| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | protein kinase C, zeta|Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 5590) |
| External Link | https://ncbi.nlm.nih.gov/gene/5590 |
| Similar Terms | |
| Downloads & Tools |
497 genes differentially expressed following the PRKCZ gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LTF | lactotransferrin | 0.0144398 |
| METTL7A | methyltransferase like 7A | 0.0137312 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | 0.0130347 |
| DLK1 | delta-like 1 homolog (Drosophila) | 0.0127803 |
| XIC | X chromosome inactivation center | 0.0126936 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.0122945 |
| FZD6 | frizzled class receptor 6 | 0.0120798 |
| MAP7 | microtubule-associated protein 7 | 0.0117266 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | 0.0113214 |
| COL4A5 | collagen, type IV, alpha 5 | 0.0110231 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0108769 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0102156 |
| CD9 | CD9 molecule | 0.0101815 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.0100982 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.0100885 |
| FGFR2 | fibroblast growth factor receptor 2 | 0.00988568 |
| SLC31A2 | solute carrier family 31 (copper transporter), member 2 | 0.00975333 |
| S100P | S100 calcium binding protein P | 0.00969461 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.00952703 |
| WFDC2 | WAP four-disulfide core domain 2 | 0.0095233 |
| CCP110 | centriolar coiled coil protein 110kDa | 0.00945075 |
| HCRT | hypocretin (orexin) neuropeptide precursor | 0.00920183 |
| NCK1 | NCK adaptor protein 1 | 0.00919741 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 | 0.00900569 |
| SLC15A2 | solute carrier family 15 (oligopeptide transporter), member 2 | 0.00900399 |
| S100A12 | S100 calcium binding protein A12 | 0.00898107 |
| DEFA4 | defensin, alpha 4, corticostatin | 0.00897184 |
| RAD51AP1 | RAD51 associated protein 1 | 0.00894007 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.00886308 |
| MPZL2 | myelin protein zero-like 2 | 0.00884206 |
| CCDC176 | coiled-coil domain containing 176 | 0.00857389 |
| SDC2 | syndecan 2 | 0.00855378 |
| KYNU | kynureninase | 0.00852772 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | 0.00842963 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B | 0.0084212 |
| MT1F | metallothionein 1F | 0.00841232 |
| CDS1 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 | 0.00838071 |
| KRT5 | keratin 5, type II | 0.00838005 |
| COL15A1 | collagen, type XV, alpha 1 | 0.00837238 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.00832956 |
| UPK1B | uroplakin 1B | 0.00830109 |
| SYT1 | synaptotagmin I | 0.008245 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | 0.00817454 |
| MECOM | MDS1 and EVI1 complex locus | 0.00816723 |
| CAMP | cathelicidin antimicrobial peptide | 0.00816235 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.00812543 |
| PTK2 | protein tyrosine kinase 2 | 0.00806861 |
| PRPF4 | pre-mRNA processing factor 4 | 0.00805999 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | 0.00801714 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 0.00796435 |
| RFC5 | replication factor C (activator 1) 5, 36.5kDa | 0.00793784 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.00786973 |
| ANXA1 | annexin A1 | 0.00783198 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | 0.00778291 |
| LPAR1 | lysophosphatidic acid receptor 1 | 0.00773924 |
| EHF | ets homologous factor | 0.00771969 |
| MGLL | monoglyceride lipase | 0.0076385 |
| BPI | bactericidal/permeability-increasing protein | 0.00762457 |
| CLCA4 | chloride channel accessory 4 | 0.00760276 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.00759157 |
| GRAMD1C | GRAM domain containing 1C | 0.00758688 |
| ANXA3 | annexin A3 | 0.00757709 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | 0.00745503 |
| SFRP1 | secreted frizzled-related protein 1 | 0.00744463 |
| CHN1 | chimerin 1 | 0.0074335 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.00731227 |
| CD58 | CD58 molecule | 0.00730389 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.00723618 |
