| Dataset | MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | gene perturbation identified as [gene symbol]_[perturbation or condition] (Molecular Signatures Database) |
| External Link | http://www.broadinstitute.org/gsea/msigdb/cards/PRC2_SUZ12_UP.V1_UP |
| Similar Terms | |
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379 genes differentially expressed following the PRC2_SUZ12_UP.V1 gene perturbation from the MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations dataset.
| Symbol | Name |
|---|---|
| ACP5 | acid phosphatase 5, tartrate resistant |
| ACVRL1 | activin A receptor type II-like 1 |
| ADAMTS7 | ADAM metallopeptidase with thrombospondin type 1 motif, 7 |
| ADCK4 | aarF domain containing kinase 4 |
| ADCY2 | adenylate cyclase 2 (brain) |
| ADRB3 | adrenoceptor beta 3 |
| AGER | advanced glycosylation end product-specific receptor |
| AGO2 | argonaute RISC catalytic component 2 |
| AIM1L | absent in melanoma 1-like |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 |
| ALOXE3 | arachidonate lipoxygenase 3 |
| AMBP | alpha-1-microglobulin/bikunin precursor |
| ANK1 | ankyrin 1, erythrocytic |
| AP1M2 | adaptor-related protein complex 1, mu 2 subunit |
| APCS | amyloid P component, serum |
| ARF1P1 | ADP-ribosylation factor 1 pseudogene 1 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ARRB2 | arrestin, beta 2 |
| ARSD | arylsulfatase D |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) |
| ATG2A | autophagy related 2A |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 |
| BBC3 | BCL2 binding component 3 |
| BCL2L14 | BCL2-like 14 (apoptosis facilitator) |
| BPNT1 | 3'(2'), 5'-bisphosphate nucleotidase 1 |
| BTBD7 | BTB (POZ) domain containing 7 |
| C22ORF31 | chromosome 22 open reading frame 31 |
| CA7 | carbonic anhydrase VII |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 |
| CACNG2 | calcium channel, voltage-dependent, gamma subunit 2 |
| CBFA2T3 | core-binding factor, runt domain, alpha subunit 2; translocated to, 3 |
| CCL19 | chemokine (C-C motif) ligand 19 |
| CCNE1 | cyclin E1 |
| CD1B | CD1b molecule |
| CD1D | CD1d molecule |
| CD22 | CD22 molecule |
| CD247 | CD247 molecule |
| CFAP70 | cilia and flagella associated protein 70 |
| CGA | glycoprotein hormones, alpha polypeptide |
| CHEK1 | checkpoint kinase 1 |
| CHN2 | chimerin 2 |
| CHRNA6 | cholinergic receptor, nicotinic, alpha 6 (neuronal) |
| CIB1 | calcium and integrin binding 1 (calmyrin) |
| CLDN14 | claudin 14 |
| CLEC10A | C-type lectin domain family 10, member A |
| CORO1A | coronin, actin binding protein, 1A |
| CRISP1 | cysteine-rich secretory protein 1 |
| CXORF56 | chromosome X open reading frame 56 |
| DCC | DCC netrin 1 receptor |
| DCSTAMP | dendrocyte expressed seven transmembrane protein |
| DCX | doublecortin |
| DEFB126 | defensin, beta 126 |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 |
| DNAI1 | dynein, axonemal, intermediate chain 1 |
| DRP2 | dystrophin related protein 2 |
| EFNA5 | ephrin-A5 |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| EPHX2 | epoxide hydrolase 2, cytoplasmic |
| EPPK1 | epiplakin 1 |
| EVPL | envoplakin |
| FGA | fibrinogen alpha chain |
| FMO6P | flavin containing monooxygenase 6 pseudogene |
| FOXJ1 | forkhead box J1 |
| FRMD8 | FERM domain containing 8 |
| FXYD1 | FXYD domain containing ion transport regulator 1 |
| GAS8-AS1 | GAS8 antisense RNA 1 |
| GLRA2 | glycine receptor, alpha 2 |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) |
| GNGT2 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2 |
| GP9 | glycoprotein IX (platelet) |
| GUCY1B3 | guanylate cyclase 1, soluble, beta 3 |
| HAPLN2 | hyaluronan and proteoglycan link protein 2 |
| HAUS5 | HAUS augmin-like complex, subunit 5 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
| HOXA10 | homeobox A10 |
| HOXB1 | homeobox B1 |
| HOXC5 | homeobox C5 |
| HOXD11 | homeobox D11 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 |
| HYAL1 | hyaluronoglucosaminidase 1 |
| IGKV3D-15 | immunoglobulin kappa variable 3D-15 (gene/pseudogene) |
| IGLL1 | immunoglobulin lambda-like polypeptide 1 |
| IL10RA | interleukin 10 receptor, alpha |
| IL1RN | interleukin 1 receptor antagonist |
| IL23A | interleukin 23, alpha subunit p19 |
| IMPG2 | interphotoreceptor matrix proteoglycan 2 |
| KALRN | kalirin, RhoGEF kinase |
