PRDM1 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description PR domain containing 1, with ZNF domain|This gene encodes a protein that acts as a repressor of beta-interferon gene expression. The protein binds specifically to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. Transcription of this gene increases upon virus induction. Two alternatively spliced transcript variants that encode different isoforms have been reported. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 639)
External Link https://ncbi.nlm.nih.gov/gene/639
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Genes

499 genes differentially expressed following the PRDM1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
SNCA synuclein, alpha (non A4 component of amyloid precursor) 0.020286
AQP3 aquaporin 3 (Gill blood group) 0.0192223
KYNU kynureninase 0.018434
XIC X chromosome inactivation center 0.0147358
TFF1 trefoil factor 1 0.0129218
PI3 peptidase inhibitor 3, skin-derived 0.0125917
SAT1 spermidine/spermine N1-acetyltransferase 1 0.0125771
LTF lactotransferrin 0.0125487
RBM34 RNA binding motif protein 34 0.0121426
TARP TCR gamma alternate reading frame protein 0.0120354
TARBP1 TAR (HIV-1) RNA binding protein 1 0.0119603
GNAS GNAS complex locus 0.0116502
SLPI secretory leukocyte peptidase inhibitor 0.0116257
ABLIM1 actin binding LIM protein 1 0.0112717
PLAUR plasminogen activator, urokinase receptor 0.0111124
CXCL8 chemokine (C-X-C motif) ligand 8 0.0108475
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 0.0107521
CLTB clathrin, light chain B 0.0105301
KLRK1 killer cell lectin-like receptor subfamily K, member 1 0.0105171
KRT6A keratin 6A, type II 0.0104306
GPM6B glycoprotein M6B 0.0103058
S100A7 S100 calcium binding protein A7 0.0102544
S100A9 S100 calcium binding protein A9 0.00985676
KRT13 keratin 13, type I 0.00979727
KRT5 keratin 5, type II 0.00973667
ALOX5AP arachidonate 5-lipoxygenase-activating protein 0.00971867
CXCL5 chemokine (C-X-C motif) ligand 5 0.00969587
FCGBP Fc fragment of IgG binding protein 0.00962816
XPO7 exportin 7 0.00960105
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B 0.00954056
IFI27 interferon, alpha-inducible protein 27 0.0095211
WDR7 WD repeat domain 7 0.00949898
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 0.00947637
S100A8 S100 calcium binding protein A8 0.0094705
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) 0.00943151
NEBL nebulette 0.00941831
AHSP alpha hemoglobin stabilizing protein 0.00929982
C3 complement component 3 0.0092601
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.00919024
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 0.00918715
LCN2 lipocalin 2 0.00915609
CX3CR1 chemokine (C-X3-C motif) receptor 1 0.00892378
GREB1 growth regulation by estrogen in breast cancer 1 0.00889907
MAL mal, T-cell differentiation protein 0.0088973
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.00886875
SPRR3 small proline-rich protein 3 0.00885961
BHLHE41 basic helix-loop-helix family, member e41 0.00877809
LYPD3 LY6/PLAUR domain containing 3 0.00877086
ABHD4 abhydrolase domain containing 4 0.00869719
MATN2 matrilin 2 0.00868205
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.0086776
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 0.00865865
ANXA1 annexin A1 0.00864283
BCL2A1 BCL2-related protein A1 0.00862596
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 0.00859056
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.00848582
HBD hemoglobin, delta 0.00847352
HSPA1A heat shock 70kDa protein 1A 0.00846445
PDZK1IP1 PDZK1 interacting protein 1 0.00846138
C5AR1 complement component 5a receptor 1 0.00842301
ALAS2 5'-aminolevulinate synthase 2 0.00834742
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.00834312