| VAMP7 | vesicle-associated membrane protein 7 | 0.00723393 |
| KRT23 | keratin 23, type I | 0.00723236 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | 0.00722955 |
| EFHC2 | EF-hand domain (C-terminal) containing 2 | 0.00722602 |
| SUB1 | SUB1 homolog (S. cerevisiae) | 0.00721152 |
| GRB7 | growth factor receptor-bound protein 7 | 0.00720541 |
| CEACAM8 | carcinoembryonic antigen-related cell adhesion molecule 8 | 0.00717727 |
| SRGN | serglycin | 0.00717422 |
| MSH2 | mutS homolog 2 | 0.00716383 |
| NIBAN1 | niban apoptosis regulator 1 | 0.00712824 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.00708741 |
| EPCAM | epithelial cell adhesion molecule | 0.00705247 |
| DYNLT1 | dynein, light chain, Tctex-type 1 | 0.00704863 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.00704844 |
| LPAR6 | lysophosphatidic acid receptor 6 | 0.00704603 |
| PALM | paralemmin | 0.00702449 |
| PROM1 | prominin 1 | 0.00701809 |
| ASF1A | anti-silencing function 1A histone chaperone | 0.00701661 |
| PBK | PDZ binding kinase | 0.00701366 |
| PPM1H | protein phosphatase, Mg2+/Mn2+ dependent, 1H | 0.00700893 |
| ITGA6 | integrin, alpha 6 | 0.00700737 |
| CCNC | cyclin C | 0.00697546 |
| FKBP4 | FK506 binding protein 4, 59kDa | 0.00692351 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 0.0068913 |
| PLS1 | plastin 1 | 0.00688371 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.00687552 |
| ARMT1 | acidic residue methyltransferase 1 | 0.00684844 |
| PIR | pirin (iron-binding nuclear protein) | 0.00683911 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.00683589 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.00682483 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | 0.00680797 |
| PLP2 | proteolipid protein 2 (colonic epithelium-enriched) | 0.00678321 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 | 0.00677884 |
| HIST1H2AC | histone cluster 1, H2ac | 0.00674751 |
| JCHAIN | joining chain of multimeric IgA and IgM | 0.00673947 |
| MMP10 | matrix metallopeptidase 10 | 0.00671633 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | 0.00667903 |
| TSPAN6 | tetraspanin 6 | 0.00667827 |
| PDLIM4 | PDZ and LIM domain 4 | 0.00666766 |
| MDFIC | MyoD family inhibitor domain containing | 0.00666633 |
| SMC1A | structural maintenance of chromosomes 1A | 0.00665979 |
| OGFRL1 | opioid growth factor receptor-like 1 | 0.00662119 |
| SLC38A2 | solute carrier family 38, member 2 | 0.00661181 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | 0.00660854 |
| TXNDC9 | thioredoxin domain containing 9 | 0.00659675 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | 0.00659304 |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 | 0.00659044 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | 0.00658553 |
| CAV2 | caveolin 2 | 0.00655071 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.00654102 |
| IQCK | IQ motif containing K | 0.00654009 |
| BID | BH3 interacting domain death agonist | 0.00653904 |
| WBP5 | WW domain binding protein 5 | 0.00652071 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | 0.0064854 |
| TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) | 0.00647647 |
| CPM | carboxypeptidase M | 0.00646966 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.00645743 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | 0.00645164 |
| PLEKHF2 | pleckstrin homology domain containing, family F (with FYVE domain) member 2 | 0.00641316 |
| FGFR3 | fibroblast growth factor receptor 3 | 0.00640166 |
| MRPL13 | mitochondrial ribosomal protein L13 | 0.00637682 |
| MMP9 | matrix metallopeptidase 9 | 0.00637413 |
| EPB41L4B | erythrocyte membrane protein band 4.1 like 4B | 0.00636784 |
| C4ORF19 | chromosome 4 open reading frame 19 | 0.00636746 |
| MAGEA3 | melanoma antigen family A3 | 0.00636332 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | 0.00635971 |
| ETNK1 | ethanolamine kinase 1 | 0.00631172 |
| SH3BGRL | SH3 domain binding glutamate-rich protein like | 0.00630449 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | 0.00630298 |
| MDM1 | Mdm1 nuclear protein homolog (mouse) | 0.00629499 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.00629374 |