| KAT8 | K(lysine) acetyltransferase 8 |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 |
| KCNMB2 | potassium channel subfamily M regulatory beta subunit 2 |
| KLF15 | Kruppel-like factor 15 |
| KLHL11 | kelch-like family member 11 |
| KLHL23 | kelch-like family member 23 |
| KRT3 | keratin 3, type II |
| KXD1 | KxDL motif containing 1 |
| LDB2 | LIM domain binding 2 |
| LHX6 | LIM homeobox 6 |
| LILRA3 | leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3 |
| LINC00588 | long intergenic non-protein coding RNA 588 |
| LINC01558 | long intergenic non-protein coding RNA 1558 |
| LMNB2 | lamin B2 |
| LMOD1 | leiomodin 1 (smooth muscle) |
| LOC100288903 | |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 |
| LRP5L | low density lipoprotein receptor-related protein 5-like |
| LRRC61 | leucine rich repeat containing 61 |
| MAP1LC3C | microtubule-associated protein 1 light chain 3 gamma |
| MAP2K4 | mitogen-activated protein kinase kinase 4 |
| MAPT | microtubule-associated protein tau |
| MARK1 | MAP/microtubule affinity-regulating kinase 1 |
| MC5R | melanocortin 5 receptor |
| MED20 | mediator complex subunit 20 |
| MEIS2 | Meis homeobox 2 |
| MYF6 | myogenic factor 6 (herculin) |
| MYH13 | myosin, heavy chain 13, skeletal muscle |
| MYOM1 | myomesin 1 |
| NAA10 | N(alpha)-acetyltransferase 10, NatA catalytic subunit |
| NDUFC1 | NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa |
| NLGN1 | neuroligin 1 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NPY | neuropeptide Y |
| NPY2R | neuropeptide Y receptor Y2 |
| ONECUT2 | one cut homeobox 2 |
| OPCML | opioid binding protein/cell adhesion molecule-like |
| OR10J1 | olfactory receptor, family 10, subfamily J, member 1 |
| OR52A1 | olfactory receptor, family 52, subfamily A, member 1 |
| OR6A2 | olfactory receptor, family 6, subfamily A, member 2 |
| ORC1 | origin recognition complex, subunit 1 |
| P2RY10 | purinergic receptor P2Y, G-protein coupled, 10 |
| PARK2 | parkin RBR E3 ubiquitin protein ligase |
| PAX1 | paired box 1 |
| PF4 | platelet factor 4 |
| PGAP1 | post-GPI attachment to proteins 1 |
| PGK2 | phosphoglycerate kinase 2 |
| PHOX2B | paired-like homeobox 2b |
| PKP1 | plakophilin 1 |
| PNPLA3 | patatin-like phospholipase domain containing 3 |
| POLA2 | polymerase (DNA directed), alpha 2, accessory subunit |
| PRSS8 | protease, serine, 8 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| PTPRO | protein tyrosine phosphatase, receptor type, O |
| PTTG2 | pituitary tumor-transforming 2 |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| RAD54L | RAD54-like (S. cerevisiae) |
| RAVER2 | ribonucleoprotein, PTB-binding 2 |
| RECQL4 | RecQ protein-like 4 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) |
| RITA1 | RBPJ interacting and tubulin associated 1 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 |
| RPL37A | ribosomal protein L37a |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
| RUNDC3A | RUN domain containing 3A |
| SCHIP1 | schwannomin interacting protein 1 |
| SDCCAG3 | serologically defined colon cancer antigen 3 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 |
| SHPRH | SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase |
| SLC12A5 | solute carrier family 12 (potassium/chloride transporter), member 5 |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SLC17A3 | solute carrier family 17 (organic anion transporter), member 3 |
| SLC35D1 | solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 |
| SLC4A8 | solute carrier family 4, sodium bicarbonate cotransporter, member 8 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 |
| SLC7A6 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 6 |
| SLITRK3 | SLIT and NTRK-like family, member 3 |
| SOAT2 | sterol O-acyltransferase 2 |
| SRD5A2 | steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) |
| SRSF11 | serine/arginine-rich splicing factor 11 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 |
| STAU2 | staufen double-stranded RNA binding protein 2 |
| STXBP2 | syntaxin binding protein 2 |
| SUZ12 | SUZ12 polycomb repressive complex 2 subunit |
| SYN3 | synapsin III |
| T | T, brachyury homolog (mouse) |
| TACR1 | tachykinin receptor 1 |
| TCAP | titin-cap |
| TFEC | transcription factor EC |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 |
