PRL Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description prolactin|This gene encodes the anterior pituitary hormone prolactin. This secreted hormone is a growth regulator for many tissues, including cells of the immune system. It may also play a role in cell survival by suppressing apoptosis, and it is essential for lactation. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011] (NCBI Entrez Gene Database, 5617)
External Link https://ncbi.nlm.nih.gov/gene/5617
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Genes

499 genes differentially expressed following the PRL gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
PDZK1IP1 PDZK1 interacting protein 1 0.0135962
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 0.0133327
MMP7 matrix metallopeptidase 7 0.0129393
GAS1 growth arrest-specific 1 0.0129339
NNMT nicotinamide N-methyltransferase 0.0129277
FABP7 fatty acid binding protein 7, brain 0.012004
NEBL nebulette 0.0119629
PDLIM3 PDZ and LIM domain 3 0.0119509
PRUNE2 prune homolog 2 (Drosophila) 0.0118506
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 0.0117616
DLK1 delta-like 1 homolog (Drosophila) 0.0113282
MB myoglobin 0.010998
MSLN mesothelin 0.0108512
VCAM1 vascular cell adhesion molecule 1 0.0107153
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 0.010591
GALC galactosylceramidase 0.0105285
EIF5A eukaryotic translation initiation factor 5A 0.0105234
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.010503
C3 complement component 3 0.0103195
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 0.00993124
LCN2 lipocalin 2 0.00992807
CFB complement factor B 0.00986795
TMEM158 transmembrane protein 158 (gene/pseudogene) 0.00984138
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 0.00982467
AHNAK2 AHNAK nucleoprotein 2 0.00980288
PROM1 prominin 1 0.00970062
BHLHE41 basic helix-loop-helix family, member e41 0.00962428
LY75 lymphocyte antigen 75 0.009301
LTF lactotransferrin 0.00925519
BIN1 bridging integrator 1 0.00910918
CRISP3 cysteine-rich secretory protein 3 0.00905657
FAM171A1 family with sequence similarity 171, member A1 0.00904362
NIBAN1 niban apoptosis regulator 1 0.00901435
FMO1 flavin containing monooxygenase 1 0.00894918
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 0.00891601
KLK10 kallikrein-related peptidase 10 0.00890406
LST1 leukocyte specific transcript 1 0.00889931
MAN1C1 mannosidase, alpha, class 1C, member 1 0.00889541
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 0.00887841
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 0.00886222
ACP3 acid phosphatase 3 0.00875485
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 0.00874458
PITX3 paired-like homeodomain 3 0.00869193
RPS4Y1 ribosomal protein S4, Y-linked 1 0.00865011
HOXB2 homeobox B2 0.00860035
CX3CR1 chemokine (C-X3-C motif) receptor 1 0.00837213
PUF60 poly-U binding splicing factor 60KDa 0.00831487
KRT23 keratin 23, type I 0.00828753
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 0.00824449
SOD2 superoxide dismutase 2, mitochondrial 0.00823873
ACTA1 actin, alpha 1, skeletal muscle 0.00822136
ABLIM1 actin binding LIM protein 1 0.00818873
LMO2 LIM domain only 2 (rhombotin-like 1) 0.0081731
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.00817269
GUCY1A3 guanylate cyclase 1, soluble, alpha 3 0.00816279
CLEC7A C-type lectin domain family 7, member A 0.00814772
ZNF185 zinc finger protein 185 (LIM domain) 0.00813054
CRYAB crystallin, alpha B 0.00800761
CLU clusterin 0.00796867
ADD3 adducin 3 (gamma) 0.00796069
MEIS1 Meis homeobox 1 0.00789731
RAI14 retinoic acid induced 14 0.00787928
TNFAIP2 tumor necrosis factor, alpha-induced protein 2 0.00787699
KLK6 kallikrein-related peptidase 6 0.0078466