| CRIP2 | cysteine-rich protein 2 | 0.00628939 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | 0.00627552 |
| NPL | N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) | 0.00627265 |
| KIF20A | kinesin family member 20A | 0.00626061 |
| PSMD5 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 | 0.00624805 |
| RIDA | reactive intermediate imine deaminase A homolog | 0.00623619 |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | 0.00622847 |
| MT1G | metallothionein 1G | 0.006193 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.00618873 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.00616232 |
| IFT57 | intraflagellar transport 57 | 0.00615176 |
| MED21 | mediator complex subunit 21 | 0.00611645 |
| STXBP6 | syntaxin binding protein 6 (amisyn) | 0.00611385 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | 0.00611073 |
| MICB | MHC class I polypeptide-related sequence B | 0.00610169 |
| GDE1 | glycerophosphodiester phosphodiesterase 1 | 0.00605493 |
| HIST1H2AE | histone cluster 1, H2ae | 0.00602454 |
| ABHD3 | abhydrolase domain containing 3 | 0.00601931 |
| PLPP3 | phospholipid phosphatase 3 | 0.00600437 |
| FAM13A | family with sequence similarity 13, member A | 0.0059616 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 | 0.00595389 |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 | 0.00593441 |
| TSC22D1 | TSC22 domain family, member 1 | 0.00591979 |
| SCARB2 | scavenger receptor class B, member 2 | 0.00591507 |
| TMPRSS4 | transmembrane protease, serine 4 | 0.00591102 |
| IL15 | interleukin 15 | 0.00589767 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | 0.00589382 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.00588757 |
| COMT | catechol-O-methyltransferase | 0.00587809 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | 0.00587688 |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 | 0.00587545 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | 0.00585656 |
| ASPH | aspartate beta-hydroxylase | 0.00581831 |
| CLMN | calmin (calponin-like, transmembrane) | 0.00581033 |
| ECT2 | epithelial cell transforming 2 | 0.00580924 |
| ATG5 | autophagy related 5 | 0.00580496 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | 0.00579718 |
| CYB5R4 | cytochrome b5 reductase 4 | 0.00579015 |
| ERI2 | ERI1 exoribonuclease family member 2 | 0.00578384 |
| MTA1 | metastasis associated 1 | 0.00576255 |
| KRT15 | keratin 15, type I | 0.00575368 |
| IQCG | IQ motif containing G | 0.00573013 |
| MMP7 | matrix metallopeptidase 7 | 0.00569985 |
| TXN | thioredoxin | 0.00568982 |
| CLDN1 | claudin 1 | 0.00567877 |
| SEC62 | SEC62 homolog (S. cerevisiae) | 0.00567803 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | 0.00567784 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.00567286 |
| EDRF1 | erythroid differentiation regulatory factor 1 | 0.00565896 |
| PTPN3 | protein tyrosine phosphatase, non-receptor type 3 | 0.00564319 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.00564044 |
| DOCK9 | dedicator of cytokinesis 9 | 0.00563516 |
| CADPS2 | Ca++-dependent secretion activator 2 | 0.00562846 |
| COPS7A | COP9 signalosome subunit 7A | 0.00561956 |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) | 0.00560553 |
| SSX2IP | synovial sarcoma, X breakpoint 2 interacting protein | 0.00559709 |
| DAXX | death-domain associated protein | 0.00559409 |
| LYZ | lysozyme | 0.00558703 |
| DEPTOR | DEP domain containing MTOR-interacting protein | 0.00558304 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 0.00556781 |
| RPAP3 | RNA polymerase II associated protein 3 | 0.00555462 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | 0.00555226 |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 | 0.00555024 |
| HIC2 | hypermethylated in cancer 2 | 0.00552884 |
| FRAT2 | frequently rearranged in advanced T-cell lymphomas 2 | 0.00550972 |
| ITM2C | integral membrane protein 2C | 0.00550564 |
| CETN2 | centrin, EF-hand protein, 2 | 0.00549585 |
| ACADM | acyl-CoA dehydrogenase, C-4 to C-12 straight chain | 0.0054862 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.00547848 |
| AMMECR1 | Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 | 0.00547386 |
| CEP43 | centrosomal protein 43 | 0.00546307 |