| TM4SF20 | transmembrane 4 L six family member 20 |
| TNNT2 | troponin T type 2 (cardiac) |
| TRAC | T cell receptor alpha constant |
| TSPAN12 | tetraspanin 12 |
| UBQLN3 | ubiquilin 3 |
| UPK1A | uroplakin 1A |
| USP2 | ubiquitin specific peptidase 2 |
| WFDC1 | WAP four-disulfide core domain 1 |
| WRN | Werner syndrome, RecQ helicase-like |
| ZIC4 | Zic family member 4 |
| ZNF695 | zinc finger protein 695 |
| ZNF696 | zinc finger protein 696 |
| ZWILCH | zwilch kinetochore protein |
| Symbol | Name |
|---|---|
| AATK | apoptosis-associated tyrosine kinase |
| ACAP1 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 |
| ACE | angiotensin I converting enzyme |
| ACTA1 | actin, alpha 1, skeletal muscle |
| ACTL8 | actin-like 8 |
| ADIRF | adipogenesis regulatory factor |
| AGO4 | argonaute RISC catalytic component 4 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 |
| ALX4 | ALX homeobox 4 |
| ANKRD46 | ankyrin repeat domain 46 |
| ANXA2P3 | annexin A2 pseudogene 3 |
| AOC4P | amine oxidase, copper containing 4, pseudogene |
| ARL4C | ADP-ribosylation factor-like 4C |
| ATXN1 | ataxin 1 |
| BFSP1 | beaded filament structural protein 1, filensin |
| BMP3 | bone morphogenetic protein 3 |
| BRDT | bromodomain, testis-specific |
| BTN3A2 | butyrophilin, subfamily 3, member A2 |
| C1ORF21 | chromosome 1 open reading frame 21 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| CA11 | carbonic anhydrase XI |
| CA6 | carbonic anhydrase VI |
| CAB39L | calcium binding protein 39-like |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 |
| CALML4 | calmodulin-like 4 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CBX7 | chromobox homolog 7 |
| CBX8 | chromobox homolog 8 |
| CCDC87 | coiled-coil domain containing 87 |
| CCK | cholecystokinin |
| CCL18 | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) |
| CCNK | cyclin K |
| CCNT1 | cyclin T1 |
| CD70 | CD70 molecule |
| CDADC1 | cytidine and dCMP deaminase domain containing 1 |
| CFB | complement factor B |
| CH25H | cholesterol 25-hydroxylase |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
| CIDEA | cell death-inducing DFFA-like effector a |
| CLEC4E | C-type lectin domain family 4, member E |
| CNPY4 | canopy FGF signaling regulator 4 |
| COCH | cochlin |
| COL13A1 | collagen, type XIII, alpha 1 |
| CTSS | cathepsin S |
| CXCR3 | chemokine (C-X-C motif) receptor 3 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| CYP4F12 | cytochrome P450, family 4, subfamily F, polypeptide 12 |
| DACH1 | dachshund family transcription factor 1 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 |
| DCP2 | decapping mRNA 2 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 |
| DOK2 | docking protein 2, 56kDa |
| DYNC2LI1 | dynein, cytoplasmic 2, light intermediate chain 1 |
| ECM2 | extracellular matrix protein 2, female organ and adipocyte specific |
| EDN1 | endothelin 1 |
| ELANE | elastase, neutrophil expressed |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| ERO1L | ERO1-like (S. cerevisiae) |
| ETV4 | ets variant 4 |
| FAM182B | family with sequence similarity 182, member B |
| FAT2 | FAT atypical cadherin 2 |
| FCHO1 | FCH domain only 1 |
| FCN2 | ficolin (collagen/fibrinogen domain containing lectin) 2 |
| FGF6 | fibroblast growth factor 6 |
| FGF9 | fibroblast growth factor 9 |
| FMNL1 | formin-like 1 |
| FOLR3 | folate receptor 3 (gamma) |
| GAB2 | GRB2-associated binding protein 2 |
| GAD2 | glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) |
| GATA1 | GATA binding protein 1 (globin transcription factor 1) |
| GGT5 | gamma-glutamyltransferase 5 |
| GIMAP4 | GTPase, IMAP family member 4 |
| GMIP | GEM interacting protein |
| GPC6 | glypican 6 |
| GRIN2C | glutamate receptor, ionotropic, N-methyl D-aspartate 2C |
| GRP | gastrin-releasing peptide |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 |
| HBEGF | heparin-binding EGF-like growth factor |
| HIGD1B | HIG1 hypoxia inducible domain family, member 1B |
| HR | hair growth associated |
| IFNA1 | interferon, alpha 1 |
| IGLL3P | immunoglobulin lambda-like polypeptide 3, pseudogene |
| IL1RL2 | interleukin 1 receptor-like 2 |
| IPCEF1 | interaction protein for cytohesin exchange factors 1 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KIAA0319L | KIAA0319-like |
| KIAA1024 | KIAA1024 |
| KRI1 | KRI1 homolog (S. cerevisiae) |
