated protein 7 -0.0119628
ZMAT3 zinc finger, matrin-type 3 -0.0119242
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) -0.0118471
CCN2 cellular communication network factor 2 -0.011704
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b -0.0116919
DST dystonin -0.0116862
SCGB2A2 secretoglobin, family 2A, member 2 -0.0116584
MTUS1 microtubule associated tumor suppressor 1 -0.0116555
CSRP2 cysteine and glycine-rich protein 2 -0.0116306
BHLHE41 basic helix-loop-helix family, member e41 -0.011564
IER5 immediate early response 5 -0.0114634
ABLIM1 actin binding LIM protein 1 -0.0114237
CXCL5 chemokine (C-X-C motif) ligand 5 -0.0112851
ITPRID2 ITPR interacting domain containing 2 -0.0110578
TRIM29 tripartite motif containing 29 -0.0110432
MVP major vault protein -0.0109794
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 -0.0109227
PCDH9 protocadherin 9 -0.0108755
SLPI secretory leukocyte peptidase inhibitor -0.0108589
CLDN10 claudin 10 -0.0108528
RRAD Ras-related associated with diabetes -0.0107376
TM4SF1 transmembrane 4 L six family member 1 -0.0107369
SIK1 salt-inducible kinase 1 -0.0107034
TSPAN8 tetraspanin 8 -0.0105367
GPM6B glycoprotein M6B -0.0105212
RFTN1 raftlin, lipid raft linker 1 -0.0104645
RBMS1 RNA binding motif, single stranded interacting protein 1 -0.0104457
PLLP plasmolipin -0.0104375
CLIC5 chloride intracellular channel 5 -0.0103695
TUBB2B tubulin, beta 2B class IIb -0.0103621
PROM1 prominin 1 -0.0103583
RET ret proto-oncogene -0.010244
PPP1R15A protein phosphatase 1, regulatory subunit 15A -0.0101809
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 -0.0100717
LAMC2 laminin, gamma 2 -0.0100127
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B -0.00994372
EGR1 early growth response 1 -0.00993977
XIC X chromosome inactivation center -0.00993419
LMCD1 LIM and cysteine-rich domains 1 -0.00991062
NEBL nebulette -0.0098426
VCL vinculin -0.00979891
KLK10 kallikrein-related peptidase 10 -0.00977868
ISG15 ISG15 ubiquitin-like modifier -0.00971473
HOMER1 homer scaffolding protein 1 -0.00962782
RCAN1 regulator of calcineurin 1 -0.00959996
JAK1 Janus kinase 1 -0.00959761
MAGEA3 melanoma antigen family A3 -0.00959422
DYNLL1 dynein, light chain, LC8-type 1 -0.00958692
CXCL8 chemokine (C-X-C motif) ligand 8 -0.00952186
XPO7 exportin 7 -0.00950128
ABHD4 abhydrolase domain containing 4 -0.00949996
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 -0.00939167
NRCAM neuronal cell adhesion molecule -0.00936233
CLIP2 CAP-GLY domain containing linker protein 2 -0.00933702
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 -0.00921773
KLK6 kallikrein-related peptidase 6 -0.00918066
LAMP1 lysosomal-associated membrane protein 1 -0.00915761
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 -0.00914158
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase -0.00909993
MSN moesin -0.00905576
AHNAK2 AHNAK nucleoprotein 2 -0.00904529
PELI1 pellino E3 ubiquitin protein ligase 1 -0.00903899
CLU clusterin -0.00900716
PERP PERP, TP53 apoptosis effector -0.00893757
QPRT quinolinate phosphoribosyltransferase -0.00890213
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 -0.00886559
GOLGA8H golgin A8 family, member H -0.00883085
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 -0.00881598
MCL1 myeloid cell leukemia 1 -0.00879035
UBA1 ubiquitin-like modifier activating enzyme 1 -0.00875483
DHRS2 dehydrogenase/reductase (SDR family) member 2 -0.00873812
UBAP2 ubiquitin associated protein 2 -0.00873115
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 -0.00865207
FHL2 four and a half LIM domains 2 -0.00865051
PBX3 pre-B-cell leukemia homeobox 3 -0.00862466
TRIM16 tripartite motif containing 16 -0.00857345
GAREM1 GRB2 associated regulator of MAPK1 subtype 1 -0.0085731
MALT1 MALT1 paracaspase -0.00854736
TACSTD2 tumor-associated calcium signal transducer 2 -0.00848778
