| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | protein kinase C, delta|Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. Studies both in human and mice demonstrate that this kinase is involved in B cell signaling and in the regulation of growth, apoptosis, and differentiation of a variety of cell types. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 5580) |
| External Link | https://ncbi.nlm.nih.gov/gene/5580 |
| Similar Terms | |
| Downloads & Tools |
498 genes differentially expressed following the PRKCD gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TUBB2A | tubulin, beta 2A class IIa | 0.00934343 |
| AOC1 | amine oxidase, copper containing 1 | 0.00913907 |
| CA2 | carbonic anhydrase II | 0.00891702 |
| TUBB6 | tubulin, beta 6 class V | 0.00822231 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 0.00802006 |
| CRYAB | crystallin, alpha B | 0.00759497 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 0.00745276 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.00720177 |
| CA12 | carbonic anhydrase XII | 0.00712479 |
| AK4 | adenylate kinase 4 | 0.00711629 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | 0.00699582 |
| CALB1 | calbindin 1, 28kDa | 0.00692759 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.00681357 |
| PITX3 | paired-like homeodomain 3 | 0.00674709 |
| STC2 | stanniocalcin 2 | 0.00667007 |
| BCL2A1 | BCL2-related protein A1 | 0.00653003 |
| SALL1 | spalt-like transcription factor 1 | 0.00651308 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.00650761 |
| TFF1 | trefoil factor 1 | 0.00647577 |
| LEFTY1 | left-right determination factor 1 | 0.00645032 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.00638555 |
| S100A10 | S100 calcium binding protein A10 | 0.00636012 |
| GREB1 | growth regulation by estrogen in breast cancer 1 | 0.00634335 |
| FABP7 | fatty acid binding protein 7, brain | 0.00628212 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.00620282 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | 0.00608346 |
| DEFB1 | defensin, beta 1 | 0.00601252 |
| PDZK1IP1 | PDZK1 interacting protein 1 | 0.00595237 |
| COG7 | component of oligomeric golgi complex 7 | 0.00594127 |
| KLK11 | kallikrein-related peptidase 11 | 0.00593223 |
| ATF3 | activating transcription factor 3 | 0.00582811 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.005827 |
| LCN2 | lipocalin 2 | 0.00581975 |
| RNF167 | ring finger protein 167 | 0.00574645 |
| CSRP2 | cysteine and glycine-rich protein 2 | 0.00574106 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.00573884 |
| RCAN1 | regulator of calcineurin 1 | 0.00570412 |
| KRT19 | keratin 19, type I | 0.00566655 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.00566142 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.00564053 |
| PROM1 | prominin 1 | 0.00563843 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 0.00561047 |
| HSPA1A | heat shock 70kDa protein 1A | 0.00559469 |
| ARG1 | arginase 1 | 0.00559449 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | 0.0055921 |
| TARP | TCR gamma alternate reading frame protein | 0.00550929 |
| IL1R2 | interleukin 1 receptor, type II | 0.00542644 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.00536614 |
| MPO | myeloperoxidase | 0.00535098 |
| ACTN1 | actinin, alpha 1 | 0.00531451 |
| BLNK | B-cell linker | 0.00527796 |
| KIAA0226L | KIAA0226-like | 0.0052762 |
| MT1X | metallothionein 1X | 0.00525648 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | 0.00524993 |
| GDF15 | growth differentiation factor 15 | 0.00521302 |
| RHCG | Rh family, C glycoprotein | 0.0051548 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.00514502 |
| KLK10 | kallikrein-related peptidase 10 | 0.00514236 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.00510921 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | 0.00509363 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | 0.00507548 |
| BPGM | 2,3-bisphosphoglycerate mutase | 0.00502268 |
| AMMECR1 | Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 | 0.0049877 |
| VNN1 | vanin 1 | 0.00498244 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.00497631 |