| CD34 | CD34 molecule | 0.00546091 |
| HIST1H2BD | histone cluster 1, H2bd | 0.00544116 |
| PGD | phosphogluconate dehydrogenase | 0.00544005 |
| CLDN10 | claudin 10 | 0.00541622 |
| RAD54B | RAD54 homolog B (S. cerevisiae) | 0.00541187 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | 0.00541116 |
| PDZD8 | PDZ domain containing 8 | 0.00540499 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.00539377 |
| ORC3 | origin recognition complex, subunit 3 | 0.00538342 |
| G6PD | glucose-6-phosphate dehydrogenase | 0.00537605 |
| RAB21 | RAB21, member RAS oncogene family | 0.00537386 |
| TSPYL5 | TSPY-like 5 | 0.00537285 |
| ADAMDEC1 | ADAM-like, decysin 1 | 0.00537177 |
| SNX13 | sorting nexin 13 | 0.00534846 |
| TPBG | trophoblast glycoprotein | 0.00534717 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.00534609 |
| E2F8 | E2F transcription factor 8 | 0.00534542 |
| HSPA4L | heat shock 70kDa protein 4-like | 0.0053369 |
| ERGIC2 | ERGIC and golgi 2 | 0.00531808 |
| PHACTR2 | phosphatase and actin regulator 2 | 0.00530898 |
| HLA-DMB | major histocompatibility complex, class II, DM beta | 0.0053084 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | 0.00530838 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.00530482 |
| BDNF | brain-derived neurotrophic factor | 0.00530278 |
| SAP30 | Sin3A-associated protein, 30kDa | 0.00527203 |
| DUSP5 | dual specificity phosphatase 5 | 0.00526771 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | 0.00526237 |
| UPF3B | UPF3 regulator of nonsense transcripts homolog B (yeast) | 0.00525202 |
| CCNO | cyclin O | 0.00524613 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | 0.00522633 |
| PHF3 | PHD finger protein 3 | 0.00521889 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | 0.00521061 |
| PDE8A | phosphodiesterase 8A | 0.00521025 |
| MERTK | MER proto-oncogene, tyrosine kinase | 0.00520317 |
| PRAME | preferentially expressed antigen in melanoma | 0.00517788 |
| TSPAN13 | tetraspanin 13 | 0.00517568 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.00517075 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0273723 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.0209853 |
| PCNA | proliferating cell nuclear antigen | -0.0201435 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.0172787 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -0.0135224 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 | -0.0129671 |
| AEBP1 | AE binding protein 1 | -0.0117631 |
| PNMA2 | paraneoplastic Ma antigen 2 | -0.0112082 |
| SPEN | spen family transcriptional repressor | -0.0110372 |
| CRYAB | crystallin, alpha B | -0.0109613 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | -0.0107804 |
| DCT | dopachrome tautomerase | -0.0107188 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | -0.0100886 |
| THBS2 | thrombospondin 2 | -0.00993877 |
| E2F2 | E2F transcription factor 2 | -0.00981825 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.00973462 |
| TYRP1 | tyrosinase-related protein 1 | -0.00941997 |
| GUSBP3 | glucuronidase, beta pseudogene 3 | -0.00940395 |
| COCH | cochlin | -0.00915387 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | -0.00908771 |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 | -0.00894782 |
| ZNF160 | zinc finger protein 160 | -0.00881139 |
| MXRA5 | matrix-remodelling associated 5 | -0.00870816 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | -0.00867032 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -0.00860128 |
| HOPX | HOP homeobox | -0.00849379 |
| TYMS | thymidylate synthetase | -0.00825434 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | -0.00824964 |
| S100A10 | S100 calcium binding protein A10 | -0.00816855 |
| ZNF721 | zinc finger protein 721 | -0.00801223 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog | -0.00801198 |
| NOP56 | NOP56 ribonucleoprotein | -0.00796861 |
| SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) | -0.007964 |
| NDRG1 | N-myc downstream regulated 1 | -0.00788767 |
| ACAA2 | acetyl-CoA acyltransferase 2 | -0.00784495 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.00783743 |
