PRKD2 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description protein kinase D2|The protein encoded by this gene belongs to the protein kinase D (PKD) family of serine/threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans-Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 25865)
External Link https://ncbi.nlm.nih.gov/gene/25865
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Genes

499 genes differentially expressed following the PRKD2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 0.0152402
C7 complement component 7 0.0149626
LCP1 lymphocyte cytosolic protein 1 (L-plastin) 0.0142196
FABP4 fatty acid binding protein 4, adipocyte 0.0138979
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 0.0131595
ABLIM1 actin binding LIM protein 1 0.01278
LGALS13 lectin, galactoside-binding, soluble, 13 0.0127408
BST2 bone marrow stromal cell antigen 2 0.0125592
ARID4A AT rich interactive domain 4A (RBP1-like) 0.0118127
NR2F2 nuclear receptor subfamily 2, group F, member 2 0.0117176
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.0116583
STK10 serine/threonine kinase 10 0.0115493
FZD6 frizzled class receptor 6 0.0109958
PDZD2 PDZ domain containing 2 0.0104782
USP6NL USP6 N-terminal like 0.0100808
NOTCH2 notch 2 0.0100138
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.00996346
PALMD palmdelphin 0.00990024
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 0.00979359
TSPYL5 TSPY-like 5 0.00977574
METTL7A methyltransferase like 7A 0.00976374
DLK1 delta-like 1 homolog (Drosophila) 0.00947134
TRIM14 tripartite motif containing 14 0.00939462
NFIB nuclear factor I/B 0.00926905
RNPS1 RNA binding protein S1, serine-rich domain 0.00912346
TM4SF1 transmembrane 4 L six family member 1 0.00910117
ARHGAP29 Rho GTPase activating protein 29 0.00904211
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.00903959
PEG10 paternally expressed 10 0.00890029
NR2F1 nuclear receptor subfamily 2, group F, member 1 0.0087497
TGM2 transglutaminase 2 0.00869893
VWF von Willebrand factor 0.00861938
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.00860082
SHCBP1 SHC SH2-domain binding protein 1 0.00855662
LPCAT1 lysophosphatidylcholine acyltransferase 1 0.00847909
PRKCA protein kinase C, alpha 0.0084755
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A 0.00842979
MAOB monoamine oxidase B 0.00842671
AHNAK AHNAK nucleoprotein 0.00841258
KCTD12 potassium channel tetramerization domain containing 12 0.00828578
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 0.00826748
XPO7 exportin 7 0.00821079
NBPF10 neuroblastoma breakpoint family, member 10 0.00817589
APLP2 amyloid beta (A4) precursor-like protein 2 0.00814299
CRABP2 cellular retinoic acid binding protein 2 0.0081372
TRPS1 trichorhinophalangeal syndrome I 0.00813002
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 0.0080944
PPL periplakin 0.00808287
KLHL23 kelch-like family member 23 0.00792241
IRAK1 interleukin-1 receptor-associated kinase 1 0.00790709
KCTD3 potassium channel tetramerization domain containing 3 0.00782748
KPNB1 karyopherin (importin) beta 1 0.00781478
CDH5 cadherin 5, type 2 (vascular endothelium) 0.00781364
HSPA1A heat shock 70kDa protein 1A 0.00775512
DPYD dihydropyrimidine dehydrogenase 0.00771087
GRAMD1C GRAM domain containing 1C 0.00769857
DHRS2 dehydrogenase/reductase (SDR family) member 2 0.00769692
LMO2 LIM domain only 2 (rhombotin-like 1) 0.00769451
OSMR oncostatin M receptor 0.00766379
TMED5 transmembrane emp24 protein transport domain containing 5 0.00762342
FXYD6 FXYD domain containing ion transport regulator 6 0.0076136
PTPRE protein tyrosine phosphatase, receptor type, E 0.00753695
CD302 CD302 molecule 0.00742844
CANX calnexin 0.00742713
ZMIZ1 zinc finger, MIZ-type containing 1 0.00740563