| PLBD1 | phospholipase B domain containing 1 | 0.00497242 |
| OCRL | oculocerebrorenal syndrome of Lowe | 0.00496184 |
| CSTA | cystatin A (stefin A) | 0.00495688 |
| GUCY2C | guanylate cyclase 2C | 0.0049429 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.00493063 |
| MT1F | metallothionein 1F | 0.00493007 |
| KRT15 | keratin 15, type I | 0.00489936 |
| HSPA2 | heat shock 70kDa protein 2 | 0.00489652 |
| PRR13 | proline rich 13 | 0.0048822 |
| FOSL2 | FOS-like antigen 2 | 0.00487906 |
| HGD | homogentisate 1,2-dioxygenase | 0.00487007 |
| UPP1 | uridine phosphorylase 1 | 0.00484986 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.00484705 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.00484331 |
| EGR1 | early growth response 1 | 0.00483449 |
| CLEC11A | C-type lectin domain family 11, member A | 0.00482611 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0048214 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.00481414 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.00479269 |
| TUFT1 | tuftelin 1 | 0.00479136 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.00477568 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | 0.00475415 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.00471452 |
| ASS1 | argininosuccinate synthase 1 | 0.00470793 |
| FOXG1 | forkhead box G1 | 0.00469528 |
| ADM | adrenomedullin | 0.00468856 |
| CDH16 | cadherin 16, KSP-cadherin | 0.00468516 |
| DNAJC7 | DnaJ (Hsp40) homolog, subfamily C, member 7 | 0.00467728 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | 0.00465055 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.00464204 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | 0.0045975 |
| PRAME | preferentially expressed antigen in melanoma | 0.00459421 |
| DENND1B | DENN/MADD domain containing 1B | 0.00459177 |
| HSPB1 | heat shock 27kDa protein 1 | 0.00457428 |
| KLK13 | kallikrein-related peptidase 13 | 0.00456339 |
| TCL1A | T-cell leukemia/lymphoma 1A | 0.00455975 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | 0.00455036 |
| HSD11B2 | hydroxysteroid (11-beta) dehydrogenase 2 | 0.00454805 |
| IER5 | immediate early response 5 | 0.00454753 |
| HMOX1 | heme oxygenase 1 | 0.004529 |
| TPBG | trophoblast glycoprotein | 0.00452451 |
| HTRA1 | HtrA serine peptidase 1 | 0.00452273 |
| HIST1H2BD | histone cluster 1, H2bd | 0.0045147 |
| OGA | O-GlcNAcase | 0.00450792 |
| RRAGD | Ras-related GTP binding D | 0.00449531 |
| MT1G | metallothionein 1G | 0.0044786 |
| MMP9 | matrix metallopeptidase 9 | 0.00445647 |
| CORO1A | coronin, actin binding protein, 1A | 0.00444442 |
| ALDOB | aldolase B, fructose-bisphosphate | 0.00443557 |
| RND3 | Rho family GTPase 3 | 0.00441685 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | 0.00441644 |
| GLDC | glycine dehydrogenase (decarboxylating) | 0.00439701 |
| PENK | proenkephalin | 0.00439026 |
| PDZK1 | PDZ domain containing 1 | 0.00437939 |
| HIST1H2AC | histone cluster 1, H2ac | 0.00437918 |
| KLF6 | Kruppel-like factor 6 | 0.00437842 |
| ZBTB10 | zinc finger and BTB domain containing 10 | 0.00436865 |
| RGS10 | regulator of G-protein signaling 10 | 0.00436354 |
| HOMER1 | homer scaffolding protein 1 | 0.00434279 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | 0.00432802 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | 0.0043256 |
| SLC4A1 | solute carrier family 4 (anion exchanger), member 1 (Diego blood group) | 0.00432025 |
| CLTB | clathrin, light chain B | 0.00430773 |
| IER3 | immediate early response 3 | 0.00430458 |
| MCL1 | myeloid cell leukemia 1 | 0.00429412 |
| ALDH8A1 | aldehyde dehydrogenase 8 family, member A1 | 0.00424416 |
| CHFR | checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase | 0.0042435 |
| PRPF4 | pre-mRNA processing factor 4 | 0.00422945 |
| FOXL2 | forkhead box L2 | 0.00422927 |
| TUBB2B | tubulin, beta 2B class IIb | 0.00422747 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.00420791 |
| TFF3 | trefoil factor 3 (intestinal) | 0.0042005 |
| GPM6B | glycoprotein M6B | 0.00419571 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | 0.00419206 |
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 | 0.00418423 |
