PRDX2 Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description peroxiredoxin 2|This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein plays an antioxidant protective role in cells, and it may contribute to the antiviral activity of CD8(+) T-cells. The crystal structure of this protein has been resolved to 2.7 angstroms. This protein prevents hemolytic anemia from oxidative stress by stabilizing hemoglobin, thus making this gene a therapeutic target for patients with hemolytic anemia. This protein may have a proliferative effect and play a role in cancer development or progression. Related pseudogenes have been identified on chromosomes 5, 6, 10 and 13. [provided by RefSeq, Mar 2013] (NCBI Entrez Gene Database, 7001)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_PRDX2
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Genes

31 co-expressed genes for PRDX2 from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
ADD2 adducin 2 (beta)
AHSP alpha hemoglobin stabilizing protein
ALAD aminolevulinate dehydratase
AMMECR1 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
ANK1 ankyrin 1, erythrocytic
BLVRB biliverdin reductase B
CA1 carbonic anhydrase I
CA2 carbonic anhydrase II
CTSE cathepsin E
DCAF11 DDB1 and CUL4 associated factor 11
GATA1 GATA binding protein 1 (globin transcription factor 1)
GCLM glutamate-cysteine ligase, modifier subunit
GLRX5 glutaredoxin 5
GYPC glycophorin C (Gerbich blood group)
HBD hemoglobin, delta
HBQ1 hemoglobin, theta 1
HDGF hepatoma-derived growth factor
HEBP1 heme binding protein 1
HMBS hydroxymethylbilane synthase
KEL Kell blood group, metallo-endopeptidase
KLF1 Kruppel-like factor 1 (erythroid)
MINPP1 multiple inositol-polyphosphate phosphatase 1
PPOX protoporphyrinogen oxidase
PRDX2 peroxiredoxin 2
RHAG Rh-associated glycoprotein
SPTB spectrin, beta, erythrocytic
TAL1 T-cell acute lymphocytic leukemia 1
TFRC transferrin receptor
UBAC1 UBA domain containing 1
UROD uroporphyrinogen decarboxylase
XK X-linked Kx blood group