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1 0.00740176
S100A10 S100 calcium binding protein A10 0.00737461
JRKL JRK-like 0.00734174
DHCR24 24-dehydrocholesterol reductase 0.00732906
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 0.00731983
PROM1 prominin 1 0.00730405
TMEM100 transmembrane protein 100 0.00728528
ASCL1 achaete-scute family bHLH transcription factor 1 0.00727839
NELL1 NEL-like 1 (chicken) 0.00721223
MPZL2 myelin protein zero-like 2 0.00719284
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A 0.00719282
PXDN peroxidasin 0.00717816
KIF14 kinesin family member 14 0.00716368
EMP2 epithelial membrane protein 2 0.00708002
XIC X chromosome inactivation center 0.00707053
HACD3 3-hydroxyacyl-CoA dehydratase 3 0.00703659
CLU clusterin 0.00702252
WT1 Wilms tumor 1 0.00700401
TNS3 tensin 3 0.00700282
ADGRL2 adhesion G protein-coupled receptor L2 0.00695494
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 0.00691444
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 0.00691127
ADGRF5 adhesion G protein-coupled receptor F5 0.00689185
LAMP5 lysosomal-associated membrane protein family, member 5 0.00685483
RAD23B RAD23 homolog B (S. cerevisiae) 0.00685332
SLC35E2B solute carrier family 35, member E2B 0.0068168
MECOM MDS1 and EVI1 complex locus 0.00681223
DPYSL3 dihydropyrimidinase-like 3 0.00673919
NOTCH2NL notch 2 N-terminal like 0.00667984
ZW10 zw10 kinetochore protein 0.00665541
BCAT1 branched chain amino-acid transaminase 1, cytosolic 0.00662499
ATAD2 ATPase family, AAA domain containing 2 0.00662397
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3 0.00662268
SEC14L1 SEC14-like 1 (S. cerevisiae) 0.00661917
ESYT1 extended synaptotagmin-like protein 1 0.00661276
KIAA0100 KIAA0100 0.00657865
TACSTD2 tumor-associated calcium signal transducer 2 0.00657246
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.00655189
RBMS1 RNA binding motif, single stranded interacting protein 1 0.006531
KIF23 kinesin family member 23 0.00651629
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 0.00650299
JADE3 jade family PHD finger 3 0.00649228
TMEM45A transmembrane protein 45A 0.00648982
CPM carboxypeptidase M 0.00647797
MEX3D mex-3 RNA binding family member D 0.00644769
CFI complement factor I 0.00644606
PODXL podocalyxin-like 0.00643855
WWTR1 WW domain containing transcription regulator 1 0.00642076
PTCH1 patched 1 0.00639909
MSLN mesothelin 0.0063868
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.00637906
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 0.00637604
NCAPD3 non-SMC condensin II complex, subunit D3 0.00637454
CARD8 caspase recruitment domain family, member 8 0.00634293
CDV3 CDV3 homolog (mouse) 0.00634039
TAGLN2 transgelin 2 0.0063321
PEG3 paternally expressed 3 0.00632937
SOX11 SRY (sex determining region Y)-box 11 0.00631044
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 0.00630509
ADGRG6 adhesion G protein-coupled receptor G6 0.0063033
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 0.00629231
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 0.00628437
CSDE1 cold shock domain containing E1, RNA-binding 0.00627645
SUB1 SUB1 homolog (S. cerevisiae) 0.00626551
ALB albumin 0.00623608
TUBGCP3 tubulin, gamma complex associated protein 3 0.00621754
C4BPA complement component 4 binding protein, alpha 0.00620956
C1RL complement component 1, r subcomponent-like 0.00620059
CDC7 cell division cycle 7 0.00619358
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 0.00618132
ANOS1 anosmin 1 0.00616833
PUS7 pseudouridylate synthase 7 (putative) 0.00616514
UFM1 ubiquitin-fold modifier 1 0.0061499
NAV2 neuron navigator 2 0.00613725
ADCY3 adenylate cyclase 3 0.00612319
TSPAN13 tetraspanin 13 0.00611024