AQP1 aquaporin 1 (Colton blood group) -0.00847527
CLTB clathrin, light chain B -0.00845986
TNIP1 TNFAIP3 interacting protein 1 -0.00841187
SASH1 SAM and SH3 domain containing 1 -0.0084103
KRT17 keratin 17, type I -0.00840961
MBNL2 muscleblind-like splicing regulator 2 -0.00840642
MAST4 microtubule associated serine/threonine kinase family member 4 -0.00839048
ECPAS Ecm29 proteasome adaptor and scaffold -0.0083372
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 -0.00833399
PLAAT3 phospholipase A and acyltransferase 3 -0.00831335
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II -0.00830307
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae) -0.00827314
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -0.0082695
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 -0.0082541
IGLL1 immunoglobulin lambda-like polypeptide 1 -0.00823071
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) -0.00821151
IRF7 interferon regulatory factor 7 -0.00818594
MID1 midline 1 -0.00818043
MFAP3L microfibrillar-associated protein 3-like -0.00816157
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6 -0.00812181
CYB5R2 cytochrome b5 reductase 2 -0.00811112
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 -0.00808919
KYNU kynureninase -0.00808895
FBLN5 fibulin 5 -0.00807964
LAMA3 laminin, alpha 3 -0.00806388
LYPD3 LY6/PLAUR domain containing 3 -0.00804602
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 -0.00803277
ISG20 interferon stimulated exonuclease gene 20kDa -0.00802576
IFI44L interferon-induced protein 44-like -0.00801762
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) -0.00800921
KAZN kazrin, periplakin interacting protein -0.00800288
GSTP1 glutathione S-transferase pi 1 -0.0080009
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa -0.00794981
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -0.00794728
GABARAPL1 GABA(A) receptor-associated protein like 1 -0.00794701
COBL cordon-bleu WH2 repeat protein -0.00793228
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A -0.00791991
GRIA2 glutamate receptor, ionotropic, AMPA 2 -0.00791726
FLRT3 fibronectin leucine rich transmembrane protein 3 -0.00789343
MEIS1 Meis homeobox 1 -0.00785274
ADGRG2 adhesion G protein-coupled receptor G2 -0.00781563
S100A11 S100 calcium binding protein A11 -0.0078089
LMO2 LIM domain only 2 (rhombotin-like 1) -0.00780838
BUD23 BUD23 rRNA methyltransferase and ribosome maturation factor -0.0078017
AKAP12 A kinase (PRKA) anchor protein 12 -0.00777425
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 -0.00777243
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 -0.00777097
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans) -0.00776925
OLFML2A olfactomedin-like 2A -0.00776805
PRKD2 protein kinase D2 -0.00776747
VLDLR very low density lipoprotein receptor -0.00775706
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 -0.00773526
HSPA2 heat shock 70kDa protein 2 -0.00772919
HSPA6 heat shock 70kDa protein 6 (HSP70B') -0.00772779
HDLBP high density lipoprotein binding protein -0.00771768
ACAA1 acetyl-CoA acyltransferase 1 -0.0077032
CCND3 cyclin D3 -0.00769219
MATN2 matrilin 2 -0.00768363
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form) -0.00767674
TACC2 transforming, acidic coiled-coil containing protein 2 -0.00765594
EIF6 eukaryotic translation initiation factor 6 -0.00764734
RNASET2 ribonuclease T2 -0.00764458
MAP1A microtubule-associated protein 1A -0.00763418
KIAA0355 KIAA0355 -0.00763408
TTC39A tetratricopeptide repeat domain 39A -0.00761287
COG7 component of oligomeric golgi complex 7 -0.00760679
DNAJC2 DnaJ (Hsp40) homolog, subfamily C, member 2 -0.00760197
BAG1 BCL2-associated athanogene -0.00759435
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -0.00756996
BAG3 BCL2-associated athanogene 3 -0.00756985