LOXL2 lysyl oxidase-like 2 0.00774113
MAP7 microtubule-associated protein 7 0.00773294
WT1 Wilms tumor 1 0.0076824
NUSAP1 nucleolar and spindle associated protein 1 0.00768131
PI3 peptidase inhibitor 3, skin-derived 0.00766418
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 0.00759773
SSPN sarcospan 0.00751361
IDO1 indoleamine 2,3-dioxygenase 1 0.00750732
BIRC3 baculoviral IAP repeat containing 3 0.00749233
PEG3 paternally expressed 3 0.00749034
CP ceruloplasmin (ferroxidase) 0.00745991
COL6A2 collagen, type VI, alpha 2 0.00745941
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 0.00744646
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney) 0.00744394
COL6A1 collagen, type VI, alpha 1 0.00744308
MPHOSPH8 M-phase phosphoprotein 8 0.00740467
RGS4 regulator of G-protein signaling 4 0.00736979
GMPR guanosine monophosphate reductase 0.0073551
COL6A3 collagen, type VI, alpha 3 0.00734394
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G 0.00733649
KLK8 kallikrein-related peptidase 8 0.00733246
TRIB2 tribbles pseudokinase 2 0.00733163
TNNT1 troponin T type 1 (skeletal, slow) 0.00719009
LGALS2 lectin, galactoside-binding, soluble, 2 0.00716164
TSPYL5 TSPY-like 5 0.00714595
HOPX HOP homeobox 0.0071104
IGFBP5 insulin-like growth factor binding protein 5 0.00710704
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 0.00705343
CLDN10 claudin 10 0.00704315
GTPBP8 GTP-binding protein 8 (putative) 0.00699223
CALML5 calmodulin-like 5 0.00698363
MYRF myelin regulatory factor 0.00696636
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 0.00695273
PER2 period circadian clock 2 0.00693297
PITX1 paired-like homeodomain 1 0.00692396
GJA1 gap junction protein, alpha 1, 43kDa 0.00690931
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.00690169
CETN2 centrin, EF-hand protein, 2 0.00689489
DOK5 docking protein 5 0.00689347
KLK7 kallikrein-related peptidase 7 0.00689045
RNF167 ring finger protein 167 0.00688604
MME membrane metallo-endopeptidase 0.00688326
PDZD8 PDZ domain containing 8 0.00688117
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 0.0068789
BICC1 BicC family RNA binding protein 1 0.00683681
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 0.00682298
TPM2 tropomyosin 2 (beta) 0.00681575
STC1 stanniocalcin 1 0.00678135
NTS neurotensin 0.00677476
IL7R interleukin 7 receptor 0.00676433
SPON1 spondin 1, extracellular matrix protein 0.00675589
FXYD2 FXYD domain containing ion transport regulator 2 0.00675543
ALOX5 arachidonate 5-lipoxygenase 0.00673566
NR2F2 nuclear receptor subfamily 2, group F, member 2 0.00673415
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 0.00671746
S100A8 S100 calcium binding protein A8 0.00668267
LDOC1 leucine zipper, down-regulated in cancer 1 0.00665401
TNS3 tensin 3 0.00661624
PTP4A3 protein tyrosine phosphatase type IVA, member 3 0.00661528
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein 0.00661461
CYBB cytochrome b-245, beta polypeptide 0.00661179
ARHGAP6 Rho GTPase activating protein 6 0.00660083
MAL mal, T-cell differentiation protein 0.00656581
PRKACB protein kinase, cAMP-dependent, catalytic, beta 0.00654726
ISLR immunoglobulin superfamily containing leucine-rich repeat 0.00653959
KRT81 keratin 81, type II 0.00653526
GREM1 gremlin 1, DAN family BMP antagonist 0.00652317
KAZN kazrin, periplakin interacting protein 0.00649906
MEIS2 Meis homeobox 2 0.00644082
CBX7 chromobox homolog 7 0.00643312
VCAN versican 0.00640184
SLC44A4 solute carrier family 44, member 4 0.0063993
SLN sarcolipin 0.00638016
YBX3 Y box binding protein 3 0.00636942
DEFB1 defensin, beta 1 0.0063641
LAT2 linker for activation of T cells family, member 2 0.0063435