FOSL2 FOS-like antigen 2 0.00833277
FABP7 fatty acid binding protein 7, brain 0.00832536
PLIN2 perilipin 2 0.00829218
CSTA cystatin A (stefin A) 0.0082586
CXADR coxsackie virus and adenovirus receptor 0.00819712
TRIM29 tripartite motif containing 29 0.00806698
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 0.00806197
MCL1 myeloid cell leukemia 1 0.00798873
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 0.00796186
SELE selectin E 0.00793337
LRP4 low density lipoprotein receptor-related protein 4 0.00791523
BLVRB biliverdin reductase B 0.00789837
S100A10 S100 calcium binding protein A10 0.00786694
S100P S100 calcium binding protein P 0.00782846
LAMC2 laminin, gamma 2 0.00781078
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 0.0077875
SMC1A structural maintenance of chromosomes 1A 0.00778107
ASS1 argininosuccinate synthase 1 0.00777819
AQP1 aquaporin 1 (Colton blood group) 0.00772864
CXCL12 chemokine (C-X-C motif) ligand 12 0.0077044
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) 0.00767871
OXTR oxytocin receptor 0.00763585
MUC5B mucin 5B, oligomeric mucus/gel-forming 0.00761812
PRPF4 pre-mRNA processing factor 4 0.00756494
FBP1 fructose-1,6-bisphosphatase 1 0.00756114
GPR65 G protein-coupled receptor 65 0.00754557
KLK10 kallikrein-related peptidase 10 0.00754206
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1 0.00753256
ZYX zyxin 0.00751864
RRAGA Ras-related GTP binding A 0.0074968
RIPK2 receptor-interacting serine-threonine kinase 2 0.00746765
PITX3 paired-like homeodomain 3 0.00745863
PRTN3 proteinase 3 0.00741123
CCL5 chemokine (C-C motif) ligand 5 0.00740282
NKG7 natural killer cell granule protein 7 0.00735092
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.00731494
KLRC3 killer cell lectin-like receptor subfamily C, member 3 0.00730764
SCGB2A2 secretoglobin, family 2A, member 2 0.00729692
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 0.0072887
PRAME preferentially expressed antigen in melanoma 0.0072812
PLP1 proteolipid protein 1 0.00726163
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.00725639
RAB29 RAB29, member RAS oncogene family 0.00724121
PHLDA1 pleckstrin homology-like domain, family A, member 1 0.00721804
KRT14 keratin 14, type I 0.00720699
TUBB2A tubulin, beta 2A class IIa 0.00719981
IL1RN interleukin 1 receptor antagonist 0.00719848
CST1 cystatin SN 0.00718854
GABARAPL1 GABA(A) receptor-associated protein like 1 0.00715852
RUNX3 runt-related transcription factor 3 0.00709414
B4GALT4 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 0.0070794
JMJD6 jumonji domain containing 6 0.00707053
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 0.00705235
MPDZ multiple PDZ domain protein 0.00704263
CRYAB crystallin, alpha B 0.00704101
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 0.00703976
ECPAS Ecm29 proteasome adaptor and scaffold 0.00703878
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7 0.0070125
SORD sorbitol dehydrogenase 0.00699235
CST7 cystatin F (leukocystatin) 0.00698724
COCH cochlin 0.00695548
IL2RG interleukin 2 receptor, gamma 0.00687209
VNN1 vanin 1 0.00685364
ALDH3B1 aldehyde dehydrogenase 3 family, member B1 0.00684392
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.00683628
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.00682758
STOM stomatin 0.00681579
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.00680437
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 0.00679584
CLDN10 claudin 10 0.00679462
NOLC1 nucleolar and coiled-body phosphoprotein 1 0.00678626
ISG20 interferon stimulated exonuclease gene 20kDa 0.00676691
MPO myeloperoxidase 0.00675021
CAST calpastatin 0.00671263
MT1X metallothionein 1X 0.00670916
CX3CL1 chemokine (C-X3-C motif) ligand 1 0.00670286
AOC1 amine oxidase, copper containing 1 0.00668718
FMO1 flavin containing monooxygenase 1 0.00666954
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 0.00666387
FCN1 ficolin (collagen/fibrinogen domain containing) 1 0.00663928
GM2A GM2 ganglioside activator 0.00663429
PMP2 peripheral myelin protein 2 0.00657988
TACSTD2 tumor-associated calcium signal transducer 2 0.00656883
KLF6 Kruppel-like factor 6 0.00655934
RBMS1 RNA binding motif, single stranded interacting protein 1 0.00652325
IER3 immediate early response 3 0.00648759
ABAT 4-aminobutyrate aminotransferase 0.00647493
PIP prolactin-induced protein 0.00646721
OGA O-GlcNAcase 0.00644953
NELL2 NEL-like 2 (chicken) 0.00644327
GLOD4 glyoxalase domain containing 4 0.006425
HMOX1 heme oxygenase 1 0.0064157
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) 0.00641087
CA2 carbonic anhydrase II 0.00640358
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 0.00639805
DEFB1 defensin, beta 1 0.00637975
MALT1 MALT1 paracaspase 0.00635752
KRT15 keratin 15, type I 0.00633063
LINC00623 long intergenic non-protein coding RNA 623 0.00633041
NEU1 sialidase 1 (lysosomal sialidase) 0.00631774
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.0063074
MTUS1 microtubule associated tumor suppressor 1 0.00628951
IL32 interleukin 32 0.00628746
KARS1 lysyl-tRNA synthetase 1 0.00627177
GRN granulin 0.006269
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.00625537
TADA2A transcriptional adaptor 2A 0.00624955
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 0.00624824
SH3BGR SH3 domain binding glutamate-rich protein 0.00621246
DAXX death-domain associated protein 0.00619653
TNIP1 TNFAIP3 interacting protein 1 0.00617161
SCGB2A1 secretoglobin, family 2A, member 1 0.00612612
LEF1 lymphoid enhancer-binding factor 1 0.00612323
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 0.00609618
TMEM255A transmembrane protein 255A 0.00609499
RNF10 ring finger protein 10 0.0060892
ADAM28 ADAM metallopeptidase domain 28 0.00606895
SPRR1B small proline-rich protein 1B 0.00604694
HIST1H2AC histone cluster 1, H2ac 0.00603739
ACP3 acid phosphatase 3 0.00603459
PRKCQ protein kinase C, theta 0.00603025
HSPH1 heat shock 105kDa/110kDa protein 1 0.00602872
MMP7 matrix metallopeptidase 7 0.00602324
VDAC2 voltage-dependent anion channel 2 0.00600671
PSAP prosaposin 0.00600585
RHCG Rh family, C glycoprotein 0.00600164
BAG3 BCL2-associated athanogene 3 0.00600037
ERP44 endoplasmic reticulum protein 44 0.00599983
NBN nibrin 0.00597257
POU4F1 POU class 4 homeobox 1 0.00594438
PALLD palladin, cytoskeletal associated protein 0.00592831
FN1 fibronectin 1 0.00592137
HSPA2 heat shock 70kDa protein 2 0.00589168
HSPB8 heat shock 22kDa protein 8 0.00588943
TXNL1 thioredoxin-like 1 0.00588719
MT1F metallothionein 1F 0.00587138
AP1G1 adaptor-related protein complex 1, gamma 1 subunit 0.00586659
PTCH1 patched 1 0.00586512
STC1 stanniocalcin 1 0.00586273
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1 0.00586143
ADM adrenomedullin 0.00584701
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 0.00584696
SLC31A1 solute carrier family 31 (copper transporter), member 1 0.00584555
ZFP36L2 ZFP36 ring finger protein-like 2 0.00584377
UQCRH ubiquinol-cytochrome c reductase hinge protein 0.00581595
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A 0.00581377
TREM1 triggering receptor expressed on myeloid cells 1 0.00581163
FNBP1 formin binding protein 1 0.00580041
NAMPT nicotinamide phosphoribosyltransferase 0.00580009
LY6D lymphocyte antigen 6 complex, locus D 0.00579422
IVNS1ABP influenza virus NS1A binding protein 0.00579351
DDIT4 DNA-damage-inducible transcript 4 0.00578452
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14 0.00577022