SPRY4 sprouty homolog 4 (Drosophila) -0.00755363
GNAS GNAS complex locus -0.00755356
IFI6 interferon, alpha-inducible protein 6 -0.00754406
TMEM100 transmembrane protein 100 -0.00752352
LHFP lipoma HMGIC fusion partner -0.00752018
OXTR oxytocin receptor -0.00751044
TIMP4 TIMP metallopeptidase inhibitor 4 -0.00750443
DOCK9 dedicator of cytokinesis 9 -0.00748773
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 -0.00747477
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 -0.00746815
TNNC1 troponin C type 1 (slow) -0.00744596
WIPI1 WD repeat domain, phosphoinositide interacting 1 -0.00744464
UBR4 ubiquitin protein ligase E3 component n-recognin 4 -0.00744078
FAM107A family with sequence similarity 107, member A -0.00743398
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 -0.00741536
LAMA2 laminin, alpha 2 -0.00739333
AKR1C3 aldo-keto reductase family 1, member C3 -0.00739331
OSBPL9 oxysterol binding protein-like 9 -0.00739254
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 -0.00737087
IGF1R insulin-like growth factor 1 receptor -0.00737067
SRPX sushi-repeat containing protein, X-linked -0.00733245
SCGB2A1 secretoglobin, family 2A, member 1 -0.00732792
ZYX zyxin -0.00730338
LAMB3 laminin, beta 3 -0.00730086
COL14A1 collagen, type XIV, alpha 1 -0.00729483
IRS2 insulin receptor substrate 2 -0.00728525
SCEL sciellin -0.0072698
RABEP2 rabaptin, RAB GTPase binding effector protein 2 -0.00724424
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A -0.00724391
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 -0.00723933
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 -0.00722858
RRAGA Ras-related GTP binding A -0.00722187
SMAD3 SMAD family member 3 -0.00721586
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5 -0.0071982
VWF von Willebrand factor -0.00716579
IGF2R insulin-like growth factor 2 receptor -0.0071549
LRP4 low density lipoprotein receptor-related protein 4 -0.00714234
KLF4 Kruppel-like factor 4 (gut) -0.00713869
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 -0.0071252
APOLD1 apolipoprotein L domain containing 1 -0.00710534
MAP1LC3B microtubule-associated protein 1 light chain 3 beta -0.00710436
NKX2-2 NK2 homeobox 2 -0.00710151
TIPARP TCDD-inducible poly(ADP-ribose) polymerase -0.00710115
MAGEA1 melanoma antigen family A1 -0.00709695
TPPP3 tubulin polymerization-promoting protein family member 3 -0.00709651
NPIPB3 nuclear pore complex interacting protein family, member B3 -0.00709566
RABAC1 Rab acceptor 1 (prenylated) -0.00707543
INAVA innate immunity activator -0.00707201
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha -0.00707155
CDR2L cerebellar degeneration-related protein 2-like -0.00706606
SETD5 SET domain containing 5 -0.0070589
PDK4 pyruvate dehydrogenase kinase, isozyme 4 -0.00705641
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) -0.00705001
TFF1 trefoil factor 1 -0.0070368
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 -0.00703303
KRT14 keratin 14, type I -0.00702126
PSCA prostate stem cell antigen -0.00700496
VPREB1 pre-B lymphocyte 1 -0.00699581
CHMP2A charged multivesicular body protein 2A -0.0069944
GAB2 GRB2-associated binding protein 2 -0.00698296
BAZ2B bromodomain adjacent to zinc finger domain, 2B -0.00698013
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 -0.00696966
TFPI2 tissue factor pathway inhibitor 2 -0.00695124
KLK11 kallikrein-related peptidase 11 -0.00692913
PLK2 polo-like kinase 2 -0.00692044
PODXL podocalyxin-like -0.00691392
COL9A3 collagen, type IX, alpha 3 -0.00689806
NEFH neurofilament, heavy polypeptide -0.0068963
TUFT1 tuftelin 1 -0.00686976
ACTA2 actin, alpha 2, smooth muscle, aorta -0.00686506
QPCT glutaminyl-peptide cyclotransferase -0.00686116
KANK1 KN motif and ankyrin repeat domains 1 -0.00685741
UBE4A ubiquitination factor E4A -0.00684948
FA2H fatty acid 2-hydroxylase -0.00683765