MSMO1 methylsterol monooxygenase 1 0.00634334
TST thiosulfate sulfurtransferase (rhodanese) 0.00632331
PDZRN3 PDZ domain containing ring finger 3 0.00632285
PYGB phosphorylase, glycogen; brain 0.0063139
LDB3 LIM domain binding 3 0.00628678
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 0.00628171
CKM creatine kinase, muscle 0.00627925
GPX1 glutathione peroxidase 1 0.00627631
NPY neuropeptide Y 0.00624051
P3H2 prolyl 3-hydroxylase 2 0.00620714
ZNF264 zinc finger protein 264 0.006206
LAPTM4B lysosomal protein transmembrane 4 beta 0.006184
CSTA cystatin A (stefin A) 0.00617981
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 0.00617976
NID2 nidogen 2 (osteonidogen) 0.0061743
MDK midkine (neurite growth-promoting factor 2) 0.00613409
MAOB monoamine oxidase B 0.00611252
RTN1 reticulon 1 0.00610046
C1R complement component 1, r subcomponent 0.00609735
SFRP1 secreted frizzled-related protein 1 0.00608973
EHF ets homologous factor 0.00608311
RTN2 reticulon 2 0.00606746
GRIA2 glutamate receptor, ionotropic, AMPA 2 0.0060522
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase 0.00601967
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 0.00600737
NMU neuromedin U 0.00600584
C10ORF10 chromosome 10 open reading frame 10 0.00599701
CTBP2 C-terminal binding protein 2 0.00597821
EREG epiregulin 0.00596856
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 0.00596599
KLHL41 kelch-like family member 41 0.00596338
PRKCA protein kinase C, alpha 0.00596157
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) 0.00595927
REG1A regenerating islet-derived 1 alpha 0.00592589
VEGFA vascular endothelial growth factor A 0.00592383
BMP7 bone morphogenetic protein 7 0.00588965
KLK11 kallikrein-related peptidase 11 0.00588509
NSDHL NAD(P) dependent steroid dehydrogenase-like 0.00588401
TMPRSS4 transmembrane protease, serine 4 0.00587796
FYB1 FYN binding protein 1 0.00586905
HOXB6 homeobox B6 0.00586006
WNT5A wingless-type MMTV integration site family, member 5A 0.00585903
MYL2 myosin, light chain 2, regulatory, cardiac, slow 0.00584398
CHI3L2 chitinase 3-like 2 0.00584385
TEAD4 TEA domain family member 4 0.0058294
DEPTOR DEP domain containing MTOR-interacting protein 0.00582202
SOX9 SRY (sex determining region Y)-box 9 0.0058218
TRIM29 tripartite motif containing 29 0.00580818
MBOAT2 membrane bound O-acyltransferase domain containing 2 0.00579979
GUCY1B3 guanylate cyclase 1, soluble, beta 3 0.00577794
TLE4 transducin-like enhancer of split 4 0.00577595
UROD uroporphyrinogen decarboxylase 0.00577409
IQCG IQ motif containing G 0.00577326
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 0.00577324
PPP1R3C protein phosphatase 1, regulatory subunit 3C 0.00575928
IRS2 insulin receptor substrate 2 0.00575671
VWA5A von Willebrand factor A domain containing 5A 0.00573823
AQP3 aquaporin 3 (Gill blood group) 0.00573647
WWTR1 WW domain containing transcription regulator 1 0.00573511
NPAS2 neuronal PAS domain protein 2 0.00572446
SMAD3 SMAD family member 3 0.00572188
RPA2 replication protein A2, 32kDa 0.00571513
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 0.00570465
PFKM phosphofructokinase, muscle 0.00569473
TPPP3 tubulin polymerization-promoting protein family member 3 0.00569424
KYNU kynureninase 0.00568779
TRIM16 tripartite motif containing 16 0.00568376
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) 0.00568083
DENND3 DENN/MADD domain containing 3 0.00567605
ANK2 ankyrin 2, neuronal 0.00566109
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A 0.00565926
FTH1 ferritin, heavy polypeptide 1 0.00564993
GTF3A general transcription factor IIIA 0.00564979
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 0.00563981
