PRKD2 Gene Set

Dataset Kinase Library Serine Threonine Kinome Atlas
Category proteomics
Type kinase
Description protein kinase D2|The protein encoded by this gene belongs to the protein kinase D (PKD) family of serine/threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans-Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 25865)
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100 substrates of the kinase PRKD2 from the Kinase Library Serine Threonine Kinome Atlas dataset.

Symbol Name Standardized Value
PPP1R3D protein phosphatase 1, regulatory subunit 3D
LEMD2 LEM domain containing 2
FAM208A family with sequence similarity 208, member A
GANAB glucosidase, alpha; neutral AB
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
SCAF1 SR-related CTD-associated factor 1
NR2C1 nuclear receptor subfamily 2, group C, member 1
APTX aprataxin
KSR1 kinase suppressor of ras 1
OSBPL5 oxysterol binding protein-like 5
PKP1 plakophilin 1
SPN sialophorin
KDM5C lysine (K)-specific demethylase 5C
FTSJ3 FtsJ homolog 3 (E. coli)
RBM8A RNA binding motif protein 8A
BPTF bromodomain PHD finger transcription factor
BOD1L1 biorientation of chromosomes in cell division 1-like 1
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
SETD2 SET domain containing 2
TLN1 talin 1
TOP2A topoisomerase (DNA) II alpha 170kDa
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
PRDM2 PR domain containing 2, with ZNF domain
NCK1 NCK adaptor protein 1
TRIM33 tripartite motif containing 33
WDR81 WD repeat domain 81
IWS1 IWS1 homolog (S. cerevisiae)
RASAL3 RAS protein activator like 3
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
PPME1 protein phosphatase methylesterase 1
SASH3 SAM and SH3 domain containing 3
PBRM1 polybromo 1
METAP2 methionyl aminopeptidase 2
FRMD4B FERM domain containing 4B
TNIK TRAF2 and NCK interacting kinase
DUSP9 dual specificity phosphatase 9
FLJ22184
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2
MEX3C mex-3 RNA binding family member C
PARP8 poly (ADP-ribose) polymerase family, member 8
MVD mevalonate (diphospho) decarboxylase
SOX9 SRY (sex determining region Y)-box 9
GOLGA5 golgin A5
RBM34 RNA binding motif protein 34
MIER1 mesoderm induction early response 1, transcriptional regulator
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma
MLPH melanophilin
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
DUSP7 dual specificity phosphatase 7
TCOF1 Treacher Collins-Franceschetti syndrome 1
AFAP1L2 actin filament associated protein 1-like 2
ANKRD33B ankyrin repeat domain 33B
URI1 URI1, prefoldin-like chaperone
RARA retinoic acid receptor, alpha
CNOT12 CCR4-NOT transcription complex subunit 12
CEP250 centrosomal protein 250kDa
UHRF1 ubiquitin-like with PHD and ring finger domains 1
SNTA1 syntrophin, alpha 1
ULK1 unc-51 like autophagy activating kinase 1
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
DRD3 dopamine receptor D3
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
DST dystonin
PHACTR4 phosphatase and actin regulator 4
PHACTR2 phosphatase and actin regulator 2
ETHE1 ethylmalonic encephalopathy 1
PCNX pecanex homolog (Drosophila)
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
HIST1H1E histone cluster 1, H1e
PYGO2 pygopus family PHD finger 2
MAP2 microtubule-associated protein 2
ILDR1 immunoglobulin-like domain containing receptor 1
ZFP91 ZFP91 zinc finger protein
TESPA1 thymocyte expressed, positive selection associated 1
RARG retinoic acid receptor, gamma
PCF11 PCF11 cleavage and polyadenylation factor subunit
KANK1 KN motif and ankyrin repeat domains 1
INCENP inner centromere protein antigens 135/155kDa
NOP56 NOP56 ribonucleoprotein
IRF2BP2 interferon regulatory factor 2 binding protein 2
IRF2BPL interferon regulatory factor 2 binding protein-like
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
SYTL1 synaptotagmin-like 1
SLC7A6OS solute carrier family 7, member 6 opposite strand
CDC25B cell division cycle 25B
PHC3 polyhomeotic homolog 3 (Drosophila)
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
SLA2 Src-like-adaptor 2
RAP1GAP RAP1 GTPase activating protein
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
ZC3H13 zinc finger CCCH-type containing 13
ZC3H14 zinc finger CCCH-type containing 14
RNF111 ring finger protein 111
GTSE1 G-2 and S-phase expressed 1
NOP2 NOP2 nucleolar protein
LOC285556 uncharacterized LOC285556
DENND4A DENN/MADD domain containing 4A
SRRM2 serine/arginine repetitive matrix 2
CDC25A cell division cycle 25A