TBC1D2B TBC1 domain family, member 2B 0.00609824
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) 0.00609695
BCHE butyrylcholinesterase 0.00608233
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) 0.00606885
MGLL monoglyceride lipase 0.00604103
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae) 0.00600379
STOM stomatin 0.00599887
RAD51AP1 RAD51 associated protein 1 0.00599873
CPB2 carboxypeptidase B2 (plasma) 0.00599704
VCL vinculin 0.00599334
LAMP2 lysosomal-associated membrane protein 2 0.0059836
SUSD4 sushi domain containing 4 0.0059639
OBSL1 obscurin-like 1 0.00595217
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2) 0.00594029
ATXN7L3B ataxin 7-like 3B 0.0059395
LINC00623 long intergenic non-protein coding RNA 623 0.00592926
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 0.00592431
ADAR adenosine deaminase, RNA-specific 0.00591399
MBL2 mannose-binding lectin (protein C) 2, soluble 0.0059128
MARCO macrophage receptor with collagenous structure 0.00590999
FAM120A family with sequence similarity 120A 0.00589684
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A 0.00586377
OXTR oxytocin receptor 0.00584382
C3ORF14 chromosome 3 open reading frame 14 0.00584208
NPTX2 neuronal pentraxin II 0.00584183
IL6ST interleukin 6 signal transducer 0.00583625
NLGN4X neuroligin 4, X-linked 0.00583337
CTBP1 C-terminal binding protein 1 0.00583181
RPIA ribose 5-phosphate isomerase A 0.00579125
CD163 CD163 molecule 0.00577345
SPARCL1 SPARC-like 1 (hevin) 0.00576853
TPD52 tumor protein D52 0.00575606
PURA purine-rich element binding protein A 0.00573134
PPARG peroxisome proliferator-activated receptor gamma 0.00572806
FTO fat mass and obesity associated 0.00572523
TSFM Ts translation elongation factor, mitochondrial 0.00572351
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 0.00572222
RFC5 replication factor C (activator 1) 5, 36.5kDa 0.00571558
WASHC4 WASH complex subunit 4 0.00567566
SLF2 SMC5-SMC6 complex localization factor 2 0.00566652
CDC42 cell division cycle 42 0.00566386
SRM spermidine synthase 0.00566112
TARP TCR gamma alternate reading frame protein 0.00565072
PBX1 pre-B-cell leukemia homeobox 1 0.0056458
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) 0.00562912
GREB1 growth regulation by estrogen in breast cancer 1 0.00562824
TMBIM6 transmembrane BAX inhibitor motif containing 6 0.00562355
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3) 0.00561267
SMS spermine synthase 0.0056063
CD93 CD93 molecule 0.00560075
LIMCH1 LIM and calponin homology domains 1 0.00559291
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 0.00558389
LAMA3 laminin, alpha 3 0.00557668
MACF1 microtubule-actin crosslinking factor 1 0.00556321
ZNF512B zinc finger protein 512B 0.00555742
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit 0.00554887
SARAF store-operated calcium entry-associated regulatory factor 0.00554289
EML4 echinoderm microtubule associated protein like 4 0.00553236
ANXA3 annexin A3 0.00552987
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) 0.00552939
PBK PDZ binding kinase 0.00550018
TMED2 transmembrane emp24 domain trafficking protein 2 0.00549921
NSD2 nuclear receptor binding SET domain protein 2 0.00549737
NDFIP1 Nedd4 family interacting protein 1 0.00548346
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis) 0.00548294
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) 0.0054691
TCF21 transcription factor 21 0.00546684
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 0.00545955
TARBP1 TAR (HIV-1) RNA binding protein 1 0.00545868
IFI27 interferon, alpha-inducible protein 27 0.00544874
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 0.00544699
SRRM1 serine/arginine repetitive matrix 1 0.00544023