| TOX | thymocyte selection-associated high mobility group box | 0.00417672 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.00417556 |
| S100A14 | S100 calcium binding protein A14 | 0.00416883 |
| MICB | MHC class I polypeptide-related sequence B | 0.00416829 |
| MAOB | monoamine oxidase B | 0.00416681 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.00416538 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.00416117 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.004154 |
| GRN | granulin | 0.00415171 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.00415121 |
| TRAF4 | TNF receptor-associated factor 4 | 0.00413886 |
| MMP8 | matrix metallopeptidase 8 | 0.00413827 |
| RPS26 | ribosomal protein S26 | 0.00413585 |
| CRABP2 | cellular retinoic acid binding protein 2 | 0.00413151 |
| CTSD | cathepsin D | 0.00412185 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.00412027 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | 0.00411822 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0040955 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.00409068 |
| CEACAM8 | carcinoembryonic antigen-related cell adhesion molecule 8 | 0.00408837 |
| C1ORF54 | chromosome 1 open reading frame 54 | 0.00408595 |
| NLRP2 | NLR family, pyrin domain containing 2 | 0.0040835 |
| ZNF432 | zinc finger protein 432 | 0.00408254 |
| EZR | ezrin | 0.00408171 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | 0.0040779 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.00407065 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.00406 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.00404802 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | 0.00403605 |
| ITM2C | integral membrane protein 2C | 0.00402798 |
| YPEL5 | yippee-like 5 (Drosophila) | 0.0040158 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.00399249 |
| GPR137B | G protein-coupled receptor 137B | 0.00398564 |
| COTL1 | coactosin-like F-actin binding protein 1 | 0.00398452 |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) | 0.00397853 |
| CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma | 0.00396488 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | 0.00396379 |
| NRCAM | neuronal cell adhesion molecule | 0.00396002 |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 | 0.0039454 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | 0.00392646 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.00390915 |
| ZMAT3 | zinc finger, matrin-type 3 | 0.00390089 |
| IL2RG | interleukin 2 receptor, gamma | 0.00388562 |
| GM2A | GM2 ganglioside activator | 0.00388254 |
| CLDN8 | claudin 8 | 0.0038808 |
| CNN1 | calponin 1, basic, smooth muscle | 0.00387703 |
| TTC39A | tetratricopeptide repeat domain 39A | 0.00387435 |
| SPIB | Spi-B transcription factor (Spi-1/PU.1 related) | 0.00386074 |
| MMP12 | matrix metallopeptidase 12 | 0.00383413 |
| EHD1 | EH-domain containing 1 | 0.00383264 |
| FCGBP | Fc fragment of IgG binding protein | 0.00381288 |
| PEG3 | paternally expressed 3 | 0.0037925 |
| TPM2 | tropomyosin 2 (beta) | 0.00378872 |
| EDN1 | endothelin 1 | 0.00378066 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.00376411 |
| ACOT7 | acyl-CoA thioesterase 7 | 0.00376247 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.00375736 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.00375723 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 0.00375503 |
| ALAS2 | 5'-aminolevulinate synthase 2 | 0.0037547 |
| CYBA | cytochrome b-245, alpha polypeptide | 0.00375327 |
| LBH | limb bud and heart development | 0.00375324 |
| TP53I3 | tumor protein p53 inducible protein 3 | 0.00374961 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.00374797 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.00374732 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | 0.00374683 |
| ZYX | zyxin | 0.00374296 |
| CHP1 | calcineurin-like EF-hand protein 1 | 0.00372625 |
| VAV3 | vav 3 guanine nucleotide exchange factor | 0.00372547 |
| NRIP3 | nuclear receptor interacting protein 3 | 0.0037213 |
| RAB29 | RAB29, member RAS oncogene family | 0.00371423 |
| RBM34 | RNA binding motif protein 34 | 0.00371152 |