| MFSD10 | major facilitator superfamily domain containing 10 | -0.00779485 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | -0.00778431 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.00764431 |
| PRKCA | protein kinase C, alpha | -0.00753843 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 | -0.0075219 |
| PRR11 | proline rich 11 | -0.00735828 |
| COLEC12 | collectin sub-family member 12 | -0.00732978 |
| GPR137B | G protein-coupled receptor 137B | -0.0073069 |
| NSG1 | neuron specific gene family member 1 | -0.00718825 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -0.00712064 |
| INAVA | innate immunity activator | -0.0070508 |
| MGP | matrix Gla protein | -0.00698426 |
| HAUS2 | HAUS augmin-like complex, subunit 2 | -0.00697655 |
| INSM1 | insulinoma-associated 1 | -0.00689688 |
| TUBB2B | tubulin, beta 2B class IIb | -0.00688043 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta | -0.00686383 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.00686209 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.00686048 |
| DACH1 | dachshund family transcription factor 1 | -0.00683587 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.00681562 |
| CD1E | CD1e molecule | -0.00680215 |
| PLAAT3 | phospholipase A and acyltransferase 3 | -0.00679654 |
| DPP4 | dipeptidyl-peptidase 4 | -0.00676405 |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) | -0.00673471 |
| FABP7 | fatty acid binding protein 7, brain | -0.00673347 |
| PMEL | premelanosome protein | -0.00672319 |
| ASS1 | argininosuccinate synthase 1 | -0.0067004 |
| DMAC2L | distal membrane arm assembly component 2 like | -0.00660673 |
| F2R | coagulation factor II (thrombin) receptor | -0.0065881 |
| CHGB | chromogranin B | -0.00657238 |
| CYB5A | cytochrome b5 type A (microsomal) | -0.00656131 |
| IER5 | immediate early response 5 | -0.00655631 |
| AAMDC | adipogenesis associated, Mth938 domain containing | -0.00654481 |
| RHOBTB1 | Rho-related BTB domain containing 1 | -0.00653576 |
| LIF | leukemia inhibitory factor | -0.00653161 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.00646101 |
| ZMAT3 | zinc finger, matrin-type 3 | -0.0064429 |
| CPB1 | carboxypeptidase B1 (tissue) | -0.00640359 |
| ATP1A2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide | -0.00639447 |
| TFF2 | trefoil factor 2 | -0.00636889 |
| DSTN | destrin (actin depolymerizing factor) | -0.00636789 |
| CCNB1IP1 | cyclin B1 interacting protein 1, E3 ubiquitin protein ligase | -0.00635876 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 | -0.00634365 |
| ZNF611 | zinc finger protein 611 | -0.00630063 |
| CCND2 | cyclin D2 | -0.00629976 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.00628783 |
| SCAF4 | SR-related CTD-associated factor 4 | -0.00627826 |
| COX7A1 | cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) | -0.00627402 |
| LRRC15 | leucine rich repeat containing 15 | -0.00626393 |
| EDNRB | endothelin receptor type B | -0.00626149 |
| FBXW12 | F-box and WD repeat domain containing 12 | -0.00623558 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.00620282 |
| POLR1B | polymerase (RNA) I polypeptide B, 128kDa | -0.00619644 |
| NRCAM | neuronal cell adhesion molecule | -0.0061899 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.00618446 |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa | -0.00617066 |
| GTF2H2B | general transcription factor IIH, polypeptide 2B (pseudogene) | -0.006146 |
| DSP | desmoplakin | -0.00614562 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | -0.00614504 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -0.0061405 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | -0.00612833 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | -0.00612275 |
| GPX3 | glutathione peroxidase 3 | -0.00609556 |
| CDK5RAP3 | CDK5 regulatory subunit associated protein 3 | -0.00609088 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | -0.0060895 |
| ZNF91 | zinc finger protein 91 | -0.00607757 |
| HSPA1A | heat shock 70kDa protein 1A | -0.00607006 |
| CCDC88A | coiled-coil domain containing 88A | -0.00605677 |
| ARSL | arylsulfatase L | -0.00605007 |
| TTTY15 | testis-specific transcript, Y-linked 15 (non-protein coding) | -0.00598959 |