ADCY7 adenylate cyclase 7 0.00543563
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6 0.00543494
RTF1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) 0.00543262
RAD54B RAD54 homolog B (S. cerevisiae) 0.00543157
SRSF1 serine/arginine-rich splicing factor 1 0.00542666
SFRP1 secreted frizzled-related protein 1 0.00541881
TRIB2 tribbles pseudokinase 2 0.00541235
ICMT isoprenylcysteine carboxyl methyltransferase 0.00541057
C1ORF112 chromosome 1 open reading frame 112 0.00539567
CCNA2 cyclin A2 0.00539402
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) 0.00539209
HYAL1 hyaluronoglucosaminidase 1 0.00539147
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) 0.00538331
RFC3 replication factor C (activator 1) 3, 38kDa 0.00538179
KIF20A kinesin family member 20A 0.0053815
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 0.0053773
CNN3 calponin 3, acidic 0.00537728
SPDL1 spindle apparatus coiled-coil protein 1 0.00537656
HOPX HOP homeobox 0.00536583
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.00536382
OIP5 Opa interacting protein 5 0.00532391
SFTPD surfactant protein D 0.00532279
MT1M metallothionein 1M 0.00532106
ALDH9A1 aldehyde dehydrogenase 9 family, member A1 0.00529975
HOXA5 homeobox A5 0.00529678
SPAG16 sperm associated antigen 16 0.00529664
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.0052904
PANK3 pantothenate kinase 3 0.0052893
FBP1 fructose-1,6-bisphosphatase 1 0.00528613
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 0.00528573
CHEK1 checkpoint kinase 1 0.00528467
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 0.00528072
TRIO trio Rho guanine nucleotide exchange factor 0.00527267
MEIS2 Meis homeobox 2 0.00526976
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.00526876
SLC25A32 solute carrier family 25 (mitochondrial folate carrier), member 32 0.00526876
CHRDL1 chordin-like 1 0.0052633

decreased expression

Symbol Name Standardized Value
PCNA proliferating cell nuclear antigen -0.0296614
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.0226983
GJA1 gap junction protein, alpha 1, 43kDa -0.0161062
LTF lactotransferrin -0.0155512
POSTN periostin, osteoblast specific factor -0.0137703
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 -0.0136073
H1-2 H1.2 linker histone, cluster member -0.013456
CA12 carbonic anhydrase XII -0.0121582
HIST1H2AC histone cluster 1, H2ac -0.0121099
TFF1 trefoil factor 1 -0.0119785
TFPI2 tissue factor pathway inhibitor 2 -0.0118537
INHBA inhibin, beta A -0.0115868
AKR1C3 aldo-keto reductase family 1, member C3 -0.0115378
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -0.0111191
CXCL3 chemokine (C-X-C motif) ligand 3 -0.0111028
ASS1 argininosuccinate synthase 1 -0.010125
ADM adrenomedullin -0.0100955
MUC5B mucin 5B, oligomeric mucus/gel-forming -0.010077
THBS2 thrombospondin 2 -0.00999831
SNAP25 synaptosomal-associated protein, 25kDa -0.00995887
CRYAB crystallin, alpha B -0.00992719
BTG3 BTG family, member 3 -0.00991621
REG1A regenerating islet-derived 1 alpha -0.00985849
ST18 suppression of tumorigenicity 18, zinc finger -0.00982768
CRIP1 cysteine-rich protein 1 (intestinal) -0.00982739
KDM5D lysine (K)-specific demethylase 5D -0.00978689
COL11A1 collagen, type XI, alpha 1 -0.00971456
VEGFA vascular endothelial growth factor A -0.00953779
CA2 carbonic anhydrase II -0.00949614
GPNMB glycoprotein (transmembrane) nmb -0.00929395
S100P S100 calcium binding protein P -0.00928318
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 -0.00886228
BAMBI BMP and activin membrane-bound inhibitor -0.00868983
MFAP5 microfibrillar associated protein 5 -0.00860009
DSTN destrin (actin depolymerizing factor) -0.00851831
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 -0.00847843