MXI1 MAX interactor 1, dimerization protein 0.00576928
MYH10 myosin, heavy chain 10, non-muscle 0.00574686
CLIC3 chloride intracellular channel 3 0.00573432
TRIM16 tripartite motif containing 16 0.00573248
SHTN1 shootin 1 0.00571738
RAD23B RAD23 homolog B (S. cerevisiae) 0.00570604
CYBB cytochrome b-245, beta polypeptide 0.00570312
AGTPBP1 ATP/GTP binding protein 1 0.00569837
FAM46C family with sequence similarity 46, member C 0.00569431
VLDLR very low density lipoprotein receptor 0.00568415
WFDC1 WAP four-disulfide core domain 1 0.00568373
SLC4A1AP solute carrier family 4 (anion exchanger), member 1, adaptor protein 0.00567681
EDN3 endothelin 3 0.00567573
PERP PERP, TP53 apoptosis effector 0.00566998
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa 0.00565109
CTSW cathepsin W 0.00564161
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 0.0056398
RNASET2 ribonuclease T2 0.00563041
CLCA2 chloride channel accessory 2 0.00562455
CLDN8 claudin 8 0.00562193
YPEL5 yippee-like 5 (Drosophila) 0.00561532
EIF5A eukaryotic translation initiation factor 5A 0.00560621
DNAJC2 DnaJ (Hsp40) homolog, subfamily C, member 2 0.00558901
OPTN optineurin 0.00557104
AIF1 allograft inflammatory factor 1 0.00556455
MMP8 matrix metallopeptidase 8 0.00555017
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.00554807
GDI2 GDP dissociation inhibitor 2 0.00554676
AFF4 AF4/FMR2 family, member 4 0.00553287
RREB1 ras responsive element binding protein 1 0.00552456
PNMA8A PNMA family member 8A 0.00549126
BMP7 bone morphogenetic protein 7 0.00547796
RANBP9 RAN binding protein 9 0.00547637
BCL3 B-cell CLL/lymphoma 3 0.00547407
CTSS cathepsin S 0.00546909

decreased expression

Symbol Name Standardized Value
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.0248782
KDM5D lysine (K)-specific demethylase 5D -0.0161759
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -0.0156334
SSBP2 single-stranded DNA binding protein 2 -0.0152278
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 -0.0146772
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -0.0134979
GNG11 guanine nucleotide binding protein (G protein), gamma 11 -0.0130047
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) -0.0126298
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -0.010923
PENK proenkephalin -0.0106434
TPSAB1 tryptase alpha/beta 1 -0.0105983
DPYSL2 dihydropyrimidinase-like 2 -0.00999545
FAM3C family with sequence similarity 3, member C -0.00984648
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked -0.0098185
PDGFRA platelet-derived growth factor receptor, alpha polypeptide -0.00977838
COMP cartilage oligomeric matrix protein -0.00963646
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -0.00949438
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) -0.00946311
BTBD3 BTB (POZ) domain containing 3 -0.00934228
PEG10 paternally expressed 10 -0.00930907
PPP1R3C protein phosphatase 1, regulatory subunit 3C -0.00929014
FST follistatin -0.0092718
CPB1 carboxypeptidase B1 (tissue) -0.00922306
PLK1 polo-like kinase 1 -0.00887268
PHACTR2 phosphatase and actin regulator 2 -0.00886069
NPM3 nucleophosmin/nucleoplasmin 3 -0.0088299
MTCL1 microtubule crosslinking factor 1 -0.00874433
CIAO3 cytosolic iron-sulfur assembly component 3 -0.00871659
STK39 serine threonine kinase 39 -0.00849288
EFNB2 ephrin-B2 -0.00848792
CRLF1 cytokine receptor-like factor 1 -0.00842617
FRZB frizzled-related protein -0.00842313
ADGRF5 adhesion G protein-coupled receptor F5 -0.00837081
CNN3 calponin 3, acidic -0.00833882
TPPP3 tubulin polymerization-promoting protein family member 3 -0.00831598
MRPL12 mitochondrial ribosomal protein L12 -0.00826788
GLS glutaminase -0.00819207