| CAPN3 | calpain 3, (p94) | -0.00598678 |
| PDZK1IP1 | PDZK1 interacting protein 1 | -0.00596618 |
| LIPG | lipase, endothelial | -0.00594451 |
| ETFB | electron-transfer-flavoprotein, beta polypeptide | -0.0058966 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.00588395 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | -0.00588031 |
| LY6D | lymphocyte antigen 6 complex, locus D | -0.00587736 |
| AGTR1 | angiotensin II receptor, type 1 | -0.00582113 |
| CD1B | CD1b molecule | -0.00581875 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0058129 |
| PMP2 | peripheral myelin protein 2 | -0.00577917 |
| SCD5 | stearoyl-CoA desaturase 5 | -0.0057566 |
| SRSF5 | serine/arginine-rich splicing factor 5 | -0.00573802 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | -0.00572655 |
| KLK5 | kallikrein-related peptidase 5 | -0.00571083 |
| CHD7 | chromodomain helicase DNA binding protein 7 | -0.00569218 |
| SYT11 | synaptotagmin XI | -0.00569167 |
| SETBP1 | SET binding protein 1 | -0.00567828 |
| MEF2C | myocyte enhancer factor 2C | -0.00567759 |
| KIAA0125 | KIAA0125 | -0.00567319 |
| POLR2J4 | polymerase (RNA) II (DNA directed) polypeptide J4, pseudogene | -0.00566679 |
| ZBED2 | zinc finger, BED-type containing 2 | -0.00566242 |
| GOLGA8H | golgin A8 family, member H | -0.00564246 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase | -0.00563083 |
| DOK5 | docking protein 5 | -0.00562718 |
| KIF3B | kinesin family member 3B | -0.00562418 |
| VCAN | versican | -0.00562259 |
| OPHN1 | oligophrenin 1 | -0.00560799 |
| REG3A | regenerating islet-derived 3 alpha | -0.00560728 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.00560141 |
| PLA1A | phospholipase A1 member A | -0.00559622 |
| NDRG4 | NDRG family member 4 | -0.0055873 |
| GOLGA8A | golgin A8 family, member A | -0.00557532 |
| CLTB | clathrin, light chain B | -0.00557088 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | -0.00554592 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | -0.00553522 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | -0.00551877 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.00551706 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.00548364 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.00545824 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | -0.00545258 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 | -0.00542485 |
| SPATA20 | spermatogenesis associated 20 | -0.00541237 |
| ATIC | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase | -0.00540514 |
| SESN1 | sestrin 1 | -0.00540415 |
| ABHD2 | abhydrolase domain containing 2 | -0.00539819 |
| CYP27B1 | cytochrome P450, family 27, subfamily B, polypeptide 1 | -0.00538164 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | -0.0053734 |
| YLPM1 | YLP motif containing 1 | -0.0053673 |
| RPL36 | ribosomal protein L36 | -0.00534893 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.00534606 |
| CBS | cystathionine-beta-synthase | -0.00534357 |
| PGC | progastricsin (pepsinogen C) | -0.00533662 |
| NUAK1 | NUAK family, SNF1-like kinase, 1 | -0.00533038 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | -0.00531569 |
| PKD1P1 | polycystic kidney disease 1 (autosomal dominant) pseudogene 1 | -0.00529427 |
| CHMP2A | charged multivesicular body protein 2A | -0.00529382 |
| MEN1 | multiple endocrine neoplasia I | -0.00527069 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 | -0.00526713 |
| PTPRA | protein tyrosine phosphatase, receptor type, A | -0.00526408 |
| DDX39A | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A | -0.00525488 |
| SST | somatostatin | -0.00525157 |
| GAP43 | growth associated protein 43 | -0.00524433 |
| GATA6 | GATA binding protein 6 | -0.00524418 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.00522422 |
| KCNE4 | potassium channel, voltage gated subfamily E regulatory beta subunit 4 | -0.00522256 |
| EGR2 | early growth response 2 | -0.00520007 |
| PEBP1 | phosphatidylethanolamine binding protein 1 | -0.00519422 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0051937 |
| NEFM | neurofilament, medium polypeptide | -0.00518345 |
| RORA | RAR-related orphan receptor A | -0.00514569 |