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 -0.00837564
TRIB3 tribbles pseudokinase 3 -0.00832144
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 -0.00829308
CDH17 cadherin 17, LI cadherin (liver-intestine) -0.0082861
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 -0.00826562
MGAM maltase-glucoamylase -0.0082452
ATF3 activating transcription factor 3 -0.00821147
HIST1H2BD histone cluster 1, H2bd -0.00812838
NR4A3 nuclear receptor subfamily 4, group A, member 3 -0.00809862
TYMS thymidylate synthetase -0.00807975
ADCY1 adenylate cyclase 1 (brain) -0.00807489
UFD1 ubiquitin recognition factor in ER associated degradation 1 -0.00803046
IDH3B isocitrate dehydrogenase 3 (NAD+) beta -0.00799988
TUBB2A tubulin, beta 2A class IIa -0.0079883
AOC1 amine oxidase, copper containing 1 -0.00796831
C21ORF91 chromosome 21 open reading frame 91 -0.0079642
GRIA2 glutamate receptor, ionotropic, AMPA 2 -0.00796333
CKS2 CDC28 protein kinase regulatory subunit 2 -0.00795723
MMP9 matrix metallopeptidase 9 -0.00793924
NQO1 NAD(P)H dehydrogenase, quinone 1 -0.00791807
TGFBI transforming growth factor, beta-induced, 68kDa -0.00782416
DCT dopachrome tautomerase -0.007794
JCHAIN joining chain of multimeric IgA and IgM -0.00778222
GADD45A growth arrest and DNA-damage-inducible, alpha -0.00778041
ASNS asparagine synthetase (glutamine-hydrolyzing) -0.00777628
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) -0.00776986
CEMIP cell migration inducing protein, hyaluronan binding -0.00775369
CHGB chromogranin B -0.00773485
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 -0.00769152
LGALS4 lectin, galactoside-binding, soluble, 4 -0.00766907
SAT1 spermidine/spermine N1-acetyltransferase 1 -0.00765597
TPD52L1 tumor protein D52-like 1 -0.00761396
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 -0.00761297
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 -0.00760168
SELENBP1 selenium binding protein 1 -0.00758814
WNT5B wingless-type MMTV integration site family, member 5B -0.00758432
EVI2A ecotropic viral integration site 2A -0.00757891
NR4A2 nuclear receptor subfamily 4, group A, member 2 -0.00744604
DUSP2 dual specificity phosphatase 2 -0.00744506
NSFL1C NSFL1 (p97) cofactor (p47) -0.00742885
PFDN4 prefoldin subunit 4 -0.00741618
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 -0.0073721
MZB1 marginal zone B and B1 cell-specific protein -0.00734004
LARP6 La ribonucleoprotein domain family, member 6 -0.0073175
NDUFA6 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa -0.00728573
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked -0.00728126
EGR1 early growth response 1 -0.00723949
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 -0.00721866
CXADR coxsackie virus and adenovirus receptor -0.00716628
GLRX glutaredoxin (thioltransferase) -0.00713529
OLFM4 olfactomedin 4 -0.0071262
S100A13 S100 calcium binding protein A13 -0.00707672
DPEP1 dipeptidase 1 (renal) -0.00707569
CHN2 chimerin 2 -0.00698361
PPP1R15A protein phosphatase 1, regulatory subunit 15A -0.0069686
POLR1D polymerase (RNA) I polypeptide D, 16kDa -0.00696725
PANK2 pantothenate kinase 2 -0.00696557
CEL carboxyl ester lipase -0.00696341
GSTO1 glutathione S-transferase omega 1 -0.00695942
MMP1 matrix metallopeptidase 1 -0.00695506
CREB3L1 cAMP responsive element binding protein 3-like 1 -0.00694481
MUC2 mucin 2, oligomeric mucus/gel-forming -0.00691898
VPS16 vacuolar protein sorting 16 homolog (S. cerevisiae) -0.00690385
HIST1H2BK histone cluster 1, H2bk -0.00688967
NOP56 NOP56 ribonucleoprotein -0.00684912
CAPN3 calpain 3, (p94) -0.00684551
ATP5PF ATP synthase peripheral stalk subunit F6 -0.00683021
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1 -0.00682122
MAL mal, T-cell differentiation protein -0.00681935