| KRT15 | keratin 15, type I |
| KRT81 | keratin 81, type II |
| LCAT | lecithin-cholesterol acyltransferase |
| LCE2B | late cornified envelope 2B |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LOC155060 | AI894139 pseudogene |
| LYPD1 | LY6/PLAUR domain containing 1 |
| MCTP1 | multiple C2 domains, transmembrane 1 |
| MRS2 | MRS2 magnesium transporter |
| MT4 | metallothionein 4 |
| MTMR10 | myotubularin related protein 10 |
| MTRF1 | mitochondrial translational release factor 1 |
| MYL3 | myosin, light chain 3, alkali; ventricular, skeletal, slow |
| MYT1 | myelin transcription factor 1 |
| NEIL1 | nei endonuclease VIII-like 1 (E. coli) |
| NGB | neuroglobin |
| NKX6-1 | NK6 homeobox 1 |
| NMRK2 | nicotinamide riboside kinase 2 |
| NPY4R | neuropeptide Y receptor Y4 |
| NR0B2 | nuclear receptor subfamily 0, group B, member 2 |
| NUPL1 | nucleoporin like 1 |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| OR7A10 | olfactory receptor, family 7, subfamily A, member 10 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| OSTM1 | osteopetrosis associated transmembrane protein 1 |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
| PAQR6 | progestin and adipoQ receptor family member VI |
| PCBP3 | poly(rC) binding protein 3 |
| PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor |
| PDE6A | phosphodiesterase 6A, cGMP-specific, rod, alpha |
| PKD2L1 | polycystic kidney disease 2-like 1 |
| PLEK2 | pleckstrin 2 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 |
| POLM | polymerase (DNA directed), mu |
| POMT2 | protein-O-mannosyltransferase 2 |
| POU2F1 | POU class 2 homeobox 1 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 |
| PPIEL | peptidylprolyl isomerase E-like pseudogene |
| PRKG2 | protein kinase, cGMP-dependent, type II |
| PRKY | protein kinase, Y-linked, pseudogene |
| PRSS50 | protease, serine, 50 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 |
| PTCD2 | pentatricopeptide repeat domain 2 |
| PTGIR | prostaglandin I2 (prostacyclin) receptor (IP) |
| RBM4 | RNA binding motif protein 4 |
| REST | RE1-silencing transcription factor |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| RPL3L | ribosomal protein L3-like |
| SCG5 | secretogranin V |
| SCTR | secretin receptor |
| SEMA3E | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
| SETBP1 | SET binding protein 1 |
| SLC13A3 | solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 |
| SLC15A3 | solute carrier family 15 (oligopeptide transporter), member 3 |
| SLC39A2 | solute carrier family 39 (zinc transporter), member 2 |
| SLC6A15 | solute carrier family 6 (neutral amino acid transporter), member 15 |
| SLC6A9 | solute carrier family 6 (neurotransmitter transporter, glycine), member 9 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 |
| SLPI | secretory leukocyte peptidase inhibitor |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SPIB | Spi-B transcription factor (Spi-1/PU.1 related) |
| SPTB | spectrin, beta, erythrocytic |
| SRPK3 | SRSF protein kinase 3 |
| SST | somatostatin |
| ST18 | suppression of tumorigenicity 18, zinc finger |
| STAB2 | stabilin 2 |
| STAT5A | signal transducer and activator of transcription 5A |
| TAS2R13 | taste receptor, type 2, member 13 |
| TET3 | tet methylcytosine dioxygenase 3 |
| THNSL2 | threonine synthase-like 2 (S. cerevisiae) |
| TMEM187 | transmembrane protein 187 |
| TMEM245 | transmembrane protein 245 |
| TNFRSF1B | tumor necrosis factor receptor superfamily, member 1B |
| TOM1L2 | target of myb1-like 2 (chicken) |
| TRAF3IP1 | TNF receptor-associated factor 3 interacting protein 1 |
| TRIM58 | tripartite motif containing 58 |
| TRPC6 | transient receptor potential cation channel, subfamily C, member 6 |
| UCP1 | uncoupling protein 1 (mitochondrial, proton carrier) |
| UPK3B | uroplakin 3B |
| USP46 | ubiquitin specific peptidase 46 |
| VILL | villin-like |
| WDR25 | WD repeat domain 25 |
| XK | X-linked Kx blood group |
| XPNPEP2 | X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound |
| ZNF177 | zinc finger protein 177 |
| ZNF208 | zinc finger protein 208 |
| ZNF324 | zinc finger protein 324 |
| ZNF471 | zinc finger protein 471 |
| ZNF550 | zinc finger protein 550 |
| ZNF76 | zinc finger protein 76 |
| ZRSR1 | zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 1 |
