PRKAG1 Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description protein kinase, AMP-activated, gamma 1 non-catalytic subunit|The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 5571)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/MORF_PRKAG1
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Genes

267 co-expressed genes for PRKAG1 from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
AANAT aralkylamine N-acetyltransferase
AATF apoptosis antagonizing transcription factor
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABR active BCR-related
ACTL6A actin-like 6A
ADAM15 ADAM metallopeptidase domain 15
AFG3L2 AFG3-like AAA ATPase 2
AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1
AHCYL1 adenosylhomocysteinase-like 1
AIP aryl hydrocarbon receptor interacting protein
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ALG3 ALG3, alpha-1,3- mannosyltransferase
ANKRD17 ankyrin repeat domain 17
ANXA7 annexin A7
AP3B1 adaptor-related protein complex 3, beta 1 subunit
AP3S1 adaptor-related protein complex 3, sigma 1 subunit
ARCN1 archain 1
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2
ATP11B ATPase, class VI, type 11B
ATP6V1F ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F
ATXN2 ataxin 2
ATXN2L ataxin 2-like
B4GALT3 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3
BAHD1 bromo adjacent homology domain containing 1
BCAT2 branched chain amino-acid transaminase 2, mitochondrial
BECN1 beclin 1, autophagy related
BMS1 BMS1 ribosome biogenesis factor
BPHL biphenyl hydrolase-like (serine hydrolase)
BRD3 bromodomain containing 3
BRD8 bromodomain containing 8
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CALM2 calmodulin 2 (phosphorylase kinase, delta)
CANX calnexin
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1
CAPZB capping protein (actin filament) muscle Z-line, beta
CCR9 chemokine (C-C motif) receptor 9
CCT4 chaperonin containing TCP1, subunit 4 (delta)
CDC25C cell division cycle 25C
CENPI centromere protein I
CETN3 centrin, EF-hand protein, 3
CHD3 chromodomain helicase DNA binding protein 3
CIB1 calcium and integrin binding 1 (calmyrin)
CLSTN1 calsyntenin 1
CLTC clathrin, heavy chain (Hc)
CNOT3 CCR4-NOT transcription complex, subunit 3
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase
COPS6 COP9 signalosome subunit 6
COQ9 coenzyme Q9
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous)
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa
CS citrate synthase
CSN3 casein kappa
CSNK1D casein kinase 1, delta
CSNK1G2 casein kinase 1, gamma 2
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
CTDNEP1 CTD nuclear envelope phosphatase 1
CUL4B cullin 4B
CYHR1 cysteine/histidine-rich 1
DAP3 death associated protein 3
DDB1 damage-specific DNA binding protein 1, 127kDa
DDX18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
DEXI Dexi homolog (mouse)
DGCR6 DiGeorge syndrome critical region gene 6
DHPS deoxyhypusine synthase
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7
DNAJC8 DnaJ (Hsp40) homolog, subfamily C, member 8
DOCK3 dedicator of cytokinesis 3
DPF2 D4, zinc and double PHD fingers family 2
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha)
DRG1 developmentally regulated GTP binding protein 1
DRG2 developmentally regulated GTP binding protein 2
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene
EBI3 Epstein-Barr virus induced 3
EBP emopamil binding protein (sterol isomerase)
EHBP1 EH domain binding protein 1
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa
EIF3I eukaryotic translation initiation factor 3, subunit I
EML3 echinoderm microtubule associated protein like 3
EPRS glutamyl-prolyl-tRNA synthetase
ESYT1 extended synaptotagmin-like protein 1
FAM189B family with sequence similarity 189, member B
FANCC Fanconi anemia, complementation group C
FANCG Fanconi anemia, complementation group G
FBXW11 F-box and WD repeat domain containing 11
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FEV FEV (ETS oncogene family)
FUT2 fucosyltransferase 2 (secretor status included)
GBAS glioblastoma amplified sequence
GLG1 golgi glycoprotein 1
GLUD1 glutamate dehydrogenase 1
GNL2 guanine nucleotide binding protein-like 2 (nucleolar)
GOLGA3 golgin A3
GPAA1 glycosylphosphatidylinositol anchor attachment 1
GPER1 G protein-coupled estrogen receptor 1
GRM4 glutamate receptor, metabotropic 4
GSTZ1 glutathione S-transferase zeta 1
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit
HDAC1 histone deacetylase 1
HDAC2 histone deacetylase 2
HLTF helicase-like transcription factor
HMGA2 high mobility group AT-hook 2
HMGN4 high mobility group nucleosomal binding domain 4
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1
HNRNPH2 heterogeneous nuclear ribonucleoprotein H2 (H')
HNRNPL heterogeneous nuclear ribonucleoprotein L
HSPA8 heat shock 70kDa protein 8
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
ILF2 interleukin enhancer binding factor 2
ILK integrin-linked kinase
ILVBL ilvB (bacterial acetolactate synthase)-like
INTS10 integrator complex subunit 10
KDM3B lysine (K)-specific demethylase 3B
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KIAA0195 KIAA0195
KPNA6 karyopherin alpha 6 (importin alpha 7)
KRT32 keratin 32, type I
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial)
LRPPRC leucine-rich pentatricopeptide repeat containing
LSM12 LSM12 homolog (S. cerevisiae)
LYST lysosomal trafficking regulator
MADD MAP-kinase activating death domain
MAPK3 mitogen-activated protein kinase 3
MARS methionyl-tRNA synthetase
MCFD2 multiple coagulation factor deficiency 2
MEA1 male-enhanced antigen 1
METAP1 methionyl aminopeptidase 1
