PRKCA Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description protein kinase C, alpha|Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 5578)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/MORF_PRKCA
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Genes

183 co-expressed genes for PRKCA from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCB10 ATP-binding cassette, sub-family B (MDR/TAP), member 10
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ADAM20 ADAM metallopeptidase domain 20
ADAMTSL3 ADAMTS-like 3
ADGRL2 adhesion G protein-coupled receptor L2
ADRA1A adrenoceptor alpha 1A
AMMECR1 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
AOC4P amine oxidase, copper containing 4, pseudogene
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
AQP7 aquaporin 7
ATF2 activating transcription factor 2
ATP4B ATPase, H+/K+ exchanging, beta polypeptide
ATXN3 ataxin 3
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
BMP10 bone morphogenetic protein 10
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1
CADM4 cell adhesion molecule 4
CAMK4 calcium/calmodulin-dependent protein kinase IV
CAMTA1 calmodulin binding transcription activator 1
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CDC73 cell division cycle 73
CDR1 cerebellar degeneration-related protein 1, 34kDa
CEP162 centrosomal protein 162kDa
CFH complement factor H
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal)
CLCN3 chloride channel, voltage-sensitive 3
CNTN6 contactin 6
COL14A1 collagen, type XIV, alpha 1
COL19A1 collagen, type XIX, alpha 1
COL8A1 collagen, type VIII, alpha 1
COQ7 coenzyme Q7 homolog, ubiquinone (yeast)
CPB2 carboxypeptidase B2 (plasma)
CPEB3 cytoplasmic polyadenylation element binding protein 3
CRHR1 corticotropin releasing hormone receptor 1
CTRL chymotrypsin-like
CTSB cathepsin B
CXCL5 chemokine (C-X-C motif) ligand 5
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DBT dihydrolipoamide branched chain transacylase E2
DDX52 DEAD (Asp-Glu-Ala-Asp) box polypeptide 52
DMD dystrophin
DMPK dystrophia myotonica-protein kinase
DNAJC22 DnaJ (Hsp40) homolog, subfamily C, member 22
DRD1 dopamine receptor D1
EDIL3 EGF-like repeats and discoidin I-like domains 3
EPHB2 EPH receptor B2
ERCC4 excision repair cross-complementation group 4
EXOC4 exocyst complex component 4
EYA1 EYA transcriptional coactivator and phosphatase 1
F2RL1 coagulation factor II (thrombin) receptor-like 1
FAM110B family with sequence similarity 110, member B
FAM13A family with sequence similarity 13, member A
FAM153B family with sequence similarity 153, member B
FAM63B family with sequence similarity 63, member B
FBXL4 F-box and leucine-rich repeat protein 4
FLRT2 fibronectin leucine rich transmembrane protein 2
FOSL1 FOS-like antigen 1
FSHR follicle stimulating hormone receptor
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
FZD5 frizzled class receptor 5
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GCM1 glial cells missing homolog 1 (Drosophila)
GHRHR growth hormone releasing hormone receptor
GJB5 gap junction protein, beta 5, 31.1kDa
GLRA3 glycine receptor, alpha 3
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPR1 G protein-coupled receptor 1
GPR171 G protein-coupled receptor 171
GPR18 G protein-coupled receptor 18
GPR19 G protein-coupled receptor 19
GRIK1 glutamate receptor, ionotropic, kainate 1
GUCY2F guanylate cyclase 2F, retinal
HCG8 HLA complex group 8
HCRTR2 hypocretin (orexin) receptor 2
HEPH hephaestin
HNF1A HNF1 homeobox A
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IFNA1 interferon, alpha 1
IFNA10 interferon, alpha 10
IFNA14 interferon, alpha 14
IFNA2 interferon, alpha 2
IFNW1 interferon, omega 1