NR2F1 nuclear receptor subfamily 2, group F, member 1 0.00559066
PNMA8A PNMA family member 8A 0.00558757
RFTN1 raftlin, lipid raft linker 1 0.00558598
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.00558271
LXN latexin 0.00557911
MYL1 myosin, light chain 1, alkali; skeletal, fast 0.00557596
LPAR1 lysophosphatidic acid receptor 1 0.00556664
SYNM synemin, intermediate filament protein 0.00556543
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) 0.00554335
MSRB2 methionine sulfoxide reductase B2 0.00554095
FZD7 frizzled class receptor 7 0.00553452
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) 0.00553222
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila) 0.00551748
TSC22D1 TSC22 domain family, member 1 0.00550132
ENC1 ectodermal-neural cortex 1 (with BTB domain) 0.00549988
GREB1 growth regulation by estrogen in breast cancer 1 0.00549511
EFNB2 ephrin-B2 0.00548009
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase 0.00547248
SPON2 spondin 2, extracellular matrix protein 0.00546834
ZNF217 zinc finger protein 217 0.00543626
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 0.00543564
CCL20 chemokine (C-C motif) ligand 20 0.00541813
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.00541456
ACTN2 actinin, alpha 2 0.00541286
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase 0.00539487
PEPD peptidase D 0.00539269
LYN LYN proto-oncogene, Src family tyrosine kinase 0.005374
FADS1 fatty acid desaturase 1 0.005351
PTN pleiotrophin 0.00534997
FOLR1 folate receptor 1 (adult) 0.00534425
MIPEP mitochondrial intermediate peptidase 0.00533893
DUSP3 dual specificity phosphatase 3 0.00533067
C1S complement component 1, s subcomponent 0.00532925
GCH1 GTP cyclohydrolase 1 0.00531506
TRAPPC3 trafficking protein particle complex 3 0.00530178
PIM1 Pim-1 proto-oncogene, serine/threonine kinase 0.00530006

decreased expression

Symbol Name Standardized Value
PWP1 PWP1 homolog (S. cerevisiae) -0.0110317
HSPA1A heat shock 70kDa protein 1A -0.0107654
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.0103039
STK10 serine/threonine kinase 10 -0.00897445
S100A10 S100 calcium binding protein A10 -0.00880545
MYO1B myosin IB -0.00871755
MAGEA12 melanoma antigen family A12 -0.00866163
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -0.00865168
MNAT1 MNAT CDK-activating kinase assembly factor 1 -0.00849692
DMTF1 cyclin D binding myb-like transcription factor 1 -0.00834763
MAGEA3 melanoma antigen family A3 -0.00825982
CCL14 chemokine (C-C motif) ligand 14 -0.00825825
ELL2 elongation factor, RNA polymerase II, 2 -0.008221
SGPP1 sphingosine-1-phosphate phosphatase 1 -0.00818969
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) -0.00808312
SFTPB surfactant protein B -0.00800549
ADK adenosine kinase -0.00791461
RAB38 RAB38, member RAS oncogene family -0.007823
RHOB ras homolog family member B -0.0074627
CADM1 cell adhesion molecule 1 -0.00742634
GAB2 GRB2-associated binding protein 2 -0.00719294
MT1H metallothionein 1H -0.00708991
NKX2-1 NK2 homeobox 1 -0.00704677
EXOC5 exocyst complex component 5 -0.007041
TENT5A terminal nucleotidyltransferase 5A -0.00696952
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -0.00681113
ISG15 ISG15 ubiquitin-like modifier -0.00679807
RNPS1 RNA binding protein S1, serine-rich domain -0.00669506
TNIP1 TNFAIP3 interacting protein 1 -0.00660744
MECOM MDS1 and EVI1 complex locus -0.00656132
HACD3 3-hydroxyacyl-CoA dehydratase 3 -0.00654794
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4 -0.00651849
GUSBP3 glucuronidase, beta pseudogene 3 -0.00650417
IFI27 interferon, alpha-inducible protein 27 -0.00649461
DSTN destrin (actin depolymerizing factor) -0.00647959
