PRDM1 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description PR domain containing 1, with ZNF domain|This gene encodes a protein that acts as a repressor of beta-interferon gene expression. The protein binds specifically to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. Transcription of this gene increases upon virus induction. Two alternatively spliced transcript variants that encode different isoforms have been reported. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 639)
External Link http://www.ncbi.nlm.nih.gov/gene/639
Similar Terms
Downloads & Tools

Genes

23 interacting proteins for PRDM1 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
AES amino-terminal enhancer of split
ATXN1 ataxin 1
CDC37 cell division cycle 37
EHMT2 euchromatic histone-lysine N-methyltransferase 2
ELAVL1 ELAV like RNA binding protein 1
HDAC1 histone deacetylase 1
HDAC2 histone deacetylase 2
HIST1H1A histone cluster 1, H1a
HIST2H3A histone cluster 2, H3a
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
IRF1 interferon regulatory factor 1
IRF2 interferon regulatory factor 2
IRF4 interferon regulatory factor 4
KDM1A lysine (K)-specific demethylase 1A
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
PIAS1 protein inhibitor of activated STAT, 1
PRMT5 protein arginine methyltransferase 5
PRMT7 protein arginine methyltransferase 7
SENP1 SUMO1/sentrin specific peptidase 1
SUMO1 small ubiquitin-like modifier 1
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TLE2 transducin-like enhancer of split 2