NDUFB2 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa -0.00678426
SCGB1D2 secretoglobin, family 1D, member 2 -0.00675727
AREG amphiregulin -0.00673463
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 -0.00673277
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma -0.00673059
IGFBP5 insulin-like growth factor binding protein 5 -0.00672705
CST1 cystatin SN -0.00671057
LYRM4 LYR motif containing 4 -0.00669183
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -0.00667371
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1) -0.00666134
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15 -0.0066538
RGS1 regulator of G-protein signaling 1 -0.00663213
RANBP1 RAN binding protein 1 -0.00661427
TECR trans-2,3-enoyl-CoA reductase -0.0065736
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 -0.00657192
COL6A3 collagen, type VI, alpha 3 -0.00655252
MAGEA3 melanoma antigen family A3 -0.00653518
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 -0.00651761
KRT20 keratin 20, type I -0.00650069
ATF4 activating transcription factor 4 -0.00648714
RRBP1 ribosome binding protein 1 -0.00648334
IER5 immediate early response 5 -0.00648056
COMP cartilage oligomeric matrix protein -0.00647926
DSP desmoplakin -0.00647902
IVNS1ABP influenza virus NS1A binding protein -0.00644861
GALC galactosylceramidase -0.00644223
BUD31 BUD31 homolog (S. cerevisiae) -0.00640427
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) -0.00639036
INAVA innate immunity activator -0.00638897
DUSP14 dual specificity phosphatase 14 -0.00638354
S100A12 S100 calcium binding protein A12 -0.00637998
LPAR6 lysophosphatidic acid receptor 6 -0.00636271
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase -0.00635902
CYBRD1 cytochrome b reductase 1 -0.00635088
HDDC2 HD domain containing 2 -0.00634903
PYCARD PYD and CARD domain containing -0.00630286
MCUR1 mitochondrial calcium uniporter regulator 1 -0.00629102
NID2 nidogen 2 (osteonidogen) -0.0062704
NDUFA4 NDUFA4, mitochondrial complex associated -0.00626955
CHKB choline kinase beta -0.00626911
IFRD1 interferon-related developmental regulator 1 -0.00626128
GPR137B G protein-coupled receptor 137B -0.00625365
CYTIP cytohesin 1 interacting protein -0.00624065
SNAI2 snail family zinc finger 2 -0.00623008
FCGBP Fc fragment of IgG binding protein -0.00622855
RPS27L ribosomal protein S27-like -0.00620172
HIST2H2BE histone cluster 2, H2be -0.00619723
BTG1 B-cell translocation gene 1, anti-proliferative -0.00616667
SNRPB2 small nuclear ribonucleoprotein polypeptide B -0.00616254
IFT20 intraflagellar transport 20 -0.00614757
HBD hemoglobin, delta -0.00612745
TPST2 tyrosylprotein sulfotransferase 2 -0.00612533
SALL1 spalt-like transcription factor 1 -0.00609559
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 -0.00608387
PRUNE2 prune homolog 2 (Drosophila) -0.00607593
COX7A2 cytochrome c oxidase subunit VIIa polypeptide 2 (liver) -0.0060729
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -0.00606845
ZNF91 zinc finger protein 91 -0.00605931
COL1A2 collagen, type I, alpha 2 -0.0060433
VSNL1 visinin-like 1 -0.00603979
PIGR polymeric immunoglobulin receptor -0.00603936
QPCT glutaminyl-peptide cyclotransferase -0.00603903
GSTT1 glutathione S-transferase theta 1 -0.00601391
ASPA aspartoacylase -0.00599309
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) -0.00597502
LSM1 LSM1, U6 small nuclear RNA associated -0.00597365
OLFML3 olfactomedin-like 3 -0.00597256
ACO2 aconitase 2, mitochondrial -0.00596871
TPSAB1 tryptase alpha/beta 1 -0.00596277
ZNF331 zinc finger protein 331 -0.00595562
HSPA6 heat shock 70kDa protein 6 (HSP70B') -0.00594784
NXT1 nuclear transport factor 2-like export factor 1 -0.00594676