IGKV7-3 immunoglobulin kappa variable 7-3 (pseudogene)
IL11RA interleukin 11 receptor, alpha
IL16 interleukin 16
IL7 interleukin 7
IPO9 importin 9
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains)
ITIH3 inter-alpha-trypsin inhibitor heavy chain 3
JADE3 jade family PHD finger 3
JRKL JRK-like
KLRC4 killer cell lectin-like receptor subfamily C, member 4
KRT2 keratin 2, type II
KRT34 keratin 34, type I
LDB3 LIM domain binding 3
LECT2 leukocyte cell-derived chemotaxin 2
LGI1 leucine-rich, glioma inactivated 1
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1
LOR loricrin
LPPR4 lipid phosphate phosphatase-related protein type 4
LRP4 low density lipoprotein receptor-related protein 4
MAGEA8 melanoma antigen family A8
MAGEA9 melanoma antigen family A9
MAP2 microtubule-associated protein 2
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MC5R melanocortin 5 receptor
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MYT1 myelin transcription factor 1
NEB nebulin
NHEJ1 nonhomologous end-joining factor 1
NPFF neuropeptide FF-amide peptide precursor
NR1I2 nuclear receptor subfamily 1, group I, member 2
NR3C2 nuclear receptor subfamily 3, group C, member 2
NTNG2 netrin G2
OR10H3 olfactory receptor, family 10, subfamily H, member 3
OR2B6 olfactory receptor, family 2, subfamily B, member 6
P2RY10 purinergic receptor P2Y, G-protein coupled, 10
PART1 prostate androgen-regulated transcript 1 (non-protein coding)
PAX6 paired box 6
PCM1 pericentriolar material 1
PDE4D phosphodiesterase 4D, cAMP-specific
PDE6A phosphodiesterase 6A, cGMP-specific, rod, alpha
PGM3 phosphoglucomutase 3
PHF10 PHD finger protein 10
PHLDB1 pleckstrin homology-like domain, family B, member 1
PHOX2B paired-like homeobox 2b
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
POU6F1 POU class 6 homeobox 1
POU6F2 POU class 6 homeobox 2
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E
PRKCA protein kinase C, alpha
PSG1 pregnancy specific beta-1-glycoprotein 1
PTPN20 protein tyrosine phosphatase, non-receptor type 20
PTPRB protein tyrosine phosphatase, receptor type, B
PVR poliovirus receptor
R3HCC1L R3H domain and coiled-coil containing 1-like
RAD51D RAD51 paralog D
RB1CC1 RB1-inducible coiled-coil 1
RBMXL1 RNA binding motif protein, X-linked-like 1
RNF24 ring finger protein 24
RORB RAR-related orphan receptor B
RREB1 ras responsive element binding protein 1
RXRG retinoid X receptor, gamma
RYR3 ryanodine receptor 3
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SIX6 SIX homeobox 6
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1
SLC46A3 solute carrier family 46, member 3
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SMYD3 SET and MYND domain containing 3
SPA17 sperm autoantigenic protein 17
SPAG11B sperm associated antigen 11B
SPRR2C small proline-rich protein 2C (pseudogene)
ST8SIA1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
STAC SH3 and cysteine rich domain
SULT4A1 sulfotransferase family 4A, member 1
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
T T, brachyury homolog (mouse)
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TBX19 T-box 19
TDGF1 teratocarcinoma-derived growth factor 1
TENM4 teneurin transmembrane protein 4
THPO thrombopoietin
TLL1 tolloid-like 1
TNIK TRAF2 and NCK interacting kinase
TSSK2 testis-specific serine kinase 2
TTTY1 testis-specific transcript, Y-linked 1 (non-protein coding)
UBE4B ubiquitination factor E4B
ZBTB14 zinc finger and BTB domain containing 14
ZBTB40 zinc finger and BTB domain containing 40
ZNF132 zinc finger protein 132
ZNF141 zinc finger protein 141
ZNF157 zinc finger protein 157
ZNF202 zinc finger protein 202
ZSCAN26 zinc finger and SCAN domain containing 26