PRKCQ Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description protein kinase C, theta|Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipid-dependent protein kinase. This kinase is important for T-cell activation. It is required for the activation of the transcription factors NF-kappaB and AP-1, and may link the T cell receptor (TCR) signaling complex to the activation of the transcription factors. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 5588)
External Link http://www.ncbi.nlm.nih.gov/gene/5588
Similar Terms
Downloads & Tools

Genes

363 interacting proteins for PRKCQ from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
AAK1 AP2 associated kinase 1
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACOX3 acyl-CoA oxidase 3, pristanoyl
ACTB actin, beta
ACTN4 actinin, alpha 4
ACVR1 activin A receptor, type I
ACVR1B activin A receptor, type IB
ACVR2B activin A receptor, type IIB
ADAM17 ADAM metallopeptidase domain 17
ADAM28 ADAM metallopeptidase domain 28
ADCK1 aarF domain containing kinase 1
ADCK3 aarF domain containing kinase 3
ADK adenosine kinase
AFF4 AF4/FMR2 family, member 4
AHRR aryl-hydrocarbon receptor repressor
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALDOA aldolase A, fructose-bisphosphate
ALPK3 alpha-kinase 3
ANAPC5 anaphase promoting complex subunit 5
ANAPC7 anaphase promoting complex subunit 7
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
ANXA2 annexin A2
AP2A1 adaptor-related protein complex 2, alpha 1 subunit
AP2B1 adaptor-related protein complex 2, beta 1 subunit
AP2M1 adaptor-related protein complex 2, mu 1 subunit
ARAF A-Raf proto-oncogene, serine/threonine kinase
ATAD3B ATPase family, AAA domain containing 3B
ATF2 activating transcription factor 2
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1
AURKA aurora kinase A
AURKB aurora kinase B
AZI2 5-azacytidine induced 2
B2M beta-2-microglobulin
BAD BCL2-associated agonist of cell death
BCAR1 breast cancer anti-estrogen resistance 1
BCL10 B-cell CLL/lymphoma 10
BMP2K BMP2 inducible kinase
BMPR1A bone morphogenetic protein receptor, type IA
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRD3 bromodomain containing 3
BRD4 bromodomain containing 4
BTK Bruton agammaglobulinemia tyrosine kinase
C2CD5 C2 calcium-dependent domain containing 5
CABIN1 calcineurin binding protein 1
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit
CACNA1E calcium channel, voltage-dependent, R type, alpha 1E subunit
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CACNB2 calcium channel, voltage-dependent, beta 2 subunit
CACNB3 calcium channel, voltage-dependent, beta 3 subunit
CACNB4 calcium channel, voltage-dependent, beta 4 subunit
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CAMK2D calcium/calmodulin-dependent protein kinase II delta
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CARD11 caspase recruitment domain family, member 11
CASP3 caspase 3, apoptosis-related cysteine peptidase
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CCNH cyclin H
CD247 CD247 molecule
CD28 CD28 molecule
CD3D CD3d molecule, delta (CD3-TCR complex)
CD3E CD3e molecule, epsilon (CD3-TCR complex)
CD3G CD3g molecule, gamma (CD3-TCR complex)
CD4 CD4 molecule
CD80 CD80 molecule
CD86 CD86 molecule
CD8A CD8a molecule
CD8B CD8b molecule
CDK1 cyclin-dependent kinase 1
CDK12 cyclin-dependent kinase 12
CDK2 cyclin-dependent kinase 2
CDK5 cyclin-dependent kinase 5
CDK7 cyclin-dependent kinase 7
CDK9 cyclin-dependent kinase 9
CHRM1 cholinergic receptor, muscarinic 1
CHRM2 cholinergic receptor, muscarinic 2
CHRM3 cholinergic receptor, muscarinic 3
CHRM4 cholinergic receptor, muscarinic 4
CHRM5 cholinergic receptor, muscarinic 5
CHUK conserved helix-loop-helix ubiquitous kinase
CISH cytokine inducible SH2-containing protein
CLK1 CDC-like kinase 1
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CSK c-src tyrosine kinase
CSNK1A1 casein kinase 1, alpha 1
CSNK1D casein kinase 1, delta
CSNK1E casein kinase 1, epsilon
CSNK1G3 casein kinase 1, gamma 3
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CSNK2A2 casein kinase 2, alpha prime polypeptide
CSNK2B casein kinase 2, beta polypeptide
DAB2IP DAB2 interacting protein
DCK deoxycytidine kinase
DCTPP1 dCTP pyrophosphatase 1
DDR1 discoidin domain receptor tyrosine kinase 1
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DOK2 docking protein 2, 56kDa