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 -0.00647521
FAM3C family with sequence similarity 3, member C -0.00646552
CTSZ cathepsin Z -0.00640758
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 -0.00629868
CLCA1 chloride channel accessory 1 -0.00627443
BCAR3 breast cancer anti-estrogen resistance 3 -0.00626737
PAWR PRKC, apoptosis, WT1, regulator -0.00624409
GOLGA8A golgin A8 family, member A -0.00623997
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.00619526
LRP4 low density lipoprotein receptor-related protein 4 -0.00618205
CTH cystathionine gamma-lyase -0.0061548
PERP PERP, TP53 apoptosis effector -0.00614097
MPDZ multiple PDZ domain protein -0.00612211
FRS2 fibroblast growth factor receptor substrate 2 -0.00611284
SRSF1 serine/arginine-rich splicing factor 1 -0.00609209
MT1E metallothionein 1E -0.00599919
MT1HL1 metallothionein 1H-like 1 -0.00598878
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit -0.00597232
UBR5 ubiquitin protein ligase E3 component n-recognin 5 -0.0059438
USP6NL USP6 N-terminal like -0.00593091
MAN2A1 mannosidase, alpha, class 2A, member 1 -0.00590414
SATB2 SATB homeobox 2 -0.00589345
LMO3 LIM domain only 3 (rhombotin-like 2) -0.00576132
TPD52 tumor protein D52 -0.005745
ASCL1 achaete-scute family bHLH transcription factor 1 -0.00573964
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 -0.00571856
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 -0.00571595
ZNF281 zinc finger protein 281 -0.00567681
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -0.0056709
MAOA monoamine oxidase A -0.00564587
HSPA4L heat shock 70kDa protein 4-like -0.0056005
TPBG trophoblast glycoprotein -0.00558681
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 -0.00556455
SCAF11 SR-related CTD-associated factor 11 -0.00553129
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 -0.00552624
SPTSSA serine palmitoyltransferase, small subunit A -0.00551963
KIF14 kinesin family member 14 -0.00546584
OGA O-GlcNAcase -0.00545874
S100A11 S100 calcium binding protein A11 -0.00542126
SMYD2 SET and MYND domain containing 2 -0.00540577
RPS26 ribosomal protein S26 -0.00539856
PPARG peroxisome proliferator-activated receptor gamma -0.00538846
ISCU iron-sulfur cluster assembly enzyme -0.00537771
RUBCN rubicon autophagy regulator -0.00537632
REEP5 receptor accessory protein 5 -0.00536996
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -0.00533365
MSX1 msh homeobox 1 -0.00532369
SCAMP1 secretory carrier membrane protein 1 -0.00531852
ACAA2 acetyl-CoA acyltransferase 2 -0.00530888
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 -0.00530841
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 -0.0053068
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15 -0.00527423
SLC26A2 solute carrier family 26 (anion exchanger), member 2 -0.00527285
ABCA6 ATP-binding cassette, sub-family A (ABC1), member 6 -0.00527264
MT2A metallothionein 2A -0.00526081
KPNB1 karyopherin (importin) beta 1 -0.00524542
C9 complement component 9 -0.00522565
ZG16 zymogen granule protein 16 -0.00520979
EDNRB endothelin receptor type B -0.00519628
ATG5 autophagy related 5 -0.00518535
C4BPA complement component 4 binding protein, alpha -0.00518445
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 -0.00517661
WAC WW domain containing adaptor with coiled-coil -0.00517299
BAAT bile acid CoA:amino acid N-acyltransferase -0.00516736
KANK1 KN motif and ankyrin repeat domains 1 -0.00515104
UBE2E3 ubiquitin-conjugating enzyme E2E 3 -0.00514427
SMAD4 SMAD family member 4 -0.00513446
CACYBP calcyclin binding protein -0.00513302
MAGEA1 melanoma antigen family A1 -0.00512353
PON3 paraoxonase 3 -0.00510795
COX17 COX17 cytochrome c oxidase copper chaperone -0.00510728
