PRC1 complex Gene Set
Dataset
GO Cellular Component Annotations 2025
Category
structural or functional annotations
Type
cellular component
Description
A multiprotein complex that mediates monoubiquitination of lysine residues of histone H2A (lysine-118 in Drosophila or lysine-119 in mammals). The complex is required for stable long-term maintenance of transcriptionally repressed states and is involved in chromatin remodeling. (Gene Ontology , GO_0035102 )
External Link
http://amigo.geneontology.org/amigo/term/GO:0035102
Similar Terms
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Genes
18 proteins localized to the PRC1 complex cellular component from the curated GO Cellular Component Annotations 2025 dataset.
Symbol
Name
CBX2
chromobox homolog 2
CBX4
chromobox homolog 4
CBX6
chromobox homolog 6
CBX7
chromobox homolog 7
CBX8
chromobox homolog 8
COMMD3-BMI1
COMMD3-BMI1 readthrough
PCGF1
polycomb group ring finger 1
PCGF2
polycomb group ring finger 2
PCGF3
polycomb group ring finger 3
PCGF5
polycomb group ring finger 5
PCGF6
polycomb group ring finger 6
PHC1
polyhomeotic homolog 1 (Drosophila)
PHC2
polyhomeotic homolog 2 (Drosophila)
PHC3
polyhomeotic homolog 3 (Drosophila)
RING1
ring finger protein 1
RNF2
ring finger protein 2
SAMD11
sterile alpha motif domain containing 11
SAMD7
sterile alpha motif domain containing 7