VEGFC vascular endothelial growth factor C -0.00593988
CREM cAMP responsive element modulator -0.00593763
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase) -0.00588708
FXYD2 FXYD domain containing ion transport regulator 2 -0.00588337
JAG1 jagged 1 -0.00587797
DUOX2 dual oxidase 2 -0.00586902
MAP1A microtubule-associated protein 1A -0.00586383
SATB2 SATB homeobox 2 -0.00586306
UPP1 uridine phosphorylase 1 -0.00585563
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) -0.00581925
PMM1 phosphomannomutase 1 -0.00581801
IL6 interleukin 6 -0.00581085
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 -0.00580587
CTSK cathepsin K -0.0058019
TMEM230 transmembrane protein 230 -0.0057825
BPI bactericidal/permeability-increasing protein -0.00578118
FXR1 fragile X mental retardation, autosomal homolog 1 -0.00575847
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) -0.00575292
USH1C Usher syndrome 1C (autosomal recessive, severe) -0.00574388
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 -0.00573911
NTS neurotensin -0.00572027
CSNK2A1 casein kinase 2, alpha 1 polypeptide -0.00571211
NQO2 NAD(P)H dehydrogenase, quinone 2 -0.00571115
LGALS3 lectin, galactoside-binding, soluble, 3 -0.00570356
DDRGK1 DDRGK domain containing 1 -0.00570029
COL5A2 collagen, type V, alpha 2 -0.00569935
FTH1 ferritin, heavy polypeptide 1 -0.00568935
DEPTOR DEP domain containing MTOR-interacting protein -0.00565636
ETFB electron-transfer-flavoprotein, beta polypeptide -0.00565525
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 -0.00565194
SLC17A3 solute carrier family 17 (organic anion transporter), member 3 -0.0056466
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 -0.00564435
NOP53 NOP53 ribosome biogenesis factor -0.00562784
MSMB microseminoprotein, beta- -0.00562369
COL9A2 collagen, type IX, alpha 2 -0.00559949
STX8 syntaxin 8 -0.00556846
ZC3H12A zinc finger CCCH-type containing 12A -0.00555228
CST7 cystatin F (leukocystatin) -0.00554104
CGGBP1 CGG triplet repeat binding protein 1 -0.00553461
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D -0.00552316
DPM3 dolichyl-phosphate mannosyltransferase polypeptide 3 -0.00551354
DIPK1A divergent protein kinase domain 1A -0.0055089
TG thyroglobulin -0.00550616
MYRF myelin regulatory factor -0.00549748
MMP8 matrix metallopeptidase 8 -0.00547676
SLC25A46 solute carrier family 25, member 46 -0.00546407
CLC Charcot-Leyden crystal galectin -0.00544955
VCAM1 vascular cell adhesion molecule 1 -0.00544496
PLPP3 phospholipid phosphatase 3 -0.00544092
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -0.00543804
ACKR3 atypical chemokine receptor 3 -0.00543303
COPZ2 coatomer protein complex, subunit zeta 2 -0.00543008
VIL1 villin 1 -0.00542991
DUSP5 dual specificity phosphatase 5 -0.00541474
MRPL40 mitochondrial ribosomal protein L40 -0.00540785
STAT4 signal transducer and activator of transcription 4 -0.0053966
IGFBP6 insulin-like growth factor binding protein 6 -0.00539358
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2 -0.00538997
SSX1 synovial sarcoma, X breakpoint 1 -0.00538348
CCND2 cyclin D2 -0.00537952
NKX3-1 NK3 homeobox 1 -0.00533801
LRRC15 leucine rich repeat containing 15 -0.00532933
KLF4 Kruppel-like factor 4 (gut) -0.00531058
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 -0.00529546
NDUFB1 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa -0.00529012
H2AX H2A.X variant histone -0.00529009
BMP2 bone morphogenetic protein 2 -0.00528736
ISYNA1 inositol-3-phosphate synthase 1 -0.00528507
CYFIP2 cytoplasmic FMR1 interacting protein 2 -0.00527829
RABAC1 Rab acceptor 1 (prenylated) -0.00527476
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7 -0.00526862
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 -0.00526601