PRICKLE1 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description prickle homolog 1 (Drosophila)|This gene encodes a nuclear receptor that may be a negative regulator of the Wnt/beta-catenin signaling pathway. The encoded protein localizes to the nuclear membrane and has been implicated in the nuclear trafficking of the transcription repressors REST/NRSF and REST4. Mutations in this gene have been linked to progressive myoclonus epilepsy. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 3. [provided by RefSeq, Sep 2009] (NCBI Entrez Gene Database, 144165)
External Link http://www.ncbi.nlm.nih.gov/gene/144165
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86 interacting proteins for PRICKLE1 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ANXA1 annexin A1
AZGP1 alpha-2-glycoprotein 1, zinc-binding
C1ORF35 chromosome 1 open reading frame 35
CCDC85C coiled-coil domain containing 85C
CPVL carboxypeptidase, vitellogenic-like
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CSNK2B casein kinase 2, beta polypeptide
CSTA cystatin A (stefin A)
CTSD cathepsin D
DDB1 damage-specific DNA binding protein 1, 127kDa
DOCK7 dedicator of cytokinesis 7
DVL1 dishevelled segment polarity protein 1
DVL2 dishevelled segment polarity protein 2
DVL3 dishevelled segment polarity protein 3
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GDI2 GDP dissociation inhibitor 2
GGCT gamma-glutamylcyclotransferase
KCMF1 potassium channel modulatory factor 1
LRCH2 leucine-rich repeats and calponin homology (CH) domain containing 2
MCM7 minichromosome maintenance complex component 7
PARD3 par-3 family cell polarity regulator
PARD6A par-6 family cell polarity regulator alpha
PCBP1 poly(rC) binding protein 1
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPP1R13B protein phosphatase 1, regulatory subunit 13B
PRICKLE3 prickle homolog 3 (Drosophila)
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7
PSMA8 proteasome (prosome, macropain) subunit, alpha type, 8
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
PSME4 proteasome (prosome, macropain) activator subunit 4
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
RASSF10 Ras association (RalGDS/AF-6) domain family (N-terminal) member 10
RASSF7 Ras association (RalGDS/AF-6) domain family (N-terminal) member 7
RBBP4 retinoblastoma binding protein 4
S100A14 S100 calcium binding protein A14
S100A7 S100 calcium binding protein A7
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SMR3B submaxillary gland androgen regulated protein 3B
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SMURF2 SMAD specific E3 ubiquitin protein ligase 2
SPRR2E small proline-rich protein 2E
SRRM2 serine/arginine repetitive matrix 2
TP53BP2 tumor protein p53 binding protein 2
UBC ubiquitin C
USP9X ubiquitin specific peptidase 9, X-linked
VANGL1 VANGL planar cell polarity protein 1
VIP vasoactive intestinal peptide