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) -0.00814158
RAMP1 receptor (G protein-coupled) activity modifying protein 1 -0.00805692
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 -0.00802231
THAP12 THAP domain containing 12 -0.00798021
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 -0.00791162
CCDC92 coiled-coil domain containing 92 -0.00784459
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 -0.00783065
HNMT histamine N-methyltransferase -0.00780281
ELN elastin -0.00778352
TXLNA taxilin alpha -0.00776646
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 -0.00773947
NINJ2 ninjurin 2 -0.00770347
MSANTD2 Myb/SANT-like DNA-binding domain containing 2 -0.00769156
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.00757359
SPINK1 serine peptidase inhibitor, Kazal type 1 -0.00755819
FKBP1B FK506 binding protein 1B, 12.6 kDa -0.007551
AKAP8 A kinase (PRKA) anchor protein 8 -0.00754662
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 -0.00754588
TMEM106C transmembrane protein 106C -0.00753991
SPTAN1 spectrin, alpha, non-erythrocytic 1 -0.00752244
METRN meteorin, glial cell differentiation regulator -0.00749962
INSIG1 insulin induced gene 1 -0.00746719
ADAM9 ADAM metallopeptidase domain 9 -0.00744517
PLXNA2 plexin A2 -0.00744457
RBM3 RNA binding motif (RNP1, RRM) protein 3 -0.00742954
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 -0.00741968
PMP22 peripheral myelin protein 22 -0.00740324
C4BPA complement component 4 binding protein, alpha -0.00738799
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3 -0.00729878
SFTPB surfactant protein B -0.00727374
HMGB3 high mobility group box 3 -0.00727374
FBLN1 fibulin 1 -0.00724662
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide -0.00723403
CIT citron rho-interacting serine/threonine kinase -0.00722189
RHOBTB3 Rho-related BTB domain containing 3 -0.00718265
BAD BCL2-associated agonist of cell death -0.00715279
SMYD3 SET and MYND domain containing 3 -0.00715207
MB myoglobin -0.00713106
TOX3 TOX high mobility group box family member 3 -0.0071237
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 -0.00709281
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 -0.00708573
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa -0.00706558
KRAS Kirsten rat sarcoma viral oncogene homolog -0.00706148
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -0.00702541
CD320 CD320 molecule -0.00701268
RAPSN receptor-associated protein of the synapse -0.00699227
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like) -0.00697876
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) -0.00695446
TMEM126B transmembrane protein 126B -0.00695345
CXCL9 chemokine (C-X-C motif) ligand 9 -0.00692743
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase -0.0068921
LEPR leptin receptor -0.0068787
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -0.00687783
PTK2 protein tyrosine kinase 2 -0.00678109
SDC2 syndecan 2 -0.00675636
FOXJ1 forkhead box J1 -0.00673871
TENT4A terminal nucleotidyltransferase 4A -0.00671607
NRGN neurogranin (protein kinase C substrate, RC3) -0.00671193
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) -0.00670519
TMEM165 transmembrane protein 165 -0.0066695
NPR3 natriuretic peptide receptor 3 -0.00666474
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 -0.00664741
CENPM centromere protein M -0.00663512
RANBP1 RAN binding protein 1 -0.00661675
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) -0.0065879
CDC20 cell division cycle 20 -0.00658623
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2 -0.00657247
SGMS1 sphingomyelin synthase 1 -0.00657225
ACTL6A actin-like 6A -0.00653757
NNMT nicotinamide N-methyltransferase -0.00653025
BCAT2 branched chain amino-acid transaminase 2, mitochondrial -0.00650091