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 -0.00510535
GOLM1 golgi membrane protein 1 -0.005096
TAGLN2 transgelin 2 -0.00508871
CFHR4 complement factor H-related 4 -0.00508661
CHEK1 checkpoint kinase 1 -0.00508051
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) -0.00507734
SEC61B Sec61 beta subunit -0.00506177
SIRT3 sirtuin 3 -0.00505153
AHCYL2 adenosylhomocysteinase-like 2 -0.00504289
RBM47 RNA binding motif protein 47 -0.00504127
MYH11 myosin, heavy chain 11, smooth muscle -0.00502269
FERMT1 fermitin family member 1 -0.0050196
MRPS30 mitochondrial ribosomal protein S30 -0.0049932
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa -0.00497545
CORO1C coronin, actin binding protein, 1C -0.00495815
ALG8 ALG8, alpha-1,3-glucosyltransferase -0.00492654
IRF4 interferon regulatory factor 4 -0.00491506
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 -0.00490651
HOMER1 homer scaffolding protein 1 -0.00489312
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 -0.00488724
LGALS4 lectin, galactoside-binding, soluble, 4 -0.00487614
FABP1 fatty acid binding protein 1, liver -0.00486905
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa -0.00486089
CXADR coxsackie virus and adenovirus receptor -0.00485959
CCDC92 coiled-coil domain containing 92 -0.00485895
XAF1 XIAP associated factor 1 -0.00483909
TSPAN7 tetraspanin 7 -0.00483511
CHKA choline kinase alpha -0.0048284
SIGMAR1 sigma non-opioid intracellular receptor 1 -0.00482793
ADGRE2 adhesion G protein-coupled receptor E2 -0.00480951
GADD45B growth arrest and DNA-damage-inducible, beta -0.0048049
SLC39A6 solute carrier family 39 (zinc transporter), member 6 -0.00480197
TSPAN13 tetraspanin 13 -0.00479113
LMAN1 lectin, mannose-binding, 1 -0.00478915
MT1X metallothionein 1X -0.00478623
PLK1 polo-like kinase 1 -0.00475396
MAP1LC3B microtubule-associated protein 1 light chain 3 beta -0.00475142
CEP350 centrosomal protein 350kDa -0.004749
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 -0.00474824
JUNB jun B proto-oncogene -0.00474049
PLS3 plastin 3 -0.00473456
ZMYND11 zinc finger, MYND-type containing 11 -0.00471151
SLC6A15 solute carrier family 6 (neutral amino acid transporter), member 15 -0.00470215
SFTPD surfactant protein D -0.00469668
GOLT1B golgi transport 1B -0.00469533
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.00469435
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1 -0.00468553
ADGRF5 adhesion G protein-coupled receptor F5 -0.00465963
BTG1 B-cell translocation gene 1, anti-proliferative -0.00465457
RNFT1 ring finger protein, transmembrane 1 -0.00464212
CES1 carboxylesterase 1 -0.00463533
PHLDA1 pleckstrin homology-like domain, family A, member 1 -0.00463241
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha -0.00462509
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 -0.00461908
RAD21 RAD21 homolog (S. pombe) -0.0046188
LUM lumican -0.00461708
MERTK MER proto-oncogene, tyrosine kinase -0.0046102
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 -0.00460378
SPAG9 sperm associated antigen 9 -0.00459654
TMEM87A transmembrane protein 87A -0.00459185
TCF12 transcription factor 12 -0.00458876
CTSC cathepsin C -0.00458876
LPPR1 lipid phosphate phosphatase-related protein type 1 -0.00458006
STXBP6 syntaxin binding protein 6 (amisyn) -0.00457372
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta -0.00456634
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) -0.00455996
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) -0.00455639
ARHGAP12 Rho GTPase activating protein 12 -0.00454916
HIP1 huntingtin interacting protein 1 -0.00453673
AGR2 anterior gradient 2 -0.00453119
RPL36 ribosomal protein L36 -0.00452644