| ECM1 | extracellular matrix protein 1 | 0.00370865 |
| MT1HL1 | metallothionein 1H-like 1 | 0.00370792 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.00370553 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.00370171 |
| FGF2 | fibroblast growth factor 2 (basic) | 0.00368648 |
| LCK | LCK proto-oncogene, Src family tyrosine kinase | 0.00368323 |
| CRABP1 | cellular retinoic acid binding protein 1 | 0.00366274 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric | 0.00366121 |
| TFPT | TCF3 (E2A) fusion partner (in childhood Leukemia) | 0.00365251 |
| AP1G1 | adaptor-related protein complex 1, gamma 1 subunit | 0.00362985 |
| IL1RN | interleukin 1 receptor antagonist | 0.00362907 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.00362516 |
| VEGFA | vascular endothelial growth factor A | 0.00362329 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | 0.00362212 |
| EMX2 | empty spiracles homeobox 2 | 0.00361243 |
| ZFYVE9 | zinc finger, FYVE domain containing 9 | 0.00361186 |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) | 0.00360719 |
| DPYS | dihydropyrimidinase | 0.00360532 |
| CROT | carnitine O-octanoyltransferase | 0.00360345 |
| ARMCX6 | armadillo repeat containing, X-linked 6 | 0.00360168 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 | 0.00359192 |
| LITAF | lipopolysaccharide-induced TNF factor | 0.00358692 |
| CREB3L1 | cAMP responsive element binding protein 3-like 1 | 0.0035715 |
| HOXB7 | homeobox B7 | 0.00356823 |
| NUP58 | nucleoporin 58 | 0.0035668 |
| FCN1 | ficolin (collagen/fibrinogen domain containing) 1 | 0.00356487 |
| ABHD4 | abhydrolase domain containing 4 | 0.00355592 |
| NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 | 0.00355458 |
| SLC12A1 | solute carrier family 12 (sodium/potassium/chloride transporter), member 1 | 0.00355261 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.00354929 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | 0.00354747 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.00354443 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.00354273 |
| IGFBP4 | insulin-like growth factor binding protein 4 | 0.0035418 |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase | 0.00354007 |
| QPCT | glutaminyl-peptide cyclotransferase | 0.00353558 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | 0.00352456 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0102607 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.00970324 |
| FABP4 | fatty acid binding protein 4, adipocyte | -0.00897914 |
| PMP22 | peripheral myelin protein 22 | -0.00892486 |
| CFB | complement factor B | -0.00839891 |
| ASPN | asporin | -0.00810945 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.00794255 |
| C3 | complement component 3 | -0.00774409 |
| RGS5 | regulator of G-protein signaling 5 | -0.00754806 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.00715066 |
| S100A2 | S100 calcium binding protein A2 | -0.00692397 |
| COL11A1 | collagen, type XI, alpha 1 | -0.00689375 |
| ANOS1 | anosmin 1 | -0.00655655 |
| AHR | aryl hydrocarbon receptor | -0.0065123 |
| COL10A1 | collagen, type X, alpha 1 | -0.00649975 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.00640823 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.00631524 |
| CD320 | CD320 molecule | -0.0062976 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.00628746 |
| FASN | fatty acid synthase | -0.00623304 |
| CLIC5 | chloride intracellular channel 5 | -0.00619322 |
| LUM | lumican | -0.00618441 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.00617302 |
| ADGRF5 | adhesion G protein-coupled receptor F5 | -0.00610074 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.00609581 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | -0.00609474 |
| CLEC2B | C-type lectin domain family 2, member B | -0.00606894 |
| COMP | cartilage oligomeric matrix protein | -0.00605558 |
| CD93 | CD93 molecule | -0.00605527 |
| PLXNC1 | plexin C1 | -0.006003 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | -0.00597426 |
| ELK3 | ELK3, ETS-domain protein (SRF accessory protein 2) | -0.00596104 |
| LRRC15 | leucine rich repeat containing 15 | -0.00589544 |