DYNLL1 dynein, light chain, LC8-type 1 -0.0064798
CD36 CD36 molecule (thrombospondin receptor) -0.00647617
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -0.00645641
ELOVL6 ELOVL fatty acid elongase 6 -0.0064562
PTP4A3 protein tyrosine phosphatase type IVA, member 3 -0.00644443
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 -0.00644337
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3 -0.00643407
MET MET proto-oncogene, receptor tyrosine kinase -0.00642284
BASP1 brain abundant, membrane attached signal protein 1 -0.00637414
ARHGAP29 Rho GTPase activating protein 29 -0.00637273
FASN fatty acid synthase -0.00636684
IFT81 intraflagellar transport 81 -0.00636271
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -0.00634643
ZNF652 zinc finger protein 652 -0.00633015
EFHC2 EF-hand domain (C-terminal) containing 2 -0.00631332
ADIRF adipogenesis regulatory factor -0.006289
SELENOF selenoprotein F -0.00624896
AK1 adenylate kinase 1 -0.00624035
SFTPC surfactant protein C -0.0062316
CCN2 cellular communication network factor 2 -0.00623082
GSTT1 glutathione S-transferase theta 1 -0.00619914
CRIP2 cysteine-rich protein 2 -0.00619256
MDFIC MyoD family inhibitor domain containing -0.00615753
CD52 CD52 molecule -0.00613521
DRAM1 DNA-damage regulated autophagy modulator 1 -0.00612681
DSE dermatan sulfate epimerase -0.00612361
LUC7L3 LUC7-like 3 (S. cerevisiae) -0.00612184
RECK reversion-inducing-cysteine-rich protein with kazal motifs -0.00609907
SLC38A1 solute carrier family 38, member 1 -0.00609486
FBN1 fibrillin 1 -0.00606367
SLIT2 slit homolog 2 (Drosophila) -0.00605339
COL2A1 collagen, type II, alpha 1 -0.00604492
LDOC1 leucine zipper, down-regulated in cancer 1 -0.00603912
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 -0.00603207
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 -0.00600896
IL7 interleukin 7 -0.00600528
APLP2 amyloid beta (A4) precursor-like protein 2 -0.00600087
PGC progastricsin (pepsinogen C) -0.00597549
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) -0.00597333
AHR aryl hydrocarbon receptor -0.00595169
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 -0.00594437
TMEM106B transmembrane protein 106B -0.00593751
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 -0.0059282
ZMIZ1 zinc finger, MIZ-type containing 1 -0.00592084
GPNMB glycoprotein (transmembrane) nmb -0.0059066
NUP160 nucleoporin 160kDa -0.00590198
TTR transthyretin -0.00588796
RACGAP1 Rac GTPase activating protein 1 -0.00587057
PHTF2 putative homeodomain transcription factor 2 -0.00587016
KCTD14 potassium channel tetramerization domain containing 14 -0.00586121
CAMK1 calcium/calmodulin-dependent protein kinase I -0.00585716
BSG basigin (Ok blood group) -0.0058395
PTGIS prostaglandin I2 (prostacyclin) synthase -0.00581534
EPHA3 EPH receptor A3 -0.00579892
DPYD dihydropyrimidine dehydrogenase -0.00579358
POU2AF1 POU class 2 associating factor 1 -0.00579011
MYO5C myosin VC -0.00578766
DPM3 dolichyl-phosphate mannosyltransferase polypeptide 3 -0.00578662
RCAN2 regulator of calcineurin 2 -0.0057799
F13A1 coagulation factor XIII, A1 polypeptide -0.00577916
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 -0.00577458
TGFBI transforming growth factor, beta-induced, 68kDa -0.00576263
TMEM70 transmembrane protein 70 -0.00576247
STAP2 signal transducing adaptor family member 2 -0.00575545
ANPEP alanyl (membrane) aminopeptidase -0.00572722
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) -0.00571925
IFT57 intraflagellar transport 57 -0.00571921
PRKCB protein kinase C, beta -0.00571891
MBOAT7 membrane bound O-acyltransferase domain containing 7 -0.00571875
DACT1 dishevelled-binding antagonist of beta-catenin 1 -0.00571841
