PRKD2 Gene Set

Dataset PhosphoSitePlus Substrates of Kinases
Category physical interactions
Type kinase
Description protein kinase D2|The protein encoded by this gene belongs to the protein kinase D (PKD) family of serine/threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans-Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 25865)
External Link http://www.ncbi.nlm.nih.gov/gene/25865
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Genes

10 substrates of the kinase PRKD2 from the curated PhosphoSitePlus Substrates of Kinases dataset.

Symbol Name
CIB1 calcium and integrin binding 1 (calmyrin)
HDAC5 histone deacetylase 5
MARK2 MAP/microtubule affinity-regulating kinase 2
PI4KB phosphatidylinositol 4-kinase, catalytic, beta
PKD2 polycystic kidney disease 2 (autosomal dominant)
PRKD1 protein kinase D1
PRKD2 protein kinase D2
RIN1 Ras and Rab interactor 1
SET SET nuclear proto-oncogene
SSH1 slingshot protein phosphatase 1