MFN2 mitofusin 2
MGAT1 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MLEC malectin
MMS19 MMS19 nucleotide excision repair homolog (S. cerevisiae)
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
MPST mercaptopyruvate sulfurtransferase
MRPL28 mitochondrial ribosomal protein L28
MRPL9 mitochondrial ribosomal protein L9
MRPS18B mitochondrial ribosomal protein S18B
MTA1 metastasis associated 1
MTX1 metaxin 1
MYCBP MYC binding protein
MZF1 myeloid zinc finger 1
NAP1L4 nucleosome assembly protein 1-like 4
NCBP2 nuclear cap binding protein subunit 2, 20kDa
NCOR2 nuclear receptor corepressor 2
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
NEFL neurofilament, light polypeptide
NELFB negative elongation factor complex member B
NFRKB nuclear factor related to kappaB binding protein
NFYB nuclear transcription factor Y, beta
NIPSNAP1 nipsnap homolog 1 (C. elegans)
NONO non-POU domain containing, octamer-binding
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3
NUP188 nucleoporin 188kDa
NUP62 nucleoporin 62kDa
ODF1 outer dense fiber of sperm tails 1
OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PABPN1 poly(A) binding protein, nuclear 1
PARG poly (ADP-ribose) glycohydrolase
PARN poly(A)-specific ribonuclease
PARP2 poly (ADP-ribose) polymerase 2
PCGF1 polycomb group ring finger 1
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDXDC1 pyridoxal-dependent decarboxylase domain containing 1
PHB prohibitin
PIGC phosphatidylinositol glycan anchor biosynthesis, class C
PKMYT1 protein kinase, membrane associated tyrosine/threonine 1
PLIN3 perilipin 3
PLK1 polo-like kinase 1
PMM2 phosphomannomutase 2
PNMT phenylethanolamine N-methyltransferase
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
POLR2C polymerase (RNA) II (DNA directed) polypeptide C, 33kDa
PPP1R11 protein phosphatase 1, regulatory (inhibitor) subunit 11
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PRDX4 peroxiredoxin 4
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit
PRKCG protein kinase C, gamma
PRKCSH protein kinase C substrate 80K-H
PRPF8 pre-mRNA processing factor 8
PSG7 pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene)
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
PWP1 PWP1 homolog (S. cerevisiae)
RAB1A RAB1A, member RAS oncogene family
RABAC1 Rab acceptor 1 (prenylated)
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RENBP renin binding protein
RFC1 replication factor C (activator 1) 1, 145kDa
RING1 ring finger protein 1
RPA2 replication protein A2, 32kDa
RPN2 ribophorin II
RPRD2 regulation of nuclear pre-mRNA domain containing 2
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
RTCA RNA 3'-terminal phosphate cyclase
RTN4 reticulon 4
RUVBL2 RuvB-like AAA ATPase 2
SARS seryl-tRNA synthetase
SART3 squamous cell carcinoma antigen recognized by T cells 3
SCARB1 scavenger receptor class B, member 1
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
SEC23IP SEC23 interacting protein
SEC31A SEC31 homolog A (S. cerevisiae)
SEC61B Sec61 beta subunit
SEC62 SEC62 homolog (S. cerevisiae)
SEC63 SEC63 homolog (S. cerevisiae)
SEPT7 septin 7
SERP1 stress-associated endoplasmic reticulum protein 1
SFSWAP splicing factor, suppressor of white-apricot family
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SH2B1 SH2B adaptor protein 1
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
SLC4A2 solute carrier family 4 (anion exchanger), member 2
SMAD2 SMAD family member 2
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
SMNDC1 survival motor neuron domain containing 1
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5)
SRRT serrate, RNA effector molecule
SS18 synovial sarcoma translocation, chromosome 18
SSB Sjogren syndrome antigen B (autoantigen La)
SSR1 signal sequence receptor, alpha
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)
STK19 serine/threonine kinase 19
SUMO2 small ubiquitin-like modifier 2
SUMO4 small ubiquitin-like modifier 4
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TAF11 TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa
TAF9 TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
TBL2 transducin (beta)-like 2
TCEA1 transcription elongation factor A (SII), 1
TCOF1 Treacher Collins-Franceschetti syndrome 1
TERF2IP telomeric repeat binding factor 2, interacting protein
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1
TIMM17A translocase of inner mitochondrial membrane 17 homolog A (yeast)
TLK2 tousled-like kinase 2
TMED1 transmembrane emp24 protein transport domain containing 1
TMEM106A transmembrane protein 106A
TOMM34 translocase of outer mitochondrial membrane 34
TOR1AIP1 torsin A interacting protein 1
TP53BP1 tumor protein p53 binding protein 1
TPR translocated promoter region, nuclear basket protein
TRIP13 thyroid hormone receptor interactor 13
TSTA3 tissue specific transplantation antigen P35B
TTF1 transcription termination factor, RNA polymerase I
TXLNA taxilin alpha
UBE2A ubiquitin-conjugating enzyme E2A
UBE3C ubiquitin protein ligase E3C
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VAMP3 vesicle-associated membrane protein 3
VARS valyl-tRNA synthetase
VGLL4 vestigial-like family member 4
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae)
WAS Wiskott-Aldrich syndrome
XPO6 exportin 6
XPO7 exportin 7
YIF1A Yip1 interacting factor homolog A (S. cerevisiae)
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
ZNF134 zinc finger protein 134
ZNF271P zinc finger protein 271, pseudogene
ZNF76 zinc finger protein 76
ZNF8 zinc finger protein 8
ZNHIT3 zinc finger, HIT-type containing 3
ZPR1 ZPR1 zinc finger
ZZZ3 zinc finger, ZZ-type containing 3