PRDX3 Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description peroxiredoxin 3|This gene encodes a mitochondrial protein with antioxidant function. The protein is similar to the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase, and it can rescue bacterial resistance to alkylhydroperoxide in E. coli that lack the C22 subunit. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologs suggest that these genes consist of a family that is responsible for the regulation of cellular proliferation, differentiation and antioxidant functions. This family member can protect cells from oxidative stress, and it can promote cell survival in prostate cancer. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1, 3, 13 and 22. [provided by RefSeq, Oct 2014] (NCBI Entrez Gene Database, 10935)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/MORF_PRDX3
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Genes

84 co-expressed genes for PRDX3 from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
ACTR3 ARP3 actin-related protein 3 homolog (yeast)
AFG3L2 AFG3-like AAA ATPase 2
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
ALG8 ALG8, alpha-1,3-glucosyltransferase
AP2S1 adaptor-related protein complex 2, sigma 1 subunit
AP3S1 adaptor-related protein complex 3, sigma 1 subunit
ATP5D ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
ATP5H ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d
ATP5J ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
ATP5O ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
ATXN10 ataxin 10
BUB3 BUB3 mitotic checkpoint protein
CANX calnexin
CCT5 chaperonin containing TCP1, subunit 5 (epsilon)
COPS5 COP9 signalosome subunit 5
COX5A cytochrome c oxidase subunit Va
CSNK2B casein kinase 2, beta polypeptide
CYC1 cytochrome c-1
CYCS cytochrome c, somatic
DAP death-associated protein
DLD dihydrolipoamide dehydrogenase
EI24 etoposide induced 2.4
FAM120A family with sequence similarity 120A
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
G3BP2 GTPase activating protein (SH3 domain) binding protein 2
GLB1 galactosidase, beta 1
GNG5 guanine nucleotide binding protein (G protein), gamma 5
H2AFZ H2A histone family, member Z
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit
HAT1 histone acetyltransferase 1
HAX1 HCLS1 associated protein X-1
HCCS holocytochrome c synthase
HDAC2 histone deacetylase 2
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B
HSPA4 heat shock 70kDa protein 4
HSPA9 heat shock 70kDa protein 9 (mortalin)
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma
IFRD1 interferon-related developmental regulator 1
KARS lysyl-tRNA synthetase
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
LYPLA1 lysophospholipase I
MAP2K2 mitogen-activated protein kinase kinase 2
MDH1 malate dehydrogenase 1, NAD (soluble)
MRPS18B mitochondrial ribosomal protein S18B
MTDH metadherin
NDUFB3 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
NDUFC1 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa
NSDHL NAD(P) dependent steroid dehydrogenase-like
PARK7 parkinson protein 7
PDHB pyruvate dehydrogenase (lipoamide) beta
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae)
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G
PPT1 palmitoyl-protein thioesterase 1
PRDX3 peroxiredoxin 3
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
RAD23A RAD23 homolog A (S. cerevisiae)
RAD23B RAD23 homolog B (S. cerevisiae)
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SET SET nuclear proto-oncogene
SHFM1 split hand/foot malformation (ectrodactyly) type 1
SNRPE small nuclear ribonucleoprotein polypeptide E
SOD1 superoxide dismutase 1, soluble
SRP9 signal recognition particle 9kDa
SRSF1 serine/arginine-rich splicing factor 1
SSBP1 single-stranded DNA binding protein 1, mitochondrial
STARD7 StAR-related lipid transfer (START) domain containing 7
SUMO1 small ubiquitin-like modifier 1
SYPL1 synaptophysin-like 1
TCEB1 transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
TMEM106C transmembrane protein 106C
TRAPPC3 trafficking protein particle complex 3
TUFM Tu translation elongation factor, mitochondrial
UQCRC2 ubiquinol-cytochrome c reductase core protein II
VBP1 von Hippel-Lindau binding protein 1
VPS26A vacuolar protein sorting 26 homolog A (S. pombe)