| CEL | carboxyl ester lipase | -0.00587819 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase | -0.00586477 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0058645 |
| CFH | complement factor H | -0.00583618 |
| NINJ2 | ninjurin 2 | -0.00577294 |
| SLC29A1 | solute carrier family 29 (equilibrative nucleoside transporter), member 1 | -0.00574836 |
| CD163 | CD163 molecule | -0.00574481 |
| NNMT | nicotinamide N-methyltransferase | -0.00572743 |
| ADIPOQ | adiponectin, C1Q and collagen domain containing | -0.005655 |
| SEPTIN10 | septin 10 | -0.00563817 |
| RIN2 | Ras and Rab interactor 2 | -0.00558222 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | -0.00556997 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.00554606 |
| MAP7 | microtubule-associated protein 7 | -0.00554515 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.00553938 |
| RAPSN | receptor-associated protein of the synapse | -0.00547566 |
| KIF5B | kinesin family member 5B | -0.00545479 |
| BGN | biglycan | -0.00545477 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | -0.00544549 |
| FBN1 | fibrillin 1 | -0.00541839 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 | -0.00541625 |
| FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) | -0.00538435 |
| IFRD2 | interferon-related developmental regulator 2 | -0.00537612 |
| DCN | decorin | -0.00536572 |
| F13A1 | coagulation factor XIII, A1 polypeptide | -0.00536155 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | -0.00535886 |
| FBLN1 | fibulin 1 | -0.00535482 |
| RTN1 | reticulon 1 | -0.00535295 |
| CCDC92 | coiled-coil domain containing 92 | -0.00534808 |
| PRRX1 | paired related homeobox 1 | -0.00531919 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | -0.00528646 |
| PDGFRL | platelet-derived growth factor receptor-like | -0.00526635 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.00526421 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.00525236 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -0.00522771 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.00520382 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | -0.00510835 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.00510317 |
| FZD10 | frizzled class receptor 10 | -0.00508579 |
| MSLN | mesothelin | -0.00507201 |
| RCAN2 | regulator of calcineurin 2 | -0.00506836 |
| CCP110 | centriolar coiled coil protein 110kDa | -0.00504165 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -0.00504073 |
| A2M | alpha-2-macroglobulin | -0.00502048 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.00498929 |
| MPZL2 | myelin protein zero-like 2 | -0.00498477 |
| CDK2AP1 | cyclin-dependent kinase 2 associated protein 1 | -0.00497294 |
| PRDX2 | peroxiredoxin 2 | -0.00496089 |
| DOCK9 | dedicator of cytokinesis 9 | -0.00495636 |
| OPHN1 | oligophrenin 1 | -0.0049417 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.00493488 |
| SCD5 | stearoyl-CoA desaturase 5 | -0.00493132 |
| PLSCR4 | phospholipid scramblase 4 | -0.00492798 |
| SFRP4 | secreted frizzled-related protein 4 | -0.00491545 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.00491249 |
| CBX1 | chromobox homolog 1 | -0.0048721 |
| FRZB | frizzled-related protein | -0.00486511 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 | -0.00486383 |
| FZD6 | frizzled class receptor 6 | -0.00483071 |
| GIMAP6 | GTPase, IMAP family member 6 | -0.00480215 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | -0.0047822 |
| MXRA5 | matrix-remodelling associated 5 | -0.00477839 |
| HAT1 | histone acetyltransferase 1 | -0.00476533 |
| COL15A1 | collagen, type XV, alpha 1 | -0.00475155 |
| MTA1 | metastasis associated 1 | -0.00474636 |
| SOX11 | SRY (sex determining region Y)-box 11 | -0.00471187 |
| ABHD3 | abhydrolase domain containing 3 | -0.0046877 |
| PLXNB1 | plexin B1 | -0.00467284 |
| ADIRF | adipogenesis regulatory factor | -0.00466699 |
| CPB1 | carboxypeptidase B1 (tissue) | -0.00464057 |
| CLU | clusterin | -0.0046376 |
| MGP | matrix Gla protein | -0.00461823 |
| NKTR | natural killer cell triggering receptor | -0.00460189 |
| TCF4 | transcription factor 4 | -0.00457603 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | -0.00455907 |
| TPSAB1 | tryptase alpha/beta 1 | -0.00453638 |
| CTSK | cathepsin K | -0.00451599 |
| GPX2 | glutathione peroxidase 2 | -0.0045138 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A | -0.00450574 |
| TLE2 | transducin-like enhancer of split 2 | -0.00448889 |
| SUB1 | SUB1 homolog (S. cerevisiae) | -0.00445079 |
| TLR4 | toll-like receptor 4 | -0.00440332 |
| CP | ceruloplasmin (ferroxidase) | -0.00438373 |
| PER3 | period circadian clock 3 | -0.0043755 |
| PIP | prolactin-induced protein | -0.00436399 |
| FBLN2 | fibulin 2 | -0.00435558 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.00435271 |
| KIF14 | kinesin family member 14 | -0.00433796 |
| ELN | elastin | -0.0043356 |
| MANSC1 | MANSC domain containing 1 | -0.00433539 |
| DUSP7 | dual specificity phosphatase 7 | -0.00432051 |
| OMD | osteomodulin | -0.00431465 |
| PLIN1 | perilipin 1 | -0.00430549 |
| MN1 | meningioma (disrupted in balanced translocation) 1 | -0.00429306 |
| PCLAF | PCNA clamp associated factor | -0.00429201 |
| TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) | -0.00428538 |
| PRKCD | protein kinase C, delta | -0.00423814 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.00423728 |
| CLGN | calmegin | -0.00423362 |
| IFT81 | intraflagellar transport 81 | -0.00422985 |
| BMI1 | BMI1 proto-oncogene, polycomb ring finger | -0.00422875 |
| TWIST1 | twist family bHLH transcription factor 1 | -0.00422544 |
| TNS2 | tensin 2 | -0.00417437 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0041685 |
| RTN2 | reticulon 2 | -0.00410733 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | -0.00410105 |
| NPY1R | neuropeptide Y receptor Y1 | -0.00407598 |
| MFAP2 | microfibrillar-associated protein 2 | -0.00406879 |
| DHX30 | DEAH (Asp-Glu-Ala-His) box helicase 30 | -0.00406779 |
| CCL8 | chemokine (C-C motif) ligand 8 | -0.00406528 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.00405284 |
| SV2C | synaptic vesicle glycoprotein 2C | -0.00404551 |
| PCDH17 | protocadherin 17 | -0.00404399 |
| SREBF1 | sterol regulatory element binding transcription factor 1 | -0.0040434 |
| COLEC12 | collectin sub-family member 12 | -0.0040425 |
| AQP1 | aquaporin 1 (Colton blood group) | -0.00401768 |
| FCGR2B | Fc fragment of IgG, low affinity IIb, receptor (CD32) | -0.00400507 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | -0.00400007 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.00399944 |
| COL5A1 | collagen, type V, alpha 1 | -0.00398856 |
| LAMA4 | laminin, alpha 4 | -0.00396564 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | -0.00394165 |
| PIGB | phosphatidylinositol glycan anchor biosynthesis, class B | -0.00393932 |
| ASPH | aspartate beta-hydroxylase | -0.00391771 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | -0.00389402 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | -0.00389294 |
| APLNR | apelin receptor | -0.00388961 |
| PAQR4 | progestin and adipoQ receptor family member IV | -0.0038893 |
| ATP9A | ATPase, class II, type 9A | -0.00388805 |
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4A | -0.0038866 |
| CCL21 | chemokine (C-C motif) ligand 21 | -0.00387674 |
| DPM3 | dolichyl-phosphate mannosyltransferase polypeptide 3 | -0.00386341 |
| ACAT1 | acetyl-CoA acetyltransferase 1 | -0.00386259 |
| GAS1 | growth arrest-specific 1 | -0.00385021 |
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide | -0.00384789 |
| PLD3 | phospholipase D family, member 3 | -0.00383572 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | -0.00382584 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0038245 |
| SLCO3A1 | solute carrier organic anion transporter family, member 3A1 | -0.00382333 |
| CTBP1 | C-terminal binding protein 1 | -0.00382196 |
| PPL | periplakin | -0.00381651 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -0.00381217 |
| C1QA | complement component 1, q subcomponent, A chain | -0.00381114 |
| RDX | radixin | -0.00380896 |
| NUMA1 | nuclear mitotic apparatus protein 1 | -0.00380485 |
| CLEC3B | C-type lectin domain family 3, member B | -0.00380273 |
| MGST2 | microsomal glutathione S-transferase 2 | -0.00379297 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.00378802 |
| MFAP4 | microfibrillar-associated protein 4 | -0.00378719 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.00377975 |
| FADS1 | fatty acid desaturase 1 | -0.00377458 |
| RPA3 | replication protein A3, 14kDa | -0.00376868 |
| VWF | von Willebrand factor | -0.0037675 |
| TNS3 | tensin 3 | -0.00376103 |
| ARHGEF40 | Rho guanine nucleotide exchange factor (GEF) 40 | -0.00375593 |
| CD44 | CD44 molecule (Indian blood group) | -0.00374229 |
| XAF1 | XIAP associated factor 1 | -0.00373882 |
| KIF1B | kinesin family member 1B | -0.00372844 |
| CPE | carboxypeptidase E | -0.00372628 |
| NDUFAF3 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 3 | -0.00372216 |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 | -0.00371826 |
| WDR6 | WD repeat domain 6 | -0.00371779 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | -0.00371336 |
| SPARCL1 | SPARC-like 1 (hevin) | -0.00371311 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 | -0.00371028 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | -0.00369149 |
| DHCR7 | 7-dehydrocholesterol reductase | -0.0036914 |
| DAAM2 | dishevelled associated activator of morphogenesis 2 | -0.00368975 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.00368785 |
| IFI44L | interferon-induced protein 44-like | -0.00368535 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | -0.00367834 |
| RGS1 | regulator of G-protein signaling 1 | -0.00367777 |
| NID1 | nidogen 1 | -0.00367436 |
| UCKL1 | uridine-cytidine kinase 1-like 1 | -0.00367269 |
| SLCO2B1 | solute carrier organic anion transporter family, member 2B1 | -0.00366449 |
| DKK2 | dickkopf WNT signaling pathway inhibitor 2 | -0.0036573 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0036553 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.00365516 |
| ADGRG2 | adhesion G protein-coupled receptor G2 | -0.0036522 |
| SNAI2 | snail family zinc finger 2 | -0.00365109 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.00364922 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | -0.00363747 |
| FILIP1L | filamin A interacting protein 1-like | -0.00363418 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.00362982 |
| S100A4 | S100 calcium binding protein A4 | -0.00362726 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.00362055 |
| INSIG1 | insulin induced gene 1 | -0.00361438 |
| JCHAIN | joining chain of multimeric IgA and IgM | -0.00360805 |
| BST2 | bone marrow stromal cell antigen 2 | -0.00360068 |
| NELL2 | NEL-like 2 (chicken) | -0.00359393 |
| CBX3 | chromobox homolog 3 | -0.00359385 |
| PLN | phospholamban | -0.00359165 |
| BRD3 | bromodomain containing 3 | -0.0035839 |
| GLT8D2 | glycosyltransferase 8 domain containing 2 | -0.0035832 |
| COL3A1 | collagen, type III, alpha 1 | -0.00358254 |
| EGFL6 | EGF-like-domain, multiple 6 | -0.00357797 |
| ECM2 | extracellular matrix protein 2, female organ and adipocyte specific | -0.00357558 |
| RET | ret proto-oncogene | -0.00357428 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.00356914 |
| LZTFL1 | leucine zipper transcription factor-like 1 | -0.00356637 |
| CYP2B6 | cytochrome P450, family 2, subfamily B, polypeptide 6 | -0.00356539 |
| OLFML2B | olfactomedin-like 2B | -0.00356516 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | -0.00354575 |
| LRP8 | low density lipoprotein receptor-related protein 8, apolipoprotein e receptor | -0.00354225 |
| MFAP5 | microfibrillar associated protein 5 | -0.00352464 |
| GATA2 | GATA binding protein 2 | -0.00351612 |
| CYBRD1 | cytochrome b reductase 1 | -0.00351392 |
| BICC1 | BicC family RNA binding protein 1 | -0.00350338 |
| KAZN | kazrin, periplakin interacting protein | -0.00350231 |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | -0.00350039 |
| PCMTD2 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 | -0.00349929 |
| MSANTD2 | Myb/SANT-like DNA-binding domain containing 2 | -0.00349907 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.00349385 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | -0.00349122 |
| GOLGA8A | golgin A8 family, member A | -0.00348883 |
| OLFML2A | olfactomedin-like 2A | -0.00348329 |