| COMP | cartilage oligomeric matrix protein | -0.00514332 |
| LBH | limb bud and heart development | -0.00512591 |
| PCDH9 | protocadherin 9 | -0.00511825 |
| SH3BP4 | SH3-domain binding protein 4 | -0.00511344 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | -0.00507835 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -0.00507372 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | -0.00505842 |
| CYB561 | cytochrome b561 | -0.0050551 |
| RPL10 | ribosomal protein L10 | -0.00504821 |
| NRN1 | neuritin 1 | -0.00503079 |
| EPS8L3 | EPS8-like 3 | -0.00502785 |
| NOP53 | NOP53 ribosome biogenesis factor | -0.00502227 |
| ATP5ME | ATP synthase membrane subunit e | -0.00502043 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | -0.0050146 |
| ZNF44 | zinc finger protein 44 | -0.00500962 |
| JUND | jun D proto-oncogene | -0.00499556 |
| FCER2 | Fc fragment of IgE, low affinity II, receptor for (CD23) | -0.00498743 |
| CCNI | cyclin I | -0.00498738 |
| FHL1 | four and a half LIM domains 1 | -0.00498652 |
| SPON2 | spondin 2, extracellular matrix protein | -0.00498116 |
| RAB6B | RAB6B, member RAS oncogene family | -0.00497017 |
| RRBP1 | ribosome binding protein 1 | -0.00495343 |
| REG1A | regenerating islet-derived 1 alpha | -0.00493862 |
| CA12 | carbonic anhydrase XII | -0.00492915 |
| LRRC37A3 | leucine rich repeat containing 37, member A3 | -0.00492827 |
| WT1 | Wilms tumor 1 | -0.00491945 |
| NEK3 | NIMA-related kinase 3 | -0.00490828 |
| SOX11 | SRY (sex determining region Y)-box 11 | -0.00489589 |
| FERMT1 | fermitin family member 1 | -0.00489388 |
| NDUFA3 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa | -0.00489038 |
| HSPA12A | heat shock 70kDa protein 12A | -0.00488758 |
| DHFR | dihydrofolate reductase | -0.00488469 |
| BMP7 | bone morphogenetic protein 7 | -0.0048701 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein | -0.00486038 |
| CKMT2 | creatine kinase, mitochondrial 2 (sarcomeric) | -0.0048593 |
| AREG | amphiregulin | -0.00485375 |
| IDH3B | isocitrate dehydrogenase 3 (NAD+) beta | -0.00484561 |
| NME1 | NME/NM23 nucleoside diphosphate kinase 1 | -0.00484524 |
| TNNC1 | troponin C type 1 (slow) | -0.00483534 |
| CALB1 | calbindin 1, 28kDa | -0.00482648 |
| TBX2 | T-box 2 | -0.00482617 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 | -0.004823 |
| TMEM100 | transmembrane protein 100 | -0.00480714 |
| S100A7 | S100 calcium binding protein A7 | -0.00478671 |
| CTSE | cathepsin E | -0.00478537 |
| ZNF665 | zinc finger protein 665 | -0.00478426 |
| ZNF544 | zinc finger protein 544 | -0.004782 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.00477943 |
| MLANA | melan-A | -0.00477806 |
| SRRT | serrate, RNA effector molecule | -0.00475624 |
| HAS2 | hyaluronan synthase 2 | -0.00475581 |
| ANKRD11 | ankyrin repeat domain 11 | -0.00473935 |
| CNR1 | cannabinoid receptor 1 (brain) | -0.00473841 |
| KIF1A | kinesin family member 1A | -0.00473619 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | -0.00473119 |
| ESF1 | ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) | -0.00473046 |
| TENM4 | teneurin transmembrane protein 4 | -0.00472393 |
| RPS25 | ribosomal protein S25 | -0.00471154 |
| SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) | -0.00469698 |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) | -0.00469085 |
| CENPF | centromere protein F, 350/400kDa | -0.00468563 |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 | -0.00468378 |
| SLC22A3 | solute carrier family 22 (organic cation transporter), member 3 | -0.00467228 |
| CLNS1A | chloride channel, nucleotide-sensitive, 1A | -0.00466695 |
| SFRP4 | secreted frizzled-related protein 4 | -0.00466117 |
| MAP2K7 | mitogen-activated protein kinase kinase 7 | -0.00464842 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | -0.00463827 |
| TCEAL2 | transcription elongation factor A (SII)-like 2 | -0.00463542 |
| ILKAP | integrin-linked kinase-associated serine/threonine phosphatase | -0.00463541 |
| GPM6A | glycoprotein M6A | -0.0046319 |
| RBM34 | RNA binding motif protein 34 | -0.00463098 |
| AKAP1 | A kinase (PRKA) anchor protein 1 | -0.00462825 |
| THOC7 | THO complex 7 | -0.0046259 |