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
EGFR epidermal growth factor receptor
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4
EIF3J eukaryotic translation initiation factor 3, subunit J
EPHB1 EPH receptor B1
EPHB2 EPH receptor B2
EPHB4 EPH receptor B4
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ERBB4 erb-b2 receptor tyrosine kinase 4
EZR ezrin
FER fer (fps/fes related) tyrosine kinase
FGFR1 fibroblast growth factor receptor 1
FGFR2 fibroblast growth factor receptor 2
FGFR3 fibroblast growth factor receptor 3
FGFR4 fibroblast growth factor receptor 4
FKBP1A FK506 binding protein 1A, 12kDa
FRS2 fibroblast growth factor receptor substrate 2
FRYL FRY-like
FYB FYN binding protein
FYN FYN proto-oncogene, Src family tyrosine kinase
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GAB1 GRB2-associated binding protein 1
GAB2 GRB2-associated binding protein 2
GAB3 GRB2-associated binding protein 3
GAK cyclin G associated kinase
GAPVD1 GTPase activating protein and VPS9 domains 1
GFPT1 glutamine--fructose-6-phosphate transaminase 1
GLRX3 glutaredoxin 3
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GNB5 guanine nucleotide binding protein (G protein), beta 5
GRAMD1A GRAM domain containing 1A
GRAP GRB2-related adaptor protein
GRAP2 GRB2-related adaptor protein 2
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C
GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2D
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A
GRM5 glutamate receptor, metabotropic 5
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
HABP4 hyaluronan binding protein 4
HCK HCK proto-oncogene, Src family tyrosine kinase
HIPK1 homeodomain interacting protein kinase 1
HIST1H3B histone cluster 1, H3b
HLA-A major histocompatibility complex, class I, A
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2
HLA-DRA major histocompatibility complex, class II, DR alpha
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-DRB3 major histocompatibility complex, class II, DR beta 3
HLA-DRB4 major histocompatibility complex, class II, DR beta 4
HLA-DRB5 major histocompatibility complex, class II, DR beta 5
HRAS Harvey rat sarcoma viral oncogene homolog
HRNR hornerin
HSF1 heat shock transcription factor 1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
ICAM3 intercellular adhesion molecule 3
IGF1 insulin-like growth factor 1 (somatomedin C)
IGHE immunoglobulin heavy constant epsilon
IGKC immunoglobulin kappa constant
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV4-1 immunoglobulin kappa variable 4-1
IGLC1 immunoglobulin lambda constant 1 (Mcg marker)
IGLC2 immunoglobulin lambda constant 2 (Kern-Oz- marker)
IGLC3 immunoglobulin lambda constant 3 (Kern-Oz+ marker)
IGLC6 immunoglobulin lambda constant 6 (Kern+Oz- marker, gene/pseudogene)
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
INPPL1 inositol polyphosphate phosphatase-like 1
IRS1 insulin receptor substrate 1
JAK1 Janus kinase 1
JAK2 Janus kinase 2
JUND jun D proto-oncogene
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KIAA0195 KIAA0195
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KRAS Kirsten rat sarcoma viral oncogene homolog
LAT linker for activation of T cells
LCK LCK proto-oncogene, Src family tyrosine kinase
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
LIMK1 LIM domain kinase 1
LIMK2 LIM domain kinase 2
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae)
LYN LYN proto-oncogene, Src family tyrosine kinase
MALT1 MALT1 paracaspase
MAP2K2 mitogen-activated protein kinase kinase 2
MAP3K11 mitogen-activated protein kinase kinase kinase 11
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MAP3K4 mitogen-activated protein kinase kinase kinase 4
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK6 mitogen-activated protein kinase 6
MAPK8 mitogen-activated protein kinase 8
MAPK9 mitogen-activated protein kinase 9
MARK2 MAP/microtubule affinity-regulating kinase 2
MARK3 MAP/microtubule affinity-regulating kinase 3
MARK4 MAP/microtubule affinity-regulating kinase 4
MEF2A myocyte enhancer factor 2A
MELK maternal embryonic leucine zipper kinase
MLLT1 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1
MNAT1 MNAT CDK-activating kinase assembly factor 1
MSN moesin
MTOR mechanistic target of rapamycin (serine/threonine kinase)
NCK2 NCK adaptor protein 2
NEK11 NIMA-related kinase 11