MX1 MX dynamin-like GTPase 1 -0.0045213
ZNF165 zinc finger protein 165 -0.00451102
SEPP1 selenoprotein P, plasma, 1 -0.00449841
SFTPC surfactant protein C -0.00449764
SLC25A46 solute carrier family 25, member 46 -0.00449391
CSNK1A1 casein kinase 1, alpha 1 -0.00448801
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 -0.00447785
GNA13 guanine nucleotide binding protein (G protein), alpha 13 -0.00446893
MBIP MAP3K12 binding inhibitory protein 1 -0.00445386
CFD complement factor D (adipsin) -0.00444959
IGHMBP2 immunoglobulin mu binding protein 2 -0.00444123
TPTE transmembrane phosphatase with tensin homology -0.00443341
HSPA2 heat shock 70kDa protein 2 -0.00442811
SNAPC3 small nuclear RNA activating complex, polypeptide 3, 50kDa -0.0044185
ANKFY1 ankyrin repeat and FYVE domain containing 1 -0.00441814
TBC1D9B TBC1 domain family, member 9B (with GRAM domain) -0.00440504
FAM169A family with sequence similarity 169, member A -0.00439948
DENND4C DENN/MADD domain containing 4C -0.00439775
CD320 CD320 molecule -0.00438346
BTG3 BTG family, member 3 -0.00437308
KLHL23 kelch-like family member 23 -0.00436484
COG2 component of oligomeric golgi complex 2 -0.00436053
MYRIP myosin VIIA and Rab interacting protein -0.00435265
ACP1 acid phosphatase 1, soluble -0.0043524
UHRF1BP1L UHRF1 binding protein 1-like -0.00434948
SSX1 synovial sarcoma, X breakpoint 1 -0.00434702
RNF13 ring finger protein 13 -0.00434678
BRD2 bromodomain containing 2 -0.00433461
BCAT1 branched chain amino-acid transaminase 1, cytosolic -0.00433393
TRIB3 tribbles pseudokinase 3 -0.00432621
ENAH enabled homolog (Drosophila) -0.00432534
SMS spermine synthase -0.00432292
KDM3A lysine (K)-specific demethylase 3A -0.00431722
EPB41L4B erythrocyte membrane protein band 4.1 like 4B -0.00430543
CPB2 carboxypeptidase B2 (plasma) -0.00429249
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa -0.00428661
EPS8 epidermal growth factor receptor pathway substrate 8 -0.00428646
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 -0.00428509
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide -0.00428126
PHACTR2 phosphatase and actin regulator 2 -0.00427706
PRRC2C proline-rich coiled-coil 2C -0.00427644
YIPF5 Yip1 domain family, member 5 -0.00427373
UNC45A unc-45 homolog A (C. elegans) -0.00426571
TTC39A tetratricopeptide repeat domain 39A -0.00425033
DUSP12 dual specificity phosphatase 12 -0.00424832
YAF2 YY1 associated factor 2 -0.00424474
KPNA4 karyopherin alpha 4 (importin alpha 3) -0.00423878
RIOX2 ribosomal oxygenase 2 -0.00423576
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 -0.00423441
COX6A1 cytochrome c oxidase subunit VIa polypeptide 1 -0.00423191
ARG2 arginase 2 -0.00423086
CUL1 cullin 1 -0.00422979
PIGG phosphatidylinositol glycan anchor biosynthesis, class G -0.00422879
MYO9B myosin IXB -0.00422541
TEX10 testis expressed 10 -0.00422461
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide -0.00422434
AHNAK AHNAK nucleoprotein -0.00422199
SCARB2 scavenger receptor class B, member 2 -0.00421107
HEBP2 heme binding protein 2 -0.00420856
POSTN periostin, osteoblast specific factor -0.00420776
GPATCH8 G patch domain containing 8 -0.00420424
MMP2 matrix metallopeptidase 2 -0.00419949
ABHD4 abhydrolase domain containing 4 -0.00419772
TNPO3 transportin 3 -0.00419675
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae) -0.004196
ZBTB1 zinc finger and BTB domain containing 1 -0.00419257
KMT5B lysine methyltransferase 5B -0.00417822
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 -0.00417331
FNDC3A fibronectin type III domain containing 3A -0.00417092
HPR haptoglobin-related protein -0.00416905
SEC61G Sec61 gamma subunit -0.00416853
MYO1D myosin ID -0.00416651