RPA3 replication protein A3, 14kDa -0.00567834
EDIL3 EGF-like repeats and discoidin I-like domains 3 -0.00567827
FABP6 fatty acid binding protein 6, ileal -0.00566702
TIMP3 TIMP metallopeptidase inhibitor 3 -0.00566583
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 -0.00566525
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) -0.00566089
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 -0.0056544
TBL1X transducin (beta)-like 1X-linked -0.0056309
PHYH phytanoyl-CoA 2-hydroxylase -0.00561765
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2 -0.00557571
WASF1 WAS protein family, member 1 -0.00556944
CCNB2 cyclin B2 -0.0055679
RBX1 ring-box 1, E3 ubiquitin protein ligase -0.00556337
ATP5ME ATP synthase membrane subunit e -0.00556318
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein -0.00556239
MAOA monoamine oxidase A -0.00553975
SRGN serglycin -0.00553373
CREB1 cAMP responsive element binding protein 1 -0.00552691
PTMS parathymosin -0.00551623
VPREB3 pre-B lymphocyte 3 -0.00550562
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 -0.00549779
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1 -0.00549235
PRKCZ protein kinase C, zeta -0.00549128
SOCS2 suppressor of cytokine signaling 2 -0.00548978
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 -0.00548889
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -0.0054855
HOXB6 homeobox B6 -0.00544476
CDK13 cyclin-dependent kinase 13 -0.00544352
SH3GLB2 SH3-domain GRB2-like endophilin B2 -0.00543955
BST2 bone marrow stromal cell antigen 2 -0.00541361
ANGPT1 angiopoietin 1 -0.00540934
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -0.00540445
ZBTB18 zinc finger and BTB domain containing 18 -0.00539566
MEF2C myocyte enhancer factor 2C -0.00538926
SRP9 signal recognition particle 9kDa -0.00538665
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 -0.00537823
LRRC40 leucine rich repeat containing 40 -0.0053772
E2F8 E2F transcription factor 8 -0.00535062
PCGF3 polycomb group ring finger 3 -0.00534385
KCNK3 potassium channel, two pore domain subfamily K, member 3 -0.00534056
DCK deoxycytidine kinase -0.00534047
ESYT1 extended synaptotagmin-like protein 1 -0.00533012
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1 -0.00532867
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase -0.00532676
LMO3 LIM domain only 3 (rhombotin-like 2) -0.00531188
FASTKD3 FAST kinase domains 3 -0.00530869
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 -0.00530489
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1 -0.00530374
FAM13A family with sequence similarity 13, member A -0.00529909
KIF18B kinesin family member 18B -0.00526936
TCL1B T-cell leukemia/lymphoma 1B -0.00524591
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta -0.00523028
EML3 echinoderm microtubule associated protein like 3 -0.0052267
LIMCH1 LIM and calponin homology domains 1 -0.00521
TARDBP TAR DNA binding protein -0.00520351
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast) -0.0051987
TOB1 transducer of ERBB2, 1 -0.00519345
SAP30 Sin3A-associated protein, 30kDa -0.00518946
THOC6 THO complex 6 -0.00518729
EFR3A EFR3 homolog A (S. cerevisiae) -0.00516
CENPB centromere protein B, 80kDa -0.00515812
PKD2 polycystic kidney disease 2 (autosomal dominant) -0.00515287
DCXR dicarbonyl/L-xylulose reductase -0.00514729
ENG endoglin -0.00514669
WASHC4 WASH complex subunit 4 -0.00514416
SFTPD surfactant protein D -0.0051367
DIXDC1 DIX domain containing 1 -0.00513525
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 -0.00513018
PPP4R1 protein phosphatase 4, regulatory subunit 1 -0.00512918
VTCN1 V-set domain containing T cell activation inhibitor 1 -0.00512854
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.00511347