NEK9 NIMA-related kinase 9
NF1 neurofibromin 1
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NLK nemo-like kinase
NOS3 nitric oxide synthase 3 (endothelial cell)
NQO2 NAD(P)H dehydrogenase, quinone 2
NR2F6 nuclear receptor subfamily 2, group F, member 6
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PDE4A phosphodiesterase 4A, cAMP-specific
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1
PDPK1 3-phosphoinositide dependent protein kinase 1
PEBP1 phosphatidylethanolamine binding protein 1
PEBP4 phosphatidylethanolamine-binding protein 4
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
PKM pyruvate kinase, muscle
PKMYT1 protein kinase, membrane associated tyrosine/threonine 1
PKN1 protein kinase N1
PKN3 protein kinase N3
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLCG1 phospholipase C, gamma 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLD1 phospholipase D1, phosphatidylcholine-specific
PLD2 phospholipase D2
PLK4 polo-like kinase 4
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PRKCA protein kinase C, alpha
PRKCB protein kinase C, beta
PRKCD protein kinase C, delta
PRKCG protein kinase C, gamma
PRKCZ protein kinase C, zeta
PRKD2 protein kinase D2
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PTK2 protein tyrosine kinase 2
PTK2B protein tyrosine kinase 2 beta
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTPN7 protein tyrosine phosphatase, non-receptor type 7
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RASA1 RAS p21 protein activator (GTPase activating protein) 1
RASA2 RAS p21 protein activator 2
RASA4 RAS p21 protein activator 4
RASA4B RAS p21 protein activator 4B
RASAL2 RAS protein activator like 2
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated)
RDX radixin
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RGS9 regulator of G-protein signaling 9
RGS9BP regulator of G protein signaling 9 binding protein
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RIPK2 receptor-interacting serine-threonine kinase 2
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
SACK1A scaffolding CK1 anchoring protein A
SDC4 syndecan 4
SEC16A SEC16 homolog A (S. cerevisiae)
SELL selectin L
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SHC2 SHC (Src homology 2 domain containing) transforming protein 2
SHC3 SHC (Src homology 2 domain containing) transforming protein 3
SIK2 salt-inducible kinase 2
SIK3 SIK family kinase 3
SLK STE20-like kinase
SOS1 son of sevenless homolog 1 (Drosophila)
SOS2 son of sevenless homolog 2 (Drosophila)
SPEG SPEG complex locus
SPHK1 sphingosine kinase 1
SPHK2 sphingosine kinase 2
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRRM2 serine/arginine repetitive matrix 2
SSB Sjogren syndrome antigen B (autoantigen La)
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT2 signal transducer and activator of transcription 2, 113kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT4 signal transducer and activator of transcription 4
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
STK16 serine/threonine kinase 16
STK39 serine threonine kinase 39
SYK spleen tyrosine kinase
TAL1 T-cell acute lymphocytic leukemia 1
TANK TRAF family member-associated NFKB activator
TAOK1 TAO kinase 1
TAOK3 TAO kinase 3
TBK1 TANK-binding kinase 1
TBKBP1 TBK1 binding protein 1
TBXA2R thromboxane A2 receptor
TEC tec protein tyrosine kinase
TESK2 testis-specific kinase 2
TGFBR1 transforming growth factor, beta receptor 1
TMX1 thioredoxin-related transmembrane protein 1
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TNIK TRAF2 and NCK interacting kinase
TNK1 tyrosine kinase, non-receptor, 1
TNK2 tyrosine kinase, non-receptor, 2
TP53 tumor protein p53
TRA T cell receptor alpha locus
TRAC T cell receptor alpha constant
TRADD TNFRSF1A-associated via death domain
TRAF2 TNF receptor-associated factor 2
TRB T cell receptor beta locus
TRBC1 T cell receptor beta constant 1
TRBV12-3 T cell receptor beta variable 12-3
TTN titin
TUBA1B tubulin, alpha 1b
TYK2 tyrosine kinase 2
UBC ubiquitin C
UBE2N ubiquitin-conjugating enzyme E2N
UBE2V1 ubiquitin-conjugating enzyme E2 variant 1
ULK3 unc-51 like kinase 3
VAV1 vav 1 guanine nucleotide exchange factor
WEE1 WEE1 G2 checkpoint kinase
WIPF1 WAS/WASL interacting protein family, member 1
YES1 YES proto-oncogene 1, Src family tyrosine kinase
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa