PRKCQ Gene Set

Dataset PhosphoSitePlus Substrates of Kinases
Category physical interactions
Type kinase
Description protein kinase C, theta|Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipid-dependent protein kinase. This kinase is important for T-cell activation. It is required for the activation of the transcription factors NF-kappaB and AP-1, and may link the T cell receptor (TCR) signaling complex to the activation of the transcription factors. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 5588)
External Link http://www.ncbi.nlm.nih.gov/gene/5588
Similar Terms
Downloads & Tools

Genes

30 substrates of the kinase PRKCQ from the curated PhosphoSitePlus Substrates of Kinases dataset.

Symbol Name
AICDA activation-induced cytidine deaminase
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
BAD BCL2-associated agonist of cell death
CARD11 caspase recruitment domain family, member 11
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CCDC88A coiled-coil domain containing 88A
CD4 CD4 molecule
EZR ezrin
FOSL1 FOS-like antigen 1
HABP4 hyaluronan binding protein 4
HIST1H3A histone cluster 1, H3a
ICAM3 intercellular adhesion molecule 3
IRS1 insulin receptor substrate 1
KRAS Kirsten rat sarcoma viral oncogene homolog
MSN moesin
NDRG2 NDRG family member 2
NR2F6 nuclear receptor subfamily 2, group F, member 6
PDPK1 3-phosphoinositide dependent protein kinase 1
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PRKCQ protein kinase C, theta
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTPN7 protein tyrosine phosphatase, non-receptor type 7
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated)
RDX radixin
SPN sialophorin
STK39 serine threonine kinase 39
WIPF1 WAS/WASL interacting protein family, member 1