PREPL Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description prolyl endopeptidase-like|The protein encoded by this gene belongs to the prolyl oligopeptidase subfamily of serine peptidases. Mutations in this gene have been associated with hypotonia-cystinuria syndrome, also known as the 2p21 deletion syndrome. Several alternatively spliced transcript variants encoding either the same or different isoforms have been described for this gene.[provided by RefSeq, Jan 2010] (NCBI Entrez Gene Database, 9581)
External Link http://www.ncbi.nlm.nih.gov/gene/9581
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Genes

234 interacting proteins for PREPL from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
ACAD11 acyl-CoA dehydrogenase family, member 11
ACTB actin, beta
ACTN1 actinin, alpha 1
ACTN3 actinin, alpha 3 (gene/pseudogene)
ACTR3 ARP3 actin-related protein 3 homolog (yeast)
AKAP9 A kinase (PRKA) anchor protein 9
ANAPC5 anaphase promoting complex subunit 5
ANKFY1 ankyrin repeat and FYVE domain containing 1
AP2A1 adaptor-related protein complex 2, alpha 1 subunit
APEH acylaminoacyl-peptide hydrolase
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa
ASB2 ankyrin repeat and SOCS box containing 2
ATG2A autophagy related 2A
ATXN7L2 ataxin 7-like 2
ATXN7L3 ataxin 7-like 3
ATXN7L3B ataxin 7-like 3B
AVP arginine vasopressin
BICD1 bicaudal D homolog 1 (Drosophila)
BRD8 bromodomain containing 8
CAPN3 calpain 3, (p94)
CCAR1 cell division cycle and apoptosis regulator 1
CCDC101 coiled-coil domain containing 101
CCDC106 coiled-coil domain containing 106
CDC16 cell division cycle 16
CDC5L cell division cycle 5-like
CGN cingulin
CHM choroideremia (Rab escort protein 1)
CLASP2 cytoplasmic linker associated protein 2
CLCF1 cardiotrophin-like cytokine factor 1
CNN1 calponin 1, basic, smooth muscle
CNOT1 CCR4-NOT transcription complex, subunit 1
CNOT10 CCR4-NOT transcription complex, subunit 10
COIL coilin
COPB2 coatomer protein complex, subunit beta 2 (beta prime)
COPG2 coatomer protein complex, subunit gamma 2
CPSF6 cleavage and polyadenylation specific factor 6, 68kDa
CPT1A carnitine palmitoyltransferase 1A (liver)
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTTN cortactin
CWC15 CWC15 spliceosome-associated protein
CWC27 CWC27 spliceosome-associated protein homolog (S. cerevisiae)
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DDX41 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41
DDX50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
DEDD death effector domain containing
DLGAP4 discs, large (Drosophila) homolog-associated protein 4
DNTTIP1 deoxynucleotidyltransferase, terminal, interacting protein 1
EDC4 enhancer of mRNA decapping 4
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
ELAVL1 ELAV like RNA binding protein 1
ELMSAN1 ELM2 and Myb/SANT-like domain containing 1
ENY2 enhancer of yellow 2 homolog (Drosophila)
EPB41L5 erythrocyte membrane protein band 4.1 like 5
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
FAM120A family with sequence similarity 120A
FAM179B family with sequence similarity 179, member B
FIP1L1 factor interacting with PAPOLA and CPSF1
FLG filaggrin
FLNB filamin B, beta
FLNC filamin C, gamma
FMR1 fragile X mental retardation 1
FTSJ3 FtsJ homolog 3 (E. coli)
GFAP glial fibrillary acidic protein
GIGYF1 GRB10 interacting GYF protein 1
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GNL2 guanine nucleotide binding protein-like 2 (nucleolar)
GNL3 guanine nucleotide binding protein-like 3 (nucleolar)
GOLGA3 golgin A3
GOLGA4 golgin A4
GSN gelsolin
GSPT1 G1 to S phase transition 1
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
GTPBP4 GTP binding protein 4
HCFC1 host cell factor C1
HCFC2 host cell factor C2
HEATR4 HEAT repeat containing 4
HIST1H1C histone cluster 1, H1c
HP1BP3 heterochromatin protein 1, binding protein 3
HR hair growth associated
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPA8 heat shock 70kDa protein 8
HTATSF1 HIV-1 Tat specific factor 1
KAT2A K(lysine) acetyltransferase 2A
KATNAL2 katanin p60 subunit A-like 2
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KIF7 kinesin family member 7
KLHL23 kelch-like family member 23
KRI1 KRI1 homolog (S. cerevisiae)
LAD1 ladinin 1
LARP1 La ribonucleoprotein domain family, member 1
LAS1L LAS1-like (S. cerevisiae)
LONP1 lon peptidase 1, mitochondrial
LRRC1 leucine rich repeat containing 1
LRRC59 leucine rich repeat containing 59
LYAR Ly1 antibody reactive
MED1 mediator complex subunit 1
MED12 mediator complex subunit 12
MED13 mediator complex subunit 13
MED14 mediator complex subunit 14
MED16 mediator complex subunit 16
MED17 mediator complex subunit 17
MED23 mediator complex subunit 23
MED24 mediator complex subunit 24
MED27 mediator complex subunit 27
MED4 mediator complex subunit 4
MRPL44 mitochondrial ribosomal protein L44
MRPL45 mitochondrial ribosomal protein L45
MRPS15 mitochondrial ribosomal protein S15
MRPS2 mitochondrial ribosomal protein S2
MRPS21 mitochondrial ribosomal protein S21
MRPS22 mitochondrial ribosomal protein S22
MRPS27 mitochondrial ribosomal protein S27
MRPS31 mitochondrial ribosomal protein S31
MRPS5 mitochondrial ribosomal protein S5
MRPS9 mitochondrial ribosomal protein S9
MTA2 metastasis associated 1 family, member 2
MYBBP1A MYB binding protein (P160) 1a
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle
MYLK2 myosin light chain kinase 2
MYO1C myosin IC
MYO3B myosin IIIB
NAT10 N-acetyltransferase 10 (GCN5-related)
NBPF8 neuroblastoma breakpoint family, member 8
NCBP1 nuclear cap binding protein subunit 1, 80kDa
NCOA3 nuclear receptor coactivator 3
NOP56 NOP56 ribonucleoprotein
NR4A1 nuclear receptor subfamily 4, group A, member 1
NRIP1 nuclear receptor interacting protein 1
NUP205 nucleoporin 205kDa
OXT oxytocin/neurophysin I prepropeptide
PABPC1L poly(A) binding protein, cytoplasmic 1-like
PABPC3 poly(A) binding protein, cytoplasmic 3
PABPC5 poly(A) binding protein, cytoplasmic 5
PBRM1 polybromo 1
PELP1 proline, glutamate and leucine rich protein 1
PES1 pescadillo ribosomal biogenesis factor 1
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4
PKP3 plakophilin 3
POFUT2 protein O-fucosyltransferase 2
PRDX3 peroxiredoxin 3
PRDX4 peroxiredoxin 4
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator
PROSER2 proline and serine rich 2
PRPF31 pre-mRNA processing factor 31
PRPH peripherin
PRRC2C proline-rich coiled-coil 2C
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
PTCD3 pentatricopeptide repeat domain 3
RALY RALY heterogeneous nuclear ribonucleoprotein
RBM10 RNA binding motif protein 10
RBM14 RNA binding motif protein 14
RBM25 RNA binding motif protein 25
RBM43 RNA binding motif protein 43
RBM47 RNA binding motif protein 47
RBMXL2 RNA binding motif protein, X-linked-like 2
RMDN3 regulator of microtubule dynamics 3
RPF2 ribosome production factor 2 homolog (S. cerevisiae)
RPL13AP3 ribosomal protein L13a pseudogene 3
RPL17 ribosomal protein L17
RPL18A ribosomal protein L18a
RPL23 ribosomal protein L23
RPL23A ribosomal protein L23a
RPL29 ribosomal protein L29
RPL32 ribosomal protein L32
RPL36 ribosomal protein L36
RPL36AL ribosomal protein L36a-like
RPL3L ribosomal protein L3-like
RPL7 ribosomal protein L7
RPL7A ribosomal protein L7a
RPLP0 ribosomal protein, large, P0
RPS11 ribosomal protein S11
RPS13 ribosomal protein S13
RPS16 ribosomal protein S16
RPS18 ribosomal protein S18
RPS24 ribosomal protein S24
RPS25 ribosomal protein S25
RPS26 ribosomal protein S26
RPS27L ribosomal protein S27-like
RPS3 ribosomal protein S3
RPS4X ribosomal protein S4, X-linked
RPS4Y1 ribosomal protein S4, Y-linked 1
RPS6 ribosomal protein S6
RPS7 ribosomal protein S7
RPS9 ribosomal protein S9
RRBP1 ribosome binding protein 1
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
RTCB RNA 2',3'-cyclic phosphate and 5'-OH ligase
SCN1A sodium channel, voltage gated, type I alpha subunit
SERBP1 SERPINE1 mRNA binding protein 1
SF3A1 splicing factor 3a, subunit 1, 120kDa
SF3B3 splicing factor 3b, subunit 3, 130kDa
SIN3A SIN3 transcription regulator family member A
SIPA1L2 signal-induced proliferation-associated 1 like 2
SIRT1 sirtuin 1
SLC7A6 solute carrier family 7 (amino acid transporter light chain, y+L system), member 6
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
SMC1A structural maintenance of chromosomes 1A
SMN2 survival of motor neuron 2, centromeric
SMTN smoothelin
SND1 staphylococcal nuclease and tudor domain containing 1
SPRR1B small proline-rich protein 1B
SRSF2 serine/arginine-rich splicing factor 2
SRSF5 serine/arginine-rich splicing factor 5
SSR1 signal sequence receptor, alpha
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae)
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
SUPT7L suppressor of Ty 7 (S. cerevisiae)-like
SYNGAP1 synaptic Ras GTPase activating protein 1
TADA1 transcriptional adaptor 1
TADA2B transcriptional adaptor 2B
TADA3 transcriptional adaptor 3
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TAF9 TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
TCOF1 Treacher Collins-Franceschetti syndrome 1
TEX10 testis expressed 10
THOC6 THO complex 6
TRIM24 tripartite motif containing 24
TRRAP transformation/transcription domain-associated protein
UBC ubiquitin C
USP22 ubiquitin specific peptidase 22
USP27X ubiquitin specific peptidase 27, X-linked
VIM vimentin
WDR18 WD repeat domain 18
WDR62 WD repeat domain 62